A retrospective analysis on maternal and neonatal outcomes in pSS/AITD pregnancies by Miaoguan Peng, Taizhen Luo, Xiaoshi Weng, Yanmei Dong, Yijuan Xie, Siqi Huang, Naifeng Liang, Shiyun Wen, Yaojie Zhai, Yingjun Xie, Yuyi Chen

“…In the group with pSS and AITD, the pregnancy loss rate was significantly higher than in the non-AITD group (P = 0.015), primarily reflected in the increased rate of neonatal death (P = 0.029). …”
Get full text

Liver cancer risk and changes in lifestyle habits after successful hepatitis C virus therapy post-DAA HCV therapy: lifestyle changes and liver cancer risk by Núria Granel, Gemma Iserte, Concepció Bartres, Neus Llarch, Anna Pla, Víctor Sapena, Zoe Mariño, Sabela Lens, Ramón Vilana, Isabel Nuñez, Anna Darnell, Ernest Belmonte, Ángeles García-Criado, Alba Díaz, Marco Sanduzzi-Zamparelli, Carla Fuster, Sergio Muñoz-Martínez, Carmen Ayuso, Jordi Rimola, Alejandro Forner, Alexandre Soler, Ferran Torres, José Ríos, Jordi Bruix, Andrew M. Moon, Xavier Forns, María Reig

“…Methods In this prospective, single-center study, HCV patients with advanced liver disease (F3/F4) treated and cured with DAA were invited to fill a lifestyle habits questionnaire in and perform abdominal ultrasound (US), blood extraction and anthropometric measurements within the 1st month after SVR and every 6 months thereafter until 48 months of follow-up, LC development, death, or loss to follow-up. Results This prospective cohort included 182 patients with SVR after DAA in this first analysis through the 4 years of follow-up. …”
Get full text

piR-26441 inhibits mitochondrial oxidative phosphorylation and tumorigenesis in ovarian cancer through m6A modification by interacting with YTHDC1 by Jing Yuan, Bu-Min Xie, Yu-Meng Ji, Hai-Juan Bao, Jie-Lin Wang, Jia-Chen Cheng, Xiang-Chun Huang, Yang Zhao, Shuo Chen

“…Furthermore, piR-26441 directly binds to and upregulates the expression of YTHDC1 in OC cells. piR-26441 also increased m6A levels, thereby interacting with YTHDC1 to destabilize the mRNA of TSFM. The resultant TSFM loss reduced mitochondrial complex I activity and mitochondrial OXPHOS, leading to mitochondrial dysfunction in OC cells, increased reactive oxygen species levels, and thus, DNA damage and apoptosis in OC cells, thereby inhibiting OC progression. …”
Get full text

Dysfunction of ATP7B Splicing Variant Caused by Enhanced Interaction With COMMD1 in Wilson DiseaseSummary by Donghu Zhou, Huaduan Zi, Xiaoxi Yang, Xiaojin Li, Yanmeng Li, Anjian Xu, Bei Zhang, Wei Zhang, Xiaojuan Ou, Jidong Jia, Jian Huang, Hong You

“…Results: The c.1543+1G>C mutation resulted in the skipping of ATP7B exon 3, and the mutant ATP7B showed a loss of trans-Golgi network localization and was degraded via the ubiquitin-proteasome pathway, facilitated by enhanced interactions with COMMD1. …”
Get full text

Acute Care Practice in the United States: The Roles of Occupational Therapy and Physical Therapy in Early Rehabilitation by Suzanne E. Holm, Kelly Nelson, Angela Patterson

“…The goals of OT and PT in an accelerated and fast-past hospital environment are to facilitate a patient's functional performance and outcomes to improve function recovery and to prevent further disability and loss of function. Currently in U. S., federal regulations, health care policies, financial constraints, and the demanded shortened hospital stays require therapists to be both comprehensive and efficient and to continue advancing ER practices. …”
Get full text

HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals by Elie Azoulay, Nancy Kentish Barnes, Sheila Nainan Myatra, Maria-Cruz Martin Delgado, Yaseen Arabi, Carole Boulanger, Giovanni Mistraletti, Maria Theodorakopoulou, Vernon Van Heerden, José-Artur Paiva, Oktay Demirkýran, Gabriel Heras La Calle, Abdulrahman Al Fares, Gaston Burghi, Guy Francois, Anita Barth, Jan De Waele, Samir Jaber, Michael Darmon, Maurizio Cecconi

“…Secondary outcomes include comparing the following between clusters: (1) number of HCPs with high emotional exhaustion; (2) number with high depersonalization; (3) number with loss of accomplishment; (4) perception of ethical climate (5) satisfaction at work (VAS); (6) professional conflicts; (7) intention to leave the ICU (VAS); (8) patient-centered care rating; (9) family-centered care rating. …”
Get full text

Analytical and Comparative Analysis of Copper Industry Development Programs in Iran by Adel Rouhi Jouybari, Seyed Mohammad Esmaiel Jalali

