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  1. 12561

    Neurobehavioral plasticity in the rodent gustatory system induced by regular consumption of a low-calorie sweetener during adolescence by Clare M. Mathes, Sarah J. Terrill, Juan P. Taborda-Bejarano, Sandrine Chometton, Mallory J. Witt, Gaurikka Mendiratta, Emily G. Gilman, Delenn R. Hartswick, Bo M. Anderson, Lindsey A. Schier

    Published 2025-01-01
    “…The anterior tongue had fewer fungiform taste papillae, and the circumvallate papillae had a reduced anterior to posterior span and diminished expression of genes involved in sweet reception, sweet and bitter intracellular signaling, fructose transport, and cellular progeneration in the Ace-K-exposed rats. …”
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  2. 12562

    Reorganisation of chromatin during erythroid differentiation by A. A. Khabarova, A. S. Ryzhkova, N. R. Battulin

    Published 2019-02-01
    “…Deciphering the mechanisms that coordinate shifts in gene expression revealed a critical role of three-dimensional chromatin structure in the regulation of gene activity during lineage commitment. …”
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  3. 12563

    Microglia-secreted TNF-α affects differentiation efficiency and viability of pluripotent stem cell-derived human dopaminergic precursors. by Shirley D Wenker, María Isabel Farias, Victoria Gradaschi, Corina Garcia, Juan Beauquis, María Celeste Leal, Carina Ferrari, Xianmin Zeng, Fernando J Pitossi

    Published 2023-01-01
    “…This long-lasting response was associated with Tumour necrosis factor alpha expression in microglial cells. In vitro, conditioned media from activated BV2 microglial cells increased cell death, decreased Tyrosine hydroxylase-positive cells and induced morphological alterations on human neural stem cells-derived dopaminergic precursors at two differentiation stages: 19 days and 28 days. …”
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  4. 12564

    Photochemical Treatment of Drosophila APCs Can Eliminate Associated Viruses and Maintain the APC Function for Generating Antigen-Specific CTLs Ex Vivo by Jun Ye, Chunxia Yang, Zeling Cai, Weixing Shi, Hong Yu

    Published 2018-01-01
    “…UVADEX treatment is sufficient to inactivate insect viruses but does not affect the expression of MHC class I molecules and costimulation molecules on Drosophila APCs. …”
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  5. 12565

    (5E,7E)-4,5,6 Trihydroxy-3-(hydroxymethyl)tetrahydro-2H-pyran-2-ylheptadeca-5,7-dienoate from Euclea crispa (L.) Inhibits Ovarian Cancer Cell Growth by Controlling Apoptotic and Me... by Chella Perumal Palanisamy, Bo Cui, Hongxia Zhang, Selvaraj Jayaraman, Ponnulakshmi Rajagopal, Vishnu Priya Veeraraghavan

    Published 2022-01-01
    “…The protein that is responsible for the death of cells (Bcl-2 and Bcl-xL) was reduced (p<0.05), while the protein expression of p53 and caspase-9 was increased (p<0.05) in compound 2-treated HO-8910 cells. …”
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  6. 12566

    Sargachromenol from Sargassum micracanthum Inhibits the Lipopolysaccharide-Induced Production of Inflammatory Mediators in RAW 264.7 Macrophages by Eun-Jin Yang, Young Min Ham, Kyong-Wol Yang, Nam Ho Lee, Chang-Gu Hyun

    Published 2013-01-01
    “…It also significantly inhibited the protein expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) in a dose-dependent manner in LPS-stimulated macrophage cells. …”
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  7. 12567

    Engineered CRISPR-Cas9 for Streptomyces sp. genome editing to improve specialized metabolite production by Duck Gyun Kim, Boncheol Gu, Yujin Cha, Jeonghan Ha, Yongjae Lee, Gahyeon Kim, Byung-Kwan Cho, Min-Kyu Oh

    Published 2025-01-01
    “…Cas9-BD and similarly modified dCas9-BD have been successfully employed for simultaneous biosynthetic gene cluster (BGC) refactoring, multiple BGC deletions, or multiplexed gene expression modulations in Streptomyces. We also demonstrate improved secondary metabolite production using multiplexed genome editing with multiple single guide RNA libraries in several Streptomyces strains. …”
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  8. 12568

    Gamma Radiation-Induced Damage in the Zinc Finger of the Transcription Factor IIIA by XiaoHong Zhang, YuJi Miao, XiaoDan Hu, Rui Min, PeiDang Liu, HaiQian Zhang

    Published 2016-01-01
    “…These results indicate that the zinc finger motif is a target domain for gamma radiation, which may decrease 5S rRNA expression via impairment of the zinc finger motifs in TFIIIA.…”
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  9. 12569

    Negative Effects of SIGIRR on TRAF6 Ubiquitination in Acute Lung Injury In Vitro by Feng Tian, Qiang Lu, Jie Lei, Yunfeng Ni, Nianlin Xie, Daixing Zhong, Guang Yang, Shaokui Si, Tao Jiang

