Understanding regular exercise behavior in frail older adults: a structural equation model based on social-cognitive variables by Shiqi Yu, Jie Lin, Siping Song, Shuqi Huang, Fan Liu, Mingzhao Xiao

“…There were statistically significant differences in the regular exercise behavior for demographic characters of occupation, disposable monthly income, frail phenotype of fatigue, resistance and weight loss (p < 0.05). SEM showed that the exercise self-efficacy (β = 0.52, p < 0.001) and exercise outcome expectation (β = 0.45, p < 0.011) are the strongest determinants of regular exercise behavior, while social support (β = 0.092, p > 0.05) and self-regulation (β = 0.05, p > 0.05) are non-determinant. …”
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Taguchi Parametric Optimization of Theobroma Cocoa-Derived Magnetite Nanoparticles: Synthesis, Pegylation, and Magnetic Hyperthermia Potential by Mohamed Abdelsamea, O. M. Lemine, Emma Ziezie Ziezie, Mohd Tarmizi, Norazalina Saad, Huey Fang Teh, Ahmad Kamil Mohd Jaaffar, Mohamed Ahmed Ibrahim, Che Azurahanim Che Abdullah

“…Remarkably, at a concentration of 5 mg/mL, MNPs, and Pegylated-MNPs quickly dissipated heat, achieving maximum intrinsic loss powers (ILP) of 1.29 nHm²/kg and 0.694 nHm²/kg and specific absorption rates (SAR) of 135.17 W/g and 60.18 W/g. …”
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Identifying the Factors That Drive Health Service Utilization Among Healthy and Non‐Healthy Agers in a Sample of Older Ethiopians: A Cross‐Sectional Study by Amare Belachew, Nicolas Cherbuin, Nasser Bagheri, Richard Burns

“…This presents a significant challenge to healthcare systems, particularly in developing countries, as untreated chronic conditions can lead to years of disability and loss of independence straining health budgets and resources. …”
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HDAC6 inhibitor-loaded brain-targeted nanocarrier-mediated neuroprotection in methamphetamine-driven Parkinson's disease by Khang-Yen Pham, Shristi Khanal, Ganesh Bohara, Nikesh Rimal, Sang-Hoon Song, Thoa Thi Kim Nguyen, In-Sun Hong, Jinkyung Cho, Jong-Sun Kang, Sooyeun Lee, Dong-Young Choi, Simmyung Yook

“…Parkinson's disease (PD), a neurodegenerative disorder marked by α-synuclein (α-syn) accumulation and dopaminergic neuron loss in the substantia nigra, is associated with a disruption of this balance. …”
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Renal Dysfunction after Living-Donor Liver Transplantation: Experience with 500 Cases by Ehab E. Abdel-Khalek, Alrefaey K. Alrefaey, Amr M. Yassen, Ahmed Monier, Hesham M. Elgouhari, Mohamed Samy Habl, Gehad Tawfik, Thuraya Elzayat, Reham Adly Zayed, Mohamed Abdel-Wahab

“…Univariate regression analysis for predicting the likelihood of chronic kidney disease at 1 year revealed that the following 4 variables were significant: operative time, P < 0.0005; intraoperative blood loss, P < 0.0005; preoperative renal impairment, P = 0.001; and graft-to-recipient weight ratio (as a negative predictor), P < 0.0005. …”
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Features of test of air-fuel system of gas turbine engine by V. N. Klimov, D. Ya. Dud’ev, V. Ya. Sigaylo, N. I. Klimov

“…This makes it much more difficult to select the optimal parameters of the air-fuel mixture and the operating modes of the engine, ensuring the operability of its rotary bearings with the least loss of fuel and air pressure behind the compressor, which can lead to a significant deterioration of the main parameters of the GTE. …”
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Diagnostics and treatment of cardiac achalasia and cardiospasm: guidelines of the Russian gastroenterological association by V. T. Ivashkin, A. S. Trukhmanov, E. A. Godzhello, I. V. Mayev, Yu. V. Evsyutina, T. L. Lapina, O. A. Storonova

