Intermittent Administration of Parathyroid Hormone Enhances Odonto/Osteogenic Differentiation of Stem Cells from the Apical Papilla via JNK and P38 MAPK Pathways by Xiyao Pang, Ying Zhuang, Zehan Li, Shuanglin Jing, Qin Cai, Fengge Zhang, Changao Xue, Jinhua Yu

“…An ALP activity assay determined that 10-8 mol/L PTH was the optimal concentration for the induction of SCAPs with no significant influence on the proliferation of SCAPs as indicated by CCK-8, FCM, and EdU. The expression of odonto/osteogenic markers was significantly upregulated in mRNA levels and protein levels. …”
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La Nòva Cançon occitana : révolution en occitan, révolution dans la chanson occitane ? by Philippe Martel

“…On essaiera de suivre cette chanson occitane dans son parcours, jusqu’à son essoufflement final dans la seconde partie des années 1970, quand elle est relayée par d’autres formes musicales d’expression de la revendication occitane.…”
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Freezing and melting of a bath material onto a cylindrical solid additive in an agitated bath by Singh U.C., Prasad A., Kumar Arbind

“…The model provides the closed-form expressions for both the growth of the frozen layer thickness, ξ onto the additive and the heat penetration depth, η in the additive. …”
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A Novel Insight into Paraptosis-Related Classification and Signature in Lower-Grade Gliomas by Xi-Feng Qian, Jia-Hao Zhang, Yue-Xue Mai, Xin Yin, Yu-Bin Zheng, Zi-Yuan Yu, Guo-Dong Zhu, Xu-Guang Guo

“…The parallel results were reappeared and verified by using the Chinese Glioma Genome Atlas and Gene Expression Omnibus databases. Independent prognostic analysis and nomogram construction implied that risk scores could be considered the independent factor to predict OS. …”
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Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity by Dyah Ika Krisnawati, Yung-Ching Liu, Yuarn-Jang Lee, Yun-Ting Wang, Chia-Ling Chen, Po-Chun Tseng, Ting-Jing Shen, Chiou-Feng Lin

“…The interferon- (IFN-) γ expression is elicited in response to microbial infections and activates immune surveillance by antimicrobial immune elements to induce microbial killing. …”
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Inhibition of Notch Signaling Promotes the Differentiation of Epicardial Progenitor Cells into Adipocytes by Bin Liu, Dinghui Wang, Tianhua Xiong, Yajie Liu, Xiaodong Jing, Jianlin Du, Qiang She

“…EPCs had lipid droplet accumulation, and the expression of adipocyte markers FABP-4 and perilipin-1 was upregulated under adipogenic induction. …”
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Decitabine Increases the Transcription of <i>RIG-I</i> Gene to Suppress the Replication of Feline Calicivirus and Canine Influenza Virus by Shaotang Ye, Zhen Wang, Aolei Chen, Ying Chen, Gaoming Lou, Qingmei Xie, Gang Lu, Shoujun Li

“…Decitabine has been proven to modulate gene expression through its demethylating effect. Thus, we carried out further experiments and found that decitabine inhibited the FCV by enhancing the transcription of the feline <i>Retinoic acid-inducible gene I (RIG-I)</i> gene. …”
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Siponimod supports remyelination in the non-supportive environment by Johann Krüger, Newshan Behrangi, David Schliep, Leo Heinig, Elise Vankriekelsvenne, Nicole Wigger, Markus Kipp

“…At the end of week seven, loss of myelin staining intensities was still pronounced, but anti-myelin basic protein (MBP) and myelin-associated glycoprotein (MAG) expression was significantly higher in Siponimod- versus vehicle-treated mice. …”
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Advancing ex vivo functional whole-organ prostate gland model for regeneration and drug screening by Karthikeyan Subbiahanadar Chelladurai, Jackson Durairaj Selvan Christyraj, Kamarajan Rajagopalan, Johnson Retnaraj Samuel Selvan Christyraj

“…Alkaline phosphatase expression analysis confirmed that the stem cell niche is localized to the anterior region. …”
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Identification of bapA in Strains of Salmonella enterica subsp. enterica Isolated from Wild Animals Kept in Captivity in Sinaloa, Mexico by Gabriela Silva-Hidalgo, Martin López-Valenzuela, Nora Cárcamo-Aréchiga, Silvia Cota-Guajardo, Mayra López-Salazar, Edith Montiel-Vázquez

“…Each isolate amplified a product of 667 bp, which corresponds to the expected size of the bapA initiator, with no observed variation between different serovars analyzed. bapA gene was found to be highly conserved in Salmonella and can be targeted for the genus-specific detection of this organism from different sources. Since bapA expression improves bacterial proliferation outside of the host and facilitates resistance to disinfectants and desiccation, the survival of Salmonella in natural habitats may be favored. …”
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YTHDF2 mediates the protective effects of MG53 on myocardial infarction injury via recognizing the m6A modification of MG53 by Zhaojie Li, Kai Li, Jianqiang Zhao

