A GIS-based Study of Wild Atlantic Way in the West of Ireland: Its Associated Organisations and Environmental impacts. by Leanne Leonard

“…As 67% (n=25) of survey respondents conclude there is little to no information available to tourists on the vulnerability of sites, the mapping of such important information is a productive expression of the raw data transformed into a comprehensible, user friendly map that can be quickly referred to upon arrival at each site.…”
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Bauhinia coccinea extract prevents memory loss induced by scopolamine through activation of antiapoptotic and antioxidant pathways in mice by Eunjin Sohn, Bu-Yeo Kim, Yu Jin Kim, Joo-Hwan Kim, Soo-Jin Jeong

“…EEBC also reversed the SCO-induced changes in apoptosis-related protein expression in brain tissues. Furthermore, EEBC significantly reduced malondialdehyde levels and activated catalase in SCO-administered brains. …”
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Role of androgen receptors in sexually dimorphic phenotypes in UBE3A-dependent autism spectrum disorder by Yuan Tian, Hui Qiao, KathrynAnn Odamah, Ling-Qiang Zhu, Heng-Ye Man

“…UBE3A-mediated degradation reduced androgen receptor (AR) levels in both sexes but only male mice showed significant dysregulation in the expression of AR target genes. Importantly, restoring AR levels in the brain normalized levels of AR target genes, and rescued the deficits in social preference, grooming, and memory in male UBE3A-overexpressing mice, without affecting females. …”
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Problems of interaction in the investigation of corruption crimes in the field of official activity and professional activity related to the provision of public services by Yu. K. Doroshenko

“…This activity by its nature is very complex, which finds its expression in its phasing. Among the latter, we suggest making a decision about the necessity and expediency of interaction, choosing the form and methods of interaction, procedural consolidation of the decision, direct interaction, and registration of the results of the indicated cooperation. …”
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Content Determination of Active Component in Huangqi Yinyanghuo Group and Its Effects on hTERT and Bcl-2 Protein in Osteosarcoma by Ying Tan, Lei Tan, Shuai Huang, Junfan Lu, Longtan Yu

“…To screen the optimal extraction process and content determination of active component of Huangqi Yinyanghuo group (HYG) and to study the effects of HYG on human telomerase reverse transcriptase (hTERT) and Bcl-2 protein in osteosarcoma (HOS) cells, providing the theoretical basis for clinical application of HYG in treatment of osteosarcoma, orthogonal design table L9(43) was used to design the extraction process of HYG, and icariin was taken as the investigation index to optimize the extraction process of HYG. 0.125, 0.25, 0.5, 1, 2, 4, and 8 μmol/L HYG were taken to act separately on logarithmic growth phase osteosarcoma HOS cells, CCK-8 assay was used to determine cell viability, and immunohistochemical SP assay was used to determine the expression of hTERT and Bcl-2 protein. Apoptosis rate was positively correlated with the dose of HYG, and the expressions of hTERT and Bcl-2 protein were significantly decreased with the prolonged duration of action. …”
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Mycoplasma pneumoniae drives macrophage lipid uptake via GlpD-mediated oxidation, facilitating foam cell formation by Takeshi Yamamoto, Miki Okuno, Koichi Kuwano, Yoshitoshi Ogura

“…Furthermore, the significant increase in the expression of oxidized lipid receptors involved in the uptake of this oxidized lipid indicates that the bacteria promote lipid uptake in infected macrophages. …”
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Changes in Lysine Methylation Contribute to the Cytotoxicity of Curcumin in Colon Cancer Cells by Roberta Santarelli, Paola Currà, Michele Di Crosta, Roberta Gonnella, Maria Saveria Gilardini Montani, Mara Cirone

“…Interestingly, curcumin also reduced mutp53 expression, suggesting that it could enhance the efficacy of other therapies, particularly in overcoming drug resistance mechanisms associated with mutp53. …”
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Caffeine Consumption Influences Lidocaine Action via Pain-Related Voltage-Gated Sodium Channels: An In Vivo Animal Study by Reham Alfaraj, Zainab Alabdulsalam, Zahrah Alfaraj, Hawraa Alsunni, Hussain Alhawaj, Omar Omar, Hatem Abuohashish

“…The molecular analysis of dorsal root ganglia suggested that CAF upregulated the mRNA expression of the Nav1.3, Nav1.7, and Nav1.8 sodium channel subtypes. …”
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Corneal Epithelial Removal with a Newly Designed Epithelial Brush by Ho Seok Chung, Seung Hwan Moon, Soon-Suk Kang, Minseop Kim, Hun Lee, Hungwon Tchah, Jae Yong Kim

