Systemic Resolvin E1 (RvE1) Treatment Does Not Ameliorate the Severity of Collagen-Induced Arthritis (CIA) in Mice: A Randomized, Prospective, and Controlled Proof of Concept Study by Rafael Scaf de Molon, Rogier M. Thurlings, Birgitte Walgreen, Monique M. Helsen, Peter M. van der Kraan, Joni Augusto Cirelli, Marije I. Koenders

“…CIA triggered significant inflammation in the synovial cavity, proteoglycan loss, and cartilage and bone destruction in the ankle joints of mice. …”
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Temporal variations in the ice volume of Xiao Dongkemadi Glacier, central Tibetan Plateau, from 1969 to 2020 by An’an Chen, Ninglian Wang, Zhen Li, Yuwei Wu, Xi Jiang, Zhongming Guo, Xuejiao Wu, Xuewen Yang

“…The long-term mass-balance reconstruction reveals weak fluctuations occurred from 1967 to 1993 and that overall mass losses have occurred since 1994. This ongoing shrinkage and ice loss are mainly associated with the temperature increases in the warm season since the 1960s. …”
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TPDTNet: Two-Phase Distillation Training for Visible-to-Infrared Unsupervised Domain Adaptive Object Detection by Siyu Wang, Xiaogang Yang, Ruitao Lu, Shuang Su, Bin Tang, Tao Zhang, Zhengjie Zhu

“…This convolutional operation is embedded following standard convolution to mitigate the loss of detailed features. Finally, a distillation training strategy that utilizes pseudodetection labels to calculate target information. …”
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Effect of Tremella fuciformis polysaccharide on the stalling and flavor of tteok during storage by Hongxiu Fan, Hongcheng Liu, Wenyi Li, Wenjing Su, Dawei Wang, Shanshan Zhang, Tingting Liu, Yanrong Zhang

“…Overall, this study could help food manufacturers to choose a high-effective and natural polysaccharide to control the retrogradation rate and flavor loss of tteok.…”
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Photothermal performance of nanofluids: An experimental study on direct absorption solar energy conversion using graphene oxide and its binary composites for water purification by Abdul Sattar, Bai Bofeng, M. Adeel Munir, Muhammad Farooq, S. Bilal, M. Imran Khan, Noreen Sher Akbar, Mohammed Ilyas Khan, Mohammad Rehan, Fahid Riaz

“…For this purpose a direct absorption solar collector set-up was constructed to measure evaporation rate under natural solar light, a pyranometer to measure light intensity, a K-thermocouple system to measure temperature and digital balance to measure mass loss. Then, nanofluids were prepared using a standard two-step method, and characterized using scanning electron microscopy and ultraviolet–visible spectroscopy. …”
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Ophthalmologists’ and patients’ perspectives on treatments for diabetic retinopathy and maculopathy in Vietnam: a descriptive qualitative study by Tunde Peto, Nathan Congdon, Lynne Lohfeld, Hoang Tran, Katie Curran, Van Thu Nguyen, Tung Thanh Hoang, Hue Thi Nguyen, Quan Nhu Nguyen, Catherine Dardis, Hoang Huy Tran, Anh Tuan Vu, Mai Quoc Tung

“…Early detection and treatment of DR is essential for preventing sight loss. Services must be available, accessible and acceptable to patients if we are to ensure they seek such care.Objectives To understand patients’ knowledge and attitudes towards laser versus antivascular endothelial growth factor (VEGF) injections to treat DR in Vietnam, and to identify factors Vietnamese ophthalmologists consider when making treatment decisions.Methods This is a descriptive qualitative study based on semi-structured interviews with 18 patients (12 from Ho Chi Minh City and 6 from Hanoi) plus individual interviews with 24 ophthalmologists working in eye clinics in these cities. …”
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Healthy aging in frail older adults: Active aging project of a national survey by Jisu Seo, Kyungok Joo, Yuelin Li, Nayoung Kim, Eunna Oh, Lkhagvajav Gansukh, Rhayun Song

