Environmental Challenges Faced by a Kindergarten and a School in the Katima Mulilo Education Circuit by Давид Нкенгбеза, Мундія Кілібоні Еустінах, Євген Літаба Маемеко, Муквамбо Музва

“…This method is appropriate for this study because participants were required to share their perspectives and express their thoughts about their school environment, allowing researchers to gather detailed experiences and feedback from the population. …”
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The Role of Invariant NKT in Autoimmune Liver Disease: Can Vitamin D Act as an Immunomodulator? by Daniel S. Smyk, Athanasios Mavropoulos, Giorgina Mieli-Vergani, Diego Vergani, Marco Lenzi, Dimitrios P. Bogdanos

“…Natural killer T (NKT) cells are a distinct lineage of T cells which express both the T cell receptor (TCR) and natural killer (NK) cell markers. …”
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A Cost-Effective and Robust Cell-Based Bioassay Method for Evaluating the Bioactivity of Trastuzumab-like Antibodies by Pooja Bharali, Subhash Chand, Harish Chander

“…<b>Results:</b> The SKBR3 cell line was found to express the HER2 receptors significantly higher in comparison to the other cell lines, and it was thereby selected for further bioassay optimization. …”
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Modern trends in breeding and genetic improvement of sunflower varieties and hybrids at VNIIMK by V. M. Lukomets, M. V. Trunovа, Ya. N. Demurin

“…For Clearfield technology, the hybrids Imidzh, Arimi and Immi have been developed; for Clearfield Plus, the hybrid Klip; and for Express Sun (or SUMO), the hybrid Surus. Klip and Surus are mid-oleic. …”
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Study on Acoustic Emission Characteristics and Mechanical Behavior of Water-Saturated Coal by Muhammad Ali, Enyuan Wang, Zhonghui Li, Haishan Jia, Dexing Li, Izhar Mithal Jiskani, Barkat Ullah

“…AE signals were continuously monitored during loading to examine the AE characteristic response via the AEwin Express-8.0 system. The results revealed that the mechanical characteristics of the coal samples decreased with an increase in soaking time. …”
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A study of macroinvertebrate communities in Bolshiye Koty Bay of Lake Baikal using DNA metabarcoding by L. S. Kravtsova, T. E. Peretolchina, T. I. Triboy, I. A. Nebesnykh, A. E. Tupikin, M. R. Kabilov

“…The approach proposed for studying the structure of macroinvertebrate communities based on DNA metabarcoding and next generation sequencing can be recommended for express assessment of the state of aquatic ecosystems in the monitoring.…”
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Sustainable human resource management practices in organizational performance: The mediating impacts of knowledge management and work engagement by Shatha Abu-Mahfouz, Mutia Sobihah Abd Halim, Ayu Suriawaty Bahkia, Noryati Alias, Ph.D. in Management, Abdul Malek Tambi

“…Human resource management (HRM) practices give sustainable opportunities for employees to use their abilities and express their enthusiasm to obtain skills and knowledge and to apply them at the workplace with a view to achieving engaged individuals and increasing organizational performance. …”
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Anaplastic Thyroid Carcinoma: A ceRNA Analysis Pointed to a Crosstalk between SOX2, TP53, and microRNA Biogenesis by Walter Arancio, Valeria Carina, Giuseppe Pizzolanti, Laura Tomasello, Maria Pitrone, Concetta Baiamonte, Marco Calogero Amato, Carla Giordano

“…In detail, silencing SOX2 in SW1736 is able to suppress the expression of the stem markers analysed, strongly sensitizing the line to treatment with chemotherapeutic agents. …”
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Effect of Cd–Zn compound contamination on the physiological response of broad bean and aphids by Liya Chen, Sijing Wan, Qintian Shen, Keting Zhao, Yanlan He, Yexin Xie, Shiyu Tao, Shuchang Zheng, Yi Zhang, Shigui Wang, Bin Tang, Yan Li, Yan Li

“…In addition, in the first generation of adult aphids, treatment with Cd (12.5 mg/kg) + Zn (100 mg/kg) significantly affected the expression of trehalase (TRE) and trehalose-6-phosphate synthase (TPS) genes and influenced the carbohydrate content and trehalase activity in the aphids.DiscussionThe number of offspring produced by the second-generation aphids was significantly reduced under mixed heavy metal treatment, but it was not caused by changes in the vitellogenin (Vg) content. …”
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Proinflammatory Cytokines IL-6 and TNF-α Increased Telomerase Activity through NF-κB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells by Seyung S. Chung, Yong Wu, Quincy Okobi, Debbie Adekoya, Mohammad Atefi, Orette Clarke, Pranabananda Dutta, Jaydutt V. Vadgama

“…Notably, withaferin A inhibited STAT3 phosphorylation and abolished the STAT3, STAT1, and NF-κB interactions. Oct-4 expression was also downregulated by withaferin A inhibition. …”
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The <i>Meq</i> Genes of Nigerian Marek’s Disease Virus (MDV) Field Isolates Contain Mutations Common to Both European and US High Virulence Strains by Joseph N. Patria, Luka Jwander, Ifeoma Mbachu, Levi Parcells, Brian Ladman, Jakob Trimpert, Benedikt B. Kaufer, Phaedra Tavlarides-Hontz, Mark S. Parcells