“…In the Ocu group, epithelia were significantly recovered at 18, 24, and 50 hours compared with immediately after removal, and in the blade and Amo groups, epithelia were significantly recovered only at 50 hours after epithelial removal. The expression levels of PCNA and pHSP27 did not differ among three groups. …”
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BMP9 induces postnatal zonal stratification of immature articular cartilage through reconfiguration of the existing collagen framework by Miles Anderson-Watters, Ilyas M. Khan

“…We found that stromelysin-1 (metalloproteinase-3, MMP3) gene expression was consistently upregulated, whilst other MMP transcript levels were unchanged or reduced. …”
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Democracia, equilibrio informativo y pedagogía electoral. Análisis de la función orientadora del periódico regional La Patria en las elecciones locales de octubre de 2019 by Miguel Orlando Alguero Montaño

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Revisiting the role of IL-27 in obesity-related metabolic diseases: safeguard or perturbation? by Jinyang An, Donghua Fu, Ximei Chen, Conghui Guan, Conghui Guan, Lingling Li, Jia Bai, Haihong Lv, Haihong Lv

“…This article provides a comprehensive review of the latest findings on IL-27 expression and signal transduction in the regulation of immune inflammatory cells, as well as its implications in obesity and other related metabolic diseases. …”
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Adipose-Derived Stem Cell Transplantation Attenuates Inflammation and Promotes Liver Regeneration after Ischemia-Reperfusion and Hemihepatectomy in Swine by Zhihui Jiao, Yajun Ma, Xiaoning Liu, Yansong Ge, Qianzhen Zhang, Boyang Liu, Hongbin Wang

“…In addition, the ADSCs enhanced the expression of the anti-inflammatory IL-10, regenerative factors including HGF, Cyclin D1, and proliferating cell nuclear antigen (PCNA), and angiogenic factors like VEGF, ANG-1, and ANG-2. …”
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Red Light Mitigates the Deteriorating Placental Extracellular Matrix in Late Onset of Preeclampsia and Improves the Trophoblast Behavior by Jakara Griffin, John G. Krolikowski, Kenisha Kounga, Janine Struve, Agnes Keszler, Brian Lindemer, Michelle Bordas, Grant Broeckel, Nicole L. Lohr, Dorothee Weihrauch

“…Moreover, 670 nm irradiation restored expression of Transforming Growth Factor (TGFβ) and Placental Growth Factor (PLGF) to levels observed in trophoblasts cultured on healthy placental ECM. …”
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The Balance of Th1/Th2 and LAP+Tregs/Th17 Cells Is Crucial for Graft Survival in Allogeneic Corneal Transplantation by Shang Li, Jing Yu, Chungang Guo, Ying Jie, Zhiqiang Pan

“…The frequencies of Foxp3+Tregs, GARP+Tregs, and LAP+Tregs in the survival group were significantly higher than those in the rejection group. And the expression trend of CD4+LAP+ T cells and CD4+GARP+ T cells was consistent. …”
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EVENT AS A TRANSFORMATION OF EVERYDAY LIFE MODUS OF SOCIAL BEING by Y. G. Boreiko

“…In turn the event serves as a way of being existence, has a singular character, an individual expression, identifies elements that do not fit into the usual framework of everyday life. …”
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Unveiling cell-type-specific microRNA networks through alternative polyadenylation in glioblastoma by Mert Cihan, Greta Schmauck, Maximilian Sprang, Miguel A. Andrade-Navarro

“…A significant finding was the disconnection between differential APA events and gene expression alterations, indicating that APA operates as an independent regulatory mechanism. …”
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An Integrated Database for Exploring Alternative Promoters in Animals by Feiyang Xue, Yuqin Yan, Weiwei Jin, Haotian Zhu, Yanbo Yang, Zhanhui Yu, Xuewen Xu, Jing Gong, Xiaohui Niu

“…Abstract Alternative promoter (AP) events, as a major pre-transcriptional mechanism, can initiate different transcription start sites to generate distinct mRNA isoforms and regulate their expression. At present, hundreds of thousands of APs have been identified across human tissues, and a considerable number of APs have been demonstrated to be associated with complex traits and diseases. …”
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Coping strategies of fathers and siblings of children with cancer: a literature review by Teresa Rea, Vincenza Sansone, Andrea Zibaldo, Anna Bellingrath, Assunta Guillari

“…The three categories have in common the expression of contrasting feelings by each member of the family that generates changes in roles and responsibilities.Conclusions Further studies are needed to better understand how nurses can lead a family centred care approach to improve the general familiar management and coping strategies.…”
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Models of waveguides combining gradient and nonlinear optical layers by S. E. Savotchenko

“…The paper aims to develop a theory of composite optically nonlinear gradedindex waveguides with an arbitrary profile, within which it is possible to obtain exact analytical expressions for surface waves and waveguide modes in an explicit form. …”
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