Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation by Aleksandra Jankovic, Aleksandra Korac, Biljana Buzadzic, Vesna Otasevic, Ana Stancic, Milica Vucetic, Milica Markelic, Ksenija Velickovic, Igor Golic, Bato Korac

“…The expression profiles of adiponectin, resistin, 5′-AMP-activated protein kinase α (AMPKα), hypoxia-inducible factor-1α (HIF-1α), and key enzymes of glucose and fatty acid metabolism and oxidative phosphorylation in rat retroperitoneal white adipose tissue (RpWAT) during 45-day cold acclimation were examined. …”
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Animal Models for Human-Pathogenic Coronavirus and Animal Coronavirus Research by Fenglian Xiao, Jincheng Hu, Minsheng Xu, Di Wang, Xiaoyan Shen, Hua Zhang, Jie Miao, Haodong Cai, Jihui Wang, Yaqing Liu, Shan Xiao, Longchao Zhu

“…These approaches include using viral delivery methods to induce the expression of viral receptors in mouse tissues and employing gene-editing techniques to create genetically modified mice. …”
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Curcumin Improves Epithelial Barrier Integrity of Caco-2 Monolayers by Inhibiting Endoplasmic Reticulum Stress and Subsequent Apoptosis by Xinxin Zhou, Mengting Ren, Jinpu Yang, Hanghai Pan, Mosang Yu, Feng Ji

“…Curcumin enhanced intestinal epithelial barrier integrity in the in vitro coculture model by upregulating TJ protein expressions and reducing intestinal epithelial cell apoptosis. …”
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Selected issues on theory and methodology of the underground press by Wanda Krystyna Roman

“…It came into existence under specific socio-political conditions and had to fulfill specific aims. The freedom of expression it offered was a counterbalance to the official newspapers. …”
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أنماط الافادة من شبکات التواصل الاجتماعیة و المهنیة لدى عینة من أعضاء هیئة التدریس بالجامعات المصریة... by د. اسماء محمد السید

“…The most positive forms of participation in the study community for the use ofsocial and professional networks varied between the access to news andinformation, learning new things through social networks, free expression ofopinion, enable overcoming the barrier of shyness between students andfaculty, and holding fruitful meetings and meetings With colleagues remotely,in addition to social networks as a means of communication and informationexchange, it is one of the most important educational tools to improve theeducational process.3. …”
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Delta-opioid receptor signaling alleviates neuropathology and cognitive impairment in the mouse model of Alzheimer’s disease by regulating microglia homeostasis and inhibiting HMGB... by Yuan Xu, Naiyuan Shao, Feng Zhi, Ronghua Chen, Yilin Yang, Jiahui Li, Ying Xia, Ya Peng

“…DOR and MOR also differentially modulated microglia in APP/PS1 mice and in vitro AD cell model with a DOR-mediated inhibition on the excessive activation of microglia and the release of pro-inflammatory cytokines in AD pathologies. Gene expression profiling further revealed that the alternations in DOR/MOR are closely associated with microglial homeostatic signatures and high mobility group protein B1 (HMGB1) in AD. …”
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Combination chemotherapy with sintilimab for treatment of a male patient with primary pulmonary choriocarcinoma: a case report and literature review by Xiaojing Liang, Guoqing Xu, Jisong Zhang, Li Xu, Liangliang Dong, Xiaoyue Wang, Weidong Han, Enguo Chen

“…Programmed death-ligand 1 (PD-L1) expression was positive (70%) in the 22C3 assay. He received a combination of cisplatin, etoposide, paclitaxel, and sintilimab. …”
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Effects of Hsa-miR-4741/LILRB2 on Senescence of Nucleus Pulposus Cells and Their Prognostic Values in Lumbar Disc Herniation by Zhendong He, Nan Zheng, Xiu-Quan Guo, Gang-Gang Wang, Mingjian Lin

“…Hsa-miR-4741 mimics attenuated the luciferase activity of NPC transfected with wt-LILRB2 vector and significantly down-regulated LILRB2 expression. In addition, the antioxidant NAC reversed the promotion of hsa-miR-4741 on NPC senescence.Conclusion The combination of hsa-miR-4741 and LILRB2 was a good predictor of LDH prognosis. …”
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The Histone Demethylase KDM3B Promotes Osteo-/Odontogenic Differentiation, Cell Proliferation, and Migration Potential of Stem Cells from the Apical Papilla by Chen Zhang, Xiao Han, Yuncun Liang, Huina Liu, Zhipeng Fan, Jianpeng Zhang

“…By an alkaline phosphatase (ALP) activity assay, Alizarin red staining, real-time RT-PCR, and western blot analysis, we found that KDM3B enhanced the ALP activity and mineralization of SCAPs and promoted the expression of runt-related transcription factor 2 (RUNX2), osterix (OSX), dentin sialophosphoprotein (DSPP), and osteocalcin (OCN). …”
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Flavocoxid, a Nutraceutical Approach to Blunt Inflammatory Conditions by Alessandra Bitto, Francesco Squadrito, Natasha Irrera, Gabriele Pizzino, Giovanni Pallio, Anna Mecchio, Federica Galfo, Domenica Altavilla

