Identification of determinants that allow maintenance of high-level fluoroquinolone resistance in Acinetobacter baumannii by Efrat Hamami, Wenwen Huo, Juan Hernandez-Bird, Arnold Castaneda, Jinna Bai, Sapna Syal, Juan C. Ortiz-Marquez, Tim van Opijnen, Edward Geisinger, Ralph R. Isberg

“…In contrast, AdeAB pump hyperexpression, in the absence of elevated adeC expression (the outer membrane component of the pump), was relatively tolerant to loss of these functions, consistent with the outer membrane protein being the primary disruptive component. …”
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Double degree programs and education for sustainable development implementation: Experience of Ukrainian and UK universities cooperation in wartime by Iryna Skliar, Mykola Kostel’, Olena Melnyk, Kseniia Bliumska-Danko

“…Ukrainian HEIs have been significantly losing their capacity for development. Loss of human capital, including educational losses, becomes more relevant from the perspective of further sector development.This paper explores the intersection of DDP implementation and the implementation of Education for Sustainable Development (ESD), focusing on faculty members’ experiences within the Twinning Initiative framework. …”
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Combination of Compound Kushen injection with first-line treatment versus first-line treatment alone for advanced colorectal cancer: a study protocol for a multicenter, openlabel,... by Jingyuan Wu, Yuansha Ge, Guanghui Zhu, Ruike Gao, Xiaoyu Zhu, Ying Zhang, Jie Li

“…Follow-up will occur every 3 months until death or loss to follow-up. The primary outcome of this study will be progression-free survival (PFS). …”
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Approach to shoulder instability: a randomized, controlled trial by Julien Caron, MD FRCSC, Kellen Walsh, MD FRCSC, Tinghua Zhang, MSc, Rashed AlAhmed, MBChB MSc FRCSC, Peter B. MacDonald, MD FRCSC, Cristina Bassi, MD, J Whitcomb Pollock, MD FRCSC MSc, Katie McIlquham, BSc, Peter Lapner, MD FRCSC

“…Patients randomized to the CTA group underwent a Latarjet procedure if the glenoid bone loss was > 25%. The primary outcome was the Western Ontario Shoulder Instability Index. …”
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Risk factors for the ineffectiveness of assisted reproductive technology programs after a woman’s illness with COVID-19 by O.G. Boichuk, I.S. Golovchak

“…In the group of 80 examined patients with symptoms of “long-COVID” who applied to the reproductive technology clinic for infertility treatment, 2 subgroups were distinguished: the Subgroup 1: 64 patients in whom assisted reproductive technologies (ART) was unsuccessful (cancellation of transfer, non-occurrence of pregnancy or its loss) and the Subgroup 2: 16 women with successful ART (live birth). …”
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Fine-scale satellite-based monitoring of temperature and vegetation cover in microclimates, distribution ranges, and landscape connectivity for Neurergus kaiseri (Kaiser’s mountain... by Peyman Karami, Sajad Tavakoli, Mina Esmaeili

“…Decreases in ZMKNDVI along linkages indicated water presence, whereas increases in ZMKLST were due to water loss and exposed riverbeds.By integrating fine-scale habitat suitability and connectivity findings with detailed, time-specific SRS indicators, we create a comprehensive environmental monitoring strategy. …”
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A multi-modal multi-branch framework for retinal vessel segmentation using ultra-widefield fundus photographs by Qihang Xie, Qihang Xie, Xuefei Li, Yuanyuan Li, Yuanyuan Li, Jiayi Lu, Jiayi Lu, Shaodong Ma, Yitian Zhao, Yitian Zhao, Jiong Zhang, Jiong Zhang

“…To further address the challenges of high-resolution UWF fundus images, we introduce a Local Perception Fusion Module (LPFM) to mitigate context loss during the segmentation cut-patch process. Complementing this, the Attention-Guided Upsampling Module (AUM) enhances segmentation performance through convolution operations guided by attention mechanisms.ResultsExtensive experimental evaluations demonstrate that our approach significantly outperforms existing state-of-the-art methods for UWF fundus image segmentation.…”
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Neuropsychiatric manifestations following chimeric antigen receptor T cell therapy for cancer: a systematic review of clinical outcomes and management strategies by Max Topp, Michael Hudecek, Hermann Einsele, Imad Maatouk, Leo Rasche, Johannes Duell, Anna Fleischer, Sophia Kurth, Patrick-Pascal Strunz, Julia Mersi, Carmen Sanges

“…Among the most frequently reported neuropsychological symptoms were aphasia, attention deficits, impaired consciousness, and disorientation, alongside a constellation of other symptoms including confusion, cognitive impairment, memory loss, writing difficulties, fatigue, headache, agitation, tremor, seizures, and psychomotor retardation. …”
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Macroecological predictors to determine future refuges of Luciobarbus species in the Tigris–Euphrates basin: Rethinking conservation strategies and management by Hadi Khoshnamvand, Seyed Mohsen Mousavi, Asef Darvishi, Kourosh Ahmadi, Amir Naghibi, Karel Janko, Asghar Abdoli, Faraham Ahmadzadeh

“…We employed a generalized linear model (GLM) with a quasi-Poisson distribution to create a map depicting the richness of Luciobarbus fish species.Our projections indicate that suitable habitats will decline in both time series under climate change SSP126 and SSP585 scenarios, resulting in the loss of certain habitat patches in the Southwest of Iran, Syria and Iraq. …”
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Analysis of Acoustic Surface Wave Focused Unidirectional Interdigital Transducers Using Coupling-of-Mode Theory by Guopeng Hui, Tinglun Ao, Haotian Liu, Minglei Li, Chen Chen

