Role of transforming growth factor-β1 in regulating adipocyte progenitors by Nguyen Quynh Phuong, Muhammad Bilal, Allah Nawaz, Le Duc Anh, Memoona, Muhammad Rahil Aslam, Sana Khalid, Tomonobu Kado, Yoshiyuki Watanabe, Ayumi Nishimura, Yoshiko Igarashi, Keisuke Okabe, Kenichi Hirabayashi, Seiji Yamamoto, Takashi Nakagawa, Hisashi Mori, Isao Usui, Shiho Fujisaka, Ryuji Hayashi, Kazuyuki Tobe

“…Among cytokines, the role of transforming growth factor-β1 (Tgf-β1), a cytokine abundantly expressed in CD206+ M2-like macrophage and correlated with the expansion of AT and fibrosis, in AT metabolism, remains unknown. …”
Get full text

Penerapan Machine Learning untuk Mengendalikan Parameter Budidaya Tanaman Hidroponik Berbasis Edge dan Cloud Computing by Helmy Helmy, Arif Nursyahid, Thomas Agung Setyawan

“…Besides pH, the concentration of the nutrient solution, expressed in Total Dissolved Solids (TDS) in ppm, also needs to be controlled as it supplies the nutrients required by plants. …”
Get full text

Enhancing ethical self-efficacy among dementia caregiver staff: A mixed-methods feasibility study of the care programme by Sigurd Lauridsen, Sofie Smedegaard Skov, Lucca-Mathilde Thorup, Marie-Eva Berg, Anna Paldam Folker, Peter Simonsen, Frederik Schou-Juul

“…To a high/some degree, 97 % expressed satisfaction, 95 % found the programme relevant to their work, 90 % believed it would improve dementia care, and 82 % felt better equipped to handle ethical dilemmas. …”
Get full text

Evaluation of Biologics ACE2/Ang(1–7) Encapsulated in Plant Cells for FDA Approval: Safety and Toxicology Studies by Henry Daniell, Geetanjali Wakade, Smruti K. Nair, Rahul Singh, Steven A. Emanuel, Barry Brock, Kenneth B. Margulies

“…Angiotensin Converting Enzyme 2 (ACE2) gum is the first engineered human blood protein expressed in plant cells approved by the FDA without the need for purification and is a cold-chain and noninvasive drug delivery. …”
Get full text

Pharmacological Effects of Antioxidant Mycosporine-Glycine in Alleviating Ultraviolet B-Induced Skin Photodamage: Insights from Metabolomic and Transcriptomic Analyses by Kai Wang, Ling Qin, Huan Lin, Mengke Yao, Junhan Cao, Qing Zhang, Changfeng Qu, Yingying He, Jinlai Miao, Ming Liu

“…Skin metabolomic profiling identified 34 differentially abundant metabolites, and transcriptomic analysis revealed 752 differentially expressed genes. The combined metabolomic and transcriptomic data indicate that M-Gly’s protective effects may involve the regulation of ion transport, cellular repair, metabolic stability, collagen preservation, and the Nrf2/HO-1 pathway. …”
Get full text

Clinico-Epidemiological Profile of Children Orphaned due to AIDS Residing in Care Giving Institutions in Coastal South India by Rekha Thapar, Meher Singha, Nithin Kumar, Prasanna Mithra, Bhaskaran Unnikrishnan, Ramesh Holla, Vaman Kulkarni, B. B. Darshan, Avinash Kumar

“…The collected data were analyzed using SPSS (Statistical Package for Social Sciences) version 11.5 and the results expressed in mean (standard deviation) and proportions. …”
Get full text

The AFFIRM Framework for gender-affirming care: qualitative findings from the Transgender and Gender Diverse Health Equity Study by Meg Quint, Schuyler Bailar, Alexis Miranda, Shalender Bhasin, Devin O’Brien-Coon, Sari L. Reisner

