Complexity in Individual Trajectories toward Online Extremism by Z. Cao, M. Zheng, Y. Vorobyeva, C. Song, N. F. Johnson

“…By quantifying the trajectories that individuals follow on their journey toward expressing high levels of pro-ISIS support—irrespective of whether they then carry out a real-world attack or not—our findings can help move safety debates beyond reliance on static watch-list identifiers such as ethnic background or immigration status and/or postfact interviews with already convicted individuals. …”
Get full text

Principles of administrative legal proceedings in modern conditions: scientific and legal aspect by M. V. Dzhafarova

“…Based on the analysis of the existing scientific developments on this issue, the author supports and further develops the scientific position on determining the characteristic features inherent in the principles of administrative justice in the modern context, namely a) each principle is based on a certain idea, determined by the socio-legal and ideological values of public life, the state and law at this stage of development and functioning; b) the principles have an external expression, i.e. they are textually concentrated in the norms of administrative procedure legislation and reflect the content, essence and internal structure of administrative proceedings, the entire process of the dynamics of its implementation; c) the principles perform a safeguarding function, as they contribute to the main task of administrative proceedings to ensure the proper level of exercise and protection of individuals and legal entities of their rights, freedoms and legitimate interests from violations by public authorities; d) each principle should be logical and scientifically grounded, internally balanced, aimed at ensuring the orderly administration of justice in administrative cases, while not repeating the content of other principles of administrative justice and not contradicting each other.…”
Get full text

Elevation of Glucose 6-Phosphate Dehydrogenase Activity Induced by Amplified Insulin Response in Low Glutathione Levels in Rat Liver by Misako Taniguchi, Nobuko Mori, Chizuru Iramina, Akira Yasutake

“…These findings indicated that elevation of the G6PD activity in low GSH levels was caused by amplified insulin response for expression of the enzyme and accelerated turnover rate of the enzyme molecule.…”
Get full text

Droplet-based high-throughput 3D genome structure mapping of single cells with simultaneous transcriptomics by Honggui Wu, Maoxu Wang, Yinghui Zheng, X. Sunney Xie

“…Furthermore, our multi-omics joint assay, dscHi-C-multiome, enables precise cell type identification in the adult mouse brain and uncovers the intricate relationship between genome architecture and gene expression. Collectively, we developed the sensitive, high-throughput dscHi-C and its multi-omics derivative, dscHi-C-multiome, demonstrating their potential for large-scale cell atlas studies in development and disease.…”
Get full text

Représentations idéologiques d'une francophonie albertaine en mutation by Sylvie Roy, Fanny Macé

“…Dans cet article, à la lumière de la sociolinguistique pour le changement, nous examinons comment ces idéologies linguistiques influencent certains discours et pratiques d’étudiant·e·s en formation des maîtres ainsi que ceux de jeunes de la communauté d’expression française vivant en Alberta. Après avoir soumis nos données à une analyse de discours, nous constatons que la plupart des apprenant·e·s de FLS ne se perçoivent pas comme faisant partie intégrante de la francophonie. …”
Get full text

Paeoniflorin alleviates high glucose-induced endothelial cell apoptosis in diabetes mellitus by inhibiting HRAS-activated RAS pathway by Wenting Yu, Hongchun Jiang

“…In conclusion, Pae regulates the viability and apoptosis of HG-treated HUVECs by inhibiting the expression of HRAS.…”
Get full text

Formation of Tumorspheres with Increased Stemness without External Mitogens in a Lung Cancer Model by Juan Sebastian Yakisich, Neelam Azad, Rajkumar Venkatadri, Yogesh Kulkarni, Clayton Wright, Vivek Kaushik, Anand Krishnan V. Iyer

“…LTSs generated in this manner demonstrated several traits usually associated with increased stemness such as elevated expression of the stemness-associated marker Sox2 and increased chemoresistance to conventional anticancer drugs. …”
Get full text

Diet-Induced Adipocyte Browning by Oskar Wojciech Wiśniewski, Aleksander Rajczewski, Agnieszka Szumigała, Magdalena Gibas-Dorna

“…The adipocyte browning process is a phenomenon that consists in the molecular and morphological remodeling of preadipocytes or mature white adipocytes into multilocular beige fat cells expressing thermogenesis-associated genes. Adipocyte browning may occur physiologically, mainly upon cold or exercise stimulation. …”
Get full text

Specific Influences of Early Acoustic Environments on Cochlear Hair Cells in Postnatal Mice by Aoshuang Chang, Peng Chen, Shasha Guo, Nana Xu, Wenlu Pan, Hongzheng Zhang, Cuixian Li, Jie Tang

“…Compared with controls, no difference was found in the number and alignment of inner and outer hair cells or in the length of hair bundles after acoustic overstimulation. The expression and function of prestin, the motor protein of outer hair cells (OHCs), were specifically increased in OHCs activated by acoustic stimulation at postnatal days 7–11. …”
Get full text