“…Sanctions have caused severe fluctuations in exchange rates and have affected the government's economic and trade policies, ultimately leading to increased production costs, market fluctuations, declining exports, loss of some export markets, rent-seeking, thriving intermediaries, and numerous problems in the field of financing and capital circulation of mining units and mining industries in the country. …”
Get full text

Association of glycemic control with Long COVID in patients with type 2 diabetes: findings from the National COVID Cohort Collaborative (N3C) by Jane E B Reusch, Rachel Wong, Nasia Safdar, Harold Lehmann, Brijesh Patel, Til Stürmer, Hongfang Liu, Peter Robinson, Elaine Hill, Richard Moffitt, Justin Guinney, Joel Gagnier, Cavin Ward-Caviness, Noha Sharafeldin, Justin Starren, Amit Saha, Lesley Cottrell, Melissa A Haendel, Margaret A Hall, Vignesh Subbian, Kristin Kostka, Farrukh M Koraishy, Andrew E Williams, Robert Hurley, Steve Johnson, Usman Sheikh, Rishi Kamaleswaran, Christopher Dillon, Michele Morris, Randeep Jawa, Hemalkumar Mehta, Benjamin Bates, Tellen D Bennett, Nabeel Qureshi, Katie Rebecca Bradwell, Federico Mariona, Adam B Wilcox, Adam M Lee, Alexis Graves, Amin Manna, Amy Olex, Andrea Zhou, Andrew Southerland, Andrew T Girvin, Anita Walden, Anjali A Sharathkumar, Benjamin Amor, Brian Hendricks, Caleb Alexander, Carolyn Bramante, Charisse Madlock-Brown, Christine Suver, Christopher Chute, Chunlei Wu, Clare Schmitt, Cliff Takemoto, Dan Housman, Davera Gabriel, David A Eichmann, Diego Mazzotti, Eilis Boudreau Don Brown, Elizabeth Zampino, Emily Carlson Marti, Emily R Pfaff, Evan French, Fred Prior, George Sokos, Greg Martin, Heidi Spratt, Hythem Sidky, JW Awori Hayanga, Jami Pincavitch, Jaylyn Clark, Jeremy Richard Harper, Jessica Islam, Jin Ge, Joel H Saltz, Joel Saltz, Johanna Loomba, John Buse, Jomol Mathew, Joni L Rutter, Julie A McMurry, Karen Crowley, Kellie M Walters, Ken Wilkins, Kenneth R Gersing, Kenrick Dwain Cato, Kimberly Murray, Lavance Northington, Lee Allan Pyles, Leonie Misquitta, Lili Portilla, Mariam Deacy, Mark M Bissell, Marshall Clark, Mary Emmett, Mary Morrison Saltz, Matvey B Palchuk, Meredith Adams, Meredith Temple-O'Connor, Michael G Kurilla, Nicole Garbarini, Ofer Sadan, Patricia A Francis, Penny Wung Burgoon, Rafael Fuentes, Rebecca Erwin-Cohen, Richard A Moffitt, Richard L Zhu, Robert T Miller, Saiju Pyarajan, Sam G Michael, Samuel Bozzette, Sandeep Mallipattu, Satyanarayana Vedula, Scott Chapman, T Shawn, Soko Setoguchi O'Neil, Stephanie S Hong, Tiffany Callahan, Umit Topaloglu, Valery Gordon, Warren A Kibbe, Wenndy Hernandez, Will Beasley, Will Cooper, William Hillegass, Xiaohan Tanner Zhang, Samuel Soff, Yun Jae Yoo, Jared Davis Huling, Daniel Brannock, Zachary Butzin-Dozier, Alfred Jerrod Anzalone, Philip RO. Payne, Rena Patel

“…Symptoms were identified as keywords from clinical notes using NLP in respiratory, brain fog, fatigue, loss of smell/taste, cough, cardiovascular and musculoskeletal symptom categories. …”
Get full text

Complete Genomic Landscape Reveals Hidden Evolutionary History and Selection Signature in Asian Water Buffaloes (Bubalus bubalis) by Jingfang Si, Dongmei Dai, Neena Amatya Gorkhali, Mingshan Wang, Sheng Wang, Saroj Sapkota, Ram Chandra Kadel, Amir Sadaula, Aashish Dhakal, Md Omar Faruque, Abdullah Ibne Omar, Eka Meutia Sari, Hidayat Ashari, Muhammad Ihsan Andi Dagong, Marnoch Yindee, Hossam E. Rushdi, Hussein Elregalaty, Ahmed Amin, Mohamed A. Radwan, Lan Doan Pham, W. M. M. P. Hulugalla, G. L. L. Pradeepa Silva, Wei Zheng, Shahid Mansoor, Muhammad Basil Ali, Farhad Vahidi, Sahar Ahmed Al‐Bayatti, Alfredo Pauciullo, Johannes A. Lenstra, J. Stuart F. Barker, Lingzhao Fang, Dong‐Dong Wu, Jianlin Han, Yi Zhang

“…Purifying selection prevented the accumulation of harmful loss‐of‐function variants in the Indonesian buffaloes. …”
Get full text

