LEAPS Vaccine Incorporating HER-2/neu Epitope Elicits Protection That Prevents and Limits Tumor Growth and Spread of Breast Cancer in a Mouse Model by Ken S. Rosenthal, Sarah Stone, Gary Koski, Daniel H. Zimmerman

“…In this proof-of-concept study, the ability of J-HER to prevent or treat cancer was tested in the TUBO cell-challenged BALB/c mouse model for HER-2/neu-expressing tumors. The J-HER vaccine was administered as an emulsion in Montanide ISA-51 without the need for a more potent adjuvant. …”
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Characterization of Site-Specific Phosphorylation of NF-κB p65 in Retinal Cells in Response to High Glucose and Cytokine Polarization by Haoshen Shi, Elizabeth A. Berger

“…In contrast, IL-4 exhibited a suppressive effect on the phosphorylation of p65 sites in both cell types and promoted IκBα expression. Downstream inflammatory mediators were increased in response to proinflammatory cytokine treatment versus HG exposure. …”
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Integration of single-cell and bulk RNA-sequencing data to construct and validate a signature based on NK cell marker genes to predict immunotherapy response and prognosis in color... by Xiaoyu Qin, Wenjuan Xu, Jinxiu Wu, Ming Li

“…We integrated scRNA-seq data from four Gene Expression Omnibus (GEO) samples and performed Weighted gene correlation network analysis (WGCNA) based on 587 the Cancer Genome Atlas (TCGA) colorectal cancer samples to uncover NK cell-related genes. …”
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Synthesis of Arginase Inhibitors: An Overview by Maria Cristina Molaro, Chiara Battisegola, Marica Erminia Schiano, Mariacristina Failla, Maria Grazia Rimoli, Loretta Lazzarato, Konstantin Chegaev, Federica Sodano

“…In recent decades, the abnormal expression of ARG-1 or ARG-2 has been reported to be increasingly linked to a variety of diseases, including cardiovascular disease, inflammatory bowel disease, Alzheimer’s disease, and cancer. …”
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Apoptosis through Death Receptors in Temporal Lobe Epilepsy-Associated Hippocampal Sclerosis by Marcelo Ananias Teocchi, Lília D’Souza-Li

“…In addition, we evaluated the hippocampal relative mRNA expression of the two TNF receptors, TNFRSF1A and TNFRSF1B, in patients, being both upregulated (n=14; P<0.01 and P<0.04, resp.) when compared to the post mortem control group (n=4). …”
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Spatial transcriptomic analysis identifies epithelium-macrophage crosstalk in endometriotic lesions by Gregory W. Burns, Zhen Fu, Erin L. Vegter, Zachary B. Madaj, Erin Greaves, Idhaliz Flores, Asgerally T. Fazleabas

“…This study aimed to identify cell type-specific gene expression changes in superficial peritoneal endometriotic lesions and elucidate the crosstalk among the stroma, epithelium, and macrophages compared to patient-matched eutopic endometrium. …”
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Mesenchymal Stromal Cells Cultured in Serum from Heart Failure Patients Are More Resistant to Simulated Chronic and Acute Stress by Timo Z. Nazari-Shafti, Zhiyi Xu, Andreas Matthäus Bader, Georg Henke, Kristin Klose, Volkmar Falk, Christof Stamm

“…Cell survival, proliferation, metabolic activity, and apoptosis were quantified, and gene expression profiles of selected apoptosis and cell cycle regulators were determined. …”
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Free circulating ICAM-1 in serum and cerebrospinal fluid of HIV-1 infected patients correlate with TNF-α and blood-brain barrier damage by M. K. Sharief, M. Ciardi, M. A. Noori, E. J. Thompson, A. Salotti, F. Sorice, F. Rossi, A. Cirelli

“…Stimulation of endothelial cells by TNF-α induces the expression of intercellular adhesion molecule-1 (ICAM-1), which is an important early marker of immune activation and response. …”
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CONSIDERATION OF THE DESTABILIZING FACTORS INFLUENCE FOR INCREASING OF THE MEASUREMENTS ACCURACY OF A RANGEFINDER BASED ON STEREO IMAGES by V. L. Kozlov

“…Compensating polynomials for the optical system distortions of the first and second lenses of the stereo camera are experimentally determined.The range object expression from the stereo images taking into account the optical distortion compensation is obtained. …”
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Different In Situ Immune Patterns between Primary Tumor and Lymph Node in Non-Small-Cell Lung Cancer: Potential Impact on Neoadjuvant Immunotherapy by Zheng-Hao Ye, Hao Long, Ze-Rui Zhao

“…Multiplex immunofluorescence staining and multispectral imaging were used to evaluate the in situ immune patterns of T cells (CD3+) and cytotoxic T cells (CD8+) in terms of density, location (center of tumor (CT) and invasive margin (IM)), and the PD-L1 expression status of tumor cells and stromal T cells of paired PTs and mLNs in 38 stage III NSCLCs. …”
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MOVIMENTO BROWNIANO: APLICAÇÃO EM ESTRATÉGIAS DE BUSCA by Matheus Dias Carvalho, Ricardo de Carvalho Falcão, Antonio Marcos de Oliveira Siqueira

