Enhancer regulatory networks globally connect non-coding breast cancer loci to cancer genes by Yihan Wang, Daniel A. Armendariz, Lei Wang, Huan Zhao, Shiqi Xie, Gary C. Hon

“…We observe BC-associated enhancers that directly or indirectly regulate the expression of cancer genes. We also find one-to-multiple and multiple-to-one network motifs where enhancers indirectly regulate cancer genes. …”
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Disfunción renal: fármacos, medios de contraste radiológicos y sistema renina angiotensina by José Antonio Chipi Cabrera, Julio Alexander Silveira Echavarría, Aliuska Naranjo Hernández, Darnelys Méndez Lemus, Giraldo Hurtado Báez

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tPA-MMP-9 Axis Plays a Pivotal Role in Mobilization of Endothelial Progenitor Cells from Bone Marrow to Circulation and Ischemic Region for Angiogenesis by Steve Leu, Yuan-Ji Day, Cheuk-Kwan Sun, Hon-Kan Yip

“…By day 14, in animals with CLI, expression levels of proangiogenic factors (CXCR4, SDF-1α, and VEGF) showed similar trends as circulating EPC levels. …”
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Synthesis of BiOI-TiO2 Composite Nanoparticles by Microemulsion Method and Study on Their Photocatalytic Activities by Yunfang Chen, Xiaoxin Xu, Jianzhang Fang, Guangying Zhou, Zhang Liu, Shuxing Wu, Weicheng Xu, Jinhui Chu, Ximiao Zhu

“…The BPA degradation could be approached by a pseudo-first-order rate expression. The observed reaction rate constant (kobs) was related to nanoparticles dosage and initial solution pH.…”
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Enhanced Chemical Insights into Fullerene Structures via Modified Polynomials by Ali N. A. Koam, Ali Ahmad, Raed Qahiti, Muhammad Azeem, Waleed Hamali

“…It emphasizes the polynomial nature of molecular features and gives numerics in algebraic expression. Particularly in this context, we describe multiple cages topologically based on the fullerene molecular form as polynomials, and several algebraic properties, including the Randić number and the modified polynomials of the first and second Zagreb numbers, are measured. …”
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Drug Target Investigation of <i>N</i>-<i>p</i>-Coumaroyl-<i>N</i>’-Caffeoylputrescine, a Naturally-Occurring Alkaloid Derived from <i>Saxifraga tangutica</i> by Chuang Liu, Jun Dang, Minchen Wu

“…An in vitro study on liver (HepG2) cells and breast (MCF-7) cancer cells revealed that PCC modulates HSP90AA1, subsequently affecting Mut-p53 expression, triggering a cascade effect that reduced adriamycin-induced drug resistance in cells. …”
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Acupuncture Alleviates CUMS-Induced Depression-Like Behaviors by Restoring Prefrontal Cortex Neuroplasticity by Peng Li, Wenya Huang, Yiping Chen, Muhammad Shahzad Aslam, Wenjing Cheng, Yang Huang, Wenjie Chen, Yanxun Huang, Xinnan Wu, Yining Yan, Junliang Shen, Tao Tong, Shuqiong Huang, Xianjun Meng

“…The prefrontal cortex expression, such as BDNF, PSD95, SYN, and PKMZ protein, was detected using the western blot and RT-PCR. …”
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Renewable Human Cell Model for Type 1 Diabetes Research: EndoC-βH5/HUVEC Coculture Spheroids by James M. Porter, Michael Yitayew, Maryam Tabrizian

“…Insulin secretion, metabolic activity, live cell fluorescence staining, and gene expression assays were used to compare the viability and functionality of spheroids composed of 100% beta-cells, 1 : 1 beta-cell/endothelial, and 1 : 3 beta-cell/endothelial. …”
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Comparative Study of Gleason 7 (3+4) and (4+3) Prostatic Adenocarcinomas with Prognostic Criteria and Immunohistochemical Profiles of AMACR, PSA and Ki-67 by Clarice F. E. M. Osório, Waldemar S. Costa, Carla B. M. Gallo, Luciano A. Favorito, Francisco J. B. Sampaio

“…Anti-AMACR protein expression was based on four scores: negative, weak, moderate and strong. …”
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Downregulation of Thromboxane A2 Receptor Occurs Mainly via Nuclear Factor-KappaB Signaling Pathway in Rat Renal Artery by Yaping Zhang, Man Mi, Yan-Hua Xie, Si-Wang Wang, Lars Edvinsson, Cang-Bao Xu