La comunicación no verbal en la formación del profesorado de educación física: dificultades y limitaciones experimentadas by José Luis APARICIO HERGUEDAS, Antonio FRAILE ARANDA, María Rosario ROMERO MARTÍN, Sonia ASÚN DIESTE

Get full text

Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells by Jian-Xin Lin, Ning Du, Peng Li, Majid Kazemian, Tesfay Gebregiorgis, Rosanne Spolski, Warren J. Leonard

“…Here we show that STAT5 dimers are sufficient for NK cell development, whereas STAT5 tetramers mediate NK cell maturation and the expression of maturation-associated genes. Unlike the defective proliferation of Stat5 DKI CD8+ T cells, Stat5 DKI NK cells have normal proliferation to IL-15 but are susceptible to death upon cytokine withdrawal, with lower Bcl2 and increased active caspases. …”
Get full text

Forecast of Freight Volume in Xi’an Based on Gray GM (1, 1) Model and Markov Forecasting Model by Fan Yang, Xiaoying Tang, Yingxin Gan, Xindan Zhang, Jianchang Li, Xin Han

“…Then, the corresponding time sequence and expression of restore value of Xi’an freight volume can be attained by determining parameters, so as to obtain the gray forecast values of Xi’an’s freight volume from 2009 to 2013. …”
Get full text

Streptomyces sp. MUM 195J: A Promising Probiotic for Controlling Vibrio parahaemolyticus Infection in Aquaculture by Joanna Xuan Hui Goh, Loh Teng-Hern Tan, Jodi Woan-Fei Law, Giva Kuppusamy, Janaranjani M, Kooi-Yeong Khaw, Wei Hsum Yap, Kok-Gan Chan, Vengadesh Letchumanan, Learn-Han Lee, Bey-Hing Goh

“…Following that, molecular analyses were employed to examine the changes in gene expression. In essence, Streptomyces sp. MUM 195J emerges as a promising probiotic strain that demonstrates a strong inhibitory effect against V. parahaemolyticus. …”
Get full text

Plant Growth Promoting Rhizobacteria (PGPR): Reports on Their Colonization, Beneficial Activities, and Use as Bioinoculant by Dew Biswas, Amit Kumar Chakraborty, Vikas Srivastava, Arunava Mandal

“…Responding to the external environmental stimuli, they often modulate the expression of genes responsible for the transport of nutrients. …”
Get full text

Effects of Osseointegration by Bone Morphogenetic Protein-2 on Titanium Implants In Vitro and In Vivo by Fu-Yuan Teng, Wen-Cheng Chen, Yin-Lai Wang, Chun-Cheng Hung, Chun-Chieh Tseng

“…Moreover, the SMART group with a BMP-2 surface markedly promoted early alkaline phosphatase expression in the D1 cells compared with the other surface groups. …”
Get full text

Integrating mitochondrial and lysosomal gene analysis for breast cancer prognosis using machine learning by Huilin Chen, Zhenghui Wang, Jiale Shi, Jinghui Peng

“…We found that the overall immunoinfiltration of immune cells was decreased in the high-risk group, it was specifically noted that B cell mlMSGs activity remained diminished in high-risk patients. Finally, the expression and function of the key gene SHMT2 were confirmed through in vitro experiments. …”
Get full text

Direct Spinal Ventral Root Repair following Avulsion: Effectiveness of a New Heterologous Fibrin Sealant on Motoneuron Survival and Regeneration by Mateus Vidigal de Castro, Roberta Barbizan, Rui Seabra Ferreira, Benedito Barraviera, Alexandre Leite Rodrigues de Oliveira

“…Sciatic nerves were processed to investigate Schwann cell activity by p75NTR expression (4 weeks after surgery) and to count myelinated axons and morphometric evaluation (12 weeks after surgery). …”
Get full text

Jesus and the Feminine Genius. The Anthropological Relevance of the Encounters of Jesus with Women in the Fourth Gospel by Marc Timmermans

“… Pope John Paul II introduced the expression of the “Feminine Genius” in his Apostolic Letter Mulieris Dignitatem of 1988. …”
Get full text

Catechins and Caffeine Inhibit Fat Accumulation in Mice through the Improvement of Hepatic Lipid Metabolism by Chikako Sugiura, Shiho Nishimatsu, Tatsuya Moriyama, Sayaka Ozasa, Teruo Kawada, Kazutoshi Sayama

“…However, these activities were not observed in the other groups. FAS mRNA expression levels in the catechins + caffeine group were significantly lower than in the control group. …”
Get full text

A Proteomics Analysis to Evaluate Cytotoxicity in NRK-52E Cells Caused by Unmodified Nano-Fe3O4 by Yi-Reng Lin, Chao-Jen Kuo, Hugo You-Hsien Lin, Chin-Jen Wu, Shih-Shin Liang

“…From the statistical data of identified proteins, we believed that NPs treatment causes cell death and promotes expression of ras-related proteins. In order to avoid apoptosis, NRK-52E cell lines induce a series of protective effects such as glutathione related proteins to reduce reactive oxygen species (ROS), and chaperone proteins to recycle damaged proteins. …”
Get full text