Forage harvesting using branch pruning compromises sustainable use and conservation of Pterocarpus erinaceus Poir., an endangered species by Bossila Séraphin Hien, Loyapin Bondé, Mohamed Mahamoud Charahabil, Sié Sylvestre Da, Joseph Issaka Boussim, Oumarou Ouédraogo

“…Branch size distribution and branch pruning ratio (PR) expressing human pressure on sampled trees were appreciated. …”
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Exosome-based targeted delivery of NF-κB ameliorates age-related neuroinflammation in the aged mouse brain by Chae-Jeong Lee, Seung Hyun Jang, Jiwoo Lim, Hyunju Park, So-Hee Ahn, Seon Young Park, Hyangmi Seo, Soo-Jin Song, Jung-A Shin, Chulhee Choi, Heon Yung Gee, Youn-Hee Choi

“…Single-cell RNA sequencing revealed that these anti-inflammatory exosomes targeted macrophages and microglia, reducing the expression of inflammation-related genes. Treatment with Exo-srIκB also suppressed the interactions between macrophages/microglia and T and B cells in the aged brain. …”
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Influence of multimodal low-opioid anesthesia on the dynamics of аnnexin V in blood plasma during cardiac surgery by S.R. Maruniak, O.A. Loskutov, O.M. Druzhyna, I.R. Malish, N.V. Korotchuk

“…The aim – to analyze the effect of anesthesia on the dynamics of аnnexin V during coronary artery bypass grafting with сardiopulmonary bypass (CPB), and the dependence of direct clinical results on the expression of аnnexin V. Materials and methods. The study included 30 patients with coronary heart disease who underwent coronary artery bypass grafting with application of 2–3 aortocoronary anastomoses with CPB. …”
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Exosomes of Antler Mesenchymal Stem Cells Improve Postoperative Cognitive Dysfunction in Cardiopulmonary Bypass Rats through Inhibiting the TLR2/TLR4 Signaling Pathway by Chun Yang, Shengnan Sun, Qi Zhang, Jia Guo, Tengfei Wu, Ying Liu, Min Yang, Yan Zhang, Yinghua Peng

“…Furthermore, AMSC-derived exosomes were found to reduce hippocampal neuronal apoptosis and the expression of TLR2, TLR4, MyD88, and NF-κB in CPB rats. …”
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“Nobody Seemed to Notice My Work”: The Lived Experiences of Home Care Workers Assisting People With Chronic Diseases: A Phenomenological Study by Valentina Cacciapuoti, Silvio Simeone, Michele Virgolesi, Medeline R. Sterling, Elisa Dallago, Ercole Vellone, Rosaria Alvaro, Gianluca Pucciarelli

“…The subjects were enrolled in several cities of Central Italy and interviewed with open questions to allow them full freedom of expression and asked to describe their lived experience of HCWs who helped people with chronic diseases. …”
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Selenium–Chondroitin Sulfate Nanoparticles Inhibit Angiogenesis by Regulating the VEGFR2-Mediated PI3K/Akt Pathway by Xia Zheng, Xiaofei Liu, Zhuo Wang, Rui Li, Qiaoli Zhao, Bingbing Song, Kit-Leong Cheong, Jianping Chen, Saiyi Zhong

“…Further mechanism analysis showed that SeCS had a strong inhibitory effect on VEGFR2 expression and its downstream PI3K/Akt signaling pathway, which contributed to its anti-angiogenic effects. …”
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Active Ingredients and Potential Mechanism of Additive Sishen Decoction in Treating Rheumatoid Arthritis with Network Pharmacology and Molecular Dynamics Simulation and Experimenta... by Ren J, Liu Z, Qi X, Meng X, Guo L, Yu Y, Dong T, Li Q

“…In vitro experiments indicated that kaempferol, luteolin, and quercetin decreased Glut1 and LDHA expression by diminishing PI3K-AKT signaling to inhibit glycolysis. …”
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Systematic Study of the Immune Components after Ischemic Stroke Using CyTOF Techniques by Yaning Li, Yan Wang, Yang Yao, Brian B. Griffiths, Liangshu Feng, Tao Tao, Feng Wang, Baohui Xu, Creed M. Stary, Heng Zhao

“…Our data showed (1) dynamic changes in the immune cell numbers in the ischemic brain and peripheral organs. (2) The expression levels of cell surface markers indicate the inflammation response status after stroke. …”
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Plasma brain-related biomarkers and potential therapeutic targets in pediatric ECMO by Sue J. Hong, Bradley J. De Souza, Kristen K. Penberthy, Lisa Hwang, David E. Procaccini, John N. Kheir, Melania M. Bembea

“…Higher concentrations of pro-inflammatory cytokines (IL-1β, IL-6, IFN-γ, TNF-α) are associated with abnormal neuroimaging, and proteomic expression panels reveal different coagulation and inflammatory responses. …”
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Avirulence depletion assay: Combining R gene-mediated selection with bulk sequencing for rapid avirulence gene identification in wheat powdery mildew. by Lukas Kunz, Jigisha Jigisha, Fabrizio Menardo, Alexandros G Sotiropoulos, Helen Zbinden, Shenghao Zou, Dingzhong Tang, Ralph Hückelhoven, Beat Keller, Marion C Müller

“…We show that AvrPm60 is encoded by three tandemly arrayed, nearly identical effector genes that trigger an immune response upon co-expression with Pm60 and its alleles Pm60a and Pm60b. …”
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Th17: A New Participant in Gut Dysfunction in Mice Infected with Trichinella spiralis by Yu Fu, Wenfeng Wang, Jingjing Tong, Qi Pan, Yanqing Long, Wei Qian, Xiaohua Hou

