Physiological and transcriptome analysis reveals the mechanism of Gymnocarpos przewalskii response to drought stress by Chao Du, Xinyu Ni, Mengjiao Yan, Qinghan Meng, Junying He

“…Comparative analysis identified 3,015 differentially expressed genes under osmotic stress. There were 2,134 and 1,739 DEGs enriched in 47 GO secondary categories and 129 KEGG pathways, respectively. 2 up-regulated DEGs were annotated to P5CS, a key enzyme in the biosynthesis of proline. 32 DEGs were annotated to various antioxidases and antioxidants. 81 DEGs were annotated to 8 plant hormone signaling pathways, in which the auxin and ABA signaling pathways exhibited dominant enrichment. 150 DEGs were annotated to 35 transcription factor families with the abundant enrichment of TF families containing WRKY, bZIP, ERF, bHLH, MYB, and NAC. …”
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Establishment of a bat lung organoid culture model for studying bat-derived infectious diseases by Mohamed Elbadawy, Nagisa Saito, Yuki Kato, Kimika Hayashi, Amira Abugomaa, Mio Kobayashi, Toshinori Yoshida, Makoto Shibutani, Masahiro Kaneda, Hideyuki Yamawaki, Kazuaki Sasaki, Tatsuya Usui, Tsutomu Omatsu

“…The generated BLO successfully recapitulated the characteristics of pulmonary epithelial structure and morphology. BLO expressed the entry receptors for coronavirus, Angiotensin-converting enzyme 2 (ACE2), and Transmembrane Protease Serine 2 (TMPRSS2), and alveolar type 2 cells were successfully sorted from BLO, which has an important role for the development of viral infection in the respiratory system. …”
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Breast Cancer Survivors’ Diet and Physical Activity Preferences and Barriers: How COVID-19 Changed the Intervention Landscape by Xin Chen, Chungyi Chiu, Helen Hoi Ting Cheung, Sylvia L Crowder, Xi Chen, Linda Trinh, Anna E Arthur

“…Results: There were 224 participants. Over half expressed interest in a BC research study related to diet and exercise. …”
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IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential by Feiya Sheng, Mi Li, Jia-Mei Yu, Si-Yu Yang, Liang Zou, Guan-Jun Yang, Le-Le Zhang, Le-Le Zhang

“…Interleukin-33 (IL-33) is a nuclear factor and member of the IL-1 cytokine family. IL-33 is mainly expressed by epithelial and endothelial cells and exerts its function through interaction with various immune cells, and binding to its receptor can form the IL-33/Suppression of tumorigenicity 2 (ST2) signaling pathway. …”
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Psoriasis increases the risk of Sjögren’s syndrome: evidence from a propensity score-matched cohort study and transcriptomic analysis by Zijian Kang, Yu Du, Ran Cui, Qian Wang, Miao Chen, Yu-Hsun Wang, James Cheng‐Chung Wei, Sheng-Ming Dai

“…Transcriptome data were analyzed to identify shared differentially expressed genes and pathways between the two diseases. …”
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Corticosteroid Phobia: A Key Barrier to Treatment in Young Women with Idiopathic Granulomatous Mastitis by Lin W, Wang Q, Liu J, Tan Q

“…Sources of drug information were also identified. Scores were expressed as mean ± standard deviation. Independent t-test was used to compare the TOPICOP item scores between different categorical variables.Results: A total of 50 IGM patients were included in the present study. …”
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Single-Cell RNA-Seq Uncovers Cellular Heterogeneity from Deep Fascia in Necrotizing Fasciitis Patients by Wang T, Zhang L, Chen W, Long Y, Zhang Y, Wang L, Hou Z

“…We aim to investigate the change of cells from deep fascia in response to NF by single-cell RNA-seq.Methods: Fascia samples from NF patients (NF group, NG, n = 3) and volunteer (control group, CG, n = 4) were obtained and we utilized scRNA-seq to observe the variation of cells and differentially expressed genes. Then, multiplex staining and multispectral imaging and immunohistochemistry were used to be further verified.Results: Our findings showed that three fibroblast subclusters (antigen-presenting Fib, mesenchymal Fib, and myoFib) and three macrophage subclusters (SPP1+ Mac0, IL1B+ Mac1, and SPP1+M2) were found to have increased proportions with distinct roles in NF patients. …”
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Computational and experimental study of swirling ring flow by A. A. Kishkin, Yu. N. Shevchenko, A. A. Zuev, D. A. Zhuikov

“…Assuming the symmetry axis of the flows using the integral form of writing the continuity equation, the relations are obtained in the form of two differential equations with expressed derivatives along the channel axis for the total pressure p* and the circumferential velocity constant Cu = UR (const — at the integration step). …”
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Effects of kelp phlorotannins on the growth, immunity, intestinal health and disease resistance against Vibrio splendidus of sea cucumber Apostichopus japonicus by Zhikai Zhang, Yan Chi, Yongheng Du, Feng Li, Ning Ma, Song Qin

“…The intestinal health of sea cucumbers was also enhanced by phlorotannins, as expressed by the higher intestine fold height, up-regulation of tight junction genes (ZO-1 and occludin) and down-regulation of two proinflammatory genes (interleukin 17 and transforming growth factor - beta). …”
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Comparison of conventional versus robotic-assisted total hip arthroplasty using the Mako system: An Italian retrospective study by Roberta Banchetti, Silvia Dari, Maria Elisabetta Ricciarini, Domenico Lup, Francesco Carpinteri, Fabio Catani, Patrizio Caldora