“…Due to their vulnerability and reduced physiological reserves, frail older adults face an increased risk of functional decline and loss of independence. In frail older adults, the concept of healthy aging emphasizes maintaining independence, functionality, and a high quality of life despite frailty and other age-related challenges. …”
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Detecting gene copy number alterations by Oncomine Comprehensive genomic profiling in a comparative study on FFPE tumor samples by Fabio Bozzi, Elena Conca, Marco Silvestri, Gianpaolo Dagrada, Alice Ardore, Donata Penso, Daniele Lorenzini, Chiara Costanza Volpi, Desirè Viola Trupia, Adele Busico, Iolanda Capone, Federica Perrone, Elena Tamborini, Andrea Vingiani, Luca Agnelli, Giancarlo Pruneri

“…No significant threshold maximizing the difference between true and false positive losses was found. Orthogonal FISH tests validated seven CNAs characterized by CN gain ≥ 6 or complete loss. …”
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Effects of Nicotinamide Riboside Supplementation on Postmortem Mitochondrial Functionality and Apoptotic Activation by Chen Zhu, Luke A. Whitcomb, Adam J. Chicco, Morgan E. Gravely, Hanna M. Alcocer, Daniela A. Alambarrio, John M. Gonzalez, Colton L. Smith, Mahesh N. Nair, Huey Yi Loh, Terry E. Engle, Arya Niraula, Chaoyu Zhai

“…Results: NR-supplemented muscle exhibited lower proton leak-associated respiration at 45 min postmortem (<i>p</i> < 0.05), followed by a slower accumulation of mitochondrial outer membrane permeabilization (MOMP; <i>p</i> < 0.05) and a slower loss of mitochondrial integral function (<i>p</i> < 0.05) from 45 min to 24 h postmortem. …”
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L’aqueduc de Fontanières : un cinquième aqueduc romain à Lyon ? by Jean-Yves Barbier

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Alimenter la ville de Lyon en eau : les galeries de captage antiques sous les collines de Fourvière et de la Croix-Rousse by Emmanuel Bernot

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Reduced interhemispheric connectivity in traumatic brachial plexopathies after bionic reconstruction by Galia V Anguelova, Agnes Sturma, Oskar Aszmann, Mehmet S Yildirim, Anna Boesendorfer, Victor Schmidbauer, Karl-Heinz Nenning, Gregor Kasprian

“…Patients without prosthesis also exhibited fewer structural connections between the left and right thalamus and pallidum, whereas those with prosthesis demonstrated increased structural connectivity compared to controls.The increased and more widespread cortical activity and functional connectivity after TBPL may be due to increased central effort necessary for motor execution and planning, representing a compensation mechanism for the decrease of interhemispheric and subcortical connectivity. The initial loss of white matter may be counteracted by increased function and grey matter recruitment, which seems necessary even after white matter recovery later with prosthesis use. …”
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Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure by Sophie Shen, Tessa Werner, Samuel W. Lukowski, Stacey Andersen, Yuliangzi Sun, Woo Jun Shim, Dalia Mizikovsky, Sakurako Kobayashi, Jennifer Outhwaite, Han Sheng Chiu, Xiaoli Chen, Gavin Chapman, Ella M. M. A. Martin, Di Xia, Duy Pham, Zezhuo Su, Daniel Kim, Pengyi Yang, Men Chee Tan, Enakshi Sinniah, Qiongyi Zhao, Sumedha Negi, Meredith A. Redd, Joseph E. Powell, Sally L. Dunwoodie, Patrick P. L. Tam, Mikael Bodén, Joshua W. K. Ho, Quan Nguyen, Nathan J. Palpant

“…Interrogation of temporal and signalling-specific gene expression in this atlas, evaluated against cell type-specific gene expression in human complex trait data highlights the WNT-inhibitor gene TMEM88 as a regulator of mesendodermal lineages influencing cardiovascular and anthropometric traits. Genetic TMEM88 loss of function models show impaired differentiation of endodermal and mesodermal derivatives in vitro and dysregulated arterial blood pressure in vivo. …”
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Comparison of Robot-Assisted, Laparoscopic, and Open Radical Prostatectomy Outcomes: A Systematic Review and Network Meta-Analysis from KSER Update Series by Do Kyung Kim, Young Joon Moon, Doo Yong Chung, Hae Do Jung, Seung Hyun Jeon, Seok Ho Kang, Sunghyun Paick, Joo Yong Lee

