Adenosine-Induced NLRP11 in B Lymphoblasts Suppresses Human CD4+ T Helper Cell Responses by Irem Ozel, Ilgin Akkaya, Ece Oylumlu, Goksu Uzel, Ceren Ciraci

“…Furthermore, cocultures of NLRP11-expressing Burkitt’s lymphoma cells and naïve human peripheral CD4+ T lymphocytes had reduced IFN-γ and IL-17A production, whereas IL-13 and IL-10 cytokines did not change. …”
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THE IMPACT OF ARTIFICIAL INTELLIGENCE IN FOREIGN LANGUAGE LEARNING USING LEARNING MANAGEMENT SYSTEMS: A SYSTEMATIC LITERATURE REVIEW by Oke Oluwafemi Ayotunde, Dashty Ismil Jamil, Nadire Cavus

“…It also gives people the opportunity for self-expression on a global standard level. Although the learning process of a foreign language can sometimes be difficult for both learners and teachers in terms of the various aspects of language learning, which includes; reading, writing, speaking, and listening skills. …”
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The Role of NF-κB/MIR155HG in Regulating the Stemness and Radioresistance in Breast Cancer Stem Cells by Yunbao Xu, Lu Yang, Guangming Li, Chuangzhou Rao

“…Methods: Effects of MIR155HG knockdown on BCSCs were gauged in MCF-7 and MDA-MB-231 cell lines. MIR155HG expression was manipulated in cells, followed by an assessment of stemness, DNA damage repair, apoptosis, cell cycle, and the Wnt signaling pathway under radiation conditions. …”
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Noncanonical effects of vasopressin in angiogenesis by I. I. Khegay

“…Platelets and endotheliocytes expressing V1a and V2 receptor types, respectively, are related to less investigated targets of the hormone. …”
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Synthesis and Evaluation of In Vitro Antibacterial and Antitumor Activities of Novel N,N-Disubstituted Schiff Bases by Heng Luo, Yu-fen Xia, Bao-fei Sun, Li-rong Huang, Xing-hui Wang, Hua-yong Lou, Xu-hui Zhu, Wei-dong Pan, Xiao-dong Zhang

“…Moreover, we observed that the antibacterial action of 1a might be associated with the regulation of the expression of key virulence genes in S. aureus. Compound 1c resulted in a strong apoptotic activity against leukemia cells, also affecting the cell cycle distribution. …”
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The Role of Quercetin and Exercise in Modulating Apoptosis and Cardiomyopathy via PI3K/AKT/FOXO3 Pathways in Diabetic Obese Rats by Mojdeh Khajehlandi, Lotfali Bolboli

“…One-way analysis of variance with LSD’s post-hoc test with a significant level ofP≤0.05 was used to analyze data.Results: Just 8 weeks of HIIT and MICT protected the protein content of PI3K, AKT, and FOXO3 and caspase-8 (Casp-8) gene expression in heart tissues (P<0.05). Quercetin and both training protocols decreased blood glucose, whileimproving inflammatory markers and the lipid profile (P<0.05).Conclusion: Reduction in blood glucose along with improvements in the inflammatory markers and the lipid profile byquercetin injection may be a promising approach for the development of new antidiabetic medications. …”
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Imaginarios de gente joven sobre política: Vereda Alto Bonito-Manizales, Colombia by Cristian David Soto Ospina, Johanna Vásquez Jaramillo, Yudi Bibiana Cardona Loaiza

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Marek's disease virus-1 unique gene LORF1 is involved in viral replication and MDV-1/Md5-induced atrophy of the bursa of Fabricius. by Chenyi Bao, Jun Chu, Qi Gao, Shasha Yang, Xiaoyu Gao, Wenwen Chen, Fuchun Yang, Fei Jiang, Chenxi Tong, Mingyi Lei, Linlin Jiao, Jitong Li, Kexin Wei, Xue Lian, Kai Li, Suresh Kumar Tikoo, Nikolaus Osterrieder, Lorne A Babiuk, Yufeng Li, Yong-Sam Jung, Yingjuan Qian

“…Subsequently, rMd5ΔLORF1, a recombinant Md5 virus deficient in pLORF1 expression, was generated by a frameshift mutation in the LORF1 gene. …”
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Development of a 3-MicroRNA Signature and Nomogram for Predicting the Survival of Patients with Uveal Melanoma Based on TCGA and GEO Databases by Jun Zuo, Hongquan Ye, Jing Tang, Jianqun Lu, Qi Wan

“…Then, miRNAs data of GSE84976 and GSE68828 were downloaded from Gene Expression Omnibus (GEO) database for outside verification. …”
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MicroRNA-451 as an Early Predictor of Chronic Kidney Disease in Diabetic Nephropathy by Mostafa Abdelsalam, A. M. Wahab, Maysaa El Sayed Zaki, Mohamad Motawea

