The Effectiveness and Safety of Probiotic Supplements for Psoriasis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Preclinical Trials by Liuting Zeng, Ganpeng Yu, Yang Wu, Wensa Hao, Hua Chen

“…Preclinical studies showed that continuous intervention with oral probiotics can significantly improve the progression of psoriasis and reduce the expression of inflammatory factors. The meta-analysis showed that the PASI between two groups was of no statistical significance (SMD 1.83 [-0.41, 4.07], P=0.11). …”
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Androgenic Anabolic Steroids Cause Thiol Imbalance in the Vascular Endothelial Cells by Halszka Ponamarczuk, Maria Światkowska, Marcin Popielarski

“…The susceptibility of endothelial cells to AASs depends on the expression of androgen receptors, although cells without androgen receptors can also be affected by high doses of AASs to a limited extent. …”
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Policy and Culture: From Machiavelli’s Political Philosophy to Kipling’s Political Prophecies by K. M. Dolgov, E. I. Starikova

“…. - actively opposed any evil manifestations: evil ideas, evil words, evil doings, expressing in their masterpieces the highest ideals and values. …”
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Therapeutic Potential of Dental Pulp Stem Cell Secretome for Alzheimer’s Disease Treatment: An In Vitro Study by Nermeen El-Moataz Bellah Ahmed, Masashi Murakami, Yujiro Hirose, Misako Nakashima

“…We determined whether DPSCs can secrete the Aβ-degrading enzyme, neprilysin (NEP), and evaluated the effects of NEP expression in vitro by quantitating Aβ-degrading activity. …”
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Ethanol Extract of Sesamum indicum Linn. Inhibits FcεRI-Mediated Allergic Reaction via Regulation of Lyn/Syk and Fyn Signaling Pathways in Rat Basophilic Leukemic RBL-2H3 Mast Cell... by Hyun Ju Do, Tae Woo Oh, Kwang-Il Park

“…We examined the degranulation release and concentrations of inflammatory mediators. Additionally, the expressions of genes involved in the FcεRI and arachidonate signaling pathways were examined. …”
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Mechanism by Which Laser Irradiation Combined with Spirulina platensis Enhances FeSO4-Induced Ferroptosis in Salmonella Typhimurium and Listeria monocytogenes by SUN Jinyue, PAN Jianeng, CHEN Yiying, LIU Rencheng, ZHOU Wenwen

“…To explore the mechanism by which laser (L) irradiation combined with Spirulina platensis (SP) enhances ferroptosis induced by FeSO4 (Fe) in Salmonella enterica serovar Typhimurium (ST) and Listeria monocytogenes (LM), this study measured lipid peroxidation, reactive oxygen species (ROS), glutathione (GSH), morphological characteristics, cell membrane damage, and expression levels of key genes in the two foodborne pathogens after different treatments. …”
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RNA Relocation and Persistence of Nucleolus-Like Bodies at Mitosis in Benzo[a]Pyrene-Transformed Human Breast Epithelial Cells after Microcell-Mediated Transfer of Chromosomes 11 a... by Maria Luiza S. Mello, Mohamed H. Lareef, Benedicto C. Vidal, Jose Russo

“…The changes resulting from the transfer of these two chromosomes in tumorigenic MCF‐10F cells (BP1‐E cell line) were examined, since alterations in these chromosomes are involved in the expression of the transformed and tumorigenic phenotypes in the MCF‐10F cell series. …”
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A New Network-Based Strategy for Predicting the Potential miRNA-mRNA Interactions in Tumorigenesis by Jiwei Xue, Fanfan Xie, Junmei Xu, Yuan Liu, Yu Liang, Zhining Wen, Menglong Li

“…To facilitate the clinical cancer research, we proposed a network-based strategy to identify the cancer-related miRNAs and to predict their targeted genes based on the gene expression profiles. The strategy was validated by using the data sets of acute myeloid leukemia (AML), breast invasive carcinoma (BRCA), and kidney renal clear cell carcinoma (KIRC). …”
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Clustering Pattern and Functional Effect of SNPs in Human miRNA Seed Regions by Sha He, Haiyan Ou, Cunyou Zhao, Jian Zhang

“…Genetic variations in the seed regions have vital effects on gene expression, phenotypic variation, and disease susceptibility in humans. …”
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Exploring PANoptosis in head and neck cancer: A novel approach to cancer therapy by Li Wang, Baisheng Lin, Feixiang Wang, Zili Dai, Guofeng Xie, Jian Zhang

“…This study utilises transcriptomic and clinical data related to HNSC from the Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) databases. We developed a risk model based on PANoptosis-related genes through LASSO Cox regression analysis. …”
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Effect of Ultrafine Powderization and Solid Dispersion Formation via Hot-Melt Extrusion on Antioxidant, Anti-Inflammatory, and the Human Kv1.3 Channel Inhibitory Activities of Ange... by Yunyao Jiang, Jingpei Piao, Nan Liu, Jincai Hou, Jianxun Liu, Weicheng Hu