    Published 2020-01-01
    “…Our results found that SIGIRR negatively regulated TRAF6 ubiquitination and such SIGIRR inhibition could enhance the TRAF6 expression in both alveolar epithelial cells (AECs) and alveolar macrophage cells (AMCs). …”
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  10. 12570

    Automatic Implementation of Fuzzy Reasoning Spiking Neural P Systems for Diagnosing Faults in Complex Power Systems by Haina Rong, Kang Yi, Gexiang Zhang, Jianping Dong, Prithwineel Paul, Zhiwei Huang

    Published 2019-01-01
    “…An FRSN P system offers an intuitive illustration based on a strictly mathematical expression, a good fault-tolerant capacity, a good description for the relationships between protective devices and faults, and an understandable diagnosis model-building process. …”
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  11. 12571

    Effect of 3-hydrazinylquinoxaline-2-thiol hydrogel on skin wound healing process in diabetic rats by Jehan Barakat Alamre, Huda Alkreathy, Ahmed S. Ali, Abdelbagi Alfadil, Sahar S. Alghamdi

    Published 2024-08-01
    “…We examined the wound closure rate, expression of inflammatory factors, growth factors in addition to the histological analysis. …”
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  12. 12572

    Beneficial effects of baicalein on a model of allergic rhinitis by Liu Tao, Xu Jing, Wu Yungang, Li Xiaoxia, Ding Detao, Ma Dengdian, Yao Mengwei, Wei Wenzhong, Zhang Wei, Wang Shaohua, Yao Jing, Li Xiaoyu

    Published 2020-03-01
    “…Furthermore, baicalein inhibited the expression of STAT3 phosphorylation in the nasal mucosa. …”
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  13. 12573

    SOME CONSIDERATIONS ON THE TYPOLOGY OF PHILOSOPHICAL-ANTHROPOLOGICAL MODELS (TO THE PROBLEM OF VALUE IDENTIFICATIONS OF UKRAINIANS) by V. V. Mudrakov, O. S. Polishchuk

    Published 2018-12-01
    “…Originality is in the disclosure of anthropological models that correspond to the value functionality, that is, the determination and expression of the essence of a person. It is shown that certain projects, under the conditions of forced reformatting, by their value reduction are classified as inhuman. …”
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  14. 12574

    Protective Effects of Garlic and Cinnamon Oils on Hepatocellular Carcinoma in Albino Rats by Salah M. Aly, Hamdy A. Fetaih, Abeer A. I. Hassanin, Mosleh M. Abomughaid, Aliaa A. Ismail

    Published 2019-01-01
    “…The HCC-induced group showed a significant decrease in the body mass and a significant elevation in the liver weight, alpha-fetoprotein (AFP), liver enzymes, hepatic malondialdehyde (MDA), and p53 protein expression levels as well as genetic mutations in intron 5 of p53 gene in the form of Single-Nucleotide Polymorphisms (SNPs) and insertions. …”
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  15. 12575

    One-Step Formation of Chondrocytes through Direct Reprogramming via Polysaccharide-Based Gene Delivery by Qingtong Yu, Yan Wang, Xia Cao, Wenwen Deng, Michael Adu Frimpong, Jiangnan Yu, Ximing Xu

    Published 2019-01-01
    “…The induced chondrocytes were identified through toluidine blue, Safranin O, and the immunostaining. The expression level of collagen II was finally evaluated through western blot. …”
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  16. 12576
  17. 12577

    Conserved pattern-based classification of human odorant receptor multigene family by Sang Eun Ryu, Jisub Bae, Tammy Shim, Won-Cheol Kim, Kwangsu Kim, Cheil Moon

    Published 2024-11-01
    “…Furthermore, we found that the CMC correlated with both ligand responses and ectopic expression patterns, highlighting its relevance to OR function. …”
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  18. 12578

    A Rare Case of Grey Zone Lymphoma Successfully Treated with Brentuximab Vedotin and R-CHP Chemotherapy by Rajiv M. Mallipudi, Lance Alquran, Vishnu A. Shenoy, Lori A. Leslie, John A. Conti

    Published 2019-01-01
    “…Given her strong CD30 expression, she underwent 6 cycles of R-BV-CHP (rituximab, brentuximab vedotin, cyclophosphamide, doxorubicin, and prednisone) chemotherapy and achieved complete response (CR) both clinically and radiographically. …”
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  19. 12579

    Pancreatic Inflammatory Pseudotumor-Like Follicular Dendritic Cell Tumor by Madison Mograbi, Michael S. Stump, David T. Luyimbazi, Mohammad H. Shakhatreh, Douglas J. Grider

    Published 2019-01-01
    “…Positivity for CD45 and CD68 in the larger spindled cells points to an inflammatory pseudotumor subtype and co-expression of CD21, CD23, and CD35 were indicative of follicular dendritic differentiation. …”
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  20. 12580

    Comprehensive Overview of Ketone Bodies in Cancer Metabolism: Mechanisms and Application by Ziyuan Liang, Lixian Deng, Xiaoying Zhou, Zhe Zhang, Weilin Zhao

    Published 2025-01-01
    “…Nonetheless, numerous questions remain regarding the expression of key metabolic genes across different tumors, the regulation of their activities, and the impact of individual KBs on various tumor types. …”
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