“…This decreased contractile response to U46619 was paralleled with decreased TP receptor mRNA and protein expressions in the renal artery smooth muscle cells. …”
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A proliferation-inducing ligand (APRIL) level among risk factors of ocular involvement in patients with Behçet’s disease by Rasha M. Ghaleb, Hanan S. Gad, Mohamed I. Abdallah, Zaki M. Zaki, Jehan A. Mahmoud

“…Little is known about the expression of a proliferation-inducing ligand (APRIL) in terms of ocular involvement in BD. …”
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Analysis of the transcriptional activity of model piggyBac transgenes stably integrated into different loci of the genome of CHO cells in the absence of selection pressure by L. A. Yarinich, A. A. Ogienko, A. V. Pindyurin, E. S. Omelina

“…When stable producer cell lines are obtained, the locus of transgene integration into the genome has a great influence on the level of its expression. Therefore, the identification of genomic loci ensuring a high level of protein production is very important. …”
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Prediction of some peroxidase functions in <i>Arabidopsis thaliana</i> L. by bioinformatic search by A. S. Tugbaeva, A. A. Ermoshin, I. S. Kiseleva

“…Peroxidases within each cluster had similar molecular weights and isoelectric points, common localization of expression, and similar functions. Thus, the use of bioinformatics, databases, and published data bring us to assumptions as to the functions of several A. thaliana class III peroxidases. …”
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Functional study on the regulation of adventitious root formation by PpSAT4 gene in peach rootstock ‘GF 677’ by HAO Lanlan, WANG Hong, ZHANG Fan, ZHANG Xuebing, YANG Yang

“…Analysis of cis-acting elements showed the presence of response elements such as light, auxin, and gibberellin in the PpSAT4 sequence. (2) The overexpression vector Pp- SAT4-CAM-FLAG was constructed and transformed P . domestica and A . thaliana, and the transgenic lines were obtained. (3) qRT-PCR analysis showed that the expression level of PpSAT4 in the transgenic lines was higher than that of the wild-type. …”
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Identifikasi Ekspresi Gen Myc pada Subkultur MCF-7 Breast Cancer Cell Line dengan Sel Punca by Yuastika Puspita Sari, Hirowati Ali, Aswiyanti Asri

“…Subjek penelitian akan diwakili oleh cell line MCF-7 dan Umbilical Cord Blood Mesenchymal Stem Cell (UCBMSC). Over expression Myc pada kanker payudara mengakibatkan sel kanker menjadi lebih invasif dan terjadi resistensi terhadap terapi hormonal. …”
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A multi-levels analysis to evaluate the toxicity of microplastics on aquatic insects: A case study with damselfly larvae (Ischnura elegans) by Lin Sun, Zhongyan Cheng, Mei Wang, Chao Wei, Haoyu Liu, Yuxia Yang

“…The results showed that the PS MPs had no significant effects on the body weight and survival rate, but led to behavioral inhibition. Furthermore, expression levels of some metabolites altered, such as nicotinic acid, fumaric acid, and stearic acid. …”
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ARTIFICIAL INTELLIGENCE AS A METHODOLOGICAL INNOVATION IN THE TRAINING OF FUTURE DESIGNERS: MIDJOURNEY TOOLS by Ivan M. Tsidylo, Chele Esteve Sendra

“….); the lack of skills in formulating a description of images through the expression of the main categories of visual art through the linguistic means of language, whether in English or in the mother tongue. …”
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Multiple Components of the VHL Tumor Suppressor Complex Are Frequently Affected by DNA Copy Number Loss in Pheochromocytoma by David A. Rowbotham, Katey S. S. Enfield, Victor D. Martinez, Kelsie L. Thu, Emily A. Vucic, Greg L. Stewart, Kevin L. Bennewith, Wan L. Lam

“…CNL significantly reduced gene expression and was associated with enrichment of gene targets controlled by HIF1. …”
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Connexin 43 Communication Channels in Follicular Dendritic Cell Development and in Follicular Lymphomas by Hajnalka Rajnai, Ivett Teleki, Gergo Kiszner, Nora Meggyesházi, Peter Balla, Tamas Vancsik, Gyorgyi Muzes, Judit Csomor, Andras Matolcsy, Tibor Krenacs

“…However, the inverse correlation between Cx43 expression and B cell proliferation seen in reactive germinal centers was not detected in follicular lymphomas. …”
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Bicarbonate Within: A Hidden Modulator of Antibiotic Susceptibility by Selvi C. Ersoy, Warren E. Rose, Richard A. Proctor

“…Mechanistically, bicarbonate appears to influence <i>mecA</i> expression and PBP2a production/localization, as well as key elements for PBP2a functionality, including the PBP2a chaperone PrsA, components of functional membrane microdomains (FMMs), and wall teichoic acid (WTA) synthesis. …”
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