“…This paper structured partial differential equations governing this process for the immortal case of walker, and later found analytical solutions to these expressions. The representation of stationary state was also performed in graphical form, thus obtaining the distribution function of probability required. …”
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Characteristics of temper tantrums in 1–6-year-old children and impact on caregivers by Warangkana Prutipaisan, Issarapa Chunsuwan, Tippawan Hansakunachai, Paskorn Sritipsukho

“…Conclusion Tantrums are common in children aged 1–6 years, but their expression varies. Problematic tantrums were reported for approximately half of the children and significantly impacted their caregivers’ emotions. …”
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Body Weight Control by a High-Carbohydrate/Low-Fat Diet Slows the Progression of Diabetic Kidney Damage in an Obese, Hypertensive, Type 2 Diabetic Rat Model by Shuichi Ohtomo, Yuko Izuhara, Masaomi Nangaku, Takashi Dan, Sadayoshi Ito, Charles van Ypersele de Strihou, Toshio Miyata

“…Mediators of the renoprotection, specifically linked to obesity and body weight control, include a reduced renal inflammation and TGF-beta expression, together with an enhanced level of adiponectin. …”
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Design of Highly Adhesive Urchin‐Like Gold Nanostructures for Effective Topical Drug Administration and Symptomatic Relief of Corneal Dryness by Sandip Ghosh, Yun‐Han Su, Chia‐Jung Yang, Jui‐Yang Lai

“…In a rabbit model of corneal dryness, topical single‐dose nanoformulation (high quercetin‐functionalized gold nano‐urchins (NU‐Q(H))) demonstrated remarkable efficacy in stimulating tear production (30‐fold improvement), inhibiting inflammatory IL‐6 expression (49‐fold improvement), attenuating pathological angiogenesis (32‐fold improvement), and promoting nerve regeneration (18‐fold improvement) compared to high quercetin‐functionalized gold nanoparticles (NP‐Q(H)). …”
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Biochar and straw amendments drive microbial regulation of phosphorus dynamics in saline-irrigated cotton fields by Yang Ye, Xiaowen Guo, Yueyao Li, Wei Min, Huijuan Guo

“…Generally, under long-term salty irrigation, biochar, and straw amendments reduced soil salinity, raised soil P availability, decreased the expression of phosphorus cycling-related microbial genes, and improved soil characteristics. …”
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Clinical Characteristics of Patients with Antisocial Personality Disorder According to the Crime Types by Hasan KARADAG, M. Hakan TURKCAPAR, S. Olga GURIZ, Kadir OZDEL, Akfer KARAOGLAN KAHILOGULLARI

“…The State-Trait Anger Scale (STAS) was used to assess experience, expression, and control of anger. The main differences between crime groups were as follows: A head trauma history was more frequent in ASPD patients who had a crime history of physical assault. …”
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“Questão Social” na Realidade Brasileira: by Pedro Athayde, Felipe Barbosa Passos, Edson Marcelo Húngaro

“…O principal objetivo do texto é identificar e problematizar os limites dessas políticas frente às expressões da “questão social” tanto na trajetória histórica, quanto na atualidade brasileira. …”
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Modular cone-and-plate device for mechanofluidic assays in Transwell inserts by Daniel Chavarria, Kissamy A. Georges, Brian J. O’Grady, Khalid K. Hassan, Ethan S. Lippmann, Ethan S. Lippmann, Ethan S. Lippmann, Ethan S. Lippmann, Ethan S. Lippmann, Ethan S. Lippmann

“…Our results characterize how shear stress modulates passive barrier function and GLUT1 expression across the different BMEC lines. Overall, we anticipate this low cost mechanofluidic device will be useful to the mechanobiology community.…”
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Combining Ability of Pod Yield and Related Traits of Groundnut (Arachis hypogaea L.) under Salinity Stress by Md. Abul Kalam Azad, Md. Shah-E-Alam, Md. Abdul Hamid, Mohd Y. Rafii, M. A. Malek

“…Cross combinations showing high sca effects arising from parents with high and low gca values for any trait indicate the influence of nonadditive genes on their expression. Parents of these crosses can be used for biparental mating or reciprocal recurrent selection for developing high yielding varieties. …”
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Transient activation of YAP/TAZ confers resistance to morusin-induced apoptosis by Hoyeon Lee, Sang Woo Cho, Hyo Sun Cha, Kun Tae, Cheol Yong Choi

“…Furthermore, morusin-induced stress granule formation was significantly impaired in YAP/TAZ-depleted cells, suggesting a role in apoptosis resistance. Additionally, the expression of constitutively active MINK1 maintained YAP activation and reduced apoptosis, indicating that prolonged YAP activation can enhance resistance to cell death. …”
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