“…The EWC-FEFUDT (Design 3) has a lower insertion loss (IL) of −5.1 dB and greater unidirectionality (20 × log₁₀(<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>D</mi></mrow></semantics></math></inline-formula>) = 13.8 dB). …”
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Athermal Tantalum Pentoxide Mach-Zehnder Interferometers Based on Structural Compensation Method by Mingjian You, Zhenyu Liu, Weiren Cheng, Xingyu Tang, Ning Ding, Zhengqi Li, Min Wang, Li Shen, Qiancheng Zhao

“…This work proves the effectiveness of structural compensation method on an already low thermo-optic photonic platform, paving the way towards realization of ultra-athermal integrated optical filters in a low-loss and CMOS-compatible platform.…”
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Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction by Jingrun Lin, Xiaoqiu Zhu, Xuan Li, Yu Hong, Yaohui Liang, Siqi Chen, Chenzhuo Feng, Lin Cao

“…Abstract Background Postoperative cognitive dysfunction (POCD) represents a post-surgical complication that features progressive cognitive impairment and memory loss, often occurring in elderly patients. This study aimed to investigate the potential biological mechanisms underlying POCD. …”
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Could Metabolic Syndrome, Lipodystrophy, and Aging Be Mesenchymal Stem Cell Exhaustion Syndromes? by Eduardo Mansilla, Vanina Díaz Aquino, Daniel Zambón, Gustavo Horacio Marin, Karina Mártire, Gustavo Roque, Thomas Ichim, Neil H. Riordan, Amit Patel, Flavio Sturla, Gustavo Larsen, Rubén Spretz, Luis Núñez, Carlos Soratti, Ricardo Ibar, Michiel van Leeuwen, José María Tau, Hugo Drago, Alberto Maceira

“…The main outcome of this SCES would be an irreversible loss of the effective regenerative mesenchymal stem cells (MSCs) pools. …”
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Deep Lateral Wall Partial Rim-Sparing Orbital Decompression with Ultrasonic Bone Removal for Treatment of Thyroid-Related Orbitopathy by Álvaro Bengoa-González, Alicia Galindo-Ferreiro, Enrique Mencía-Gutiérrez, Hortensia Sánchez-Tocino, Agustín Martín-Clavijo, María-Dolores Lago-Llinás

“…We noted no surgical complications such as ocular or soft tissue damage, infection, inflammation, or visual loss. Conclusions. The SONOPET® ultrasonic bone curette can be used safely and effectively for DLW orbital decompression surgery. …”
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METTL3-Mediated m6A Modification Regulates the Osteogenic Differentiation through LncRNA CUTALP in Periodontal Mesenchymal Stem Cells of Periodontitis Patients by Xin Chen, Yuan Qin, Xian Wang, Hao Lei, Xiaochen Zhang, Houzhuo Luo, Changgang Guo, Weifu Sun, Shishu Fang, Wen Qin, Zuolin Jin

“…Periodontitis is a chronic inflammatory disease that causes loss of periodontal support tissue. Our objective was to investigate the mechanism by which METTL3-mediated N6-methyladenosine modification regulates the osteogenic differentiation through lncRNA in periodontal mesenchymal stem cells in patients with periodontitis (pPDLSCs). …”
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Totally robotic total gastrectomy with D2 lymphadenectomy for gastric cancer via da Vinci Xi platform: Technical details and perioperative outcomes by Chengcai Liang, Jianrong Guo, Guoming Chen, Zhiwei Zhou, Shuqiang Yuan

“…Results: With an estimated blood loss of 100 ​ml, the operation lasted 210 ​min, including an anastomosis time of 36 ​min. …”
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Oral lesions and disorders and their prevalence arising from the use of illicit drugs in a prison population. by Marta Relvas, Luciana Rocha, Paulo Rompante, Filomena Salazar, Luís Monteiro, Ana Sofia Vinhas, Maria Gonçalves

“…Conclusion: The main oral manifestations found, associated to the consumption of illicit drugs were caries lesions, tooth loss and sensitivity, periodontal diseases, temporomandibular disorders, xerostomia, and bruxism. …”
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Long-term neuropsychologic outcome of pre-emptive mTOR inhibitor treatment in children with tuberous sclerosis complex (TSC) under 4 months of age (PROTECT), a two-arm, randomized,... by Jan H. Driedger, Julian Schröter, PROTECT-Study Group, Steffen Syrbe, Afshin Saffari

“…On the molecular level, TSC is caused by heterozygous loss-of-function variants in either of the genes TSC1 or TSC2, encoding the Tuberin-Hamartin complex, which acts as a critical upstream suppressor of the mammalian target of rapamycin (mTOR), a key signaling pathway controlling cellular growth and metabolism. …”
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Gut dysbiosis-induced vitamin B6 metabolic disorder contributes to chronic stress-related abnormal behaviors in a cortisol-independent manner by Wenxiang Qing, Huimin Chen, Xin Ma, Jie Chen, Yuan Le, Hui Chen, Jianhua Tong, Kaiming Duan, Daqing Ma, Wen Ouyang, Jianbin Tong

“…Vitamin B6 supplement during RRS alleviated weight loss, abnormal behaviors, peripheral inflammation, and neuroinflammation, but did not affect the peripheral corticosterone levels in chronic stressed rats. …”
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Systemic hypotension and low perfusion pressure as risk factors for primary open-angle glaucoma progression by O.S. Myakonkaya, A.S. Sarkisyan, A.V. Seleznev, A.V. Kuroyedov, A.Yu. Brezhnev

“…However, many patients with primary open-angle glaucoma (POAG) continue to suffer vision loss despite IOP reduction. Additional factors are also important for glaucoma progression, e.g., blood pressure (BP) and ocular perfusion pressure (OPP). …”
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