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12461
Ataxin-10 Inhibits TNF-α-Induced Endothelial Inflammation via Suppressing Interferon Regulatory Factor-1
Published 2021-01-01“…Overexpression of Ataxin-10 markedly inhibited the mRNA expressions of VCAM-1 and several cytokines including MCP-1, CXCL-1, CCL-5, and TNF-α; thus, it can also suppress monocyte adhesion to endothelial cells. …”
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12462
Empoderamiento femenino en el cómic portugués: un manifiesto por la igualdad de género
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12463
Treatment with Herbal Formula Extract in the hSOD1G93A Mouse Model Attenuates Muscle and Spinal Cord Dysfunction via Anti-Inflammation
Published 2022-01-01“…To evaluate the effects of HFE, we performed footprint behavioral tests, western blotting, and immunohistochemistry to detect protein expression and quantitative PCR to detect mRNA levels in the muscles and spinal cord of hSOD1G93A mice. …”
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12464
Medullary breast carcinoma: a pathogenic review and immunohistochemical study using tissue microarray
Published 2022-07-01“…Methods: This study aimed to review the clinicopathological features of MBCs diagnosed at the Department of Pathology, Singapore General Hospital and correlate them with immunohistochemical expression of hormonal markers and c-erbB-2, the basal markers p53, cytokeratin (CK) 14, epidermal growth factor receptor (EGFR) and 34BE12, and the follow-up outcome. …”
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12465
A NMR-Based Metabolomic Approach to Investigate the Antitumor Effects of the Novel [Pt(η1-C2H4OMe)(DMSO)(phen)]+ (phen = 1,10-Phenanthroline) Compound on Neuroblastoma Cancer Cells...
Published 2022-01-01“…NMR-based metabolomics demonstrated a peculiar alteration of the glutathione metabolism pathway and the diacylglycerol expression.…”
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12466
N7-methylguanosine modification in cancers: from mechanisms to therapeutic potential
Published 2025-01-01“…On the other hand, the aberrant expression of m7G modification-associated molecules is linked to clinicopathological characteristics, including tumour staging, lymph node metastasis, and unfavourable prognoses in patients with cancer, indicating their potential as tumour biomarkers. …”
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12467
Cidade e sociedade: análise da paisagem urbana do município de Santana do Araguaia-PA
Published 2021-03-01“…A paisagem urbana de determinado local compreende a expressão sociocultural da cidade, que se mostra através de uma diversidade de materialização e simbologia que se apresentam em cada lugar e se expande no contexto social, econômico e cultural. …”
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12468
Antigen Gene Transfer to Human Plasmacytoid Dendritic Cells Using Recombinant Adenovirus and Vaccinia Virus Vectors
Published 2005-01-01“…Recombinant adenoviruses (RAd) and recombinant vaccinia viruses (RVV) expressing tumour-associated antigens (TAA) are used as anti-tumour vaccines. …”
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12469
Thabo Mbeki’s Decolonial Idea of an African in the African Renaissance
Published 2022-11-01“…Colonialism, especially in its apartheid expression in South Africa, questioned the humanity of Black Africans, displaced them, and dispossessed them of their land. …”
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12470
Poly-ADP Ribosyl Polymerase 1 (PARP1) Regulates Influenza A Virus Polymerase
Published 2019-01-01“…Intriguingly, pharmacological inhibition of PARP1 enzymatic activity (PARylation) by 4-amino-1,8-naphthalimide led to a 4-fold increase in RdRP activity, and a 2.3-fold increase in virus titer. Exogenous expression of the natural PARylation inhibitor PARG also enhanced RdRP activity. …”
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12471
Targeting Transcriptional Regulators Affecting Acarbose Biosynthesis in <i>Actinoplanes</i> sp. SE50/110 Using CRISPRi Silencing
Published 2024-12-01“…These transcriptional regulatory genes were selected from previous experiments involving protein–DNA interaction studies or due to their expression profiles. Eleven genes affecting the yield of acarbose were identified. …”
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12472
Krait2: a versatile software for microsatellite investigation, visualization and marker development
Published 2025-01-01“…Microsatellite expansions play pivotal roles in gene expression regulation and are implicated in various neurological diseases and cancers. …”
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12473
Melanoma-derived cytokines and extracellular vesicles are interlinked with macrophage immunosuppression
Published 2025-01-01“…The analysis from altered cytokine profile data showed that melanoma-derived EVs upregulate Th2 cytokine expression in naïve macrophages, thereby contributing to the promotion of tumor-supporting functions. …”
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12474
Progesterone Changes the Pregnancy-Induced Adaptation of Cardiomyocyte Kv2.1 Channels via MicroRNA-29b
Published 2022-01-01“…In this study, we investigated the cardiac repolarization and ion channel expression in pregnant subjects and mice models and studied the effects of P4 administrations on these pregnancy-mediated adaptations. …”
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12475
Autoantibody Response to Murine Double Minute 2 Protein in Immunodiagnosis of Hepatocellular Carcinoma
Published 2014-01-01“…Immunohistochemistry (IHC) over tissue array slides was also performed to analyze protein expression of MDM2 in HCC and control tissues. The prevalence of autoantibodies against MDM2 was significantly higher than that in liver cirrhosis (LC), chronic hepatitis (CH), and normal human sera (NHS). …”
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12476
Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation.
Published 2025-01-01“…This process is associated with increased mitochondria-associated membranes (MAMs), mediated by the upregulated expression of sigma non-opioid intracellular receptor 1 (SIGMAR1). …”
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12477
Small Molecules Greatly Improve Conversion of Human-Induced Pluripotent Stem Cells to the Neuronal Lineage
Published 2012-01-01“…Key success factors for neuronal differentiation are the yield of desired neuronal marker expression, reproducibility, length, and cost. Three main neuronal differentiation approaches are stromal-induced neuronal differentiation, embryoid body (EB) differentiation, and direct neuronal differentiation. …”
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12478
Synergistical amelioration of muscle atrophy by modulating gut microbiota through the bioconversion of grape seed extract and whey using kefir lactic acid bacteria
Published 2025-06-01“…Supplementation with WDG synergistically ameliorated immobilization-induced sarcopenia by restoring grip strength, muscle weight, and the expression of genes related to muscle growth markers. …”
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12479
Radioiodine Labeled Anti-MIF McAb: A Potential Agent for Inflammation Imaging
Published 2007-01-01“…These results demonstrate the ability of radioiodinated anti-MIF McAb to measure in vivo inflammatory events represented by high expression of MIF and suggests that radiolabeled anti-MIF McAb warrants further investigation as a potential inflammation-seeking agent for imaging to detect inflammatory disorders.…”
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12480
The principle of national sovereignty through the lens of Saint Andrew's Day National Assembly
Published 2024-01-01“…In Serbia, it found its expression at the famous St. Andrew's Day National Assembly (1858). …”
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