“…Themes about gender-affirming care coalesced into the acronym AFFIRM: (1) Affirms in individual interactions: Participants called for affirmation of TGD identity, lived expertise, and competent TGD providers and staff. (2) Flexible and accessible: Participants expressed the need for gender-affirming care to be available beyond urban population-specific clinics, in a timely fashion without long wait lists, and in a community-centered manner such as offering non-traditional times and settings. (3) Fights systemic oppression: Participants emphasized the need for providers and health systems to eliminate gatekeeping practices for gender-affirming care and create care models that resist intersecting oppressive systems such as racism and cisgenderism. (4) Interacts with community: Patients desired intentional interaction with TGD community to holistically address health and unmet gender affirmation needs. (5) Retains patients in care: Patients shared the need to collaboratively identify and problem-solve obstacles to gender-affirming care with providers and healthcare systems to optimize TGD-specific retention strategies. (6) Multidisciplinary: Patients called for interdisciplinary teams with co-located services such as primary care and mental healthcare with letter-writing for surgical care, and incorporation of peer navigators to meet the broader social, health, and well-being needs of TGD people. …”
Get full text

Instituto de Investigaciones en Procesos Tecnológicos Avanzados, Universidad Nacional del Chaco Austral. Presidencia Roque Sáenz Peña, Chaco, Argentina by Sebastiana Failla, Michela Contò, Antonio Borghese, Vittoria Lucia Barile

“…After the extraction and methylation of fat, fatty acids, using the GC/FID instrument, were quantified, and expressed as mg/g of fat. Data were analyzed by ANOVA, considering only diet as a factor. …”
Get full text

miRNA-375 a Sensor of Glucotoxicity Is Altered in the Serum of Children with Newly Diagnosed Type 1 Diabetes by Lucien Marchand, Audrey Jalabert, Emmanuelle Meugnier, Kathleen Van den Hende, Nicole Fabien, Marc Nicolino, Anne-Marie Madec, Charles Thivolet, Sophie Rome

“…As miR-375 is highly expressed in the endocrine pancreas, we postulated that its circulating level might reflect beta cell alterations and might be altered in the blood of T1D patients recently diagnosed. …”
Get full text

Rhein Mitigates Lung Injury in Severe Acute Pancreatitis Through the Inhibition of MARK4-Mediated Microtubule Destabilization by Sun Z, Liu J, Ge P, Cao Y, Liu J, Wen H, Luo X, Pei B, Jin Z, Li H, Xun L, Luo Y, Yang Q, Chen H

“…Compared with LPS stimulation, a total of 2081 differentially expressed genes were identified after MARK4 knockdown. …”
Get full text

In Vitro Determination of Antimicrobial, Antioxidant and Antiviral Properties of Greek Plant Extracts by Aliki Tsakni, Eirini Kyriakopoulou, Sophia Letsiou, Panagiotis Halvatsiotis, Haralambos Rigopoulos, Niki Vassilaki, Dimitra Houhoula

“…Similarly, the results of the antiviral potential of extracts were expressed as EC₅₀ values, and <i>Eucalyptus globulus</i> L. was characterized as the most effective sample against dengue virus infection, with EC₅₀ values estimated at 2.37% <i>v</i>/<i>v</i> ± 0.6 (HuhD-2 cells infected with DENV-2) and 0.36% <i>v</i>/<i>v</i> ± 0.004 (Huh7.5 cells infected with DVR2A). …”
Get full text

Hypoxia Induced Lnc191 Upregulation Dictates the Progression of Esophageal Squamous Cell Carcinoma by Activating GRP78/ERK Pathway by Sisi Wei, Xinyi Fan, Xiaoya Li, Wei Zhou, Zhihua Zhang, Suli Dai, Huilai Lv, Yueping Liu, Baoen Shan, Lianmei Zhao, Qimin Zhan, Yongmei Song

“…In the present study, a novel hypoxia‐induced long noncoding RNA (lncRNA) is identified first, lnc191, which is highly expressed in clinical ESCC tissues and is positively correlated with poor prognosis of ESCC patients. …”
Get full text

Effects of Ivabradine on Residual Myocardial Ischemia after PCI Evaluated by Stress Echocardiography by Simone Calcagno, Fabio Infusino, Olga Dettori, Temistocle Taccheri, Pasqualina Bruno, Viviana Maestrini, Gennaro Sardella, Massimo Mancone, Francesco Fedele

