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12521
Diversity and distribution of mobile genetic elements in marine invertebrates genomes
Published 2017-04-01“…Mobile genetic elements (MGE) play an important role in genome structure and gene expression changes. All types of MGE are subdivided to two classes – retrotransposons and DNA-transposons. …”
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12522
Glucose Fluctuation Inhibits Nrf2 Signaling Pathway in Hippocampal Tissues and Exacerbates Cognitive Impairment in Streptozotocin-Induced Diabetic Rats
Published 2024-01-01“…Moreover, the morphological structure of hippocampal neurons was viewed through HE and Nissl staining, and transmission electron microscopy (TEM) was performed for ultrastructure observation. The protein expression levels of Nrf2, HO-1, NQO-1, Bax, Bcl-2, and Caspase-3 in the hippocampal tissues of rats were measured via Western blotting, and the mRNA expressions of Nrf2, HO-1, and NQO-1 were examined using qRT-PCR. …”
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12523
HHV8/EBV Coinfection Lymphoproliferative Disorder: Rare Entity with a Favorable Outcome
Published 2017-01-01“…HHV8/EBV-associated germinotropic lymphoproliferative disorder (GLD) is a challenging diagnosis given its rarity, the particular clinical presentation, and the lack of expression of markers usually used in establishing hematopoietic lineage. …”
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12524
Neuroprotective Activity of (-)-Epigallocatechin Gallate against Lipopolysaccharide-Mediated Cytotoxicity
Published 2016-01-01“…LPS treatment of macrophages induced expression of proinflammatory cytokines (TNF-α, IL-1β, and IL-6). …”
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12525
System Consolidation of Spatial Memories in Mice: Effects of Enriched Environment
Published 2013-01-01“…Following the probe test, regional expression of the inducible immediate early gene c-Fos was mapped by immunohistochemistry, as an indicator of neuronal activity. …”
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12526
Le Local, le Global, ou quelque part entre les deux ?
Published 2023-07-01“…Certains aspects de cet imaginaire sont observables à travers les diverses formes d’expression culturel que les festivals célèbrent et la manière dont leur contenu est (re)présenté, promu et consommé lors de ces événements. …”
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12527
Cellular and metabolic impacts of repeated sub-acute exposures to biomass-burning extracts in vitro
Published 2025-01-01“…Additionally, oxidative stress responses were more pronounced with increased lipid peroxidation and HMOX1, GCLC and CYP1A1 gene expression following repeated exposures. Metabolomics analyses of polar and lipid metabolites revealed changes related to energy production and consumption that emerge even after a single exposure at sub-acute levels and vary across different cell types representing the different tissues. …”
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12528
Association between Portal Vein Thrombosis and Survival in Non-Liver-Transplant Patients with Liver Cirrhosis: A Systematic Review of the Literature
Published 2015-01-01“…Meta-analyses were not conducted because the ways of data expression and lengths of follow-up were heterogeneous among studies. …”
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12529
Phytochemical Profiles and Anticancer Effects of Calophyllum inophyllum L. Extract Relating to Reactive Oxygen Species Modulation on Patient-Derived Cells from Breast and Lung Canc...
Published 2023-01-01“…Moreover, the extract exhibited inhibitory properties against migration and invasion at concentrations below the IC50, which corresponded to the expression of related genes. Notably, these effects correlated with the reduction of intracellular ROS levels. …”
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12530
Transcription factor specificity protein (SP) family in renal physiology and diseases
Published 2025-01-01“…A detailed analysis of their expression and cellular localization in the healthy human kidney is presented, highlighting their involvement in fatty acid metabolism, electrolyte regulation, and the synthesis of important molecules. …”
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12531
Nacionalismo militarista cotidiano en las escuelas de la dictadura chilena: usos rituales de los actos cívicos y las efemérides (1973-1980)
Published 2025-01-01“…Unlike other studies on the period, attention is paid to the ideological use and daily expression of school rituals and the transgressions carried out in the ritual dimension. …”
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12532
Construction of Two mCherry Plasmids (pXG-mCherry) for Transgenic Leishmania: Valuable Tools for Future Molecular Analysis
Published 2017-01-01“…We have constructed two plasmids expressing the red fluorescent protein mCherry with multiple cloning sites (MCS), adequate for N- and C-terminal fusion protein constructs. …”
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12533
Genomic Evidence for the Purging of Deleterious Genetic Variation in the Endangered North Atlantic Right Whale
Published 2024-12-01“…ABSTRACT The reduced genetic diversity and frequent inbreeding associated with small population size may underpin the accumulation and expression of deleterious mutations (mutation load) in some declining populations. …”
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12534
A tendência à neoinstitucionalização e o discurso religioso: elementos de análise para a reforma psiquiátrica
Published 2025-01-01“…Ao discutir o caso do Centro Vita e das comunidades terapêuticas, que expressam uma lógica semelhante, constatou-se que, se por um lado são locais destinados à morte dos improdutivos, por outro, encarnam moralidades e mentalidades atravessadas pelo discurso religioso, respondendo a necessidades subjetivas e existenciais que precisam ser tratadas com urgência, diante da crescente desfiliação social que assola os usuários de saúde mental e seus familiares.…”
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12535
Exploring the Stability and Capacity Characteristics of Mixed Traffic Flow with Autonomous and Human-Driven Vehicles considering Aggressive Driving
Published 2023-01-01“…Then, in a mixed traffic flow environment, a basic linear stability formula and capacity calculation expression are developed that consider the effects of vehicle order on the capacity. …”
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12536
Reverse-engineering the FLT3-PI3K/AKT axis to enhance TILs function and improve prognosis in ovarian and cervical cancers
Published 2025-01-01“…Seurat and Harmony were employed for batch correction and dimensionality reduction. FLT3 expression was mapped with spatial data from 10 × Genomics. …”
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12537
Loss of YTHDC1 m6A reading function promotes invasiveness in urothelial carcinoma of the bladder
Published 2025-01-01“…Here, we show that the m6A reader YTHDC1 is downregulated in muscle-invasive bladder cancer and is negatively correlated with the expression of epithelial‒mesenchymal transition genes. …”
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12538
Tissue‐resident memory T cells in diseases and therapeutic strategies
Published 2025-01-01“…Their unique retention and activation mechanisms, including interactions with local epithelial cells and the expression of adhesion molecules, enable their persistence and immediate functionality in diverse tissues. …”
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12539
Community radio and identity construction post-1994
Published 2022-10-01“…Set up after elections in 1994, expressly to create spaces for the articulation of marginal or “disadvantaged” groups, the community radio sector in South Africa has mushroomed, with nearly a hundred stations currently licensed. …”
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12540
Brincar como linguagem da criança: contribuições contemporâneas
Published 2017-10-01“…Acredita-se que a apropriação da teoria psicanalítica sobre o brincar e sua relação com a constituição do sujeito pode auxiliar na construção de espaços que proporcionam a capacidade lúdica e o agenciamento de narrativas criativas, a fim de que o sujeito possa expressar suas fantasias e dar sentido as suas vivências no laço social. …”
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