“…The proportion of Th17 cells and the expression of IL-17 were upregulated in jejunum at 2 weeks PI and normalized at 8 weeks PI. …”
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Deep Learning and Radiomics in Triple-Negative Breast Cancer: Predicting Long-Term Prognosis and Clinical Outcomes by Cheng C, Wang Y, Zhao J, Wu D, Li H, Zhao H

“…Chen Cheng,1,* Yan Wang,2,3,* Jine Zhao,4,* Di Wu,1 Honge Li,5 Hongyan Zhao1 1Department of Ultrasound, Lianyungang Traditional Chinese Medicine Hospital, Lianyungang, 222004, People’s Republic of China; 2Department of Ultrasound, Lianyungang Municipal Oriental Hospital, Lianyungang, 222046, People’s Republic of China; 3Department of Ultrasound, Xuzhou Medical University Affiliated Hospital, Lianyungang, Jiangsu, 222061, People’s Republic of China; 4Department of Ultrasound, Donghai County People’s Hospital, Lianyungang, Jiangsu, 222300, People’s Republic of China; 5Department of Ultrasound, the First People’s Hospital of Lianyungang, Lianyungang, Jiangsu, 222061, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hongyan Zhao, Department of Ultrasound, Lianyungang Traditional Chinese Medicine Hospital, No. 160, Chaoyang Middle Road, Haizhou District, Lianyungang, 222004, People’s Republic of China, Tel +86 0518-85574003, Email zhaohongyanzhy01@126.comAbstract: Triple-negative breast cancer (TNBC) is a unique breast cancer subtype characterized by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression in tumor cells. TNBC represents about 15% to 20% of all breast cancers and is aggressive and highly malignant. …”
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PD-L1 Blockade Attenuated Sepsis-Induced Liver Injury in a Mouse Cecal Ligation and Puncture Model by Weimin Zhu, Rui Bao, Xiaohua Fan, Tianzhu Tao, Jiali Zhu, Jiafeng Wang, Jinbao Li, Lulong Bo, Xiaoming Deng

“…Our results indicated that there was a significant increase of PD-L1 expression in liver after CLP challenge compared to sham-operated controls, in terms of levels of mRNA transcription and immunohistochemistry. …”
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Conflicts in the tourist city from the perspective of local social movements by Yolanda Romero-Padilla, Alfonso Cerezo-Medina, Enrique Navarro-Jurado, José María Romero-Martínez, Antonio Guevara-Plaza

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Quercetin improves diabetic kidney disease by inhibiting ferroptosis and regulating the Nrf2 in streptozotocin-induced diabetic rats by Lei Zhang, Xingzhi Wang, Liang Chang, Yiqun Ren, Manshu Sui, Yuting Fu, Lei Zhang, Lirong Hao

“…However, quercetin counteracted this by inhibiting ferroptosis and activating NFE2-related factor 2 (Nrf2) expression in both DKD rats and HG-treated HK-2 cells, indicating its renal protective role. …”
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Comparative analyses of the hemostatic efficacy and surgical device performance of powdered oxidized regenerated cellulose and starch-based powder formulations by Marianne Stark, Allen Y. Wang, Brittny Corrigan, Henok G. Woldu, Samar Azizighannad, Gustavo Cipolla, Richard Kocharian, Hector De Leon

“…Device performance (powder expression) was examined in vitro at 3 device positions/angles: 90° (vertical, downward), 45° (slanted, downward), and 180° (horizontal). …”
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Systemic Proteomic Analysis Reveals Distinct Exosomal Protein Profiles in Rheumatoid Arthritis by Qiu Qin, Ronghua Song, Peng Du, Chaoqun Gao, Qiuming Yao, Jin-an Zhang

“…Noteworthy, the LBP/CD14 complex can promote the expression of IL-8 and TNF-α, eventually leading to the development of RA. …”
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Mass resection as a candidate treatment for uterine PEComas of uncertain malignant potential: a case report and literature review by Haijuan Shi, Yan Yin, Shoujun Liang, Chuanzhong Liu, Yibao Huang, Bingfeng Lu, Liying Zhang

“…Patients with group A tumours (abundant HMB45 expression) had a longer disease-free survival than those with group B tumours.ConclusionsSurgery alone may be appropriate for uterine PEComas of uncertain malignant potential. …”
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Effects of Pristane Alone or Combined with Chloroquine on Macrophage Activation, Oxidative Stress, and Th1/Th2 Skewness by Qiufang Ouyang, Ziyang Huang, Zhenhua Wang, Xiaoqing Chen, Jingqin Ni, Ling Lin

“…Hematological and biochemical parameters, macrophage phagocytic function, the oxidant/antioxidant index, cytokine for IFN-γ, TNF-α, IL-4, and IL-6, and the isotypes of IgG2a and IgG1 were determined. And the expression of T-bet/GATA-3 and IL-12/IL-10 mRNA in spleen were analyzed by real-time PCR. …”
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Deciphering the mechanisms of long non-coding RNAs in ferroptosis: insights into its clinical significance in cancer progression and immunology by Shengming Ou, Xiaoya Nie, Xiangyu Qiu, Xin Jin, Geyan Wu, Rongxin Zhang, Jinrong Zhu

“…Long non-coding RNAs (LncRNAs) are a group of functional RNA molecules that are not translated into proteins, which can regulate gene expression in various manners. An increasing number of studies have shown that lncRNAs can interfere with the progression of ferroptosis by modulating ferroptosis-related genes directly or indirectly. …”
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