“…There was no difference in the estimated blood loss or the total and major complication rates between RARP, ORP, and LRP. …”
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Driving effect of P16 methylation on telomerase reverse transcriptase-mediated immortalization and transformation of normal human fibroblasts by Xuehong Zhang, Paiyun Li, Ying Gan, Shengyan Xiang, Liankun Gu, Jing Zhou, Xiaorui Zhou, Peihuang Wu, Baozhen Zhang, Dajun Deng, Jing Ni

“…Notably, cell immortalization, loss of contact inhibition, and anchorage-independent growth were always prevalent in P16-Dnmt&TERT cells, indicating cell transformation. …”
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Water triggered injectable polylactic acid hydrogel based on zwitterionic sulfobetaine modification for incompressible bleeding and tissue anti-adhesion by Xinran Yang, Xiudan Wang, Lizong Tang, Zhiguang Sun, Xing Gao, Yanmei Zhao, Shike Hou, Jie Shi, Qi Lv

“…Massive blood loss is the main cause of prehospital trauma-related death, the development of rapid and effective hemostatic materials is imminent. …”
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Comparison of the safety of esophagojejunal overlap and π-shaped anastomosis in totally laparoscopic total gastrectomy by Tongkun Song, Maoxing Liu, Kai Xu, Jiadi Xing, Kechen Guo, Xinyu Qi, Pin Gao, Fei Tan, Zhendan Yao, Nan Zhang, Hong Yang, Chenghai Zhang, Ming Cui, Xiangqian Su

“…No significant difference was found in the operation time, intraoperative blood loss, and postoperative hospital stay between the two anastomosis methods (p > 0.05); however, the π-shaped anastomosis group had more postoperative anastomotic leakage (p < 0.05). …”
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Experimental Validation of Antiobesogenic and Osteoprotective Efficacy of Ginsenoside CK via Targeting Lipid and Atherosclerosis Pathways by Md. Niaj Morshed, Reshmi Akter, Imran Mahmud, Ah-Yeong Gwon, Jin Woo Jeang, Yeong-Geun Lee, Dae Won Park, Deok Chun Yang, Yeon Ju Kim, Se-Chan Kang

“…These encouraging results demonstrate the possible use of CK as an innovative treatment for controlling obesity and osteoporosis, targeting the underlying mechanisms of obesogenic and bone loss. Further studies are necessary to explore the clinical implications of these results and the potential of CK in future treatment strategies. …”
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Influence of network latency and bandwidth on robot-assisted laparoscopic telesurgery: A pre-clinical experiment by Ye Wang, Qing Ai, Taoping Shi, Yu Gao, Bin Jiang, Wuyi Zhao, Chengjun Jiang, Guojun Liu, Lifeng Zhang, Huaikang Li, Fan Gao, Xin Ma, Hongzhao Li, Xu Zhang, Yuanyuan Ji

“…Network latency, jitter, frame loss, and bit rate code were systemically measured during these operations. …”
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Diagnostics and Treatment of Esophageal Achalasia (Clinical Guidelines of the Russian Gastroenterological Association, Russian Scientific Medical Society of Internal Medicine, Russ... by V. T. Ivashkin, A. S. Trukhmanov, I. V. Maev, O. M. Drapkina, A. I. Martynov, O. A. Storonova, E. A. Godgello, M. P. Korolev, T. L. Lapina, P. V. Pavlov, A. V. Paraskevova, I. A. Tarasova, E. D. Fedorov, A. T. Tskhovrebov, M. P. Shapka, A. L. Shestakov, A. V. Yurasov

“…However, it is believed that the key role belongs to the changes in the myenteric (Auerbach’s) intermuscular plexus of the enteric nervous system of the esophagus, leading to loss of neuronal function. The following hypotheses have been proposed as the main mechanisms for the development of achalasia: genetic predisposition, exposure to viral infections, and idiopathic autoimmune triggers. …”
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