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12661
Targeting Invasion: The Role of MMP-2 and MMP-9 Inhibition in Colorectal Cancer Therapy
Published 2024-12-01“…Gelatinases, specifically MMP-2 and MMP-9, play critical roles in the processes of tumor growth, invasion, and metastasis. Their expression and activity are significantly elevated in CRC, correlating with poor prognosis and lower survival rates. …”
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12662
Humic Acid Alleviates Low-Temperature Stress by Regulating Nitrogen Metabolism and Proline Synthesis in Melon (<i>Cucumis melo</i> L.) Seedlings
Published 2024-12-01“…HA significantly increased the expression of nitrogen metabolism and proline metabolism genes. …”
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12663
Axial Behaviour of Slender RC Circular Columns Strengthened with Circular CFST Jackets
Published 2018-01-01“…The strengthening effect of CFST jacketing decreased with the increase of L/D ratio and D/t ratio but showed little variation with higher SCC strength. An existing expression of load-bearing capacity for traditional CFST columns was extended to propose a formula for the load-bearing capacity of CFST jacketed columns, and the predictions showed good agreement with the experimental results.…”
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12664
Modulation of Adipose-Derived Mesenchymal Stem/Stromal Cell Transcriptome by G-CSF Stimulation
Published 2020-01-01“…Herein, microarray-based transcriptomic analysis shows that G-CSF stimulation in vitro results in modulation of various signaling pathways including ones related with the metabolism of hyaluronan (HA), conferring a profile of cell mobilization to ADSCs, mediated in a cell-intrinsic fashion in part by reducing CD44 expression and HA synthesis-related genes. Collectively, these data suggest a direct modulatory effect of G-CSF on ADSC function, potentially altering their therapeutic capacity and thus the design of future clinical protocols.…”
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12665
Fusion of Emotional Thinking and Mental Health of Students in Vocal Music Teaching
Published 2023-01-01“…They should focus on guiding students to experience and cultivate their abilities in a series of “processes” such as the emotion of vocal music, the teaching situation, the effect of listening, the creation of expression, and the aesthetic value. In addition, teachers should combine the teaching methods of transmission and inspiration, classroom teaching, and after-school training and combine relatively fixed teaching methods with flexible teaching methods to maximize the effectiveness of teaching.…”
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12666
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12667
Role of Injectable Platelet-Rich Fibrin in the Management of Soft and Hard Tissue Periodontal Regeneration in Dentistry: Protocol for a Systematic Review
Published 2025-01-01“… BackgroundInjectable platelet-rich fibrin (i-PRF) has the capacity to release great amounts of several growth factors, as well as to stimulate increased fibroblast migration and the expression of collagen, transforming growth factor β, and platelet-derived growth factor. …”
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12668
The Semantics of the Absurd: On German ‘Hermetic’ Poetry and Political Commitment after 1945
Published 2023-08-01“…But it was particularly in lyric poetry that a lucid and politically aware examination of the recent past took place and an expression of such considerations could be found. …”
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12669
Elites entre el mundo social y el cultural. El Club Social y el Ateneo de Córdoba (1870-1913)
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12670
E-cigarettes are not associated with post-acute COVID-19 syndrome among US adults
Published 2025-01-01“…E-cigarette use has already been associated with increased susceptibility to COVID-19 because of its effects on ACE2 receptor expression and inflammation, raising concern that it might worsen the long-term outcomes of COVID-19, including PCS. …”
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12671
Evidence that a STAT3 Mutation Causing Hyper IgE Syndrome Leads to Repression of Transcriptional Activity
Published 2019-01-01“…Th17 cell phenotyping revealed low levels of IL-17 expressing cells (0.3% of total CD4 T Cells numbers). …”
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12672
Brd7 loss reawakens dormant metastasis initiating cells in lung by forging an immunosuppressive niche
Published 2025-02-01“…Breast cancer cells harboring Brd7 inactivation also reprogram the surrounding immune microenvironment by downregulating MHC-1 expression and promoting a pro-metastatic cytokine profile. …”
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12673
Progesterone Increases Apoptosis and Inversely Decreases Autophagy in Human Hepatoma HA22T/VGH Cells Treated with Epirubicin
Published 2014-01-01“…The combination also caused a decrease in autophagy and in the expression of multidrug resistance-related protein 1 mRNA compared to epirubicin alone. …”
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12674
Wikireflexió: un espai d’aprenentatge virtual per a la reflexió i comprensió de les fonts teòriques
Published 2025-01-01“…D’acord amb les seves característiques, conflueixen elements educatius com la interacció entre estudiants i docents, aprofundir en els continguts de les matèries des del diàleg, potenciar la reflexivitat raonada, afavorir l’expressió d’idees pròpies, entre d’altres possibilitats. …”
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12675
Research Progress of ROS-Mitochondrial Pathway on Cardiovascular Protection of Tea Polyphenols
Published 2025-02-01“…From the perspective of ROS-mitochondrial pathway, the article elucidates how tea polyphenols behaved the beneficial effects against cardiovascular diseases by modulating the expression of mitochondrial fusion and fission proteins, reducing the opening of mitochondrial membrane permeability transition pore, maintaining cellular calcium homeostasis, mitigating mitochondrial DNA damage and regulating mitochondrial apoptosis signaling pathways. …”
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12676
Sinergias entre la cultura en movimiento y el movimiento (trans)feminista actual en Argentina
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12677
The Anti-Inflammatory Effect of Callicarpa nudiflora Extract on H. Pylori-Infected GES-1 Cells through the Inhibition of ROS/NLRP3/Caspase-1/IL-1β Signaling Axis
Published 2022-01-01“…After CN treatment, the expression levels of active caspase-1, PYCARD, and NLRP3 were remarkably decreased in the treatment groups compared with the model group. …”
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12678
Event-Related Potentials Elicited by Face and Face Pareidolia in Parkinson’s Disease
Published 2020-01-01“…Parkinson’s disease is associated with impaired ability to recognize emotional facial expressions. In addition to a visual processing disorder, a visual recognition disorder may be involved in these patients. …”
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12679
Automatic Construction of 3D Building Property Rights Model Based on Visual Programing Language in China
Published 2024-01-01“…In China, the pressure of land resource shortage, the increasing height and complexity of buildings in cities, and the inadequate spatial expression ability of two-dimensional (2D) real estate data pose challenges to government departments that use 2D real estate data as basic management elements. …”
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12680
New York Writing: Urban Art in Don DeLillo’s Underworld
Published 2009-12-01“…Son roman laisse entendre qu’à la fin du XXème siècle, le rôle de l’artiste est de répondre aux sollicitations visuelles et intellectuelles que les médias font subir au public, d’abord en plaçant les productions dominantes sous un jour ironique, et en transformant ensuite ces modes d’expression discrédités en de nouvelles formes culturelles. …”
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