A novel arterial coupler with non-return snap-fit connection approach optimized arterial end-to-end anastomotic technique: An experimental study by Hong-Bo Guo, Mo-Fei Wang, Ren-Qi Yin, Kang-Kang Zhi

“…The bilateral femoral arteries of 5 beagles were used for coupler-assisted anastomosis and hand-sewn anastomosis in vivo, respectively. Success rate, blood loss, anastomotic time, clamp time, total operation time, and patency rate were recorded. …”
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Assessment approach for conservation effectiveness and gaps for endangered species based on habitat suitability: A case study of alpine musk deer in western China by Feng Jiang, Pengfei Song, Jingjie Zhang, Dongwu Wang, Renhong Li, Chengbo Liang, Tongzuo Zhang

“…With the rapid socio-economic development, intensified land use and population growth have severely threatened global biodiversity, particularly on the Qinghai-Tibet Plateau, a global biodiversity hotspot where many endangered species face significant habitat loss and fragmentation. The alpine musk deer (Moschus chrysogaster), a species endemic to the Qinghai-Tibet Plateau and one of the most endangered species globally, requires critical habitat assessment and conservation efforts for regional and global biodiversity protection. …”
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CHANGES IN THE QUALITY OF LIFE AND SEXUAL FUNCTION IN WOMEN WITH PELVIC PROLAPSE AFTER LIGATION OF COLPOPEXY WITH POLYPROPYLENE MESH by A. D. Kaprin, A. A. Kostin, V. B. Filimonov, R. V. Vasin, I. V. Vasina

“…Vaginal reconstruction of pelvic prolapse using polypropylene implants in sexually active women leads to better sexual function by eliminating the loss of the walls of the vagina and urinary incontinence. …”
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Pathogenic PDE12 variants impair mitochondrial RNA processing causing neonatal mitochondrial disease by Lindsey Van Haute, Petra Páleníková, Jia Xin Tang, Pavel A Nash, Mariella T Simon, Angela Pyle, Monika Oláhová, Christopher A Powell, Pedro Rebelo-Guiomar, Alexander Stover, Michael Champion, Charulata Deshpande, Emma L Baple, Karen L Stals, Sian Ellard, Olivia Anselem, Clémence Molac, Giulia Petrilli, Laurence Loeuillet, Sarah Grotto, Tania Attie-Bitach, Jose E Abdenur, Robert W Taylor, Michal Minczuk

“…Our data suggest that PDE12 regulates mitochondrial RNA processing and its loss results in neurological and muscular phenotypes.…”
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In situ polymerized polyetherimide/Al2O3 nanocomposites with significantly improved capacitive energy storage performance at high temperatures by Li Tan, Jiufeng Dong, Li Li, Chengyuan Wang, Yuqi Liu, Yujuan Niu, Zizhao Pan, Liang Sun, Hong Wang

“…In contrast to the nanocomposites obtained by blending PEI polymers with AO, the in situ nanocomposites exhibit substantially improved filler dispersion, together with largely suppressed conduction loss at high fields and high temperatures, leading to comprehensive enhancements of breakdown strength (Eb), charge-discharge efficiency (η) and Ue, simultaneously. …”
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Genome-wide association mapping and genomic prediction analyses reveal the genetic architecture of grain yield and agronomic traits under drought and optimum conditions in maize by Manigben Kulai Amadu, Yoseph Beyene, Vijay Chaikam, Pangirayi B. Tongoona, Eric Y. Danquah, Beatrice E. Ifie, Juan Burgueno, Boddupalli M. Prasanna, Manje Gowda

“…Abstract Background Drought is a major abiotic stress in sub-Saharan Africa, impacting maize growth and development leading to severe yield loss. Drought tolerance is a complex trait regulated by multiple genes, making direct grain yield selection ineffective. …”
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Retrospective analysis of the occurrence, potential risk factors and medical significance of pulmonary complications after total shoulder arthroplasty from the National Inpatient S... by Mengning Dong, Huitong Liang, Jinlang Fu, Zeying Guo, Hao Xie, Qinfeng Yang, Qingmei Yu, Xiaomin Hou

“…The ailments at this period that were most likely to result in pulmonary problems were ulcer (adjusted odds ratio [AOR] = 9.43; 95% CI, 4.99–46.91), pulmonary circulation disorders (AOR = 9.01; 95% CI, 4.56– 31.92), weight loss (AOR = 4.84; 95% CI, 2.15–10.88), fluid and electrolyte disorders (AOR = 3.55; 95% CI, 2.55–4.95), alcohol abuse (AOR = 1.56; 95% CI, 1.08–2.26), congestive heart failure (AOR = 3.09; 95% CI, 1.83–5.24), chronic pulmonary disease (AOR = 2.45; 95% CI, 1.60–3.75), deficiency anaemia (AOR = 1.56; 95% CI, 1.08–2.26), depression (AOR = 1.47; 95% CI, 1.03–2.11) and obesity (AOR = 1.46; 95% CI, 1.01–2.11). …”
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Assessment of the southern polar and subpolar warming in the PMIP4 last interglacial simulations using paleoclimate data syntheses by Q. Gao, Q. Gao, Q. Gao, E. Capron, L. C. Sime, R. H. Rhodes, R. Sivankutty, X. Zhang, B. L. Otto-Bliesner, M. Werner

