Genome evolution following an ecological shift in nectar-dwelling Acinetobacter by Vivianna A. Sanchez, Tanya Renner, Lydia J. Baker, Tory A. Hendry

“…We find that although gene loss coincided with the switch to living in nectar, gains of specific genes from other bacteria may have been particularly important for this ecological change. …”
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Pleiotrophin deletion prevents high-fat diet-induced cognitive impairment, glial responses, and alterations of the perineuronal nets in the hippocampus by Héctor Cañeque-Rufo, Teresa Fontán-Baselga, Milagros Galán-Llario, Agata Zuccaro, María Gracia Sánchez-Alonso, Esther Gramage, María del Pilar Ramos-Álvarez, Gonzalo Herradón

“…Our findings demonstrate that feeding wild-type (Ptn+/+) mice with HFD for 6 months results in short- and long-term memory loss in the novel object recognition task. Surprisingly, we did not observe any sign of cognitive impairment in Ptn−/− mice fed with HFD. …”
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IOP-lowering therapy and ocular surface in glaucoma. Part 2. The effect of preservatives on ocular surface by A.V. Antonova, V.P. Nikolaenko, V.V. Brzheskiy

“…Dose-dependent and time-dependent loss of goblet cells, expansion and activation of fibroblast populations, release of proinflammatory cytokines by conjunctival cells account for dry eye symptoms and signs, poor adherence to treatment, and poor results of glaucoma filtration surgery.…”
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A cost–benefit analysis of the production system with improved and climate-resilient sorghum varieties in southern Mali by Adama B. Coulibaly, Félix Badolo, Félix Badolo, Jummai O. Yila, Jummai O. Yila, Bourema Koné, Baloua Nebié, Baloua Nebié, Nadine Worou, Nadine Worou, Macdonald Bright Jumbo, Kimseyinga Savadogo

“…The key findings showed that both varieties were profitable, with 79,661 CFA (123.56 USD) and 45,073 CFA (69.91 USD) average net incomes corresponding to 1.54 and 1.32 CBR, and 34 and 24 percents average gross profit margins, respectively, while growing the “local” varieties was not profitable, with an average loss of 12,113 CFA (18.79 USD) with 0.91 CBR and 10 percent average gross profit margin. …”
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Side effects of psychotropic drugs on eye by A.A. Petukhova, A.A. Panov, Ya.V. Malygin, M.A. Kazanfarova

“…., topiramate) is associated with high risks of vision loss. Moreover, in some patients these medications may result in blindness. …”
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Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy by Hemanathan Vembuli, Sheeja Rajasingh, Patrick Nabholz, Jefferson Guenther, Brian R. Morrow, Margaret M. Taylor, Marziyeh Aghazadeh, Vinoth Sigamani, Johnson Rajasingh, Johnson Rajasingh, Johnson Rajasingh

“…Bone fractures and bone loss represent significant global health challenges, with their incidence rising due to an aging population. …”
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Experiences and overall impact reported by people living with obesity: results from a multinational study by Esther Artime, Swarna Khare, Sarah Zimner-Rapuch, Josefine Redig, Caragh Flannery, Victoria Higgins, Andrea Leith, Ashley Mortimer, Bruno Halpern, Nasreen Alfaris

“…People/patients with obesity struggled with weight for a mean ± SD of 64.1 ± 86.6 months with a median (interquartile range) of 3.0 (2.0–5.0) weight-loss attempts. Mean ± standard deviation 36-Item Short Form Health Survey scores for people/patients with obesity above the obesity threshold showed impairment in general health (42.3 ± 11.5), social functioning (44.3 ± 9.2), role-emotional (46.0 ± 9.3), and mental health (45.7 ± 9.6). …”
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Lifestyle Interventions Targeting Body Weight Changes during the Menopause Transition: A Systematic Review by Janet Jull, Dawn Stacey, Sarah Beach, Alex Dumas, Irene Strychar, Lee-Anne Ufholz, Stephanie Prince, Joseph Abdulnour, Denis Prud’homme

