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  1. 14981

    Association of The MCP-1 rs1024611 Polymorphism with Polycystic Ovary Syndrome in A Population of Indian Women: A Case-Control Study by Jijo Francis, Honey Sebastian, Saley Daniel, Leyon Varghese, Sareena Gilvaz, Ragitha Thenkattil Sankarankutty, Siji Susan George, Pulikkottil Raphael Varghese, Suresh Kumar Raveendran

    Published 2025-01-01
    “…Genetic variations in the MCP-1 gene may modulate MCP-1 expression. Although the association of theMCP-1 promoter polymorphism (-2518A/G) was extensively studied in different inflammatory conditions, there isonly one report in PCOS conditions. …”
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  2. 14982

    Establishing trust through home visits during pregnancy: a realist evaluation of a Danish breastfeeding support intervention by Anne Kristine Gadeberg, Ingrid Maria Susanne Nilsson, Ulla Christensen, Marie Honoré Jacobsen, Henriette Knold Rossau, Sarah Fredsted Villadsen

    Published 2025-01-01
    “…The mechanism resulted in improved tailored breastfeeding support postpartum, families reaching out to the health visitor sooner when experiencing breastfeeding difficulties, and families expressing a more positive experience of breastfeeding. …”
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  3. 14983

    Insecticide resistant Anopheles from Ethiopia but not Burkina Faso show a microbiota composition shift upon insecticide exposure by Netsanet Worku, Antoine Sanou, Juliane Hartke, Marion Morris, Fatoumata Cissé, Salimata Ouédraogo, Madou Tapsoba, Nicola Vallon, Tewodros Debebe Akilu, Ligabaw Worku, Moussa Wamdaogo Guelbeogo, Victoria A. Ingham

    Published 2025-01-01
    “…To further understand resistance in this An. arabiensis population, we performed RNAseq and saw differential expression of detoxification genes associated with insecticide resistance and changes in respiration, metabolism and synapse-related ion channels. …”
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  4. 14984

    A Novel Spontaneous Mutation of the SOX10 Gene Associated with Waardenburg Syndrome Type II by Sen Chen, Yuan Jin, Le Xie, Wen Xie, Kai Xu, Yue Qiu, Xue Bai, Hui-Min Zhang, Xiao-Zhou Liu, Xiao-Hui Wang, Wei-Jia Kong, Yu Sun

    Published 2020-01-01
    “…Therefore, this truncated protein may fail to activate the expression of the MITF gene, which regulates melanocytic development and plays a key role in WS. …”
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    Article
  5. 14985

    A single-nucleus RNA sequencing atlas of the postnatal retina of the shark Scyliorhinus canicula by Nicolás Vidal-Vázquez, Ismael Hernández-Núñez, Pablo Carballo-Pacoret, Sarah Salisbury, Paula R. Villamayor, Francisca Hervas-Sotomayor, Xuefei Yuan, Francesco Lamanna, Céline Schneider, Julia Schmidt, Sylvie Mazan, Henrik Kaessmann, Fátima Adrio, Diego Robledo, Antón Barreiro-Iglesias, Eva Candal

    Published 2025-02-01
    “…Here, we present a single-nucleus RNA sequencing atlas of the postnatal retina of the catshark Scyliorhinus canicula, consisting of the expression profiles for 17,438 individual cells from three female, juvenile catshark specimens. …”
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    Article
  6. 14986

    Concatenated Vertical Channel Modeling and Performance Analysis for HAP-Based Optical Networks by Neha Tiwari, Swades De, Dharmaraja Selvamuthu

    Published 2024-01-01
    “…Next, a closed-form expression for the probability density function is developed for the concatenated channel incorporating a generalized pointing error model. …”
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    Article
  7. 14987

    Immunogenicity of HIV-1 <i>Env</i> mRNA and <i>Env-Gag</i> VLP mRNA Vaccines in Mice by Qi Ma, Jing Yang, Xiaoguang Zhang, Hongxia Li, Yanzhe Hao, Xia Feng

    Published 2025-01-01
    “…Methods: We constructed nucleotide-modified mRNA vaccines expressing HIV-1 Env and Gag proteins. Env–gag virus-like particles (VLPs) were generated through co-transfection with env and gag mRNA vaccines. …”
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    Article
  8. 14988

    Anti-allergic effect of 5,7-dihydroxy-4-methylcoumarin in IgE-mediated RBL-2H3 cells and PCA murine model by Sugeun Gwon, Seong-Ah Shin, Moonsu Kim, Sun Young Moon, Seyeon Choi, Minji Kim, Jun Hyuck Lee, Hyun Ho Park, Chang Sup Lee

    Published 2025-01-01
    “…Our findings demonstrated that 5,7-dihydroxy-4-methylcoumarin reduced the release of histamine and β-hexosaminidase and downregulated the mRNA expression of allergic-inflammatory cytokines, such as interleukin (IL)-4, IL-13, and tumor necrosis factor-alpha, as well as the inflammatory enzyme cyclooxygenase-2. …”
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    Article
  9. 14989

    Serum CXCL12 and S100A12 levels in peripheral blood fluid and their correlation with severity in patients with knee osteoarthritis by LijiangTao, Minjuan He, Yisheng Lu, Jie Zheng, Yili Ye

