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14541
Bender–Knuth Billiards in Coxeter Groups
Published 2025-01-01“…When W is finite, we actually prove that if $s_{i_N}\cdots s_{i_1}$ is a reduced expression for the long element of W, then $\tau _{i_N}\cdots \tau _{i_1}(W)=\mathscr {L}$ ; this allows us to determine the smallest integer $\mathrm {M}(c)$ such that $\mathrm {Pro}_c^{{\mathrm {M}}(c)}(W)=\mathscr {L}$ for all $\mathscr {L}$ . …”
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14542
CircWDR78 inhibits the development of colorectal cancer by regulating the miR-653-3p/RGS4 axis
Published 2025-02-01“…Results This study demonstrated that circWDR78 is lower expression in colorectal cancer tissues, revealing its capacity to inhibit proliferation, colony forming ability and cell motility. …”
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14543
Comprehensive single-cell pan-cancer atlas unveils IFI30+ macrophages as key modulators of intra-tumoral immune dynamics
Published 2025-01-01“…Substantiated by single-cell analysis, IFI30 exhibits significant functional enrichment in immune-related pathways. Co-expression with immune-related genes, including MHC elements and immune checkpoints, further validates its relevance.ConclusionOur study positions IFI30 as a promising immunotherapeutic target. …”
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14544
Comparative Investigation of Human Amniotic Epithelial Cells and Mesenchymal Stem Cells for Application in Bone Tissue Engineering
Published 2015-01-01“…Microarray analysis revealed a different expression profile of genes involved in ossification along the three cell sources, highlighting the impact of different anatomical origin and molecular response to osteogenic induction on the final tissue-forming potential. …”
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14545
Hydroxytyrosol Protects against Myocardial Ischemia/Reperfusion Injury through a PI3K/Akt-Dependent Mechanism
Published 2016-01-01“…Myocardial infarct size, markers of oxidative stress, extent of myocardial apoptosis, echocardiographically assessed cardiac function, and expression of Akt and GSK 3β were measured in each group. …”
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14546
Localization of Liv2 as an Immature Hepatocyte Marker in EB Outgrowth
Published 2009-01-01“…The objective of this study was to establish Liv2, a surface marker of mouse immature hepatocytes (hepatoblasts), as a selection tool for embryonic stem (ES) cell–derived immature hepatocytes by acquiring basic data on Liv2 in normal mouse embryos and by confirming Liv2 expression in mouse ES-derived cells. The estimated molecular weight of Liv2 was 4045 kDa, and immunoreactivity was definitively detected in the cell membrane of fetal hepatocytes on embryonic day (E) 9.5, declined gradually until E12.5, and subsequently became undetectable. …”
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14547
CHST1 as a prognostic-related biomarker in gastric cancer correlating with immune infiltration
Published 2025-02-01“…Furthermore, we constructed a co-expression network of CHST1 and explored its relationship with clinicopathological features, the tumor microenvironment, and immune infiltration through bioinformatics analysis. …”
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14548
Crop protection by RNA interference: a review of recent approaches, current state of developments and use as of 2013
Published 2025-01-01“…Abstract RNAi-based applications aim to inhibit the expression of specific essential genes in target organisms by uptake and processing of double-stranded RNA and subsequent degradation of target gene mRNA. …”
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14549
The neuroendocrine stress-response in insects: the history of the development of the concept
Published 2017-12-01“…The duration and the expression of each stage can vary depending on the nature and strength of the stressor agent, the species of the animal and the physiological state of the organism. …”
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14550
In vitro immunomodulatory effects of thymol and cinnamaldehyde in a pig intestinal epithelial cell line (IPEC-J2)
Published 2020-11-01“…Cytotoxicity, permeability, wound-healing and bacteria adhesion assays were recorded. The expression of cytokines, tight junctions and polymeric immunoglobulin receptor (pIgR) were measured by RT-PCR. …”
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14551
Heterogeneous focal adhesion cytoskeleton nanoarchitectures from microengineered interfacial curvature to oversee nuclear remodeling and mechanotransduction of mesenchymal stem cel...
Published 2025-01-01“…Immunofluorescent staining of integrin, vinculin, and talin-1 was conducted to evaluate adhesion-related expression levels. Then, immunofluorescent staining of actin, actinin, and myosin was performed to detect cytoskeleton distribution, especially at the periphery. …”
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14552
Characterizing tertiary lymphoid structures associated single-cell atlas in breast cancer patients
Published 2025-01-01“…We identified eighteen cell types within the TLS associated regions and calculated differential expression genes by comparing TLS associated regions with other areas. …”
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14553
L-arabinose alleviates constipation through gastrointestinal peptide,gut microbiota,and Phlpp2 of gastrointestinal rhythms in rats
Published 2025-02-01“…It also upregulated the expression of Cd38, Phlpp2, Muc3, and Acat2, while downregulating Cd34, C1qa, and C1qc. …”
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14554
Formononetin ameliorates polycystic ovary syndrome through suppressing NLRP3 inflammasome
Published 2025-01-01“…Besides, the function of FMN on cell viability and apoptosis in DHT-induced PCOS cell model were explored by using CCK-8 assay and flow cytometry. Protein expression was detected via western blot and immunofluorescence staining in the DHEA-induced PCOS rat model and DHT-induced PCOS cell model. …”
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14555
Effectiveness of Retail Promotions in the Green Industry by Age Group: A Case Study
Published 2020-03-01“…Interestingly, young consumers are also expressing interest in gardening. In 2012, Millennials (born after 1980) spent 78% more on gardening purchases than in the previous 2 years. …”
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14556
Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway
Published 2020-01-01“…MTX-induced inflammatory effects are evidenced by the increased cardiac toll-like receptor 4 (TLR4) mRNA expression and protein level as well as increased cardiac tumor necrosis factor- (TNF-) α and interleukin- (IL-) 6 levels along with increased nuclear factor- (NF-) κB/p65 immunostaining. …”
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14557
The role of interleukin-17 in inflammation-related cancers
Published 2025-01-01“…In this review, we introduce the fundamental biology of IL-17 and the expression profile of its receptors in cancer, while also reviewing and discussing recent advancements regarding the pleiotropic effects and mechanisms of IL-17 in inflammation-related cancers. …”
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14558
Efficacy and compatibility mechanism of bear bile powder in Shexiang Tongxin dropping pills for acute myocardial infarction treatment
Published 2025-01-01“…Our findings suggested that combination treatment with CF and BBP synergistically attenuates AMI by altering gene expression, gut microbiota, and intestinal metabolite profiles. …”
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14559
Total HLA Class I Antigen Loss with the Downregulation of Antigen-Processing Machinery Components in Two Newly Established Sarcomatoid Hepatocellular Carcinoma Cell Lines
Published 2018-01-01“…Unlike sHCC74 and SAR-HCV, both sHCC29 and sHCC63 had no detectable surface HLA class I antigen expression, alongside undetected intracellular β2-microglobulin (β2m) and marked HLA class I heavy chain and selective antigen-processing machinery (APM) component downregulation. …”
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14560
VDR Polymorphisms in Autoimmune Connective Tissue Diseases: Focus on Italian Population
Published 2021-01-01“…Genetic polymorphisms in the VDR gene could modulate the expression or function of the receptor and, consequently, alter the effects of vitamin D. …”
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