“…The hosed 128 ka HadCM3 simulation captures much of the warming and sea ice loss shown in the four data syntheses at 127 ka relative to preindustrial: south of 40° S, modeled annual sea surface temperature (SST) rises by 1.3 <span class="inline-formula">±</span> 0.6 °C, while reconstructed average anomalies range from 2.2 to 2.7 °C; modeled summer SST increases by 1.1 <span class="inline-formula">±</span> 0.7 °C, close to the 1.2–2.2 °C reconstructed average anomalies; September sea ice area (SIA) is reduced by 40 <span class="inline-formula"><i>%</i></span>, similar to the reconstructed 40 <span class="inline-formula">%</span> reduction of sea ice concentration (SIC); over the Antarctic Ice Sheet, modeled annual surface air temperature (SAT) increases by 2.6 <span class="inline-formula">±</span> 0.4 °C, even larger than reconstructed average anomalies of 2.2 °C. …”
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Prevalence and Molecular Characterization of Carbapenemase-Producing Multidrug-Resistant Bacteria in Diabetic Foot Ulcer Infections by Mohd Saleem, Soha Abdallah Moursi, Tahani Nasser Almofeed Altamimi, Mohammed Salem Alharbi, Alwaleed Mohammad Alaskar, Sahar Adly Hassan Hammam, Ehab Rakha, Ozair Ilyas Syed Muhammad, Hamoud Abdulmohsin Almalaq, Metab Nasser Alshammari, Azharuddin Sajid Syed Khaja

“…Carbapenemase-producing isolates presented high resistance to β-lactam antibiotics, whereas non-carbapenemase-producing isolates presented resistance through mechanisms such as porin loss and efflux pumps. <b>Conclusions:</b> The findings of this study highlight the significant burden of MDR infections, particularly carbapenemase-producing organisms, in DFUs. …”
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Identification of a transcription factor AoMsn2 of the Hog1 signaling pathway contributes to fungal growth, development and pathogenicity in Arthrobotrys oligospora by Qianqian Liu, Kexin Jiang, Shipeng Duan, Na Zhao, Yanmei Shen, Lirong Zhu, Ke-Qin Zhang, Jinkui Yang

“…Methods: The function of AoMsn2 was characterized using targeted gene deletion, phenotypic experiments, real-time quantitative PCR, RNA sequencing, untargeted metabolomics, and yeast two-hybrid analysis. Results: Loss of Aomsn2 significantly enlarged and swollen the hyphae, with an increase in septa and a significant decrease in nuclei. …”
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Comparative Analysis of Biochemical Parameters, Thermal Behavior, Rheological Features, and Gelling Characteristics of Thai Ligor Hybrid Chicken and Broiler Meats by Ngassa Julius Mussa, Chantira Wongnen, Warangkana Kitpipit, Worawan Panpipat, Mingyu Yin, Siriporn Riebroy Kim, Manat Chaijan

“…LC meat showed higher storage modulus (G′) and loss modulus (G″) values than BC meat, suggesting a stronger gel-forming tendency. …”
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Real world pharmacovigilance assessment of drug related macular degeneration risks by Xiaodong Chen, Shinan Wu, Shaopan Wang, Chaofeng Yu, Zihan Guo, Shiya Huang, Peixin Cai, Yanliang Miao, Shiying Li, Qian Chen

“…Abstract Macular degeneration is a leading cause of irreversible vision loss, significantly impacting quality of life. To enhance clinical practice and reduce the risk of drug-related macular degeneration, we analyzed drug-related trends using real-world data. …”
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<i>Eugenia uniflora</i> Effects on the Depressive-like Behavior of MPTP-Exposed Female Rats: Apoptosis and α-Synuclein Modulation by Anne Suély Pinto Savall, Jhuly Dorneles De Mello, Eduarda Monteiro Fidelis, Vandreza Cardoso Bortolotto, Mustafa Munir Mustafa Dahleh, Gustavo Petri Guerra, Marina Prigol, Robson Puntel, Jean Ramos Boldori, Cristiane Casagrande Denardin, Tuane Bazanella Sampaio, Simone Pinton

