Control of Cellular Differentiation Trajectories for Cancer Reversion by Jeong‐Ryeol Gong, Chun‐Kyung Lee, Hoon‐Min Kim, Juhee Kim, Jaeog Jeon, Sunmin Park, Kwang‐Hyun Cho

“…Abstract Cellular differentiation is controlled by intricate layers of gene regulation, involving the modulation of gene expression by various transcriptional regulators. Due to the complexity of gene regulation, identifying master regulators across the differentiation trajectory has been a longstanding challenge. …”
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Chemo-selective modification of cysteine residue: synthesis and application in the discovery of potential drug candidates by Yanyan Liao, Xuefeng Jiang

“…Cysteine (Cys), one of the less abundant AAs in many biological proteins, plays a vital role in the catalysis, signal transduction, and redox regulation of gene expression. In natural AAs (α-AAs) residues, Cys exhibits high nucleophilicity and low redox-active potential, making it a primary target for site-selective conjugation. …”
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Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma by Sonja Kabatnik, Xiang Zheng, Georgios Pappas, Sophia Steigerwald, Matthew P. Padula, Matthias Mann

“…Additionally, we observed substantial enrichment of immune-related proteins, reflecting high levels of cytotoxic T lymphocyte infiltration and elevated PD-1 expression. These findings suggest that pembrolizumab immunotherapy may be more effective than conventional chemotherapy for this patient. …”
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Analytical monodromy matrix method for small-signal stability analysis of grid-connected modular multilevel converter systems by Xiaofan Jia, Hua Ye

“…First, an analytical expression of the monodromy matrix (i.e., the state transition matrix over a period) for the LTP model of grid-connected MMC systems is constructed by applying the Chebyshev collocation method. …”
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LGBTQIAPN+fobia familiar em registros oficiais: uma análise de dados no Estado de Sergipe anteriores à criminalização da homofobia no Brasil by Moisés Menezes, Bruna Andrade Irineu

“…Dentre elas, destaca-se a relativização do discurso de ódio em nome da liberdade de expressão, conduta estimulada por entidades religiosas e lideranças políticas conservadoras, somadas às hierarquias sociais que tradicionalmente configuram a seara familiar. …”
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O rap de intervenção social em Maputo, Moçambique by Luca Bussotti, Julio Chinguai

“…Como base teórica para sustentar este estudo foi escolhida a teoria da indústria cultural de Adorno, complementada pela reinterpretação de Peterson e Berger, associada às formas de controlo que regimes a democracia limitada, tais como o moçambicano, exercem na liberdade de expressão, inclusivamente na esfera artística. …”
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The Role of Connexin-43 in the Inflammatory Process: A New Potential Therapy to Influence Keratitis by Chu-Yang Xu, Wen-Song Zhang, Hong Zhang, Yan Cao, Hong-Yan Zhou

“…We analyzed the effects of signaling molecules, such as innate immunity messengers, transcription factors, LPS, cytokine, inflammatory chemokines, and MMPs, on Cx43 expression during the inflammatory process. At the same time, we found that these signaling molecules play a critical role in the pathogenesis of keratitis. …”
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FlowMFD: Characterisation and classification of tor traffic using MFD chromatographic features and spatial–temporal modelling by Liukun He, Liangmin Wang, Keyang Cheng, Yifan Xu

“…As a solution, the authors propose FlowMFD, a novel Tor‐based application traffic classification approach using amount‐frequency‐direction (MFD) chromatographic features and spatial‐temporal modelling. Expressly, FlowMFD mines the interaction pattern between Tor applications and servers by analysing the time series features (TSFs) of different size packets. …”
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V.N. TATISHCHEV’S BUSINESS LETTERS IN THE GENRE ASPECT (BASED ON THE DOCUMENTS OF THE NATIONAL ARCHIVE OF THE REPUBLIC OF KALMYKIA) by Elena M. Sheptukhina

“…The genre specificity of the documents under study is manifested in the absence of self-nomination and mandatory reference to the addresser, in the use of a welcome address as a means of expressing the “addressee” properties, and the presence of optional elements.…”
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Making Systemic Risk Assessments Work: How the DSA Creates a Virtuous Loop to Address the Societal Harms of Content Moderation by Niklas Eder

“…Public actors, such as the European Commission, should refrain from defining substantive standards, too, as they are directly bound by freedom of expression guarantees. Instead, the Article argues, the Commission should foster a procedural framework, a “virtuous loop,” which empowers civil society and allows it to specify and refine the standards governing systemic risks over time. …”
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A qualitative study of motivations for non-suicidal self-injury in a sample of psychiatric outpatients in Singapore by Shazana Shahwan, Yunjue Zhang, Rajeswari Sambasivam, Say How Ong, Siow Ann Chong, Mythily Subramaniam

