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16141
Implementation strategies: lessons learned during an e-learning intervention to improve dietary behaviors and feeding practices in early childhood education and care
Published 2025-01-01“…I prefer when peers share experiences. 3) Newsletters were helpful and reminded me, but I do not always have enough time to read. 4) Evaluations have increased my awareness, and we do them informally and formally. 5) The regular phone calls reminded me I could receive support and express my opinion. Conclusion This study’s findings suggest that several implementation strategies are acceptable for stakeholders in an ECEC e-learning healthy eating intervention. …”
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16142
Therapeutic potential of the neutralizing monoclonal antibody 45G3 against encephalomyocarditis virus
Published 2025-01-01“…Using recombinant DNA technology, we engineered a baculovirus system to express EMCVs P12A and 3C, facilitating the production of VLPs in Sf9 cells. …”
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16143
Similarities and Differences between ICME-driven Shocks Observed by VEX (∼0.72 au) and WIND (∼1.0 au)
Published 2025-01-01“…The features of interplanetary shocks driven by interplanetary coronal mass ejections (ICMEs) observed by WIND (∼1.0 au) and Venus Express (VEX; ∼0.72 au) during the same period are statistically analyzed by comparing their similarities and differences. …”
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16144
Alterations in physicochemical parameters of water and the growth performance of juvenile beluga Huso huso in earthen ponds
Published 2024-06-01“…Ensuring optimal environmental conditions, particularly in earthen ponds, can increase productivity in the sturgeon fish farming industry.Funding: This research did not receive a specific grant from any funding agency in the public, commercial, or not-for-profit sectors.Conflicts of interest: The authors have no conflicts of interest to declare.Acknowledgments: The authors would like to express gratitude for the valuable assistance provided by the officials and employees of the Shahid Marjani Sturgeon Propagation Centre.…”
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16145
Hubungan Kecanduan Bermain Video Games Kekerasan dengan Perilaku Agresif pada Murid Laki-laki Kelas IV dan V di SD Negeri 02 Cupak Tangah Pauh Kota Padang
Published 2015-01-01“…Data dikumpulkan melalui wawancara kepada responden menggunakan kuesioner yang kemudian di analisis dengan uji statistik chi-square dengan derajat kepercayaan 95% (0,05).Hasil penelitian menunjukkan persentase responden yang memiliki perilaku agresif lebih tinggi pada responden yang mengalami kecanduan bermain video games yang mengandung unsur kekerasan jika dibandingkan dengan responden yang tidak mengalami kecanduan bermain video games yang mengandung unsur kekerasan (67,6%:20,4%) dan terdapat hubungan yang bermakna antara kecanduan bermain video games yang mengandung unsur kekerasan dengan perilaku agresif (p-value=0,000).Disarankan bagi pihak sekolah agar memiliki program konseling psikologis anak misalnya dalam bentuk UKESWA (usaha kesehatan jiwa) yang termasuk dalam program UKS (usaha kesehatan sekolah) untuk mendeteksi sejak dini perilaku kecanduan anak terhadap video games yang mengandung unsur kekerasan dan perilaku agresif anak sehingga dapat diberikan bimbingan untuk mengatasi kecanduan dan perilaku agresif tersebut agar tidak berlanjut dan menjadi conduct disorder atau perilaku anti sosial<br />Kata kunci : agresif, kecanduan, video games</p><p>Abstract<br />Aggressive behavior is a behavior that is intended to harm others to express their negative feelings such as hostility to achieve the desired goal. …”
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16146
Penerapan Model Technology Readiness Index untuk Mengukur Tingkat Kesiapan Mahasiswa dalam Penerimaan Sistem E-Polvot
Published 2023-12-01“…Abstract The Student Executive Board (BEM) plays a pivotal role in governing students and serves as a platform to express aspirations, both in terms of welfare and security, through both oral and written means to the university. …”
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16147
Tecnopolítica, participación electrónica y comunicación digital
Published 2021-03-01“…Frente a un Internet crecientemente privatizado, estos, bajo las lógicas del aprendizaje digital, la privacidad de las comunicaciones, la producción en común, la descentralización y el acceso al conocimiento, expresan una diversidad de maneras de entender y practicar la cultura libre en Internet.…”
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16148
Age-related calcium signaling disturbance restricted cAMP metabolism and induced ovarian oxidation stress in laying ducks
Published 2025-01-01“…Then, according to RNA-Seq analysis, we detected those aged ducks displayed lower Ca concentration in the ovary, while Ca channel related gene expression was increased in GCs to maintain homeostasis. …”
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16149
Exometabolomic exploration of culturable airborne microorganisms from an urban atmosphere
Published 2025-02-01“…Bacteria exhibited proficiency in amino acid synthesis, while fungi were actively involved in amino acid metabolism, transcription, and expression processes. Lipid metabolism, amino acid metabolism, and carbohydrate metabolism varied widely among bacterial strains, while fungi exhibited notable differences in carbohydrate metabolism and secondary metabolism. …”
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16150
