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13701
Ensino de história, música popular brasileira e relações de gênero em sala de aula: perspectivas teóricas e metodológicas
Published 2021-08-01“…O referido curso teve como objetivo abordar as potencialidades da música popular brasileira nas aulas de História do Brasil, para a discussão e compreensão das relações de gênero, visando a capacitação de professores e acadêmicos acerca da música enquanto expressão de um povo, como documento, linguagem, como instrumento de construção de subjetividades, como ferramenta didático-pedagógica e as possibilidades de seu uso nas aulas de História. …”
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13702
Functional Outcomes After Total Knee Arthroplasty: Comparing Knee Society and Osteoarthritis Outcome Scores
Published 2025-01-01“…However, the changes were not as visible when compared to 12 months. 89% of the individuals responded satisfactorily one year following TKA, expressing their delight with the outcomes of the surgery. …”
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13703
Disease-Specific Autoantibodies Induce Trained Immunity in RA Synovial Tissues and Its Gene Signature Correlates with the Response to Clinical Therapy
Published 2020-01-01“…Moreover, the cIgG-trained gene signatures were enriched in synovial tissues from patients with ACPA- (anticitrullinated protein antibody-) positive arthralgia and undifferentiated arthritis, and early RA and established RA bore a great resemblance to the myeloid pathotype, suggesting a historical priming event in vivo. Additionally, the expression of the cIgG-trained signatures is higher in the female, older, and ACPA-positive populations, with a predictive role in the clinical response to infliximab. …”
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13704
Psychological and gender specific correlates of aggressive behaviour in military personnel
Published 2024-06-01“…It is used to analyse and understand how gender and psychological factors influence the perception and expression of aggression among men and women, particularly in the context of military settings. …”
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13705
Autism-Like Behavior and Epigenetic Changes Associated with Autism as Consequences of In Utero Exposure to Environmental Pollutants in a Mouse Model
Published 2015-01-01“…Brain samples from Mn, Pb, and VPA treated and control animals were evaluated for changes in CpG island methylation in promoter regions and associated changes in gene expression. The Chd7 gene, essential for neural crest cell migration and patterning, was found to be hypomethylated in each experimental animal tested compared to water-treated controls. …”
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13706
A Method for Tomato Ripeness Recognition and Detection Based on an Improved YOLOv8 Model
Published 2024-12-01“…Additionally, the BiFPN (Bidirectional Feature Pyramid Network) module is introduced to replace the traditional PANet connection, which achieves efficient feature fusion across different scales of tomato skin color, size, and surrounding environment and optimizes the expression ability of the feature map. Finally, an Inner-FocalerIoU loss function is designed and integrated to address the difficulty of ripeness classification caused by class imbalance in the samples. …”
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13707
The Alteration and Clinical Significance of Th22/Th17/Th1 Cells in Patients with Chronic Myeloid Leukemia
Published 2015-01-01“…Plasma IL-22, IL-17, and IFN-r concentrations were measured by ELISA. AHR and RORC mRNA expressions were examined by RT-PCR. The frequencies of Th22, Th17, and Th1 cells, along with the expression of specific transcription factors RORC and AHR, were significantly decreased in ND patients compared with healthy controls, while all these abnormality recovered in CP patients. …”
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13708
Epigenetic Properties of Compounds Contained in Functional Foods Against Cancer
Published 2024-12-01“…Epigenetics encompasses reversible and heritable genomic changes in histones, DNA expression, and non-coding RNAs that occur without modifying the nucleotide DNA sequence. …”
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13709
FBP1 Is an Interacting Partner of Menin
Published 2014-01-01“…This investigation therefore places menin in a pathway that regulates MYC gene expression and has important implications for the biological function of menin.…”
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13710
Serum CEACAM1 Elevation Correlates with Melanoma Progression and Failure to Respond to Adoptive Cell Transfer Immunotherapy
