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14041
Artificial intelligence in higher education: problems, opportunities, risks
Published 2024-12-01“…Analytical and theoretical research methods (literature analysis, data synthesis, generalization, induction, deduction, establishment of cause-and-effect relationships) were applied to assess the current state of the educational sphere regarding the widespread introduction of AI capabilities, and an express survey was conducted in the number of 105 people: students of additional education programs “Teacher” and “Teacher of a higher educational institution” on the topic of psychological adaptation to the active use of AI technologies in the framework of pedagogical practice. …”
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14042
Resistance of <i>Wolbachia</i> to Trimethoprim: Insights into Genes Encoding Dihydrofolate Reductase, Thymidylate Synthase and Serine Hydroxymethyltransferase in the Rickettsiales
Published 2024-12-01“…In contrast, <i>Wolbachia</i> and other Rickettsiales express the unconventional FAD-TS enzyme encoded by <i>thyX</i>, even when <i>folA</i> is present. …”
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14043
The role of KNDy neurons in human reproductive health
Published 2024-08-01“…ARC Kiss1 neurons co-express neurokinin B (NKB) and dynorphin and are thus termed KNDy neurons. …”
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14044
Audiological alterations in resistance to thyroid hormone syndrome: emphasizing lifelong assessment
Published 2025-02-01“…The cochlea and inner ear express thyroid hormone receptor beta (THRB) in developmental stages. …”
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14045
Androgen metabolism and inhibition of interleukin-1 synthesis in primary cultured human synovial macrophages
Published 1995-01-01“…It is now reported that primary cultured human macrophages obtained from normal and rheumatoid synovia express functional androgen receptors. We have investigated the capacity of cultured macrophages to metabolize androgens and have found that these cells were capable of metabolizing testosterone to the bioactive metabolite dihydrotestosterone. …”
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14046
Multiplex-PCR technique to predict polymorphic antigens – M, N, S and s – and associations between their alleles and Mia-associated hybrid glycophorins
Published 2025-01-01“…Individuals with the GYPA*M/M and GYPB*s/s genotypes, predicted M + N − S− s + phenotypes, will thus most likely to express the Mi(a+) antigen. Nevertheless, further studies are required to validate these results and elucidate the underlying correlations.…”
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14047
CD44-Receptors-Mediated Multiprong Targeting Strategy Against Breast Cancer and Tumor-Associated Macrophages: Design, Optimization, Characterization, and Cytologic Evaluation
Published 2025-01-01“…For selective targeting through CD44-receptors that are heavily expressed on the BC cells and TAMs, the fabricated NPs (PTX-TMX-CS-NPs) were functionalized with hyaluronic acid (HA) as a targeting ligand.Results: The optimized HA-PTX-TMX-CS-NPs exhibited desired physicochemical properties (PS ~230 nm, PDI 0.30, zeta potential ~21.5 mV), smooth spherical morphology, high encapsulation efficiency (PTX ~72% and TMX ~97%), good colloidal stability, and biphasic release kinetics. …”
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14048
MUC5B modulation of early oral biofilm glucose metabolism
Published 2025-02-01“…A pathway enrichment analysis of the metabolites that were differently expressed in early A. naeslundii, S. gordonii, and dual-species biofilms grown with 20 mM glucose with or without MUC5B showed that pyruvate metabolism was significantly over-represented. …”
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14049
Lipoprotein-Associated Phospholipase A2 Mass Level Is Increased in Elderly Subjects with Type 2 Diabetes Mellitus
Published 2014-01-01“…Lipoprotein-associated phospholipase A2 (Lp-PLA2) is extensively expressed by advanced atherosclerotic lesions and may play a role in plaque instability. …”
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14050
PARylation of HMGA1 desensitizes esophageal squamous cell carcinoma to olaparib
Published 2024-12-01“…Moreover, HMGA1 was highly expressed in ESCC tissues and positively correlated with PARP1 levels as well as poor prognosis in ESCC patients. …”
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14051
Gender-based Morphometric Analysis of the Human Orbital Aperture Profile using 3D Reconstruction Computed Tomography: A Cross-sectional Retrospective Study
Published 2025-01-01“…All continuous data were tested for normality and expressed as Mean±Standard deviation (SD). The significant differences in orbital measurements between males and females were assessed using the Independent t-test. …”
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14052
Prediction of growth and feed efficiency in mink using machine learning algorithms
Published 2025-02-01“…The feed efficiency (FE) expresses as the amount of feed required per unit of BW gain. …”
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14053
Gibberellin-3 induced dormancy and suppression of flower bud formation in pitaya (Hylocereus polyrhizus)
Published 2025-01-01“…Transcriptomic analysis revealed batches of differentially expressed genes (DEGs) associated with phytohormone signal transduction, aligning with observed hormone changes. …”
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14054
Conversion of placental hemogenic endothelial cells to hematopoietic stem and progenitor cells
Published 2025-01-01“…Furthermore, comparative transcriptome analysis of aHE-iHSPCs and pHE-iHSPCs showed that aHE-iHSPCs highly expressed HSC-specific and self-renewal-related genes. …”
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14055
Effects of Long-Term Dietary Administration of Kale ( Brassica oleracea L. var. acephala DC) Leaves on the Antioxidant Status and Blood Biochemical Markers in Rats
Published 2022-08-01“…Antioxidant potential in serum was measured and expressed as Trolox equivalents antioxidant capacity (TEAC). …”
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14056
Assessment of Physicochemical Properties of Rituximab Related to Its Immunomodulatory Activity
Published 2015-01-01“…It binds specifically to the CD20 antigen expressed on pre-B and consequently on mature B-lymphocytes of both normal and malignant cells, inhibiting their proliferation through apoptosis, CDC, and ADCC mechanisms. …”
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14057
Gas-phase fractionation DDA promotes in-depth DIA phosphoproteome analysis
Published 2025-01-01“…We used GPF-DDA hybrid DIA phosphoproteomics to characterize lung tissue upon direct (smoke induced) and indirect (sepsis induced) acute lung injury (ALI) in mice. The differentially expressed phosphosites (DEPsites) in direct ALI were found in proteins related to mRNA processing and RNA. …”
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14058
Cellular heterogeneity and cytokine signatures in acute myeloid leukemia: A novel prognostic model
Published 2025-02-01“…Through meticulous analysis, we identified 156 differentially expressed cytokine-related genes that underscore the nuanced interplay between AML cells and their microenvironment. …”
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14059
Choroidal Thickness in Eyes with Band Atrophy of the Optic Nerve from Chiasmal Compression
Published 2022-01-01“…The thickness of the peripapillary retinal nerve fiber layer (pRNFL), the peripapillary choroid (pChoroid), the macular RNFL (mRNFL), the macular ganglion cell layer (mGCL), and the macular choroid (mChoroid) was expressed globally and by sector (peripapillary quadrants and macular hemifield and quadrants). …”
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14060
Biochemical characterization of the Escherichia coli surfaceome: a focus on type I fimbriae and flagella
Published 2025-02-01“…The Escherichia coli surfaceome consists mainly of the large surface organelles expressed by the organism to navigate and interact with the surrounding environment. …”
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