“…The other two studies with higher risk of bias suggested that exercise might attenuate weight loss or weight gain and change abdominal adiposity patterns. …”
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Management of acute bacterial meningitis in a limited resource setting: an Egyptian consensus model by Samy Zaky, Mohamed Elbadry, Maysaa A. Saeed, Hanaa Fathelbab, Fatma Abdelsalam, Mohammed Gamal Abdel-Hamid, Alshaimaa Eid, Asmaa Bakr, Amira Maher, Mona Mohammed Abdelrahman, Mohamed A. Metwally, Mahmoud Saad Berengy, Enaam Ali AlMowafy, Hassan Goabar, Amin Abdel Baki, Ahmed Corie, Osama Hammad, Entesar Elsharkawy, Ahmed Saad, Fatma Ali-Eldin, Ahmed Mahdy, Ramadan Zaky, Reham Hammad, Gamal Essmat

“…Those who do recover, especially if there was delayed appropriate intervention, can have permanent disabilities, such as brain damage, hearing loss, and learning disabilities. Rapid intervention in such cases is mandatory, which is not easy in countries with limited income due to weak capabilities and resources. …”
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The role of Latin America medicinal plants in wound healing by Mariana Sánchez-Ramos, Andrea Ruiz-Betancourt, Stephany Abigail Tadeo-Cuenca, Angélica Román-Guerrero, María Crystal Columba-Palomares, Araceli Guerrero-Alonso, Antonio Bernabé-Antonio, Deyanira Ojeda-Ramírez, Francisco Cruz-Sosa

“…Wound healing represents a global public health problem when it is not treated correctly, which can cause complications for the patient, such as functional loss of an organ, amputation, and even death. At a biological level, wound healing involves a complex mechanism in which the immune system and cellular biochemical cascades intervene in a coordinated manner, whose development occurs in stages such as inflammation, proliferation, and remodeling. …”
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Creatine monohydrate administration delayed muscle glycolysis of antemortem-stressed broilers by enhancing muscle energy status, increasing antioxidant capacity and regulating musc... by Ning Liu, Qingzhen Zhong, Zewei Sun, Bolin Zhang

“…The results showed that preslaughter stress led to a lower pH24 h value, a bigger L* value and a higher drip loss of muscle compared with the control group (P < 0.05). …”
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The chromatin remodeling factor OsINO80 promotes H3K27me3 and H3K9me2 deposition and maintains TE silencing in rice by Kangxi Du, Jiabing Wu, Jiachen Wang, Wenhao Xie, Liufan Yin, Xiang Li, Chao Li, Aiwu Dong

“…Upon OsINO80 overexpression in rice, we found three types of OsINO80-occupied regions with different chromatin signatures: type I (enriched with H2A.Z), type II (enriched with H3K9me2), and type III (deficient in H2A.Z/H3K9me2). Loss of OsINO80 results in a decrease in H3K27me3, but not H2A.Z, at type I regions as well as a decrease in H3K9me2 at type II regions, which correlates with TE activation and transposition. …”
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Dynamics of spatial phase coherence in a dissipative Bose–Hubbard atomic system by Vatré, Rémy, Bouganne, Raphaël, Bosch Aguilera, Manel, Ghermaoui, Alexis, Beugnon, Jérôme, Lopes, Raphael, Gerbier, Fabrice

“…We investigate the loss of spatial coherence of one-dimensional bosonic gases in optical lattices illuminated by a near-resonant excitation laser. …”
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The Impact of Optical Undersampling on the Ca2+ Signal Resolution in Ca2+ Imaging of Spontaneous Neuronal Activity by Katarina D. Milicevic, Violetta O. Ivanova, Tina N. Brazil, Cesar A. Varillas, Yan M.D. Zhu, Pavle R. Andjus, Srdjan D. Antic

