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16061
Effect of different dietary oil sources on the performance, egg quality and antioxidant capacity during the late laying period
Published 2025-01-01“…The GSH-PX activity and total antioxidant capacity in the oviducts of the T3 group were significantly higher than those of the T4 group (P < 0.05). The protein expression levels of Nrf2, HO-1, and NQO-1 in the oviduct tissues were significantly higher in the T3 group than in the T4 group (P < 0.05). …”
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16062
The Characteristics Variation of Hepatic Progenitors after TGF-β1-Induced Transition and EGF-Induced Reversion
Published 2016-01-01“…During TGF-β1-induced transition and EGF-induced reversion, hepatic oval cells sustained their progenitor cell marker expression, including α-fetoprotein, albumin, and cytokeratin-19. …”
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16063
TALome and phenotypic analysis of Pakistani Xanthomonas oryzae pv. oryzae population revealed novel virulent TALEs contributing to bacterial blight of rice
Published 2025-01-01“…Interestingly, the expression analysis of six clade-III OsSWEET genes suggests that novel TALE/s targeting unidentified susceptibility gene/s. …”
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16064
Genetic structure and evolutionary diversity of mating-type (MAT) loci in Hypsizygus marmoreus
Published 2021-12-01“…In H. marmoreus, the expression levels of these genes at HD and P/R loci of compatible strains were found higher than in those of homonuclear/homokaryotic strains, indicating that these mating genes acted as switches for mating processes. …”
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16065
Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Valid...
Published 2024-12-01“…We monitored mouse body weight and disease activity index (DAI), and evaluated colon cancer tissues using hematoxylin and eosin staining. Expression of Ki67 and F4/80 was determined by immunohistochemistry analysis. …”
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16066
Ginsenoside F1 administration promotes UCP1-dependent fat browning and ameliorates obesity-associated insulin resistance
Published 2023-11-01“…Using pull down assay and inhibitor interference, we found F1 binds to β3-adrenergic receptors (β3-AR) to enhance UCP1 expression via cAMP/PKA/CREB pathway. We also investigated the ability of F1 on energy metabolism in obesity-induced diabetic mice, including body weight, body composition and energy expenditure. …”
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16067
Study on the Role and Pathological and Immune Responses of Silver Nanoparticles Against Two <i>Aeromonas salmonicida</i> subsp. <i>salmonicida</i> Strains at Different Virulence Le...
Published 2025-01-01“…<i>salmonicida</i> strains (I-1 and I-4), isolated from rainbow trout; the antibacterial mechanism, histopathological alterations and the expression of immune-related genes were investigated. …”
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16068
Russian Science Foundation grant No. 20-14-00140 supported this study. The authors are thankful to the multi-access Center “Bioinformatics” for the use of computational resources a...
