Attitudes of radiologists and interns toward the adoption of GPT-like technologies: a National Survey Study in China by Tianyi Xia, Shijun Zhang, Ben Zhao, Ying Lei, Zebin Xiao, Bingwei Chen, Junhao Zha, Yaoyao Yu, Zhijun Wu, Chunqiang Lu, Tianyu Tang, Yang Song, Yuancheng Wang, Shenghong Ju

“…Most Chinese radiologists express the supportive adoption of GPT-like technologies. …”
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A Model for Bank Management Performance Appraisal with the Advanced Technologies Approach (Meta-Synthesis Method) by Ehsan Kiani Ghalehno, Habibollah Salarzehi, Bahareh Naseri, Abdolali Keshtegar

“…Such measures lead to bank changes, discussion of the bank's problems, solving problems, and preparing the bank for a successful future.IntroductionAccording to reconstruction experts, if people are free to express their opinions and feelings, have peace of mind, and discuss conflicts freely, changes will be effectively made, leading to improvement in banking performance (Kamalian , 2013). …”
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Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

“…While epilepsy and psychiatric behaviors increase in severity with age, communication abilities and motor function tend to improve. iPSCs, which were differentiated into GABAergic neurons, represent the first in vitro neuronal model of SSADHD and express the neuronal marker microtubule-associated protein 2 (MAP2), as well as GABA. …”
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Epistemic Roots, Universal Routes and Ontological Roofs of African “Ritual Archives”: Disciplinary Formations in African Thought by Oluwatoyin Vincent Adepoju

“…This response is organized in five parts, representing my understanding of the five major thematic strategies through which the central idea is laid out and expanded. 316 Oluwatoyin Vincent Adepoju The first section, “Developing Classical African Expressions as Sources of Locally and Universally Valid Theory” explores Falola’s advocacy for an expanded cultivation of theory from Africa created and Africa inspired expressive forms. …”
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Monoclonal antibody development and antigenic epitope identification of chicken pro-IL-1β by Mengmeng Xu, Mengmeng Huang, Guodong WANG, Jingzhe HAN, Xinxin NIU, Jinze HAN, Hangbo YU, Yulong ZHANG, Runhang LIU, Ziwen WU, Hongyu Cui, Yanping Zhang, Suyan Wang, Yongzhen Liu, Yuntong Chen, Yulu Duan, Liuan Li, Yulong Gao, Xiaole Qi

“…This study cloned and expressed chicken pro-IL-1β, and developed a hybridoma cell line 1E12 capable of stably secreting chicken pro-IL-1β monoclonal antibody (mAb). …”
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Effect of Interleukin-17 in the Activation of Monocyte Subsets in Patients with ST-Segment Elevation Myocardial Infarction by Montserrat Guadalupe Garza-Reyes, Mónica Daniela Mora-Ruíz, Luis Chávez-Sánchez, Alejandra Madrid-Miller, Alberto Jose Cabrera-Quintero, José Luis Maravillas-Montero, Alejandro Zentella-Dehesa, Luis Moreno-Ruíz, Selene Pastor-Salgado, Erick Ramírez-Arias, Nataly Pérez-Velázquez, Adriana Karina Chávez-Rueda, Francisco Blanco-Favela, Wendy Guadalupe Vazquez-Gonzalez, Alicia Contreras-Rodríguez

“…Furthermore, IL-17 increased the expression of TLR4 on CD14+CD16- and CD14++CD16+/CD14+CD16++ monocytes post-STEMI and might enhance the response to danger-associated molecular patterns post-STEMI. …”
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Genetic Mutations of Tim-3 Ligand and Exhausted Tim-3+ CD8+ T Cells and Survival in Diffuse Large B Cell Lymphoma by Tingting Zhang, Tianyuan Ren, Zheng Song, Jing Zhao, Lei Jiao, Zhenzhen Zhang, Jin He, Xianming Liu, Lihua Qiu, Lanfang Li, Shiyong Zhou, Bin Meng, Qiongli Zhai, Xiubao Ren, Zhengzi Qian, Xianhuo Wang, Huilai Zhang

“…Multiplexed immunofluorescence revealed that patients with Tim-3-expressing tumor-infiltrating lymphocytes (Tim-3+ TILs) exhibited poor outcomes than those with Tim-3- TILs (p=0.041). …”
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Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study by Heinz Wiendl, Frederik Barkhof, Frederik Barkhof, Xavier Montalban, Anat Achiron, Anat Achiron, Tobias Derfuss, Andrew Chan, Suzanne Hodgkinson, Alexandre Prat, Letizia Leocani, Letizia Leocani, Letizia Leocani, Klaus Schmierer, Klaus Schmierer, Finn Sellebjerg, Finn Sellebjerg, Patrick Vermersch, Hulin Jin, Anita Chudecka, Andreas Kloetgen, Dongdong Lin, Lidia Gardner, Nicola De Stefano