The Effect of Corona Dormancy on the Physiological Stress and Main Nutritional Components in the Transport of Trachinotus ovatus During Survival by Siwei LIU, Jiamei ZHONG, Xiuping FAN, Xiaoming QIN, Jian SHEN, Wenqi XU

“…However, the existing transportation of live fish suffers from various problems such as low survival rate, nutrient loss, and short transportation time due to stress, hypoxia, and water quality deterioration. …”
Get full text

Cow Hoof Slippage Detecting Method Based on Enhanced DeepLabCut Model by NIAN Yue, ZHAO Kaixuan, JI Jiangtao

“…Slippery grounds can lead to injuries in cows, resulting in unnecessary economic losses for farmers. To achieve automatically recognizing and detecting slippery hoof postures during walking, the study focuses on the localization and analysis of key body points of cows based on deep learning methods. …”
Get full text

Dual α-globin-truncated erythropoietin receptor knockin restores hemoglobin production in α-thalassemia-derived erythroid cells by Simon N. Chu, Eric Soupene, Devesh Sharma, Roshani Sinha, Travis McCreary, Britney Hernandez, Huifeng Shen, Beeke Wienert, Chance Bowman, Han Yin, Benjamin J. Lesch, Kun Jia, Kathleen A. Romero, Zachary Kostamo, Yankai Zhang, Tammy Tran, Marco Cordero, Shota Homma, Jessica P. Hampton, James M. Gardner, Bruce R. Conklin, Tippi C. MacKenzie, Vivien A. Sheehan, Matthew H. Porteus, M. Kyle Cromer

“…Summary: The most severe form of α-thalassemia results from loss of all four copies of α-globin. Postnatally, patients face challenges similar to β-thalassemia, including severe anemia and erythrotoxicity due to the imbalance of β-globin and α-globin chains. …”
Get full text

Benchmarking data-driven inversion methods for the estimation of local CO₂ emissions from synthetic satellite images of XCO₂ and NO₂ by D. Santaren, J. Hakkarainen, G. Kuhlmann, E. Koene, F. Chevallier, I. Ialongo, H. Lindqvist, J. Nurmela, J. Tamminen, L. Amorós, D. Brunner, G. Broquet

“…These ensembles are used to analyze the sensitivity of performance to (1) data loss due to cloud cover, (2) uncertainty in the wind, or (3) the added value of simultaneous NO<span class="inline-formula">₂</span> images. …”
Get full text

Effect of Sucrose Spray on some Phytochemical Characteristics of Stevia (Stevia rebaudiana Bertoni) under Field Conditions by Vahid Akbarpour, Hossein Aruei, Kambiz Mashayekhi, Majid Azizi Arani, Mohammad Ali Bahmanyar

“…An increase in the concentration of assimilated carbohydrates as a result of sucrose application at a concentration of 5% with the methanol solvent may increase the availability of respiratory intermediates, which results in the reduction of non-photochemical energy loss. The occurrence of these biochemical phenomena caused by the consumption of intermediate substances ultimately increases the photosynthetic efficiency and improves the accumulation of photosynthetic substances, as well as the synthesis of secondary metabolites. …”
Get full text

Credit Risk Management Practices and Loan Performance of Commercial Banks in Uganda. A Case Study of Commercial Banks in Mbarara City by Francis, Agaba

Get full text

Credit Risk Management Practices and Loan Performance of Commercial Banks in Uganda. A Case Study of Commercial Banks in Mbarara City by Agaba, Francis

“…This resulted to a significant loss of about Shs53.7bn in 2014 to Shs3.1bn in 2015 down from a net profit of Shs50.6bn in 2014 (Aine, 2018). …”
Get full text

Possible scenarios of sustainable supply chain in dairy industry with future research approach by Meysam Abedini, Narges Mohammadalipour, Ashraf Shahmansouri, Mahnaz Rabiei

“…On the other hand, it was determined that the foreign exchange rate and inflation have the greatest impact on other factors and the future of the dairy industry.Extended AbstractIntroductionMany companies suffer countless losses due to the lack of future-research strategy, which is apparently not possible to diagnose, but with the vision of future-research and its effect on the integration of the supply chain, it is possible to create value in the chain (Shafiee et al, 2020), and (Nirmala et al, 2021). …”
Get full text

Presenting the model of work and technology curriculum in secondary schools of Fars province by Hamzeh Rahpeyma, Seyedahmad Hashemi, Abbas Gholtash

Get full text

Designing a Future Study Model: Examining Bank Employees’ Attitudes Towards Job Security in the Era of Blockchain Technology (Horizon 2031) by Saeid Ghazi Nezhad, Hasan Darvish, Mohammad Mahmoudi Meymand

Get full text

Une cave à amphores, une statue en pierre et une tête coupée de la fin de l’âge du Fer à Châteaumeillant (Cher) by Sophie Krausz, Caroline Millereux, Marion Bouchet, Fabienne Olmer

“…Similarly, the cracking and darkening of the tooth enamel could be the result of being placed in an open-air setting. The loss of the canines and incisors is further indication of the possibility that the skull was exposed, possibly showcased in an elevated manner. …”
Get full text