Published 2023-01-01“…This evidence suggests that in the past humans carried out selective breeding to reduce the expression of food plant genes encoding these allergenic proteins.…”
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16069
Metabolomics, network pharmacology, and microbiome analyses uncover the mechanisms of the Chinese herbal formula for the improvement of meat quality in spent hens
Published 2025-02-01“…The CHF supplementation increased the glutathione peroxidase level (P < 0.05) and upregulated gene expression related to the Nrf2 pathway (including HO-1, P < 0.05; Nrf2, P = 0.098; CAT, P = 0.060; GPX1, P = 0.063; and SOD2, P = 0.052) and lipid metabolism (including PPARγ, P < 0.05; SREBP1, P = 0.059; and CPT1A, P = 0.058). …”
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16070
PLGA-based biocompatible nanoparticles improved anti-breast tumor efficacy of 1,25(OH)2D3 through the SOCS3/STAT3/EMT signaling axis
Published 2025-03-01“…Considering that epithelial-mesenchymal transition (EMT) is downstream of the SOCS3/STAT3/PI3K pathway, our findings also revealed that 1,25(OH)2D3 markedly regulated the expression of EMT markers. Additionally, the inhibitor of STAT3 exhibited inhibitory effects on EMT progression in breast cancer cells. …”
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16071
Light intensity-dependent arrestin switching for inactivation of a light-sensitive GPCR, bistable opsin
Published 2025-02-01“…In the zebrafish pineal organ, UV sensitive parapinopsin 1 (PP1)-expressing cells exhibit color opponency through photoequilibria between two photo-interconvertible states of PP1. …”
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16072
USP14 inhibition by degrasyn induces YAP1 degradation and suppresses the progression of radioresistant esophageal cancer
Published 2025-02-01“…Methods: To evaluate the expression of USP14 in ESCA tissues or cells, we used RNA-Seq, immunoblotting, co-immunoprecipitation (Co-IP), ubiquitination, quantitative real-time polymerase chain reaction (qRT-PCR), and immunofluorescence assays in this investigation. …”
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16073
Enhanced Oxidative Phosphorylation Driven by TACO1 Mitochondrial Translocation Promotes Stemness and Cisplatin Resistance in Bladder Cancer
Published 2025-02-01“…Clinically, BCa patients with increased mitochondrial TACO1 expression respond poorly to cisplatin treatment. This study elucidates the mechanisms by which TACO1 promotes BCa stemness and cisplatin resistance, providing a potential target for mitigating cisplatin resistance for BCa and a biomarker for predicting cisplatin response.…”
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16074
Microenvironment Influences on Human Umbilical Cord Mesenchymal Stem Cell-Based Bone Regeneration
Published 2021-01-01“…In the in vitro three-dimensional culture microenvironment, nHAC/PLA supported hUC-MSCs’ adhesion, proliferation, and differentiation; the microenvironment containing OMD or OMD and rhBMP-7 shortened cell proliferation progression and made osteogenic differentiation progression advance; rhBMP-7 significantly attenuated the inhibiting effect of OMD on hUC-MSCs’ proliferation and significantly enhanced the promoting effect of OMD on gene expression and protein secretion of osteogenic differentiation markers, calcium and phosphorous concentration, and mineralized matrix formation. …”
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16075
Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence
Published 2025-02-01“…The F. nucleatum genome harbors a conserved ethanolamine utilization (eut) locus with 21 genes that encode several putative BMC shell proteins and a two-component signal transduction system (TCS), in addition to the enzymes for ethanolamine transport and catabolism. We show that the expression of most of these genes and BMC formation are highly increased in wild-type fusobacteria when cultured in the presence of ethanolamine as a nutrient source. …”
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16076
CSF3 promotes colorectal cancer progression by activating p65/NF-κB signaling pathway and inducing an immunosuppressive microenvironment
Published 2025-03-01“…However, the functional importance of CSF3 in colorectal cancer (CRC) remains unclear. Methods: CSF3 expression levels in CRC cells and tissues were detected by quantitative real-time PCR (qRT-PCR), western blot and immunohistochemistry (IHC). …”
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16077
Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2+
Published 2025-01-01“…Cartilage damage was detected by gross observation, micro-CT, and histological analysis. The expression levels of related genes were detected by real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR). …”
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16078
Être enfant à Sfax (Tunisie)
Published 2024-12-01“…Playing, drawing, chatting, filling in forms or weekly reports, handing disposable cameras to the children or taking them on a group walk with commentary can all be used to encourage children to express themselves in different ways.The analysis of this qualitative data is structured in two parts. …”
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16079
High trophic similarity between non-native common carp and gibel carp in Turkish freshwaters: Implications for management
Published 2025-01-01“…The results indicated that common and gibel carp express similar growth types and body conditions in all waters and have similar trophic ecologies. …”
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16080
The analgesic effects of quadratus lumborum block versus caudal block for pediatric patients undergoing abdominal surgery: a systematic review and meta-analysis
Published 2025-02-01“…BackgroundSince children cannot express pain, postoperative pain treatment for them is relatively lacking. …”
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