Phenylethanoid glycosides from traditional Mongolian medicine Cymbaria daurica alleviate alloxan-induced INS-1 cells oxidative stress and apoptosis by Ruyu Shi, Xing Li, Bing Gao, Chunhong Zhang, Minhui Li

“…According to the RNA-seq technology to identify the differentially expressed genes in INS-1 cells, the pathway of gene enrich the protective effect of C. daurica on oxidative stress. …”
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Development of an sRNA-mediated conditional knockdown system for Chlamydia trachomatis by Janina Ehses, Kevin Wang, Asha Densi, Cuper Ramirez, Ming Tan, Christine Sütterlin

“…To test for polar effects, we separately targeted the inclusion membrane proteins IncE and IncG, which are expressed from the incDEFG operon. Knockdown of IncE caused loss of IncE and its interacting host protein SNX6 at the inclusion membrane, without affecting IncG protein levels. …”
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Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway by Xiaolong Liu, Xuran Li, Guangyuan Wu, Pengfei Qi, Yanyan Zhang, Zhiyu Liu, Xinyue Li, Yu Yu, Xiangmei Ye, Yang Li, Dongguang Yang, Yueqiu Teng, Ce Shi, Xin Jin, Sen Qi, Yuting Liu, Shudan Wang, Ying Liu, Fenglin Cao, Qingran Kong, Zhenkun Wang, Hong Zhang

“…Full-length transcriptome sequencing was performed to identify the differentially expressed genes associated with HUMSC-sEVs treatment, followed by validation via real-time PCR and Western blot. …”
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Analysis of Biomolecular Changes in HeLa Cervical Cancer Cell Line Induced by Interaction with [Pd(dach)Cl₂] by Vanja Ralić, Maja D. Nešić, Tanja Dučić, Milutin Stepić, Lela Korićanac, Katarina Davalieva, Marijana Petković

“…Although a certain level of lipid peroxidation was detectable by SR FTIR spectroscopy and confirmed by an analysis of cellular lipids by matrix-assisted laser desorption and ionisation time-of-flight mass spectrometry, the oxidative stress is not a significant mechanism by which Pd(II) expresses the effect on the HeLa cells.…”
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Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from India by Jeffrey Pradeep Raj, Suraj Kallarakal Tomy, Amrutha Jose, Aadrika Kashyap, Joseph Varghese Kureethara, Tomy K Kallarakal

“…Approximately, 50% were unfamiliar with CR but 42.4% expressed willingness to participate in a future CR. …”
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Acceptability, feasibility and appropriateness of intensified health education, SMS/phone tracing and transport reimbursement for uptake of voluntary medical male circumcision in a... by Mitch M Matoga, Evaristar Kudowa, Mercy Tsidya, Jennifer Tseka, Beatrice Ndalama, Naomi Bonongwe, Esther Mathiya, Edward Jere, Dumbo Yatina, Blessings Kamtambe, Mina C Hosseinipour, Charles S Chasela, Sara Jewett

“…For feasibility, HCWs agreed that RITe was easy to implement, but expressed concerns that R (end-line median = 4, IQR: 2, 4) and Te (end-line median = 4, IQR: 4, 4), were unsustainable. …”
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Migration of primordial germline cells is negatively regulated by surrounding somatic cells during early embryogenesis in Drosophila melanogaster by N. V. Dorogova, A. S. Khruscheva, Iu. A. Galimova, D. Yu. Oshchepkov, D. E. Maslov, E. D. Shvedkina, K. A. Akhmetova, S. A. Fedorova

“…We screened for genes expressed in the epithelium surrounding PGC during early embryogenesis and affecting their migration. …”
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BINGO! Elevating Medical Physiology Tutorials Through Gamification by Kelsey Temprine Grellinger, Hong Phan, Maria Sheakley, Gerrit J. Bouma, Alexandra Bayer, Biren A. Shah

“…The games were rated as effective educational tools (average: 4.2) and valuable for applying physiology knowledge (average: 4.4) on diverse topics (average: 4.4). Students expressed a desire for continued BINGO use in future tutorials (average: 4.2). …”
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Highly Proliferative Immortalized Human Dental Pulp Cells Retain the Odontogenic Phenotype when Combined with a Beta-Tricalcium Phosphate Scaffold and BMP2 by Xiangfen Li, Liu Wang, Qin Su, Ling Ye, Xuedong Zhou, Dongzhe Song, Dingming Huang

“…The immortalized human dental pulp cells (iHDPCs) acquired long-term proliferative activity and expressed most HDPC markers. The iHDPCs maintained multiple differentiation potential and could be induced to differentiate into chondrogenic, osteogenic, and adipogenic cells in vitro. …”
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Near vision assessment for adults using the NIH Toolbox by John-Christopher A. Finley, Jerry Slotkin, Cindy J. Nowinski, Cindy J. Nowinski, Katy Bedjeti, Nicholas Volpe, Sandra Weintraub, Sandra Weintraub, Richard Gershon

“…Performance on the tablet-and chart-based near vision tests was expressed in logarithmic units. Chart-and tablet-based administration order was counterbalanced. …”
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Evaluation of a pilot family planning educational seminar and subsequent attitudes towards family planning among Muslim communities in Tanzania. by Alexandra A Cordeiro, Hajirah Gumanneh, Aneth Nzali, Valencia J Lambert, Amina Yussuph, Albert Kihunrwa, Yassin Mchondo, Ramadhan Mtita, Hidaya Yahaya, Samuel E Kalluvya, Joyce Wamoyi, Mehrunisha Suleman, Jennifer A Downs, Agrey H Mwakisole