“…The safety profile was consistent with previous reports.DiscussionDeep longitudinal immunophenotyping, analysis of transcriptional changes, reduction in cells expressing pro-inflammatory cytokines, along with the marker of neuroaxonal damage provide novel and innovative evidence of CladT rebalancing the immune system towards a more homeostatic and less pathogenic state.Clinical Trial Registrationhttps://clinicaltrials.gov/study/, identifier NCT03364036.…”
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Evaluation of S100A8/A9 and neutrophils as prognostic markers in metastatic melanoma patients under immune-checkpoint inhibition by Yasmin F Melzer, Nadine L Fergen, Christian Mess, Julia-Christina Stadler, Glenn Geidel, Ysabel A Schwietzer, Julian Kött, Klaus Pantel, Stefan W Schneider, Jochen Utikal, Ewa Wladykowski, Sabine Vidal-y-Sy, Alexander T Bauer, Christoffer Gebhardt

“…Furthermore, in 113 melanoma patients, neutrophil expression in the tumor microenvironment (TME) was associated with relapse and reduced survival. …”
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Using multiomic integration to improve blood biomarkers of major depressive disorder: a case-control studyResearch in context by Amazigh Mokhtari, El Chérif Ibrahim, Arnaud Gloaguen, Claire-Cécile Barrot, David Cohen, Margot Derouin, Hortense Vachon, Guillaume Charbonnier, Béatrice Loriod, Charles Decraene, Ipek Yalcin, Cynthia Marie-Claire, Bruno Etain, Raoul Belzeaux, Andrée Delahaye-Duriez, Pierre-Eric Lutz

“…Methods: We characterised gene expression and two mechanisms of epigenomic regulation, DNA methylation (DNAm) and microRNAs (miRNAs), in blood samples from a cohort of individuals with MDD and healthy controls (n = 169). …”
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First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors by Ignacio I Wistuba, Mamta Kalra, Linus Backert, Martin Wermke, Edwin R Parra, Jason John Luke, Apostolia M Tsimberidou, Sebastian Bunk, Mohammad B Hossain, Andrea Mayer-Mokler, Arun Satelli, Norbert Hilf, Steffen Walter, Cedrik M Britten, Van K Morris, Tobias A W Holderried, Winfried H Alsdorf, Katrin Wetzko, Borje S Andersson, Sandra Grund-Gröschke, Katrin Aslan, Anantha Marisetty, Swapna Satam, Jens Hukelmann, M Alper Kursunel, Karine Pozo, Andreas Acs, Melissa Baumeister, Claudia Wagner, Oliver Schoor, Ali S Mohamed, Delfi Krishna

“…IMA202 consists of autologous genetically modified cytotoxic CD8+ T cells expressing a T cell receptor (TCR), which is specific for a nine amino acid peptide derived from MAGEA1. …”
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piR-26441 inhibits mitochondrial oxidative phosphorylation and tumorigenesis in ovarian cancer through m6A modification by interacting with YTHDC1 by Jing Yuan, Bu-Min Xie, Yu-Meng Ji, Hai-Juan Bao, Jie-Lin Wang, Jia-Chen Cheng, Xiang-Chun Huang, Yang Zhao, Shuo Chen

“…Furthermore, piR-26441 directly binds to and upregulates the expression of YTHDC1 in OC cells. piR-26441 also increased m6A levels, thereby interacting with YTHDC1 to destabilize the mRNA of TSFM. …”
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The bile acid chenodeoxycholic acid associates with reduced stroke in humans and mice by Vera F. Monteiro-Cardoso, Xin Yi Yeo, Han-Gyu Bae, David Castano Mayan, Mariam Wehbe, Sejin Lee, Kumar Krishna-K, Seung Hyun Baek, Leon F. Palomera, Lik Hang Wu, Leroy S. Pakkiri, Sangeetha Shanmugam, Kai Ping Sem, Mun Geok Yew, Matthew P. Parsons, Michael R. Hayden, Leonard L.L. Yeo, Vijay K. Sharma, Chester Drum, Elisa A. Liehn, Sreedharan Sajikumar, Svend Davanger, Dong-Gyu Jo, Mark Y.Y. Chan, Benjamin Y.Q. Tan, Sangyong Jung, Roshni R. Singaraja