“…Materials and methods We established hypoxia/reoxygenation (H/R) H9c2 cell and myocardial ischemia reperfusion (I/R) rat models. MG53 expression was detected using RT-qPCR, and its m6A levels were measured using Me-RIP. …”
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Nitrous oxide exerts rewarding effect via regulating D1 receptor and BDNF pathway in ventral tegmental area-nucleus accumbens dopamine circuit by Wen-Qi Li, Sheng-Nan Liu, Si-Chang Yang, Xiang Lin, Zhang-Jin Zhang

“…The repeated N2O exposure also upregulated the expression of brain-derived neurotrophic factor (BDNF) in the VTA and its multiple downstream mediators in the NAc. …”
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Evaluation of Clinical and Immunological Responses: A 2-Year Follow-Up Study in Children with Allergic Rhinitis due to House Dust Mite by Heleen Moed, Roy Gerth van Wijk, Rudi W. Hendriks, J. C. van der Wouden

“…The following variables were compared: clinical symptoms, allergen skin tests, specific IgE, T-cell proliferation, IL-5, IL-13, IFN-gamma, IL-10, TGF-beta, CD4+CD25hi cells, and Foxp3 expression. Results. Allergic symptoms had decreased after two years. …”
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Prediction of circRNA-miRNA Associations Based on Network Embedding by Wei Lan, Mingrui Zhu, Qingfeng Chen, Jianwei Chen, Jin Ye, Jin Liu, Wei Peng, Shirui Pan

“…Increasing biological experiments have shown that circRNAs play an important role in many diseases by acting as a miRNA sponge to indirectly regulate the expression of miRNA target genes. Therefore, predicting associations between circRNAs and miRNAs can promote the understanding of pathogenesis of disease. …”
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Prediction and Analysis of PDC Bit Wear in Conglomerate Layer with Machine Learning and Finite-Element Method by Li-qiang Wang, Ming-ji Shao, Wei Zhang, Zhi-peng Xiao, Shuo Yang, Ming-he Yang

“…Then, machine learning methods for equal-probability gene expression programming (EP-GEP) were used. Based on the accuracy of the training set, the effectiveness of this method in predicting the wear of PDC bits was demonstrated by verifying the dataset. …”
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Robust genome editing activity and the applications of enhanced miniature CRISPR-Cas12f1 by Soo-Ji Park, Sungjin Ju, Won Jun Jung, Tae Yeong Jeong, Da Eun Yoon, Jang Hyeon Lee, Jiyun Yang, Hojin Lee, Jungmin Choi, Hyeon Soo Kim, Kyoungmi Kim

“…Furthermore, we demonstrate that eCas12f1 efficiently induces apoptosis in cancer cells and is compatible with base editing and regulation of gene expression, verifying its high utility and applicability in gene therapy research.…”
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Discriminatory Value of Adiponectin to Leptin Ratio for COVID-19 Pneumonia by Federica Tonon, Stefano Di Bella, Fabiola Giudici, Verena Zerbato, Ludovica Segat, Raffaella Koncan, Andrea Misin, Barbara Toffoli, Pierlanfranco D’Agaro, Roberto Luzzati, Bruno Fabris, Stella Bernardi

“…Patients with COVID-19 pneumonia had higher levels of leptin, lower adiponectin/leptin (Adpn/Lep) ratio, and higher expression of IL-6. Leptin had an acceptable discriminatory accuracy for COVID-19 pneumonia in patients with BMI >30 (AUC 0.74 [0.58, 0.90]) with a cutoff of 7852 pg/mL and it was associated with maximum respiratory support. …”
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Tannic acid elicits differential gene regulation in prostate cancer apoptosis by Kandir Sinan, Karakurt Sevtap, Gökçek-Saraç Çiğdem, Karakurt Serdar

“…Cell proliferation, cytotoxicity, and effects of tannic acid on the cell death mechanism were evaluated. mRNA expression levels of 84 genes were explored in cells following tannic acid treatment. …”
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Analysis of Upper Facial Weakness in Central Facial Palsy Following Acute Ischemic Stroke by Monton Wongwandee, Kantham Hongdusit

“…Upper facial weakness was defined as asymmetry in at least one upper facial expression. Multivariable logistic regression was performed to identify factors associated with upper facial weakness. …”
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Genetic Variants of Neurotransmitter-Related Genes and miRNAs in Egyptian Autistic Patients by Ahmed M. Salem, Samira Ismail, Waheba A. Zarouk, Olwya Abdul Baky, Ahmed A. Sayed, Sawsan Abd El-Hamid, Sohair Salem

“…MAOA uVNTR was genotyped by PCR, MAOB and DRD2 polymorphisms were analyzed by PCR-based RFLP, and miR-431 and miR-21 were sequenced. Low expressing allele of MAOA uVNTR was frequently higher in female patients compared to that in controls (OR = 2.25). …”
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