“…There was a significant difference in the length of hospital stay, expressed as number of days hospitalized, between the MAKO group (M = 5.14, SD = 1.98) and the standard group (M = 8.11, SD = 1.64) (t(105) = 15.30, P < 0.001). …”
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How much water vapour does the Tibetan Plateau release into the atmosphere? by C. Zheng, L. Jia, G. Hu, M. Menenti, M. Menenti, J. Timmermans

“…<p>Water vapour flux, expressed as evapotranspiration (ET), is critical for understanding the earth climate system and the complex heat–water exchange mechanisms between the land surface and the atmosphere in the high-altitude Tibetan Plateau (TP) region. …”
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Yoruba Epistemology, Art, Language and the Universe of Meanings: A Meta-Analysis by Michael O. Afolayan

“…Like in many Shakespearean plays, many truths are expressed in the acts of the jesters, not in the court of the privileged kings and pundits. …”
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Knowledge, attitude, and reasons for non-uptake of human papilloma virus vaccination among nursing students by Soni Chauhan, Surya Kant Tiwari, Vishal Dubey, Pragya Tripathi, Priyanka Pandey, Anuj Singh, Narendra Pal Singh Choudhary

“…Additionally, Hindu students had 2.44 times the odds of being willing to receive the vaccine (AOR = 2.44, 95% CI = 1.15–5.20). Most participants expressed willingness to receive the vaccine (62.0%), citing reasons such as not being sexually active (35.8%) and needing more information (18.2%) for non-uptake of the vaccine. …”
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The Relationship between Russian Identity and Political Polarization: The Role of Secure National Identification and National Narcissism by O.A. Gulevich, S.S. Kosimova

“…Participants appraised the extent to which fellow citizens with these views exhibit certain traits; expressed emotions towards them; evaluated their willingness to interact and collaborate on common issues and considered the acceptability of restricting their rights and opportunities. …”
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Burnout Syndrome among Emergency Physicians and Nurses in Abha and Khamis Mushait Cities, Aseer Region, Southwestern Saudi Arabia by Abdulghani M. Alqahtani, Nabil J. Awadalla, Safar A. Alsaleem, Awad S. Alsamghan, Mohammed Abadi Alsaleem

“…Healthcare professionals who reported a history of taking medications for sleep disorders expressed higher risk for burnout opposed to those with no history of sleep disorder medication (aOR=6.59; 95% CI: 2.08-20.81, p=0.001). …”
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Randomized, Open-Label Phase 2 Study of Apalutamide plus Androgen Deprivation Therapy versus Apalutamide Monotherapy versus Androgen Deprivation Monotherapy in Patients with Bioche... by Rahul Aggarwal, Joshi J. Alumkal, Russell Z. Szmulewitz, Celestia S. Higano, Alan H. Bryce, Angela Lopez-Gitlitz, Sharon A. McCarthy, Branko Miladinovic, Kelly McQuarrie, Shibu Thomas, Ke Zhang, Eric J. Small

“…Of the few biomarkers expressed in blood, EPHA3 was significantly associated with shorter time to PSA progression (P=0.02) in the overall population. …”
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Co-administration of Hibiscus sabdariffa linn and Daflon-500® mitigates weight loss, hyperglycemia, hematological and oxidative changes in male rats with type-2 diabetes by Aishat Omobolanle Olatunji, Root Oluwapelumi Alegbe, Suleiman Folorunsho Ambali, Muftau Shittu, Ganiu Jimoh Akorede, Abdulfatai Aremu, Afisu Basiru, Jamila Abdulhamid Atata, Kolawole Yusuf Suleiman, Charles Amoto Shuaibu

“…Conclusion: Hibiscus sabdariffa linn and Daflon-500® expressed substantial hypoglycemic, antioxidant, and hemato-protective effects.…”
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CD-1 mice females recognize male reproductive success via volatile organic compounds in urine by A. S. Khotskina, E. L. Zavjalov, E. P. Shnayder, L. A. Gerlinskaya, S. O. Maslennikova, D. V. Petrovskii, M. N. Baldin, A. L. Makas, V. M. Gruznov, M. L. Troshkov, M. P. Moshkin

“…At the same time, naive females, who did not participate in reproduction, assessed the urine of the successful males as more attractive, which was expressed in shorter Latency time of sniffs in the Olfactory test. …”
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The difference between young and older ducks: Amino acid, free fatty acid, nucleotide compositions and breast muscle proteome by Tiantian Gu, Mingcai Duan, Li Chen, Yong Tian, Wenwu Xu, Tao Zeng, Lizhi Lu

“…We found that 496 differentially expressed proteins (DEPs) were screened. GO and KEGG analysis mainly enriched in glycine, serine, and threonine metabolism, tyrosine metabolism, and pyruvate metabolism. …”
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Experiences, perceptions and ethical considerations of the malaria infection study in Thailand by Bhensri Naemiratch, Natinee Kulpijit, Supanat Ruangkajorn, Nicholas P. J. Day, Jetsumon Prachumsri, Phaik Yeong Cheah

“…We found that although compensation was a motivation for participation, this was secondary to it being beneficial to self (health checks; link to health networks; building merit) and others (medical research contribution; altruism). Participants expressed varied opinions regarding the requirement of a university degree as one of the inclusion criteria for MIST. …”
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