Metabolic adaptations to acute glucose uptake inhibition converge upon mitochondrial respiration for leukemia cell survival by Monika Komza, Jesminara Khatun, Jesse D. Gelles, Andrew P. Trotta, Ioana Abraham-Enachescu, Juan Henao, Ahmed Elsaadi, Andriana G. Kotini, Cara Clementelli, JoAnn Arandela, Sebastian El Ghaity-Beckley, Agneesh Barua, Yiyang Chen, Mirela Berisa, Bridget K. Marcellino, Eirini P. Papapetrou, Masha V. Poyurovsky, Jerry Edward Chipuk

“…Despite significant pre-clinical effort to exploit this pathway, additional mechanistic insights are necessary to prioritize the diversity of metabolic adaptations upon acute loss of glucose metabolism. Here, we investigated a potent small molecule inhibitor to Class I glucose transporters, KL-11743, using glycolytic leukemia cell lines and patient-based model systems. …”
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The assessment of marrow adiposity in type 1 diabetic rabbits through magnetic resonance spectroscopy is linked to bone resorption by Wei Li, Wei Wang, Minlan Zhang, Qi Chen, Fengyi Li, Shaojun Li

“…The underlying mechanisms responsible for bone loss in diabetes are not well understood. In this investigation, we employed an alloxan-induced diabetes rabbit model to unravel the association between marrow fat content and bone resorption, utilizing magnetic resonance spectroscopy.MethodsForty 4-month-old male New Zealand rabbits were randomly allocated into two groups: a control group and an alloxan-induced diabetic group, each consisting of 20 rabbits. …”
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Plant Disease Classifier: Detection of Dual-Crop Diseases Using Lightweight 2D CNN Architecture by Hasibul Islam Peyal, Md. Nahiduzzaman, Md. Abu Hanif Pramanik, Md. Khalid Syfullah, Saleh Mohammed Shahriar, Abida Sultana, Mominul Ahsan, Julfikar Haider, Amith Khandakar, Muhammad E. H. Chowdhury

“…However, many diseases reduce the quality and quantity of tomato and cotton crops, resulting in a significant loss in production and productivity. It is critical to detect these disorders at an early stage of diagnosis. …”
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A Space Efficient Circular Patch MIMO Antenna Having Six Degrees of Freedom for 5G-n79/WLAN Applications by Susanta Kumar Badi, Om Prakash Acharya, Bhargav Appasani, Nicu Bizon

“…In addition, channel capacity loss and total active reflection coefficient are studied for multiport MIMO antenna system and found within acceptable limit.…”
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Characteristics of Soil Active Carbon Fractions and Carbon Pool Stability in Major Forest Types in Northern Daxing’an Mountains by LIU Beibei, CAI Tijiu

“…The overall stability of soil organic carbon in coniferous forests in the cold temperate zone was greater than that in broad-leaved forests, but the rate of organic carbon loss from deeper soil layers in coniferous forests was higher than that in broad-leaved forests under higher temperatures. …”
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Relating Sensory, Cognitive, and Neural Factors to Older Persons’ Perceptions about Happiness: An Exploratory Study by Alexandra J. Horne, Kimberly S. Chiew, Jie Zhuang, Linda K. George, R. Alison Adcock, Guy G. Potter, Eleonora M. Lad, Scott W. Cousins, Frank R. Lin, Sara K. Mamo, Nan-Kuei Chen, Abigail J. Maciejewski, Xuan Duong Fernandez, Heather E. Whitson

“…Despite increased rates of disease, disability, and social losses with aging, seniors consistently report higher levels of subjective well-being (SWB), a construct closely related to happiness, than younger adults. …”
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Optic nerve sheath diameter in chronic myeloproliferative disorders by E.M. Yunusova, T.R. Mukhamadeev, B.A. Bakirov

“…For patients with chronic MPD, it is recommended to have more detailed follow-up to prevent vision loss and life-threatening complications in the central nervous system due to disease progression, in particular, those with an increase in ONSD. …”
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Deficiency of purinergic P2Y2 receptor impairs the recovery after renal ischemia-reperfusion injury and accelerates renal fibrosis and tubular senescence in mice by Kyuho Jeong, Jihyun Je, Theodomir Dusabimana, Jacques Karekezi, Tatang Aldi Nugroho, Edvard Ntambara Ndahigwa, Hyun Joon Kim, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park

“…Abstract Chronic kidney disease is defined as a progressive loss of kidney function associated with impaired recovery after acute kidney injury. …”
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Feasibility study of pilot scale vegetable waste composting project for Kundasang community’s waste management program by Noorafizah Murshid, Abu Zahrim Yaser, Junidah Lamaming, Mariani Rajin, Sariah Saalah, Mariana Taliban

“…Method: The composting performance (temperature, organic matter loss, moisture content, pH value, electrical conductivity, and nutrient value) of 500 ± 2 kg of VW, 250 ± 2 kg of RH, and 19 ± 1 kg of CM feedstock mixture was analyzed. …”
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Preservative-free IOP-lowering medications: potential advantages by I.B. Alekseev, I.A. Koroleva

“…Elimination or minimization of adverse reactions accompanying long-term glaucoma therapy is an important resource to improve treatment compliance and, therefore, to prevent vision loss and to maintain the quality of life. Hence, glaucoma patients may benefit from the avoidance of the addit ional risk of ocular surface disorders resulting from preservative exposure.…”
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Unveiling Low-frequency Eclipses in Spider Millisecond Pulsars Using Wideband GMRT Observations by Sangita Kumari, Bhaswati Bhattacharyya, Devojyoti Kansabanik, Rahul Sharan, Ankita Ghosh, Jayanta Roy