“…Synaptic NMDAR activity was also decreased in Cyp8b1−/− brains. Expression and synaptic distribution of GluN2B were unaltered in Cyp8b1−/− mice, suggesting CDCA may directly antagonize GluN2B-containing NMDARs. …”
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Unraveling the immunological landscape and gut microbiome in sepsis: a comprehensive approach to diagnosis and prognosisResearch in context by Yali Luo, Jian Gao, Xinliang Su, Helian Li, Yingcen Li, Wenhao Qi, Xuling Han, Jingxuan Han, Yiran Zhao, Alin Zhang, Yan Zheng, Feng Qian, Hongyu He

“…Immunophenotype shifts were evaluated using differential expression sliding window analysis, and random forest models were developed for sepsis diagnosis or prognosis prediction. …”
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Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice by Marit Hjorth, Casey L. Egan, Guilherme D. Telles, Martin Pal, David Gallego-Ortega, Oliver K. Fuller, Emma D. McLennan, Ryan D. Gillis, Tae Gyu Oh, George E.O. Muscat, Surafel Tegegne, Michael S.M. Mah, Joanna Skhinas, Emma Estevez, Timothy E. Adams, Matthew J. McKay, Mark Molloy, Kevin I. Watt, Hongwei Qian, Paul Gregorevic, Thomas R. Cox, Pernille Hojman, Julie Midtgaard, Jesper F. Christensen, Martin Friedrichsen, Renato V. Iozzo, Erica K. Sloan, Brian G. Drew, Jørgen F.P. Wojtaszewski, Martin Whitham, Mark A. Febbraio

“…We identify the proteoglycan decorin as a contraction-induced secretory factor that systemically increases in patients with breast cancer immediately following exercise. Moreover, high expression of decorin in tumors is associated with improved prognosis in patients, while treatment of breast cancer cells in vitro with decorin reduces cell proliferation. …”
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Estimating Suitable Areas for Dry Almond (Amygdalus communis L.) Cultivation Development in Fars Province using Geographic Information System (GIS) by Ayatollah Karami, Alireza Salehi, Vida Aliyari

“…The results of this study can be valuable to all individuals and organizations active in the field of agricultural development and land resource management (including farmers and horticulturists in Fars province, officials and policymakers related to agriculture and rural development, researchers, and academics in geology, agriculture, and sustainable natural resource development in Fars province) and assist them in decision making regarding almond cultivation development.AcknowledgementsThe authors of the present study would like to express their gratitude to the collaboration of the National Meteorological Organization for providing the necessary data for this research.…”
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Passive exposure and perceptions of smoke-free policies in hospital and university campuses among nursing students: A cross-sectional multicenter study by Marcela Fu, Yolanda Castellano, Kenza Laroussy, Antoni Baena, Mercè Margalef, Ariadna Feliu, Jordi Galimany-Masclans, Montse Puig-Llobet, Carmen Moreno-Arroyo, Raül Sancho, Albert Bueno, Antonio López, Joseph Guydish, Esteve Fernández, Cristina Martínez

“…Conclusions Exposure to SHS on university campuses is high. Nursing students express low support for strengthening outdoor smoking bans on hospital and university campuses. …”
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Comparison of objectively measured and estimated cardiorespiratory fitness to predict all-cause and cardiovascular disease mortality in adults: A systematic review and meta-analysi... by Ben Singh, Cristina Cadenas-Sanchez, Bruno G.G. da Costa, José Castro-Piñero, Jean-Philippe Chaput, Magdalena Cuenca-García, Carol Maher, Nuria Marín-Jiménez, Ryan McGrath, Pablo Molina-García, Jonathan Myers, Bethany Gower, Francisco B. Ortega, Justin J. Lang, Grant R. Tomkinson

“…We included full-text refereed cohort studies published in English that quantified the association (using risk estimates with 95% confidence intervals (95%CIs)) of objectively measured, exercise-estimated, and non-exercise-estimated CRF with all-cause and CVD mortality in adults. CRF was expressed as metabolic equivalents (METs) of task. …”
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De l’agglomération antique de Cassinomagus au village de Chassenon (Charente) : un bilan des connaissances by Lucie Carpentier, Sandra Sicard

“…In this context, the Chenevières sanctuary, spanning an area of 7 ha, was to play an essential role in community life as a gathering place, but also as a place of expression of the power of men and gods. The city reveals the first signs of abandonment at the beginning of the 2nd c. …”
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Nécropoles multipolaires et élaboration d’un nouveau modèle socio-politique au premier âge du Fer : réflexions à partir des sites du Camp de l’Église Sud à Flaujac-Poujols (Lot) et... by Antoine Dumas

“…Given that, in the protohistoric world as in others, necropolises are to be considered places of ideological expression, this implies that, between the global crisis which marks the end of the Bronze Age during the 9th c. …”
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