“…The exercise time was longer in IG 9′49″ ± 48″ vs 8′09″ ± 59″ in CG (p=0.0001), reaching a greater workload (IG 139.3 ± 13.4 vs CG 118.7 ± 19.6 Watts; p=0.003). MVO2 expressed with DP and TP was significantly higher in IG (DP: IG 24194 ± 2697 vs CG 20358 ± 4671.8, p=0.01; TP: IG 17239 ± 4710 vs CG 12206 ± 4413, p=0.007). …”
Get full text

Indicators of free radical oxidation in neutrophils of patients with primary and recurrent soft tissue sarcomas by I. A. Goroshinskaya, I. V. Kaplieva, E. M. Frantsiyants, L. N. Vashchenko, T. O. Lapteva, T. V. Ausheva, L. A. Nemashkalova, P. S. Kachesova, Yu. Yu. Kozel

“…Women of the older age group were characterized by activation of SOD and GPx, expressed in the relapsed process to a significantly greater extent than in men, and an increase in RG was observed in women. …”
Get full text

Causal associations of ambient particulate matter 10 and Alzheimer’s disease: result from a two-sample multivariable Mendelian randomization study by Zehan Huang, Guodong He, Shuo Sun, Yingqing Feng, Yuqing Huang

“…The MR estimates of causality association were expressed as odds ratios (OR) and corresponding 95% confidence intervals (CI). …”
Get full text

Impact of a Supervised Twelve-Week Combined Physical Training Program in Heart Failure Patients: A Randomized Trial by Tainá Fabri, Aparecida Maria Catai, Fábio H. O. Ribeiro, Jonas A. Araújo Junior, Juliana Milan-Mattos, Danielle A. A. Rossi, Regina C. Coneglian, Ricardo C. Borra, Silmeia Garcia Zanati Bazan, João Carlos Hueb, Beatriz Bojikian Matsubara, Meliza Goi Roscani

“…Categorical variables were expressed as proportions and compared with the chi-square test. …”
Get full text

Integration of ATAC-seq and RNA-seq reveals signal regulation during post-molt and inter-molt stages in muscle of Eriocheir sinensis by Bin Wang, Bin Wang, Jingjing Li, Mingzhi Zhang, Mingzhi Zhang, Anqi Li, Zhentao Song, Zhentao Song, Zhen He, Zhen He, Ruiqi Zhang, Ruiqi Zhang, Tong Hao, Tong Hao, Jinsheng Sun, Jinsheng Sun

“…In all the enriched signaling pathways, GPCR signaling pathway includes the most differentially expressed genes (8 genes), which underlines its importance in the signal transduction from the post-molt stage to the inter-molt stage. …”
Get full text

Legal regime of property registration: civil-legal aspect by Serdyuk R.

“…Originality. The position is expressed regarding the evidentiary value of the state registration of rights arising from the moment of acceptance of the inheritance, rather than the legal value (legal fact). …”
Get full text

Efficacy of personalized feedback in encouraging sustainable washing behavior: evidence from a pilot study in Germany by Laura Höpfl, Laura Höpfl, Laura Höpfl, Ivan Đula, Ivan Đula, Ivan Đula, Francisco Kiss, Rebecca Walter, Maria Wirzberger, Maria Wirzberger, Maria Wirzberger

“…Furthermore, participants qualitatively reported habitual changes, feeling more knowledgeable about the monetary impacts of specific washing programs and temperatures, and wished for a more accessible preset time function. Most participants expressed willingness to switch to a dynamic energy price if it translated to significant cost savings.DiscussionOur findings may support the notion that individualized behavior change strategies are promising. …”
Get full text

Nano-delivery platform with strong protection and efficient delivery: preparation of self-assembled RNA pesticide with dual RNAi targets against Apolygus lucorum by Heng Qiao, Qinhong Jiang, Jing Zhao, Liubin Xiao, Keyan Zhu-Salzman, Dejin Xu, Guangchun Xu, Jie Shen, Aiguo Gu, Dejun Hao, Shuo Yan, Yongan Tan

“…Then, dsECR-A and dsTre-1 fragments were individually screened, and the dsECR-A and dsTre-1 fragments with good control effects were co-expressed in pET28-BL21 (DE3) RNase III − system to prepare the dsECR-A + Tre-1/SPc complex. …”
Get full text