    Published 2025-01-01
    “…Background: This paper aimed to investigate the expression of CXCL12 and S100A12 in peripheral blood (PB) and synovial fluid (SF) of patients with knee osteoarthritis (OS) and to analyze the correlation between them and the severity of knee OS. …”
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  10. 14990

    Formulated citrus peel extract gold lotion improves cognitive and functional recovery from traumatic brain injury (TBI) in rats by Cheng Guang, Yue Zhiwei, Wang Liwen, Miyauchi Yutaka, Suzawa Michiko, Li Shiming, Ho Chi‐Tang, Zhao Hui, Chen Naiyao

    Published 2020-09-01
    “…The mechanisms probably due to that GL could not only reduce the associated damage markers including GFAP, OX-42, TNF-α, COX-2, NF-κB and TLR4 but also promote the expression of VEGF which is responsible for protecting neuronal cells in the injury area. …”
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    Article
  11. 14991

    Molecular Network Associated with MITF in Skin Melanoma Development and Progression by Ichiro Yajima, Mayuko Y. Kumasaka, Nguyen Dinh Thang, Yuji Goto, Kozue Takeda, Machiko Iida, Nobutaka Ohgami, Haruka Tamura, Osamu Yamanoshita, Yoshiyuki Kawamoto, Keiko Furukawa, Masashi Kato

    Published 2011-01-01
    “…These first triggers alter the conditions of numerous genes and proteins, and they induce and/or reduce gene expression and activate and/or repress protein stability and activity, resulting in melanoma progression. …”
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    Article
  12. 14992

    Cyclic Peptides as Protein Kinase Modulators and Their Involvement in the Treatment of Diverse Human Diseases by Lorena Martínez-Alcantar, Laura Hernández-Padilla, Alma Laura Díaz-Pérez, Lizbeth Guadalupe Villalón-Magallán, Mayra Xóchitl Durán-Maldonado, César Díaz-Pérez, Marlene E. Campos-Morales, Citlali Figueroa-Guzmán, Jesús Campos-García

    Published 2024-12-01
    “…Nevertheless, modifications in the expression due to mutations or their dysregulation can lead to diseases, including autoimmune disorders, cardiovascular problems, diabetes, neurological diseases, and cancers. …”
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  13. 14993
  14. 14994
  15. 14995

    Strontium Promotes the Proliferation and Osteogenic Differentiation of Human Placental Decidual Basalis- and Bone Marrow-Derived MSCs in a Dose-Dependent Manner by Yi-Zhou Huang, Cheng-Guang Wu, Hui-Qi Xie, Zhao-Yang Li, Antonietta Silini, Ornella Parolini, Yi Wu, Li Deng, Yong-Can Huang

    Published 2019-01-01
    “…By contrast, 10 mM strontium facilitated the osteogenic gene expression as well as the mineralization of human PDB- and BM-MSCs. …”
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    Article
  16. 14996

    The Role of Cholesterol during the Ovarian Maturation and Lipid Metabolism of Female Chinese Mitten Crab (Eriocheir sinensis) by Huixing Guo, Haokun Hua, Jianfeng Wang, Wei Qiang, Xiaoe Xiang, Wenbin Liu, Guangzhen Jiang

    Published 2024-01-01
    “…Through the analysis of mRNA expression level of genes related to lipid metabolism, it was found that cholesterol enhanced the transcription level of genes related to lipid synthesis and transport in hepatopancreas, thereby promoting the accumulation of lipid in the organism. …”
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    Article
  17. 14997

    Hyperglycemia Does Not Affect Iron Mediated Toxicity of Cultured Endothelial and Renal Tubular Epithelial Cells: Influence of L-Carnosine by Shiqi Zhang, Emmanouil Ntasis, Sarah Kabtni, Jaap van den Born, Gerjan Navis, Stephan J. L. Bakker, Bernhard K. Krämer, Benito A. Yard, Sibylle J. Hauske

    Published 2016-01-01
    “…HG did not change the expression of divalent metal transporter 1 (DMT1), ferroportin (IREG), and transferrin receptor protein 1 (TFRC). …”
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  18. 14998

    THE STORY OF DISTURBANCE IN THE QUR’AN: A STUDY OF THE TAFSIR AL-MISHBAH BY M. QURAISH SHIHAB by Febri Wardani, Roihatul Jannah Siagian, Muhammad Rizqi

    Published 2023-12-01
    “…Allah provides solutions to the Prophet and pious people in the Qur’an in various forms of expression. However, it is focused on one point: drawing closer to Allah and keeping away things that can damage the heart from envy and other bad qualities.…”
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  19. 14999

    Determination of Mammalian Target of Rapamycin Hyperactivation as Prognostic Factor in Well-Differentiated Neuroendocrine Tumors by G. Lamberti, C. Ceccarelli, N. Brighi, I. Maggio, D. Santini, C. Mosconi, C. Ricci, G. Biasco, D. Campana

    Published 2017-01-01
    “…To evaluate the role of the activation of mTOR (phosphorylated mTOR, p-mTOR) and the expression SSTR2A and IGF-1R as prognostic factor in well-differentiated neuroendocrine tumors. …”
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    Article
  20. 15000