“…Several of the <i>meq</i> genes were cloned for expression and their localization ability to interact with the chicken NF-IL3 protein, a putative Meq dimerization partner, were assessed. …”
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What is the relationship between exposure to environmental pollutants and severe mental disorders? A systematic review on shared biological pathways by Pierluigi Catapano, Mario Luciano, Salvatore Cipolla, Daniela D'Amico, Alessandra Cirino, Maria Chiara Della Corte, Gaia Sampogna, Andrea Fiorillo

“…The biological mechanisms by which environmental pollution and climate change influence the onset and exacerbation of severe mental disorders are complex and include gene expression, inflammation, oxidative stress, and anatomical brain changes. …”
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RfxCas13d-mediated inhibition of Circ1647 alleviates renal fibrosis via PI3K/AKT signaling pathway by Yufang Ni, Hongmin Zhang, Qianwen Xian, Wenjie Qin, Hongwei Su, Li Wang, Jianchun Li

“…In addition, overexpressing of Circ1647 in renal tubular epithelial cells (TCMK1) was performed to investigate the underlying mechanisms of Circ1647.Results Our results displayed that electroporation-mediated knockdown of Circ1647 by RfxCas13d knockdown plasmid significantly inhibited renal fibrosis in UUO mice as evidenced by reduced expression of fibronectin and α-SMA (alpha-smooth muscle actin). …”
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[18F]Tetrafluoroborate, a new NIS PET/CT radiopharmaceutical: an overview focused on differentiated thyroid cancer by Arnoldo Piccardo, Francesco Fiz, Sergio Righi, Stefano Raffa, Mattia Riondato, Gianluca Bottoni, Matteo Bauckneht, Michela Massollo, Alessio Rizzo, Mehrdad Shoushtari Zadeh Naseri, Pierpaolo Trimboli, Giorgio Treglia

“…Background: In relapsing differentiated thyroid cancer (DTC), the in vivo evaluation of natrium–iodide symporter (NIS) expression is pivotal in the therapeutic planning and is achieved by 131/123Iodine (131/123I) whole body scan. …”
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Increased Growth Differentiation Factor 15 Levels Are Associated with HIV-Associated Neurocognitive Impairment: A Pilot Study by Ali Boustani, Mary K. Ford, Jacqueline R. Kulbe, Anna E. Laird, Leeann Shu, Matthew Spencer, Bryant Avalos, Kyle C. Walter, Ronald J. Ellis, Jerel Adam Fields

“…This study investigates the relationship between GDF15 expression and HIV-associated NCI. <b>Methods</b>: PWH from the California NeuroAIDS Tissue Network (CNTN) underwent comprehensive neuropsychological exams within 12 months before death and were categorized based on cognitive performance. …”
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A next-generation Fab library platform directly yielding drug-like antibodies with high affinity, diversity, and developability by Fortunato Ferrara, Adeline Fanni, Andre A. R. Teixeira, Esteban Molina, Camila Leal-Lopes, Ashley DeAguero, Sara D’Angelo, M. Frank Erasmus, Laura Spector, Luis Antonio Rodriguez Carnero, Jianquan Li, Thomas J. Pohl, Nikolai Suslov, Klervi Desrumeaux, Conor McMahon, Sagar Kathuria, Andrew R. M. Bradbury

“…The scFab single-gene format provides balanced expression of light and heavy chains, with enhanced conversion to IgG, thereby combining the advantages of scFvs and Fabs. …”
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Lymphatic-derived oxysterols promote anti-tumor immunity and response to immunotherapy in melanoma by Mengzhu Sun, Laure Garnier, Romane Chevalier, Martin Roumain, Chen Wang, Julien Angelillo, Julien Montorfani, Robert Pick, Dale Brighouse, Nadine Fournier, David Tarussio, Stéphanie Tissot, Jean-Marc Lobaccaro, Tatiana V. Petrova, Camilla Jandus, Daniel E. Speiser, Manfred Kopf, Caroline Pot, Christoph Scheiermann, Krisztian Homicsko, Giulio G. Muccioli, Abhishek D. Garg, Stéphanie Hugues

“…In human melanoma, LECs also upregulate Ch25h, and its expression correlates with the lymphatic vessel signature, infiltration of pro-inflammatory macrophages, better patient survival, and better response to immunotherapy. …”
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Ningxiang pig-derived lactobacillus reuteri modulates host intramuscular fat deposition via branched-chain amino acid metabolism by Mei Yang, Qian Xie, Jing Wang, Andong Zha, Jiashun Chen, Qian Jiang, Meng Kang, Qiuchun Deng, Yulong Yin, Bie Tan

“…Additionally, it has been verified that L. reuteri originating from NX pigs has the ability to improve BCAA synthesis in the gut and enhance IMF content in lean DLY pigs. The expression of genes related to lipid synthesis was also significantly upregulated. …”
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Identification of potential substrates of LNX1 in chicken cells by Yuhong Liu, Qianmei Gao, Qi Zhang, Chen Li, Sha Liu, Meng Su, Danli Song, Guiping Zhao, Qinghe Li

“…This identified 319 proteins with up-regulated expression, a majority of which relate to the immune system. …”
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Development of a Cell-Based High-Throughput Screening Assay to Identify Porcine Host Defense Peptide-Inducing Compounds by Zhuo Deng, Jing Wang, Wentao Lyu, Xuwen Wieneke, Robert Matts, Xi Ma, Guolong Zhang

“…Eight compounds were subsequently observed to be comparable to sodium butyrate in inducing PBD3 mRNA expression in parental IPEC-J2 cells in the low micromolar range. …”
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