“…Clinical symptoms of disease: difficulty of passage of solid and liquid food through the esophagus, vomiting, in certain cases - chest pain; severe disease is accompanied by cough and weight loss. Differential diagnosis is carried out with cardioesophageal cancer, peptic stricture, esophageal webs and rings, neurogenic anorexia and coronary heart disease in the cases with chest pain. …”
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Olivetol’s Effects on Metabolic State and Gut Microbiota Functionality in Mouse Models of Alimentary Obesity, Diabetes Mellitus Type 1 and 2, and Hypercholesterolemia by Anastasia A. Zabolotneva, Katerina E. Popruga, Valentin V. Makarov, Sergei M. Yudin, Andrei M. Gaponov, Sergei A. Roumiantsev, Aleksandr V. Shestopalov

“…Results: According to the results of the study, olivetol caused a lowering of body weight in C57Bl6 mice fed a high-fat diet and in <i>ldlr</i>(−/−) mice, decreased serum glucose levels in <i>db</i>/<i>db</i> mice, improved lipid metabolism in <i>ldlr</i>(−/−) mice, and prevented inflammatory infiltration of the pancreas and loss of insulin secretion in NOD mice. In addition, olivetol affected the composition and functional activity of gut microbiota communities, inducing an expansion of probiotic species such as <i>Akkermansia muciniphila</i> and <i>Bacteroides acidifaciens</i> and depleting the representation of pathobionts such as <i>Prevotella</i>, although olivetol supplementation did not influence the diversity or richness of the communities. …”
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Avolition Characterizes the Chronic Fatigue Experienced in Quiescent Inflammatory Bowel Disease by Tristan Gabriel-Segard, Margherita Boltri, Mathilde Barrau, Catherine Massoubre, Stéphane Paul, Xavier Roblin

“…It refers to a motivation loss for initiating and maintaining goal-directed activities, often called fatigue by patients. …”
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CHAMP1 premature termination codon mutations found in individuals with intellectual disability cause a homologous recombination defect through haploinsufficiency by Yujiro Yoshizaki, Yunosuke Ouchi, Dicky Kurniawan, Eisuke Yumoto, Yuki Yoneyama, Faiza Ramadhani Rizqullah, Hiyori Sato, Mirjam Hanako Sarholz, Toyoaki Natsume, Masato T. Kanemaki, Masanori Ikeda, Ayako Ui, Kenji Iemura, Kozo Tanaka

“…U2OS cells expressing the CHAMP1 mutants did not show an HR defect in the presence of endogenous wild-type (WT) CHAMP1, whereas they were unable to restore HR activity when CHAMP1 WT was depleted, suggesting that the PTC mutations are loss-of-function mutations. On the other hand, the CHAMP1 mutants with missense mutations restored HR activity when CHAMP1 WT was depleted. …”
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Extreme migratory connectivity and apparent mirroring of non-breeding grounds conditions in a severely declining breeding population of an Afro-Palearctic migratory bird by Máire Kirkland, Nathaniel N. D. Annorbah, Lee Barber, John Black, Jeremy Blackburn, Michael Colley, Gary Clewley, Colin Cross, Mike Drew, Oliver J. L. Fox, Vicky Gilson, Steffen Hahn, Chas Holt, Mark F. Hulme, John Jarjou, Dembo Jatta, Emmanuel Jatta, Kevin Leighton, Ernestina Mensah-Pebi, Chris Orsman, Naffie Sarr, Roger Walsh, Leo Zwarts, Robert J. Fuller, Philip W. Atkinson, Chris M. Hewson

“…High connectivity (low non-breeding population dispersion) may lower resilience to climate change and increase vulnerability to habitat loss within their range. Very high levels of connectivity are reportedly rare, but this conclusion may be limited by methodology. …”
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Sterol‐Targeted Laboratory Evolution Allows the Isolation of Thermotolerant and Respiratory‐Competent Clones of the Industrial Yeast Saccharomyces cerevisiae by Isabel‐Elena Sánchez‐Adriá, Jose A. Prieto, Gemma Sanmartín, Miguel Morard, Estéfani García‐Ríos, Francisco Estruch, Francisca Randez‐Gil

