New insights into the mechanism of triphenyl phosphate and its metabolite diphenyl phosphate in diabetic kidney disease by Ting Fang, Qiaoyan Liu, Xinxin Huangfu, Hongkai Zhu, Hongwen Sun, Liming Chen

“…The study also detected mRNA expression of core targets molecularly docked with TPHP and DPHP using real-time-PCR. …”
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Ochratoxin A induces immunotoxicity by targeting Annexin A1 mediated neutrophil apoptosis in zebrafish by Yihong Zheng, Yinuo Liu, Jin Tian, Shuhong Liu, Gaowei Ma, Yupeng Xie, Chenhua Zheng, Zekai Wu

“…Transcriptome sequencing analysis was performed to identify changes in gene expression. Additionally, the potential therapeutic effect of aesculetin was evaluated.ResultsOur results demonstrated that exposure to OTA inhibited embryonic development and induced malformations in a concentration-dependent manner. …”
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Intraindividual variation in histone acetylation and its impact on autoimmune thyroid diseases by Emi Haga, Naoya Inoue, Yoshinori Iwatani, Yuya Arakawa, Emi Morita, Hidemi Hashimoto, Yusuke Noguchi, Yoh Hidaka, Mikio Watanabe

“…Histone acetylation, especially that of histone H3, is an epigenetic mechanism that regulates gene expression and is associated with the development of autoimmune diseases. …”
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Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease by Long Fung Chau, Simon Lillico, Tanja Opriessnig, Rosemary Blake, Luc Tardy, Chen-Hsuin Lee, Scott Maxwell, Claire Warren, Elizabeth Thornton, Catherine L. Mclaughlin, Gerry McLachlan, Christine Tait-Burkard, Sarah Fletcher, Stephen Anderson, Sharon Brown, Louise Gibbard, Thomas Tzelos, Dawn MacMillan-Christensen, J. Kenneth Baillie, David A. Dorward, David J. Griffiths, Finn Grey

“…To address this, we have developed transgenic pigs expressing human ACE2 that are susceptible to SARS-CoV-2 infection. …”
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KULTŪRINIO IR SIMBOLINIO KAPITALO GAMYBA: "DISNEY" FENOMENAS by Gintautas Mažeikis

“…Benjamin's views where Disney's corporation is considered as an expression of hegemonic industrial imperialism and a propagandist of American ideology.  …”
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Gedunin Mitigates <i>Cutibacterium acnes</i>-Induced Skin Inflammation by Inhibiting the NF-κB Pathway by Ju Kyoung Sim, Ye Ji Heo, Jin Hak Shin, Seon Sook Kim, Su Ryeon Seo

“…<b>Results</b>: Gedunin significantly reduced the expression of IL-1β, TNF-α, iNOS, COX-2, and IL-6 in RAW 264.7 cells. …”
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PNPO‐Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β‐Catenin Pathway by Zhendong Deng, Shanliang Sun, Nian Zhou, Yumeng Peng, Long Cheng, Xichao Yu, Yuxia Yuan, Mengjie Guo, Min Xu, Yuexin Cheng, Fan Zhou, Nianguang Li, Ye Yang, Chunyan Gu

“…Abstract Multiple myeloma (MM) is a cancer of plasma cells caused by abnormal gene expression and interactions within the bone marrow (BM) niche. …”
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Glycyrrhizinate Monoammonium Cysteine-Loaded Lipid Nanoparticles Allow for Improved Acute Liver Injury Therapy by Yunjie Xu, Pinghui Li, Shiran Sun, Yulin Chen, Lixia Feng, Dawei Jiang, Chidan Wan, Jianbo Li, Xiong Cai

“…This study also explores the expression of fibroblast activation protein (FAP) in ALI, employing ⁶⁸Ga-FAPI PET/CT imaging for effective differentiation and assessment of liver injury. …”
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Male Central Precocious Puberty: Serum Profile of Anti-Müllerian Hormone and Inhibin B before, during, and after Treatment with GnRH Analogue by Romina P. Grinspon, Luz Andreone, Patricia Bedecarrás, María Gabriela Ropelato, Rodolfo A. Rey, Stella M. Campo, Ignacio Bergadá

“…In conclusion, AMH did not decrease in patients <1 yr reflecting the lack of androgen receptor expression in Sertoli cells in early infancy. Serum inhibin B might result from the contribution of two sources: the mass of Sertoli cells and the stimulation exerted by FSH. …”
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Fish Scale-Derived Scaffolds for Culturing Human Corneal Endothelial Cells by Mohit Parekh, Bert Van den Bogerd, Nadia Zakaria, Diego Ponzin, Stefano Ferrari

“…Proliferative cells were detected in both conditions (4.6% in Lab-Tek versus 4.2% in FSS; p=0.5922). Vinculin expression was marginally higher in HCEnCs cultured on Lab-Tek (234 versus 199 focal adhesions; p=0.0507). …”
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A covalent peptide-based lysosome-targeting protein degradation platform for cancer immunotherapy by Youmei Xiao, Zhuoying He, Wanqiong Li, Danhong Chen, Xiaoshuang Niu, Xin Yang, Wenxuan Zeng, Mengfan Wang, Yuzhen Qian, Ye Su, Feiyu Luo, Guanyu Chen, Juan Liu, Xinghua Sui, Xiuman Zhou, Yanfeng Gao