“…Flavocoxid downregulates gene or protein expression of several inflammatory markers and exerts also strong antioxidant activity in several experimental models. …”
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Identification of a New Prognostic Risk Signature of Clear Cell Renal Cell Carcinoma Based on N6-Methyladenosine RNA Methylation Regulators by Yan Zhang, Yao Yao, Xiaochen Qi, Jianyi Li, Meihong Liu, Xiangyu Che, Yingkun Xu, Guangzhen Wu

“…First, we compared the expression of 18 m6A RNA methylation regulators in ccRCC patients and normal tissues. …”
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Serum microRNAs as Diagnostic Markers in Polycystic Ovary Syndrome: A Narrative Review by K Lavanya, N Palaniappan, VM Vinodhini, Santhi Silambanan

“…Physiological development, including physical growth and embryonic development of the ovaries, alter the levels of microRNA expression. It has been discovered that the altered pattern of microRNAs under pathological circumstances is specific to certain disorders. …”
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miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway by Zhongsheng Zhu, Jinyu Li, Rui Tong, Xiaorong Zhang, Bo Yu

“…Conclusions. miR-149 prevents ox-LDL-induced endothelial cell injury by enhancing autophagy via increasing Akt and mTOR expressions.…”
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Effect of scaling on levels of interleukin 1-beta and clinical periodontal parameters among e-cigarette users and non-smokers: A prospective study by Alaa B. Alkhalifah, Nehad T. Alfuraih, Bobby Joseph, Jagan K. Baskaradoss

“…Introduction This cohort study aimed to compare the effect of ultrasonic scaling on the expression of IL-1β in the gingival crevicular fluid (GCF) among ENDS users and non-smokers (NS) with gingivitis. …”
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Evaluation of mucosal adjuvants to chitosan-nanoparticle-based oral subunit vaccine for controlling salmonellosis in broilers by Raksha Suresh, Shekoni Olaitan Comfort, Sara Dolatyabi, Jennifer Schrock, Mithilesh Singh, Gourapura J. Renukaradhya

“…Immunologically, we observed enhanced systemic and mucosal antibody and cellular (B cells and T-helper cells) immune responses as well as upregulation of expression of immune cytokine genes IFN-γ, TGF-β, and IL-17 in the cecal tonsils of adjuvanted mChitosan-NP Salmonella-subunit-vaccinated birds. …”
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The Roles of Autophagy in Acute Lung Injury Induced by Myocardial Ischemia Reperfusion in Diabetic Rats by Liying Zhan, Yuan Zhang, Wating Su, Qiongxia Zhang, Rong Chen, Bo Zhao, Wei Li, Rui Xue, Zhongyuan Xia, Shaoqing Lei

“…Diabetic rats subjected to myocardial IR showed more serious ALI with higher lung injury score and WET/DRY ratio and lower PaO2 as compared with control rats, accompanied with impaired autophagy indicated by reduced LC-3II/LC-3I ratio and Beclin-1 expression, decreased superoxide dismutase (SOD) activity, and increased 15-F2t-Isoprostane formation in lung tissues, as well as increased levels of leukocyte count and proinflammatory cytokines in BAL fluid. …”
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Cancer stem cell populations are resistant to 5-aminolevulinic acid-photodynamic therapy (5-ALA-PDT) by Chantel P. J. Rice, Vipin Shankar Chelakkot, Noah T. Conohan, Kensuke Hirasawa

“…Previously, we reported that oncogenic activation of Ras/MEK promotes PPIX efflux and reduces cellular sensitivity to 5-ALA-PDT through increased expression of ABCB1 transporter. As cancer stem cells (CSCs) are known to drive resistance to other cancer treatments and have high efflux of chemotherapeutic agents via ABC-family transporters, we hypothesize that CSCs underlie 5-ALA-PDT resistance. …”
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Towards a Noninvasive Intracranial Tumor Irradiation Using 3D Optical Imaging and Multimodal Data Registration by R. Posada, Ch. Daul, D. Wolf, P. Aletti

“…Tests performed with human data proved that the registration algorithm is accurate (0.1 mm mean distance between homologous points) and robust even for facial expression changes.…”
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Unveiling the mechanism of micro-and-nano plastic phytotoxicity on terrestrial plants: A comprehensive review of omics approaches by Asad Jamil, Ambreen Ahmad, Muhammad Moeen-ud-din, Yihao Zhang, Yuxuan Zhao, Xiaochen Chen, Xiaoyu Cui, Yindong Tong, Xianhua Liu

“…This literature review synthesizes current findings regarding MNPs-induced phytotoxicity, emphasizing alterations in gene expression, protein synthesis, metabolic pathways, and physiological disruptions as revealed through omics analyses. …”
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FPR1 affects acute rejection in kidney transplantation by regulating iron metabolism in neutrophils by Peiyuan Li, Wenbin Ji, Baotong Zhang, Haowen Jia, Jinmiao Wang, Zhaonan Sun, Yifan Wang, Weiwei Wang, Feng Qi

“…At the cellular level, blocking FPR1 inhibited the activation of the ERK1/2 pathway, decreased ferrous ion content, affected the expression of iron metabolism-related proteins, and suppressed the formation of NETs. …”
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