“…The clones were categorised into two groups based on their respiratory competence or deficiency, the latter associated with mtDNA loss, an event seemingly linked to FCNZ and heat tolerance. …”
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Randomised controlled trial comparing intraoperative cell salvage and autotransfusion with standard care in the treatment of hip fractures: a protocol for the WHITE 9 study by Mike Murphy, Nicholas Parsons, James Mason, Juul Achten, Duncan Appelbe, Edward Dickenson, Damian Griffin, Katy Mironov, Matthew Wyse, Amrita Athwal, Xavier Luke Griffin, Heather O'Connor

“…Hip fracture and the urgent surgery is associated with acute blood loss, compounding patients’ pre-existing comorbidities including anaemia. …”
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The impact of the COVID-19 pandemic on the research activity and working experience of clinical academics, with a focus on gender and ethnicity: a qualitative study in the UK by Carmen Soto, Jessica Elizabeth Morgan, Paul Crampton, Paul Alexander Tiffin, Gabrielle M Finn, Amelia Kehoe, Ellie Taylor, John AG Buchanan, Abisola Olatokunbo Balogun

“…Interventions are needed to mitigate the potential lasting impact on capacity from the pandemic, and the potential for the loss of women from this valuable workforce.…”
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Large-Scale Neuronal Network Dysfunction in Diabetic Retinopathy by Xin Huang, Yan Tong, Chen-Xing Qi, Han-Dong Dan, Qin-Qin Deng, Yin Shen

“…Our results offer important insights into the neural mechanisms of visual loss and cognitive decline in DR patients.…”
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Ecological reef restoration: consumptive and nonconsumptive interactions among common North Sea predators and European oysters by Julius A. Ellrich, Clemens Kozian-Fleck, Markus Brand, Bérenger Colsoul, Bérenger Colsoul, Bernadette Pogoda, Bernadette Pogoda

“…To halt and reverse the associated biodiversity loss, oyster reef restoration was implemented into marine conservation measures and several reef restoration projects started across Europe. …”
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Barriers and facilitators of integrated hepatitis B, C, and HIV screening among pregnant mothers and newborns attending maternal and newborn clinics in Koboko District, Uganda: a q... by John Bosco Alege, John Paul Oyore, Rose Clarke Nanyonga, Philippa Musoke, Alloys S. S. Orago

“…Patients with HBV do not receive routine counselling and education, and there are limited resources for laboratory investigation coupled with a high loss to follow-up. This study set out to assess barriers and facilitators of integrated viral hepatitis B C and HIV care model to optimize screening uptake among mothers and newborns at health facilities in Koboko District, west Nile sub-region, Uganda. …”
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Vitamin D Deficiency as a Risk Factor for Diabetic Retinopathy: A Systematic Review and Meta-Analysis by Claudia Elena Petrea, Laura Andreea Ghenciu, Roxana Iacob, Emil Robert Stoicescu, Dorel Săndesc

“…Diabetic retinopathy (DR), a significant microvascular complication of diabetes mellitus (DM), remains a major cause of vision loss worldwide. Vitamin D, recognized for its role in bone health, has also been implicated in various non-skeletal conditions, including DR. …”
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Enhanced pedestal transport driven by edge collisionality on Alcator C-Mod and its role in regulating H-mode pedestal gradients by M.A. Miller, J.W. Hughes, A.M. Rosenthal, S. Mordijck, R. Reksoatmodjo, M. Wigram, J. Dunsmore, F. Sciortino, R.S. Wilcox, T. Odstrčil

“…Enhanced D _α experiments on Alcator C-Mod observed pedestal degradation and loss in confinement below a critical value of net power crossing the separatrix, $P_\mathrm{net} = P_\mathrm{net}^\mathrm{crit} \approx 2.3$ MW, in the absence of any external fueling. …”
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Olfactory impairment in Italian patients with chronic rhinosinusitis with nasal polyps: a patient-centered survey by Francesca Anastasi, Francesca Anastasi, Frank Rikki Mauritz Canevari, Frank Rikki Mauritz Canevari, Stefania Gallo, Giulia Gramellini, Enrico Heffler, Enrico Heffler, Ignazio La Mantia, Giulia Monti, Martina Ragusa, Alberto Macchi

“…CRSwNP significantly impairs quality of life (QoL), with olfactory loss being a particularly distressing symptom that affects food enjoyment, personal safety, and social interactions.MethodsThis study investigated the experiences of Italian patients with CRSwNP. …”
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