“…Biological experiments demonstrate that covalent Pep-TACs can significantly degrade the expression of PD-L1 on tumor cells, dendritic cells and macrophages, especially under acidic conditions, and markedly enhance the function of T cells and tumor phagocytosis by macrophages. …”
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Assessment of Arf6 Deletion in PLB-985 Differentiated in Neutrophil-Like Cells and in Mouse Neutrophils: Impact on Adhesion and Migration by Jouda Gamara, Lynn Davis, Emmanuelle Rollet-Labelle, Tsunaki Hongu, Yuji Funakoshi, Yasunori Kanaho, Fawzi Aoudjit, Sylvain G. Bourgoin

“…Impaired cell migration correlated with reduced cell surface expression of CD11a and CD11b in Arf6 cKO PMNs. Our results highlight that Arf6 regulates the activity and possibly the recycling of PMN integrins, and this compromises PMN migration to inflammatory sites.…”
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Clinical characteristics, metastasis patterns, and treatment outcomes of HER2-low breast cancer by Maria Elena Lacruz, Saskia Thies, Andrea Schmidt-Pokrzywniak, Ian Wittenberg, Tobias Engler, Fabian Reinwald, Monika Klinkhammer-Schalke, Sylke Ruth Zeissig, Bianca Franke, Kerstin Weitmann, Atanas Ignatov

“…HER2-low, characterized by low HER2 expression without gene amplification, recently gained attention. …”
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Integration of clinical, pathological, radiological, and transcriptomic data improves prediction for first-line immunotherapy outcome in metastatic non-small cell lung cancer by Nicolas Captier, Marvin Lerousseau, Fanny Orlhac, Narinée Hovhannisyan-Baghdasarian, Marie Luporsi, Erwin Woff, Sarah Lagha, Paulette Salamoun Feghali, Christine Lonjou, Clément Beaulaton, Andrei Zinovyev, Hélène Salmon, Thomas Walter, Irène Buvat, Nicolas Girard, Emmanuel Barillot

“…Testing multiple integration strategies, most of them yield multimodal models surpassing both the best unimodal models and established univariate biomarkers, such as PD-L1 expression. Additionally, several multimodal combinations demonstrate improved patient risk stratification compared to models built with routine clinical features only. …”
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Environmental microbial communications in gram-positive and gram-negative bacteria by P. Srikanth, D. Sivakumar, J. Nouri

“…The concentration of these signalling substances rises above a critical level when the population density does, causing particular gene expression patterns in the microorganisms. This may result in coordinated behaviours, including the development of biofilms, the generation of virulence factors, or other group activities. …”
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Foreword

“…Finally, JEONG Eun Kyung’s “A Comparative Study of Idiomatic Expressions Related to Staple Foods in Korea and Türkiye: Rice and Bread” bridges linguistic and cultural divides, comparing idiomatic expressions tied to staple foods in Korean and Turkish traditions. …”
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Transcriptome datasets of salt-stressed tomato plants treated with zinc oxide nanoparticlesMendeley DataSRR30014447 - SRR30014450SRR30014447 - SRR30014450PRJNA1141123SRR30014447 -... by Mostafa Ahmed, Zoltán Tóth, Diaa Attia Marrez, Roquia Rizk, Donia Abdul-Hamid, Kincső Decsi

“…Moving forward, the utilization of databases will facilitate the examination of modifications in plant biochemical reactions at the level of gene expression.…”
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A case of de novo neuroendocrine prostate cancer presented with elevated level of serum CEA carrying BRCA2 mutation: case report and literature review by Weizhe Han, Nihati Rexiati, Fang Yu, Yongzhi Wang, Yueli Tian, Jianyuan Wu, Gang Wang, Tao Liu, Zhonghua Yang

“…Immunohistochemistry (IHC) staining and next generation sequencing demonstrated a strong expression of chromogranin A (CgA), synaptophysin (SYN) and CEA, and a germline mutation in BRCA2, respectively. …”
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Establishment and Clinical Application of Rh Blood Group Bank in the East China Region by Jin Y, Fu X, Xie S, Liu Z, Xu Z, Wang M, Wang Y, Lu R, Wang L

“…Yiming Jin,1,&ast; Xiaoyan Fu,2,&ast; Shuhong Xie,3 Zhen Liu,1 Zihao Xu,1 Mingyuan Wang,1 Yihan Wang,1 Rong Lu,1 Lingling Wang1 1Department of Blood Screening Test, Suzhou Blood Center, Suzhou, People’s Republic of China; 2Department of Blood Screening Test, Tai Cang Blood Branch Station, Tai Cang, People’s Republic of China; 3Division of Transfusion Medicine, Suzhou Blood Center, Suzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Lingling Wang; Rong Lu, Department of Blood Screening Test, Suzhou Blood Center, Suzhou, People’s Republic of China, Email linglingwang0716@163.com; cv-25a@163.comPurpose: To investigate the expression and distribution of Rh phenotypes (C, c, D, E, e) among voluntary blood donors in a specific region of East China, to establish a regional Rh phenotype database, and to enhance the precision and efficacy of clinical blood transfusions.Patients and Methods: A total of 28979 blood samples were collected from voluntary donors at a central blood station in East China between May 2023 and December 2023. …”
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Local Application of Semaphorin 3A Combined with Adipose-Derived Stem Cell Sheet and Anorganic Bovine Bone Granules Enhances Bone Regeneration in Type 2 Diabetes Mellitus Rats by Xiaoru Xu, Kaixiu Fang, Lifeng Wang, Xiangwei Liu, Yuchao Zhou, Yingliang Song

“…The rat ASC sheets showed stronger osteogenic ability than ASCs in vitro, as indicated by the extracellular matrix mineralization and the expression of osteogenesis-related genes at mRNA level. …”
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