Published 2015-01-01“…However, the clinical management of melanoma is severely hampered by the absence of effective screening tools. The expression of the CEACAM1 adhesion molecule on melanoma cells is a strong predictor of poor prognosis. …”
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13711
Yoon Suk Yeol’s policy towards Japan: Reasons for changing approach and prospects
Published 2024-10-01“…On the other hand, Yoon’s administration emphasizes its intention to develop future-oriented relations with Tokyo, expressing its readiness not to raise controversial issues of the historical past. …”
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13712
Molecular genetic basis of epidermolysis bullosa
Published 2023-03-01“…The formation of reduced proteins or decrease in their level leads mainly to functional disorders, forming mild or intermediate severe phenotypes. Absent protein expression is a result of null genetic variants and leads to structural abnormalities, causing a severe clinical phenotype. …”
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13713
Sufentanil enhances the cortical neurogenesis of rats with traumatic brain injury via PI3K/AKT signal pathway
Published 2025-02-01“…The results showed Sufentanil significantly decreased the oxidative stress and inflammation levels, increased melatonin and BDNF levels, protected the nerve cells from damage, enhanced the regeneration of immature or mature neurons and the p-AKT protein expression in the cortex, and boosted MWT in TBI rats. …”
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13714
Exosomes and microRNAs as mediators of the exercise
Published 2025-01-01“…Environmental factors, such as physical exercise, can modulate miRNA expression and induce targeted changes in gene transcription. …”
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13715
Discussion on the mechanism of HER2 resistance in esophagogastric junction and gastric cancer in the era of immunotherapy
Published 2025-12-01“…This review examines the mechanisms of drug resistance in HER2-positive G/GEJ cancer, the primary mechanisms of resistance explored include alterations in the HER2 receptor itself, such as mutations and changes in expression levels, as well as downstream signaling pathways, and interactions with the tumor microenvironment (TME). …”
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13716
Rare Case of Gut-associated Lymphoid Tissue Carcinoma in the Sigmoid Colon of a Very Elderly Patient: A Case Report
Published 2025-01-01“…Immunohistochemical analysis showed lost expression of mismatch repair proteins, MLH1 and PMS2, consistent with the tumor immunohistochemistry profile. …”
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13717
A transgenic mouse line with a 58 kb fragment deletion shows skeletal defects
Published 2025-02-01“…Immunohistochemical examination demonstrated reduced chondrocyte proliferation, apoptosis and increased collagen X expression in the 58 kb-/- growth plate. Our data showed a lower number of osteoblasts and osteoclasts in the 58 kb-/- as compared to WT. …”
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13718
Exploratory study on the efficacy of topical pan-JAK inhibitor in ocular and skin GVHD in a sclerodermatous GVHD mouse model
Published 2025-01-01“…Signal transducer and activator of transcription (STAT)1, STAT3, and STAT5A phosphorylation was significantly increased in the back skin and eyelids of vehicle-treated GVHD mice; topical delgocitinib administration significantly reduced the expression of these phosphorylated STAT molecules. Delgocitinib eye drops significantly attenuated corneal epithelial damage, MG acinar depletion, and inflammatory cells infiltration in GVHD mouse corneas. …”
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13719
Negative Affect, Type D Personality, Quality of Life, and Dysfunctional Outcomes of Total Knee Arthroplasty
Published 2019-01-01“…Contrarily, increased expressions of NA/SI at follow-up were predicted by NA (p=0.04) and rumination (p=0.05) at the baseline. …”
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13720
Epônimos em textos científicos: modelo de análise e aplicação no campo da Bibliometria
Published 2023-03-01“…Os principais resultados indicaram que os epônimos mais frequentes foram as três leis clássicas da Bibliometria (Lei de Bradford, Lei de Lotka e Lei de Zipf), seguidas por expressões eponímicas de outras áreas de conhecimento, tais como a Matemática e a Estatística, bem como a ocorrência da obliteração por incorporação advinda da não citação dos trabalhos originais que originaram os epônimos. …”
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