Protective effects of Euphorbia heterophylla against testicular degeneration in streptozotocin-induced diabetic rats in relation to phytochemical profile. by Ahmed M Nagy, Heba A Fahmy, Mohamed F Abdel-Hameed, Rehab F Taher, Alaa M Ali, Mohamed M Amin, Sherif M Afifi, Tuba Esatbeyoglu, Mohamed A Farag, Abdelsamed I Elshamy

“…Treatment with EH-EtOH effectively mitigated the damage caused by STZ, as evidenced by restored testosterone (T4) levels and antioxidant capacity, reduced expression of pro-inflammatory cytokines, improved testicular microcirculation, and inhibition of apoptosis in the testes.…”
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Rapid Action of Aldosterone on Protein Levels of Sodium-Hydrogen Exchangers and Protein Kinase C Beta Isoforms in Rat Kidney by Somchit Eiam-Ong, Mookda Chaipipat, Krissanapong Manotham, Somchai Eiam-Ong

“…Aldosterone increased NHE protein expression mostly in the medulla. PKCβI immunostaining intensity was increased in the glomeruli, renal vasculature, and thin limb of the loop of Henle, while PKCβII was reduced. …”
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The impact of public hearings on decision making on the merger of municipalities in the Moscow region by E. P. Shitova

“…The purpose of this article is to determine the actual influence of citizens, their opinions, suggestions made by them, the expression of consent or disagreement on the issue being considered at the hearing on the final decision. …”
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High-fat diet triggers transcriptomic changes in the olfactory bulb by Young-Kook Kim, Danbi Jo, Seoyoon Choi, Juhyun Song

“…We found differences in the expression of protein-coding and non-coding RNAs involved in insulin, lipid metabolism, neurogenesis, serotonin, dopamine, and gamma-aminobutyric acid–related signaling in the olfactory bulb of HFD-fed mice compared to control mice. …”
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EKONOMINĖS IR KULTŪRINĖS VERTYBĖS: PANAŠUMAI IR SKIRTUMAI by Valdas Pruskus

“…ECONOMICAL AND CULTURAL VALUES: SIMILARITIES AND DIFFERENCIES Valdas Pruskus Summary The article discusses peculiarities of economical and cultural values and specific features of their expression. With the help of a phenomenon of an art museum as an example of cultural and economical values the author tries to define the main peculiarities of the above mentioned values. …”
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Deep weighted survival neural networks to survival risk prediction by Hui Yu, Qingyong Wang, Xiaobo Zhou, Lichuan Gu, Zihao Zhao

“…In the medical field, using gene expression data to build deep survival neural network models significantly improves accurate survival prognosis. …”
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IL-1β-Induced Matrix Metalloprotease-1 Promotes Mesenchymal Stem Cell Migration via PAR1 and G-Protein-Coupled Signaling Pathway by Ming-Siou Chen, Cheng-Yu Lin, Yun-Hsuan Chiu, Chie-Pein Chen, Pei-Jiun Tsai, Hwai-Shi Wang

“…The cDNA microarray data show that IL-1β induces matrix metalloproteinase-1 (MMP-1) expression. We then used quantitative real-time PCR and MMP-1 ELISA to verify the results. …”
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Identification of Osteosarcoma-Related Specific Proteins in Serum Samples Using Surface-Enhanced Laser Desorption/Ionization-Time-of-Flight Mass Spectrometry by Jianli Gu, Jitian Li, Manyu Huang, Zhiyong Zhang, Dongsheng Li, Guoying Song, Xingpo Ding, Wuyin Li

“…Two proteins showed a significantly different expression in OS serum samples from control groups. …”
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XGBoost-enhanced ensemble model using discriminative hybrid features for the prediction of sumoylation sites by Salman Khan, Sumaiya Noor, Tahir Javed, Afshan Naseem, Fahad Aslam, Salman A. AlQahtani, Nijad Ahmad

“…Abstract Posttranslational modifications (PTMs) are essential for regulating protein localization and stability, significantly affecting gene expression, biological functions, and genome replication. …”
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Postnatal Hematopoiesis and Gut Microbiota in NOD Mice Deviate from C57BL/6 Mice by Dina Silke Malling Damlund, Stine Broeng Metzdorff, Jane Preuss Hasselby, Maria Wiese, Mia Lundsager, Dennis Sandris Nielsen, Karsten Stig Buschard, Axel Kornerup Hansen, Hanne Frøkiær

“…Furthermore, a distinct splenic cell profile high in a granulocytic phenotype was evident in the neonatal NOD mice whereas neonatal C57BL/6 mice showed a profile rich in monocytes. Neonatal expression of Reg3g and Muc2 in the gut was deviating in NOD mice and coincided with fewer bacteria attaching to the Mucosal surface in NOD compared to C57BL/6 mice.…”
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Effect of Alkaloids from Nelumbinis Plumula against Insulin Resistance of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Mice by Yong Xie, Yi Zhang, Zebin Guo, Hongliang Zeng, Baodong Zheng