“…<b>Background:</b> Parkinson’s disease (PD) is a neurodegenerative disorder marked by motor deficits and non-motor symptoms, such as depression, which are associated with dopaminergic loss and α-synuclein aggregation in the brain. <b>Objectives:</b> This study investigated the neuroprotective effects of a hydroalcoholic extract of the purple fruit of <i>Eugenia uniflora</i> (PFEU) on motor ability and depressive-like behaviors in a PD model induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in female Wistar rats. …”
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Intradiscal Injection of Induced Pluripotent Stem Cell-Derived Nucleus Pulposus-Like Cell-Seeded Polymeric Microspheres Promotes Rat Disc Regeneration by Kaishun Xia, Jian Zhu, Jianming Hua, Zhe Gong, Chao Yu, Xiaopeng Zhou, Jingkai Wang, Xianpeng Huang, Wei Yu, Liming Li, Jianqing Gao, Qixin Chen, Fangcai Li, Chengzhen Liang

“…Cell replacement therapy is an attractive alternative for treating degenerated intervertebral discs (IVDs), which are related to the reduction of nucleus pulposus-like cells (NP-lCs) and the loss of the extracellular matrix. Induced pluripotent stem cells (iPSCs) which resemble embryonic stem cells are considered to be a potential resource for restoring NP-lCs and disc homeostasis. …”
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Chromosomal Abnormalities in Miscarriages and Maternal Age: New Insights from the Study of 7118 Cases by Anna A. Pendina, Mikhail I. Krapivin, Olga G. Chiryaeva, Lubov’ I. Petrova, Elizaveta P. Pashkova, Arina V. Golubeva, Andrei V. Tikhonov, Alla S. Koltsova, Ekaterina D. Trusova, Dmitrii A. Staroverov, Andrey S. Glotov, Olesya N. Bespalova, Olga A. Efimova

“…Chromosomal abnormalities of the embryo are the most common cause of first-trimester pregnancy loss. In this single-center study, we assessed the frequency and the spectrum of chromosomal abnormalities in miscarriages for each year of maternal age from 23 to 44. …”
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Circumscribed choroidal hemangioma: clinical course and treatment by A.F. Brovkina, A.S. Stoyukhina, I.V. Musatkina

“…</i> </p> <p> <i><b>Conclusion</b>: CCH is a torpid benign choroidal tumor with good vision at baseline which requires dynamic follow-up and OCT to monitor retina, retinal detachment height, and tumor thickness. Progressive loss of vision and progressive retinal detachment are considered indications for treatment. …”
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Intramural pregnancy after intrauterine insemination in a nulligravid patient without previous uterine trauma, complicated by idiopathic thrombocytopenic purpura: A case report by Koyo Yamamoto, Tsuyoshi Takiuchi, Kengo Kiso, Saki Ishii, Satoshi Nakagawa, Yasuto Kinose, Michiko Kodama, Yutaka Ueda, Kenjiro Sawada, Takahiro Tsuboyama, Tadashi Kimura

“…The gestational sac covered with the uterine serosa was dissected, and the uterine defect was repaired to preserve fertility. The blood loss was 320 mL. The patient's postoperative recovery was uneventful, and histopathological examination confirmed the diagnosis of IMP. …”
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Improving wear and corrosion resistances of Mg2Si/AZ91 composites via tailoring microstructure and intrinsic properties of Mg2Si induced by Sb modification by Peng Xiao, Yimin Gao, Yupeng Sheng, Cuicui Yang, Zhiwei Liu, Yanliang Yi, Wenyu Wu, Qiqiang Zhao, Manoj Gupta

“…Sb modified composite exhibits a 26% lower wear loss than unmodified composite, suggesting the greatly improved wear resistance. …”
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Extraction of American ginseng polysaccharide by ultrasound-assisted deep eutectic solvents-based three-phase partitioning: Process optimization, structural characterization, and a... by Zhongnan Wu, Chong Li, Junhao Li, Tanggan Wang, Meifeng Li, Leyi Zhao, Huimei Ye, Jiaheng Chen, Jiajia Zan, Lijun Song, Qian Zhang, Shaojie Zhang

“…The optimized DES-4, composed of lauric acid and nonanoic acid (molar ratio = 1:1), achieved a 35.28 % extraction yield under specific conditions and can be recycled five times with minimal yield loss. AGP-DES-4 has a broad molecular weight distribution (2.48–174.64 kDa) and mainly consists of mannose, glucose, galactose, and arabinose. …”
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The development and application of compound formulation of natural antioxidants in Idesia polycarpa maxim. Oil by Fangming Liu, Yurui Xie, Xiaodong Geng, Zhi Li, Yanmei Wang, Zhen Liu, Qifei Cai

“…The results showed that the antioxidant capacity of the compound formulation was significantly increased, and the generation of secondary oxidation products was inhibited and the loss of unsaturated fatty acids was reduced. Therefore, the compound antioxidant-added Idesia polycarpa Maxim. oil not only showed good storage resistance, but also improved the safety of use under high temperature environment. …”
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