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12181
Racismo e julgamento social na internet: crianças e jovens negros como alvos
Published 2017-10-01“…Em síntese, o estudo traz contribuições para a análise do preconceito racial na internet contra jovens negros em conflito com a lei, possibilitando avaliar expressões do preconceito e da discriminação racial no Brasil. …”
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12182
Analysis of the effect of ALA-PDT on macrophages in footpad model of mice infected with Fonsecaea monophora based on single-cell sequencing
Published 2025-01-01“…After ALA-PDT treatment, the number of inflammatory cells decreased, while macrophages upregulated the expression of antigen-recognition-related genes, enhancing phagocytosis and autophagy-related biological functions.…”
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12183
Pyrogallol-Phloroglucinol-6, 6-Bieckol Restored Primary Cilia Length, Which Was Decreased by High-Fat Diet in Visceral Adipose Tissue, and Decreased Adipogenesis
Published 2022-01-01“…In addition, ECE or PPB elongated the cilia and decreased cyclin A2 and Cdk2 expression, which promote cell cycle reentry, and decreased the adipogenesis genes. …”
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12184
SEM-2/SoxC regulates multiple aspects of C. elegans postembryonic mesoderm development.
Published 2025-01-01“…Finally, SEM-2 appears to directly regulate the expression of hlh-8, which encodes a basic helix-loop-helix Twist transcription factor and plays critical roles in proper patterning of the M lineage. …”
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12185
Dendrimer functionalized folate-targeted gold nanoparticles for luciferase gene silencing in vitro: A proof of principle study
Published 2019-03-01“…The Au:G5D:FA nanocomplexes elicited excellent gene silencing in folate receptor expressing HeLa-Tat-Luc cells, decreasing significantly in the presence of excess FA ligand, indicating nanocomplex uptake by the mechanism of receptor mediation. …”
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12186
Race and gender biases in assessing pain intensity and medication needs among Chinese observers
Published 2025-02-01“…One hundred sixty-two Chinese participants completed a pain facial expression rating task assessing the level of pain intensity and the extent to which they believe the sufferer needs pain medication for East Asian, White, and Black sufferers, followed by a battery of questionnaires measuring their gender and race role expectation of pain. …”
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12187
Proinflammatory Mediators of Toxic Shock and Their Correlation to Lethality
Published 2010-01-01“…SEB induced low levels of TNFα, IL-1, IFNγ, MIP-2, and LPS synergized with SEB in the expression of these cytokines and that of IL-6 and MCP-1. …”
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12188
The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity
Published 2015-01-01“…Research has shown that SLPI exerts its anti-inflammatory activity by directly binding to NF-κB DNA binding sites and, in so doing, prevents binding and subsequent transcription of proinflammatory gene expression. In the current study, we demonstrate that SLPI can inhibit TNF-α-induced apoptosis in U937 cells and peripheral blood monocytes. …”
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12189
INLUENCE OF ALIEN GENETIC MATERIAL ON THE MANIFESTATION OF AGRONOMICALLY IMPORTANT TRAITS OF COMMON WHEAT (T. aestivum L.)
Published 2018-05-01“…Although resistance genes have a prolonged protective efect on donor plants against diverse populations of pathogens, the introgression of target loci into the genome of common wheat can result in a signiicant decrease in the eiciency of the genes – up to complete loss of expression. Additionally, alien gene introgression from wild relatives occurs through whole chromosome or chromosome arm substitutions, or long translocated fragments that, together with target loci, may contain genetic material that afects other agronomically important traits. …”
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12190
CTGF Attenuates Tendon-Derived Stem/Progenitor Cell Aging
Published 2019-01-01“…Recombinant CTGF also rescued decreased levels of cyclin D1 and CDK4 and reduced p27kip1 expression in aged TSPCs. Our results demonstrated that CTGF plays a vital role in TSPC aging and might be a potential target for molecular therapy of age-related tendon disorders.…”
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12191
Existence of Neural Stem Cells in Mouse Spleen
Published 2019-01-01“…The cultured cells were investigated for expression of the neural cell markers neuron-specific enolase (NSE) and neurofilament 150 kDa (NF-150) by immunocytochemistry. …”
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12192
El Códice Martínez Compañón como portador de epistemologías patrióticas andinas
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12193
Oridonin Relieves Angiotensin II-Induced Cardiac Remodeling via Inhibiting GSDMD-Mediated Inflammation
Published 2022-01-01“…After inhibiting the expression of GSDMD in cardiomyocytes by siRNA, it was found that Ang II-induced hypertrophy was attenuated. …”
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12194
Noncoding RNAs Associated with PPARs in Etiology of MAFLD as a Novel Approach for Therapeutics Targets
Published 2022-01-01“…We collected human and mouse MAFLD gene expression datasets available in GEO. We performed pathway enrichment analysis of total mRNAs based on KEGG repository data to screen the most potential pathways in the liver of MAFLD human subjects and mice model, and analyzed pathway interconnections via ClueGO. …”
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12195
Elucidating the Mechanisms of Acquired Palbociclib Resistance via Comprehensive Metabolomics Profiling
Published 2025-01-01“…The study indicated that there were 76 metabolite expression differences between SW620 cells with palbociclib resistance and the parental SW620 cells involving amino acids, glutathione, ABC transporters, and so on. …”
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12196
CAPS markers in plant biology
Published 2015-07-01“…Functional CAPS markers can be developed on the known sequence of a gene of interest for the analyses of its structure, function, expression, and regulation. CAPS closely linked to the gene of interest are especially helpful for Marker-Assisted Selection, and they are widely used in the breeding of wheat, barley, soybean, potato, tomato, and other crops for tolerance to various pathogens. …”
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12197
In Vitro Study of Combined Application of Bevacizumab and 5-Fluorouracil or Bevacizumab and Mitomycin C to Inhibit Scar Formation in Glaucoma Filtration Surgery
Published 2019-01-01“…Their effects on the levels of vascular endothelial growth factor (VEGF) in HUVECs, cell proliferation and migration in HTFs, and the expression of collagen type I alpha 1 (Col1A1) gene in HTFs were evaluated. …”
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12198
Natural regulatory T cells increase significantly in pediatric patients with parasitic infections: Flow cytometry study
Published 2023-07-01“…Background: The most accepted definition of regulatory T cells (Tregs) relies on the expression of several biomarkers, including CD4, CD25, and transcription factor, Foxp3. …”
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12199
Genetic variability and association studies for yield and pre-harvest sprouting traits in greengram [Vigna radiata (L.) Wilczek]
Published 2024-12-01“…High phenotypic variability suggests environmental influence on trait expression, especially in traits such as days to maturity and pod diameter. …”
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12200
Alterations of Amino Acids and Monoamine Metabolism in Male Fmr1 Knockout Mice: A Putative Animal Model of the Human Fragile X Mental Retardation Syndrome
Published 2001-01-01“…The results presented here provide the first evidence that lack of FMRP expression in FMRP knockout mice is accompanied by age-dependent, region-specific alterations in neurotransmission.…”
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