“…This study included ninety patients with type 2 DM in addition to 30 control subjects. MicroRNA-451 expression in blood and plasma using real-time PCR was evaluated in addition to the classic diabetic nephropathy markers (serum creatinine, urinary albumin, and eGFR). …”
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A Robust Metatranscriptomic Technology for Population-Scale Studies of Diet, Gut Microbiome, and Human Health by Andrew Hatch, James Horne, Ryan Toma, Brittany L. Twibell, Kalie M. Somerville, Benjamin Pelle, Kinga P. Canfield, Matvey Genkin, Guruduth Banavar, Ally Perlina, Helen Messier, Niels Klitgord, Momchilo Vuyisich

“…Viomega includes sample collection, ambient temperature sample preservation, total RNA extraction, physical removal of ribosomal RNAs (rRNAs), preparation of directional Illumina libraries, Illumina sequencing, taxonomic classification based on a database of >110,000 microbial genomes, and quantitative microbial gene expression analysis using a database of ~100 million microbial genes. …”
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Los sistemas de información para la gerencia en salud pública by Lenin Constantino Valeri Ramírez

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Tire rubber-derived contaminants 6PPD and 6PPD-quinone reduce attachment and outgrowth of trophoblast spheroids onto endometrial epithelial cells by Jong Geol Lee, Seon Min Lee, Moonjung Hyun, Jeong Doo Heo

“…A similar result was observed in 1 μM 6PPDQ-exposed groups. Gene expression profiling of 6PPD- and 6PPDQ-exposed endometrial epithelial cells revealed that both 6PPD and 6PPDQ differentially regulated a panel of transcript markers toward overall downregulation of receptivity and invasion. …”
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Microbial signatures in head and neck squamous cell carcinoma: an in silico study by Loganathan KAVITHA, Manogaran KUZHALMOZHI, Jayaseelan VIJAYASHREE PRIYADHARSINI, Arunachalam ARUN KUMAR, Krishna Mohan Rao UMADEVI, Kannan RANGANATHAN

“…Methodology The microbe-host transcriptomic, proteomic, and epigenetic analyses of HNSCC and GI carcinomas were performed using The Cancer Microbiome Atlas (TCMA) database. The differential expression of the host’s mRNA transcripts and proteins associated with tumor microbiome were analyzed using The University of Alabama at Birmingham Cancer data analysis (UALCAN) and Clinical Proteomic Tumor Analysis Consortium (CPTAC) websites. …”
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La tension dans le processus de grammaticalisation. Une contribution à la typologie phonétique des langues by Roser Gauchola

“…La recherche a consisté à analyser la tension minimale, i.e. la distension, associée par le Système verbo-tonal à la composante grammaticale de la parole, dont on a souligné par ailleurs l’iconicité des manifestations entre plan de l’expression et plan du contenu. Partant de ces principes, nous avons constitué un corpus de différentes manifestations du processus de grammaticalisation en anglais, chinois, catalan, espagnol, français et italien comme exemple de mécanisme de distension opéré dans ces langues. …”
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Chlamydial bacteriophage: No Role in Acute Coronary Events? by David M Patrick, Karuna Karunakaran, Adrian R Levy, Kenneth Gin, Valencia Remple, Mei Chong, Heather Abbey, Laura Tarry, Caixia Shen, Robert C Brunham

“…It has been hypothesized that a bacteriophage-infected subset of C pneumoniae may be uniquely equipped to promote atherosclerosis and acute coronary syndromes through the expression of phage genes. METHODS: The authors performed a pilot case-control study of acute coronary events. …”
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An Open‐Label Phase II Trial of Pembrolizumab, an Immune Checkpoint Inhibitor Alone or in Combination With Oral Azacitidine as Second‐Line Therapy for Advanced Head and Neck Squamo... by Vinod K. Ramani, Srimonta Gayen, Radheshyam Naik

“…Epigenetics are heritable reversible changes in gene expression that occur without any changes in the nuclear DNA sequence or DNA copy number. …”
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Psychological stressors of imprisonment and coping of older incarcerated persons: a qualitative interview study by Stuart McLennan, Leila Meyer, Tenzin Wangmo, Jens Gaab, Bernice Elger, Helene Seaward

“…Participants reported five main ways that older incarcerated persons coped with the psychological stressors in prison: 1) recognising a lack of control over situation, 2) withdrawing and isolating, 3) self-improvement, 4) staying connected to the outside world, and 5) self-expression. Conclusions To improve the psychological well-being of older incarcerated persons, there is a need for: specialised training of prison staff regarding hardships that elderly persons can face in prison relationships, encouragement and enablement of social contacts with the outside world, and increasing possibilities for autonomy, new challenges, and thus stimuli within a limited setting.…”
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Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy by Constanza J. Cortes, Kefeng Qin, Eric M. Norstrom, William N. Green, Vytautas P. Bindokas, James A. Mastrianni

“…Compared with Wt-PrP, Mut-PrP expression was associated with an elevation in several markers of the autophagy-lysosomal pathway, and it extensively colocalized with the autophagosome-specific marker, LC3B. …”
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Semantic and Syntactic Dimensional Analysis of Rural Wooden Mosque Architecture in Borçka by Birgül Çakıroğlu, Reyhan Akat, Evren Osman Çakıroğlu, Taner Taşdemir

“…This research is important in terms of being a reference for the concrete expression of the concepts that we cannot see in architectural formations but we can feel that they exist.…”
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