“…Conclusions: Our findings reveal that Ca2+ signal undersampling leads to three types of information loss: (1) distortion of rise times and durations for large-amplitude transients, (2) failure to detect small-amplitude transients in cell bodies, and (3) omission of small-amplitude transients in the neuropil.…”
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Real-Time Analytics and AI for Managing No-Show Appointments in Primary Health Care in the United Arab Emirates: Before-and-After Study by Yousif Mohamed AlSerkal, Naseem Mohamed Ibrahim, Aisha Suhail Alsereidi, Mubaraka Ibrahim, Sudheer Kurakula, Sadaf Ahsan Naqvi, Yasir Khan, Neema Preman Oottumadathil

“…No-show appointments are significant contributors to inefficiency in PHC operations, which can lead to an estimated 3%-14% revenue loss, disrupt resource allocation, and negatively impact health care quality. …”
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Differences in pyrolysis behavior and volatiles of tar-rich coal with various origins by Qingmin Shi, Xinyue Zhao, Shuangming Wang, Hongchao Zhao, Ruijun Ji, Chunhao Li, Bingyang Kou, Jun Zhao

“…Compared to others, S-1, formed in a stronger reducing environment, had a 17 °C lower initial pyrolysis temperature, a 5 °C lower peak reaction temperature, and a 20 % higher weight loss. The reason for S-1 had more bonds with lower energies, accounting for 76 % of the total fragmented bonds, which was 10 % higher than others. …”
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Village Savings and Loan Associations and Socio-Economic Empowerment of Vulnerable People in Kamuganguzi Sub-County Kabale, District, Uganda by Mwijukye, Deus, Moses, Agaba

“…The recommendations were; need to improving the health status of women in families as well as children since they are regarded vulnerable in order to let them live happily; there should be improved nutrition and food supply to all families to let children and other members grow healthy and live a happy life; increased household income should be the ultimate goal fostered by credit accessibility in the area which must be done with ease through the start of small and medium enterprises especially women; it is recommended that the vulnerable groups of people have the replacement of the damaged property in case of any loss aiming at keeping standards of living at household level; achieving flexibility to immense development of social capital required the development of the saving culture that promotes regular income to help the community solve their personal problems; the social fund should be a unifying factor that enhances development through increased social networking to allow information flow since information is power…”
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Village Savings And Loan Associations (VSLA) and Socio -Economic Empowerment of Vulnerable People in Kamuganguzi Sub County Kabale District. by Mwijukye, Deus

“…The recommendations were; need to improving the health status of women in families as well as children since they are regarded vulnerable in order to let them live happily; there should be improved nutrition and food supply to all families to let children and other members grow healthy and live a happy life; increased household income should be the ultimate goal fostered by credit accessibility in the area which must be done with ease through the start of small and medium enterprises especially women; it is recommended that the vulnerable groups of people have the replacement of the damaged property in case of any loss aiming at keeping standards of living at household level; achieving flexibility to immense development of social capital required the development of the saving culture that promotes regular income to help the community solve their personal problems; the social fund should be a unifying factor that enhances development through increased social networking to allow information flow since information is power. …”
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Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells by Chu-An Wang, Ya-Chin Hou, Yi-Kai Hong, Yu-Jing Tai, Chieh Shen, Pei-Chi Hou, Jhao-Lin Fu, Cheng-Lin Wu, Siao Muk Cheng, Daw-Yang Hwang, Yung-Yeh Su, Yan-Shen Shan, Shaw-Jenq Tsai

“…The ERKactiveDUSP2low cancer cells further exacerbate macrophage-mediated cancer malignancy, including loss of epithelial trait, increased lymphangiogenesis, and immune escape. …”
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SNORA37/CMTR1/ELAVL1 feedback loop drives gastric cancer progression via facilitating CD44 alternative splicing by Banghe Bao, Minxiu Tian, Xiaojing Wang, Chunhui Yang, Jiaying Qu, Shunchen Zhou, Yang Cheng, Qiangsong Tong, Liduan Zheng

“…Results SNORA37 was identified as an up-regulated snoRNA essential for tumorigenesis and aggressiveness of gastric cancer. Gain- and loss-of-function studies indicated that SNORA37 promoted the growth, invasion, and metastasis of gastric cancer cells in vitro and in vivo. …”
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