“…By contrast, a small subset of motivations served the interpersonal motivation of signaling one's distress, especially when the capacity for verbal expression was limited or attempts to verbalise distress were futile. …”
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Hyperreality, simulacra and simulations in virtual space as a phenomenon of «antisocial» theory by Jean Baudrillard by V. Novikov, S. Kovaleva

“….; b) communication in the virtual Internet is, in its essence, a simulation of communication, that is, its surrogate (simulacrum); in this case, the former contact form of communication is replaced by indirect – communication is carried out through social networks and messengers; c) there is a depletion of content and primitivization of expression of emotions, as in virtual communication uses a set of standard phrases, standard themes, emoticons, pictures, exchange of memes and other simulacra that are included in everyday social practices. …”
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In Sight of Mont Blanc: an Approach to Ruskin’s Perception of the Mountain by Laurence Roussillon-Constanty

“…Grand admirateur de Wordsworth, il prend soin par la suite de faire précéder chaque section de Modern Painters d’extraits de The Excursion, se faisant ainsi l’héritier d’une tradition romantique pour laquelle la montagne est le lieu privilégié de l’expression du sujet lyrique et le reflet d’une intériorité sans cesse en mouvement. …”
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LPI Optimization Framework for Target Tracking in Radar Network Architectures Using Information-Theoretic Criteria by Chenguang Shi, Fei Wang, Mathini Sellathurai, Jianjiang Zhou

“…Due to the lack of analytical closed-form expression for receiver operation characteristics (ROC), we employ two information-theoretic criteria, namely, Bhattacharyya distance and J-divergence as the metrics for target detection performance. …”
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Possible involvement of vitamin K insufficiency in the progression of cervical ossification of the posterior longitudinal ligament by Atsushi Kimura, Naoya Taki, Yukinori Hayashi, Yasuyuki Shiraishi, Tsukasa Ohmori, Katsushi Takeshita

“…Finally, supplementation caused an increase in the number of osteochondrogenic cells expressing Gla-rich protein, an inhibitor of ectopic calcification, and increased the circulating concentration. …”
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Photoperiod Sensitivity and Variability of Agromorphological Traits and Brix Content of Sweet Sorghum Cultivated in Burkina Faso under Two Sowing Dates by N. Sawadogo, J. Tiendrebéogo, G. Naoura, T. L. K. Béré, W. H. Tondé, B. Sawadogo, P. Bationo-Kando

“…In a general context of strong variations in the rainfall regime, it is, therefore, important to determine the effect of the sowing period on the expression of agromorphological traits and Brix content. …”
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Methylation Marks of Blood Leukocytes of Native Hucul Mares Differentiated in Age by T. Ząbek, E. Semik-Gurgul, T. Szmatoła, A. Gurgul, A. Fornal, M. Bugno-Poniewierska

“…A positive correlation was found between methylation states and gene expression in particular loci from our data set. Some of described age DMR-linked genes were also reported elsewhere. …”
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The role of DNA methylation in the disorders of bone metabolism by B. I. Yalaev, A. V. Tyurin, R. Y. Mirgalieva, R. I. Khusainova

“…It is possible that DNA methylation is one of these links and a mechanism for epigenetic regulation of gene expression. Evidence exists that this mechanism alongside regulatory miRNAs and post-translational modifications makes a significant contribution to the central processes of bone remodeling; however, the results of various studies vary greatly, and, therefore, there is a need to understand the significance of the accumulated data and to make them consistent. …”
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FAD2-DGAT2 Genes Coexpressed in Endophytic Aspergillus fumigatus Derived from Tung Oilseeds by Yi-Cun Chen, Yang-Dong Wang, Qin-Qin Cui, Zhi-Yong Zhan

“…Two transformants coexpressing vfFAD2 and vfDGAT2 showed a more than 6-fold increase in linoleic acid production compared to the original A. fumigatus strain, while a nearly 2-fold increase was found in the transformant expressing only vfFAD2. Our data suggest that vfDGAT2 plays a pivotal role in promoting linoleic acid accumulation in TAGs. …”
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Cerebrospinal fluid and serum cytokine profiles in severe viral encephalitis with implications for refractory status epilepticus: a retrospective observational study by Peipei Huang, Fan Yang, Ruirui Dong, Lijun Wen, Qiuling Zang, Dandan Song, Junshuang Guo, Yating Wang, Ruike Zhang, Zhiping Ren, Jinjin Qin, Junfang Teng, Wang Miao

“…Furthermore, we conducted a dynamic analysis of differences and correlations in the expression of cytokines among patients with SVE without seizures, those with controlled seizures, and those with RSE.ResultsWe included 161 patients with SVE; the incidence of seizures was 55.2%, and the mortality rate was 5.5%. …”
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