“…In addition, AGN-SD inhibited the production of prostaglandin E2 and intracellular reactive oxygen species and the mRNA expression of inducible nitric oxide synthase, cyclooxygenase-2, interleukin 1β, and interleukin 6. …”
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Communication System Using Natural Language for Robotic Laparoscope Guidance by Pan Yan, Bernhard Lukas, Fan Cheng, Beckendorf Lukas, Wilhelm Dirk, Feußner Hubertus, Groh Georg

“…A variety of different vocabulary or phrases may be used for expressing the same command. At the same time, surgical workflows may be highly dynamic - especially in emergency situations - and thus the system must be able to grasp the user’s intent both quickly and with high accuracy. …”
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Effects of high-intensity interval training on physical performance, systolic blood pressure, oxidative stress and inflammatory markers in skeletal muscle of spontaneously hyperten... by Thaynara Zanoni D'Almeida, Mariana Janini Gomes, Leticia Estevam Engel, Ines Cristina Giometti, Natalia Zamberlan Ferreira, Rafael Stuani, Camila Renata Corrêa, Robson Chacon Castoldi, Sarah Gomes Nunes, Andreo Fernando Aguiar, Anthony César Castilho, Marina Politi Okoshi, Francis Lopes Pacagnelli

“…The following variables were measured in the tibialis anterior (TA) muscle: gene expression of the NADPH oxidase complex (NOX2, NOX4, p22phox, p47phox) and the NF-kB pathway (NF-kB and Ik-B), lipid peroxidation (malonaldehyde; MDA), protein carbonylation, hydrophilic antioxidant capacity (HAC) and pro-inflammatory cytokines (IL-6 and TNF-α).…”
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Simulation Study on the Impact Response of Barrels with Different Rifling Profiles during Bullet Engraving by Zhifang Wei, Yangyang Cheng, Zhiwei Wang, Yanpeng Lin

“…First, feature suppression by expression based on a uniform parametrized template was used to perform parametric modeling of a gun barrel with rectangular, trapezoidal, multiarc, and multilateral-arc rifling profiles. …”
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Blasting Vibration Generated by Breaking-Blasting Large Barriers with EBBLB by Wang Zhen-xiong, Gu Wen-bin, Liang Ting, Liu Jian-qing, Xu Jing-lin, Liu Xin

“…Furthermore, different approaches have been adopted to fit relationship between particle peak velocity (PPV) and distance from blasting center, comparative analysis of which provides the most appropriate relation expression to predict attenuation of PPV of vibration with distance from blasting center. …”
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E3 Ubiquitin Ligase CHIP Inhibits the Interaction between Hsp90β and MAST1 to Repress Radiation Resistance in Non-Small-Cell Lung Cancer Stem Cells by Bo Tan, Jingwei Zhang, Wen Wang, Haibo Ma, Yuanyuan Yang

“…Cancer and adjacent normal tissues of NSCLC patients were collected to determine expression of CHIP, Hsp90β, and MAST1. CD133+ cells were isolated from the NSCLC tissues and the lung cancer cell line A549 by flow cytometric sorting. …”
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Microvesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance Alveolar Type II Cell Proliferation and Attenuate Lung Inflammation in a Rat Model of Bronchopulmonar... by Ou Zhou, Jingyi You, Xiaochuan Xu, Jiang Liu, Huijun Qiu, Chang Hao, Wenjing Zou, Wenjie Wu, Zhou Fu, Daiyin Tian, Lin Zou

“…Compared with the LPS-exposed group, MVs restored the AT2 cell number and SP-C expression in vivo and promoted the proliferation of AT2 cells in vitro. …”
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Ovarian Seromucinous Borderline Tumor and Clear Cell Carcinoma: An Unusual Combination by Eriko Nakamura, Yuichiro Sato, Sayaka Moriguchi, Atsushi Yamashita, Takashi Higo, Yujiro Asada

“…Clear cell tumor cells were positive for Napsin A and p504S and focally positive for HNF1B but negative for ER and PgR. Loss of ARID1A expression was not observed in SMBTs, clear cell tumors, or endometriosis. …”
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Universality of human rights: general theoretical characteristics by Yu. A. Kholod

“…In essence, human rights cover a wide range of aspects, such as the right to life, liberty and security of the person, freedom of thought and expression, the right to education, work and an adequate standard of living. …”
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STAT3 inhibition ameliorates renal interstitial inflammation in MRL/lpr mice with diffuse proliferative lupus nephritis by Jianfen Zhu, Yijing Chen, Yulan Chen, Yinqiu Lv, Tianxin Chen

“…However, the specific therapy and mechanisms of AKI in DPLN remain to be explored.Methods The correlation between AKI and clinical pathological changes in DPLN patients was analyzed. Expression of STAT3 signaling was detected in MRL/lpr mice with DPLN using immunohistochemical staining and immunoblotting. …”
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