“…Further investigation indicated that NPA could inhibit IR by restoring the insulin receptor substrate-1 (IRS-1) and suppressing the expression of c-Jun N-terminal kinase (JNK) phosphorylation. …”
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Application of Mesoporous Silica Nanoparticle-Chitosan-Loaded BMP-2 in the Repair of Bone Defect in Chronic Osteomyelitis by Min Yi, Yu Nie, Chengyun Zhang, Bin Shen

“…In the BMSC test, we found that Chi-MSN could better promote their activity and osteogenesis, and the expression of osteogenesis-related genes (runt-related transcription factor 2 (RUNX-2), osteopontine (OPN), alkaline phosphatase (ALP), and osteopontine (OCN)) in the Chi-MSN group was higher. …”
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Decoding the mechanisms behind second primary cancers by Meiyuan Zeng, Anqi Lin, Aimin Jiang, Zhengang Qiu, Hongman Zhang, Shifu Chen, Mingyan Xu, Zaoqu Liu, Quan Cheng, Jian Zhang, Peng Luo

“…This review summarizes recent studies on the mechanisms of SPCs, including the roles of genomic changes after first primary cancer (FPC) treatments, stromal cell phenotypic and metabolic changes, hormone levels and receptor expression, immunosuppression, aberrant gene methylation, EGFR signaling, and cell-free DNA in SPC development. …”
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MiR-6869-5p Induces M2 Polarization by Regulating PTPRO in Gestational Diabetes Mellitus by Pingping Wang, Zhenzhi Ma, Zengyan Wang, Ximei Wang, Guifeng Zhao, Zengfang Wang

“…However, the altering effect of miR-6869-5p on immunity and placental microenvironment in gestational diabetes mellitus is largely unknown. In our study, the expression of miR-6869-5p was documented to be significantly decreased in placenta-derived mononuclear macrophages, which was also negatively related to PTPRO. …”
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Human papillomavirus, vaginal microbiota and metagenomics: the interplay between development and progression of cervical cancer by Paul Leon-Gomez, Vanessa I. Romero, Vanessa I. Romero

“…The review also discusses microbiome-related gene expression changes in cervical cancer patients. However, further research is needed to validate these findings and explore additional microbiome alterations in cancer progression.…”
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Inference of a three-gene network underpinning epidermal stem cell development in Caenorhabditis elegans by Alicja Brożek, Arianna Ceccarelli, Andreas Christ Sølvsten Jørgensen, Mark Hintze, Vahid Shahrezaei, Michalis Barkoulas

“…Our findings reveal TF regulatory relationships in seam cells and demonstrate a flexible mathematical framework for inferring gene regulatory networks from gene expression data.…”
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Effects of Renal Denervation on Ouabain-Induced Hypertension in Rats by Minna Tang, Jialu Hu, Wenshu Li, Ningzhi Zhang, Sisi Ning, Yan Yan, Zhaoqiang Cui

“…RDN also reduced the thickening of aortic tunica media and downregulated the expression of proliferating cell nuclear antigen (PCNA) in the thoracic aorta induced by ouabain. …”
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Evidence of Maintenance Tagging in the Hippocampus for the Persistence of Long-Lasting Memory Storage by Micol Tomaiuolo, Cynthia Katche, Haydee Viola, Jorge H. Medina

“…The proposed maintenance tagging has several characteristics: (1) the tag is transient and time-dependent; (2) it sets in a late critical time window after an aversive training which induces a short-lasting LTM; (3) exposing rats to a novel environment specifically within this tag time window enables the consolidation to a long-lasting LTM; (4) a familiar environment exploration was not effective; (5) the effect of novelty on the promotion of memory persistence requires dopamine D1/D5 receptors and Arc expression in the dorsal hippocampus. The present results can be explained by a broader version of the behavioral tagging hypothesis and highlight the idea that the durability of a memory trace depends either on late tag mechanisms induced by a training session or on events experienced close in time to this tag.…”
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The Economics of Immortality: The Demi-Immortal Oriental, Enlightenment Vitalism, and Political Economy in Dracula by J. Jeffrey Franklin

“…This character type began appearing with increasing frequency in the early nineteenth century for a range of specific historical reasons stemming from the Enlightenment, the Industrial Revolution, and Romanticism, but I will focus, secondly, on one specific historical precedent, namely “Enlightenment vitalism” and its subsequent expression as Mesmeric vitalism. Third, I will argue that in the character of the demi-immortal Oriental vitalism came to signify a type of eternal life in competition with the traditional Judeo-Christian afterlife, which rendered it necessarily damnable. …”
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Constipation at endocrine diseases by Yu. O. Shulpekova, A. G. Komova

“…Constipation is one of broad spectrum of gastro-intestinal hyperthyroidism manifestations, probably, related to change in expression of the genes regulating motility, decrease of autonomous nervous system excitability and dehydration. …”
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