“…Participants viewed the seminar as enlightening and expressed that it improved their knowledge about FP and enabled them to consider FP from both medical and Islamic faith-based viewpoints. …”
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TEACHERS’ PROFILE, MOTIVATION, APTITUDE, AND SATISFACTION IN A VIRTUAL UPSKILLING ENVIRONMENT by Dave E. Marcial, Jan Cynth Palama, Fredlie Bucog, Steven Binarao

“…Despite this skill gap, the respondents expressed high satisfaction with the online upskilling they received. …”
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Assessing molecular changes underlying isopropylated phenyl phosphate (IPP)-induced larval sensorimotor response deficits in zebrafish by Sunil Sharma, Alfredo Rojas, Abhishek Gour, Rosemaria Serradimigni, Connor Leong, Abhisheak Sharma, Subham Dasgupta

“…However, for eyes, mRNA sequencing showed 135 differentially expressed genes and these were enriched for several nervous system-associated pathways, including voltage gated ion channel activity, synaptic transmission and neurotransmitter signaling. …”
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Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs by Elias A. Said, Sumaya Al-Dughaishi, Wadha Al-Hatmi, Iman Al-Reesi, Mohammed S. Al-Balushi, Atika Al-Bimani, Juma Z. Al-Busaidi, Marwa Al-Riyami, Murtadha Al-Khabori, Salam Al-Kindi, Francesco A. Procopio, Shadia Al-Sinawi, Aliyaa Al-Ansari, Crystal Y. Koh, Khalid Al-Naamani, Ali A. Al-Jabri

“…They regulate and are expressed by some immune cells. We have recently demonstrated MK production by some human innate antigen-presenting cells (iAPCs), i.e., monocyte-derived dendritic cells (MDDCs) and macrophages stimulated through Toll-like receptor (TLR)-4, and plasmacytoid dendritic cells (pDCs) stimulated through TLR 7. …”
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Rehabilitation program for elderly to improve physical and cognitive activities using Nintendo Switch: A feasibility study in care settings by Andreia Maria Novo Lima, Maria Teresa Moreira, Maria Salomé Ferreira, Vítor Parola, Sandra Rodrigues, Ana Cristina Corucho Barbeitos Pinto, Telmo Lima Costa, Carla Sílvia Fernandes

“…Despite the high motivation, the usability of the Nintendo Switch was not ideal, although participants expressed enjoyment and interest in the activities. …”
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Association of dysautonomia and different risk factors in patients with Guillain-Barré syndrome in a tertiary hospital in the Philippines by Gerald T. Pagaling, Lowrence Precious C. Dichoso, Nikolai Gil D. Reyes, Mario B. Prado

“…Simple and multiple logistic regression analysis were conducted to determine the factors associated with dysautonomia and the relationships were expressed using odds ratio. Results 71 patients were included, and 49% developed dysautonomia. …”
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RANTES and Chemotactic Activity in Synovial Fluids From Patients With Rheumatoid Arthritis and Osteoarthritis by Joanna Stanczyk, Marek L. Kowalski, Janina Grzegorczyk, Barbara Szkudlinska, Marzanna Jarzebska, Marek Marciniak, Marek Synder

“…The chemoattractive effect of RA SF was more pronounced on neutrophiles than on lymphocytes. RA SF expressed high RANTES levels (145±36pg/mL), while OA SF was characterised by only trace amount of this chemokine (2±1 pg/mL). …”
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Prognostic importance of human leukocyte antigen DRβ1 gene and protein tyrosine phosphatase nonreceptor Type 22 gene polymorphism in rheumatoid arthritis by Pramod Kumar Verma, Usha Singh, Shyam Kumar Saraf, Narendra Kumar Singh

“…Contrary to this, some alleles of DRβ1 were significantly less expressed in RA such as DRβ1*07 (P = 0.000) and DRβ1*14 (P = 0.010). …”
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Human Muscle Progenitor Cells Displayed Immunosuppressive Effect through Galectin-1 and Semaphorin-3A by Séverine Lecourt, Yves Lepelletier, Valérie Vanneaux, Rafika Jarray, Thomas Domet, Françoise Raynaud, Réda Hadj-Slimane, Audrey Cras, Olivier Hermine, Jean-Pierre Marolleau, Jérôme Larghero

“…Our experiments revealed that myoblasts, in culture or in situ in human muscles, expressed and secreted Gal-1 and Sema-3A. Furthermore, myoblasts immunosuppressive functions were reverted by using blocking antibodies against Gal-1 or Sema-3A. …”
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Assessment Of Heavy Metals Concentration and Pollution Indices Of Surface Water In Enerhen River, Warri South LGA, Delta State, Nigeria by A. O. Egai, M. Paaru

“…SS3 HPI (5394.674), HEI (102.2192) and CD (95.21933), SS4 HPI (507.0053), HEI (20.39265), CD (13.39267) and SS5 HPI (568.5303), HEI (25.9153) and CD (18.9154) .The HPI indicated values >150 which expresses high concentration of heavy metal pollution. …”
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