Mechanical Activation of cPLA2 Impedes Fatty Acid β‐Oxidation in Vein Grafts
Published 2025-01-01“…Metabolomic analysis showed that a 15%–1 Hz arterial cyclic stretch, compared to a 5%–1 Hz venous stretch, increased long‐chain fatty acids in VSMCs. cPLA2, identified as a mechanoresponsive molecule, produces excessive arachidonic acid (ArAc) under the 15%–1 Hz stretch, inhibiting CPT1B expression, a key enzyme in fatty acid β‐oxidation. …”
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16151
Grain Yield Stability Analysis of Lentil Genotypes by AMMI Indices
Published 2024-11-01“…In addition, to maximize yield and control phenotypic expression, breeders must select specific genotypes that are stable or adapted to a specific environment. …”
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16152
Immunomodulation by allograft endothelial cells
Published 2025-02-01“…It is increasingly appreciated that the expression of immunoregulatory molecules within tumors have potential to shape a microenvironment that promotes local immunoevasion and immunoregulation. …”
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16153
Intranasally administrated fusion-inhibitory lipopeptides block SARS-CoV-2 infection in mice and enable long-term protective immunity
Published 2025-01-01“…Abstract We have assessed antiviral activity and induction of protective immunity of fusion-inhibitory lipopeptides derived from the C-terminal heptad-repeat domain of SARS-CoV-2 spike glycoprotein in transgenic mice expressing human ACE2 (K18-hACE2). The lipopeptides block SARS-CoV-2 infection in cell lines and lung-derived organotypic cultures. …”
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16154
Construction of a rodent neural network-skeletal muscle assembloid that simulate the postnatal development of spinal cord motor neuronal network
Published 2025-01-01“…After coculture with SkM cells, SC-NSCs developed into neural networks (NNs) and exhibited a high proportion of glutamatergic and cholinergic neurons, low proportion of neuroglia and gamma-aminobutyric acidergic neurons, and increased expression of synaptic markers. In NN-SkM assembloids, the acetylcholine receptors of SkM cells were upregulated, generating neuromuscular junction-like structures with NNs. …”
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16155
Elevated Bile Acids Induce Circadian Rhythm Sleep Disorders in Chronic Liver DiseasesSummary
Published 2025-01-01“…Cholemia also blunted the light entrainment response and light-induced phase change of SCN mediated by the neurons expressing gastrin releasing peptide through Tgr5-Per2 axis. …”
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16156
CD21low B cells reveal a unique glycosylation pattern with hypersialylation and hyperfucosylation
Published 2025-02-01“…Additionally, we examined the expression of glycosylation-related genes by RNAseq in naïve-like CD21low B cells ex vivo, as well as in naïve CD21pos B cells from healthy controls after in vitro stimulation.ResultsUnlike CD21pos B cells, naïve-like CD21low B cells from CVID patients and CD21low B cells from healthy controls exhibited a unique glycosylation pattern with high levels of α2,6 sialic acids and fucose. …”
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16157
Preclinical pharmaco-toxicological screening of biomimetic melanin-like nanoparticles as a potential therapeutic strategy for cutaneous melanoma
Published 2025-02-01“…Additionally, MEL-NPs accumulated within the intracellular space of CM cells, forming a perinuclear coating, inhibited their motility and clonogenic potential, increased intracellular oxidative stress, targeted the epithelial-to-mesenchymal transition, and induced apoptosis by altering cell morphology, nuclear aspect, F-actin and tubulin distribution, and by modulating the expression of pro- and anti-apoptotic markers. In ovo, MEL-NPs lacked irritant and vascular toxic effects, while exerting an angio-suppressive activity.ConclusionMEL-NPs demonstrated promising anti-melanoma properties, showing a selective cytotoxicity, a strong anti-invasive effect and a pro-apoptotic activity in CM cells, while inhibiting CAM angiogenesis, these novel findings contributing to future research on the potential application of this nanoplatform in CM therapy.…”
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16158
Evaluation of microRNAs as liquid biopsy markers in adrenocortical tumors
Published 2025-01-01“…Quantitative real-time polymerase chain reaction was employed to analyze microRNA expression.ResultsCirculating levels of miR-483-5p and miR-210 were significantly elevated in patients with active ACC compared to both ACAs (p<0.001 and p=0.004, respectively) and controls (p=0.02 and p = 0.03, respectively). …”
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16159
Development of chimeric Nanobody-Granzyme B functionalized ferritin nanoparticles for precise tumor therapy
Published 2025-03-01“…We also extended similar nanoparticle strategies for gastric cancer therapy, targeting FGFR4-expressing tumor cells. Our findings highlight the potential of engineered nanoparticles as effective and targeted therapeutic agents across various tumor types, offering promising prospects for clinical translation in cancer treatment.…”
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16160
Brief Report: Clinical Characteristics and Outcomes of Patients With Thoracic SMARCA4-Deficient Undifferentiated Tumors
Published 2025-01-01“…Nine (16%) of 55 tumor samples tested had programmed death-ligand 1 expression more than or equal to 50%, with 24 (44%) negative samples. …”
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