“…We calculated the mass-loss rate of the companion for PSR J1555–2908 and PSR J1810+1744 and found that these rates are insufficient to ablate the companion stars. …”
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Clinical and imaging features of co-existent pulmonary tuberculosis and lung cancer: a population-based matching study in China by Fan Zhang, Fei Qi, Yi Han, Hongjie Yang, Yishuo Wang, Guirong Wang, Yujie Dong, Hongxia Li, Yuan Gao, Hongmei Zhang, Tongmei Zhang, Liang Li

“…Results Compared to LC or IAPTB-LC, patients with APTB-LC exhibited higher proportions of weight loss (p < 0.001) and fever (p < 0.001) at the time of diagnosis. …”
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Additively manufactured biodegradable Zn metamaterials with tunable Poisson’s ratio and enhanced mechanical properties by Yixuan Shi, Jiaqi Gao, Xuan Li, Zui Tao, Chengcong Huang, Shangyan Zhao, Yuzhi Wu, Youwen Yang, Yabin Yang, Yageng Li, Lu-Ning Wang

“…Permeability and in vitro immersion studies revealed that higher permeability accelerated degradation, with the B3 scaffold showing a 19.76% weight loss over 28 days and a yield strength increase of 2.3 MPa. …”
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Improving Visual Field Awareness among Collegiate Softball Athletes: A Randomized Trial by Diana R. Feldhacker, Whitney Lucas Molitor

“…Research indicates improvement of visual field awareness can be gained through use of the Dynavision^TM D2, yet these studies primarily involve subjects with established field loss or post injury, rather than as a training method among well athletes. …”
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A preliminary exploration of establishing a mice model of hypoxic training by Minglu Li, Zhijie Chen, Ziyang He, Xinjuan Zhang, Yanqiu Liu, Hui Zhou, Hang Yang, Tao Liu, Xiaochuan Wang, Ran Zhang, Jiaxing Zhang

“…Meanwhile, hypoxic mice showed significant cognitive impairment, anxiety, depression, muscle loss, and fat gain compared with hypoxic training mice after hypoxia intervation. …”
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Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS by Adam Eckardt, Charles Marble, Bradley Fern, Henry Moritz, Charles Kotula, Jiayi Ke, Clarisse Rebancos, Samantha Robertson, Hiroshi Nishimune, Masatoshi Suzuki, Masatoshi Suzuki

“…Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease characterized by specific loss of motor neurons in the spinal cord and brain stem. …”
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Retinal Protection of New Nutraceutical Formulation by Luca Rosario La Rosa, Veronica Pepe, Francesca Lazzara, Giovanni Luca Romano, Federica Conti, Erika Giuffrida, Claudio Bucolo, Santa Viola, Giuseppe De Pasquale, Maria Cristina Curatolo, Cristina Zappulla

“…Finally, Epicolin treatment on DBA/2J mice protected the RGCs from loss of function, as demonstrated by PERG analysis, and attenuated their death by enhancing brain-derived neurotrophic factor (<i>BDNF</i>) and reducing interleukin-1 beta (<i>IL-1β</i>) and tumor necrosis factor-alpha (<i>TNF-α</i>) expression. …”
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Time-series forest age estimation in Xinjiang based on forest disturbance and recovery detection by Lili Zhai, Mei Zan, Mao Ye, Jia Zhou, Cong Xue, Shunfa Yang, Yuntong Liu

“…The findings revealed that: (1) the R2 values of the RF regression models for estimating forest age exceeded 0.65, with RMSEs below 22 years and RRMSEs ranging from 0.119 to 0.183, demonstrating high credibility of the simulation results; (2) the overall accuracy of the LandTrendr algorithm in identifying forest loss and gain in the study area was 85 % or higher. …”
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Internal Facilitation by Health Assistants for the &ldquo;WHO Lay Health Worker Dementia Care&rdquo; in Rural Uganda: A Formative Evaluation by Wakida EK, Obua C, Rukundo GZ, Samantha M, Maling S, Karungi CK, Talib ZM, Haberer J, Bartels SJ

“…Edith K Wakida,1,2 Celestino Obua,2 Godfrey Zari Rukundo,3 Mary Samantha,2 Samuel Maling,4 Christine K Karungi,2 Zohray M Talib,1 Jessica Haberer,5,6 Stephen J Bartels5,6 1Department of Medical Education, California University of Science and Medicine, Colton, California, USA; 2Department of Research and Development, Alpha Center for Research Administration, Mbarara, Uganda; 3Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada; 4Department of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda; 5Department of Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA; 6Harvard Medical School, Harvard University, Boston, Massachusetts, USACorrespondence: Edith K Wakida, Email Edith.Wakida@cusm.eduBackground: Dementia is characterized by cognitive symptoms like memory loss, difficulty with language, and impaired judgment, alongside behavioral and psychological symptoms such as depression, anxiety, and aggression. …”
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Prevalence and incidence of sarcopenia in Swiss postmenopausal women: findings from the OsteoLaus Cohort by Colin Vendrami, Elena Gonzalez Rodriguez, Guillaume Gatineau, Peter Vollenweider, Pedro Marques-Vidal, Olivier Lamy, Didier Hans, Enisa Shevroja

“… STUDY AIMS: Sarcopenia is a progressive, age-related loss of muscle mass, strength and function. Given the ageing population and the adverse outcomes associated with sarcopenia, monitoring its epidemiology is particularly important. …”
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