Upregulation of Soluble HLA-G in Chronic Left Ventricular Systolic Dysfunction by Line Lisbeth Olesen, Thomas Vauvert F. Hviid

“…The secondary aim was to examine associations between HLA-G gene polymorphisms influencing expression levels and LVSD. The 260 study participants were ≥75 years old, many with risk factors for heart disease or with known heart disease. …”
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Prefrontal contributions to mental resilience: Lessons from rodent studies of stress and antidepressant actions by Ryota Shinohara, Tomoyuki Furuyashiki

“…Rodent studies have also identified the roles of prefrontal D1 receptors as well as D1 receptor-expressing mPFC neurons projecting to multiple subcortical areas and dendritic spine formation in the mPFC for the sustained antidepressant-like effects of low-dose ketamine. …”
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Vitamin D Ameliorates Impaired Wound Healing in Streptozotocin-Induced Diabetic Mice by Suppressing Endoplasmic Reticulum Stress by Yi Feng Yuan, Sushant K. Das, Mao Quan Li

“…Vitamin D administration not only decreased the apoptosis rate but also increased cell viability. Furthermore, the expression of endogenous markers of ER stress was downregulated as a result of vitamin D treatment. …”
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The Correlation between Gut Microbiota and Serum Metabolomic in Elderly Patients with Chronic Heart Failure by Zhenhua Wang, Zhaoling Cai, Markus W. Ferrari, Yilong Liu, Chengyi Li, Tianzhang Zhang, Guorong Lyu

“…Blood and fecal samples were collected from 25 elderly patients with CHF and 25 healthy subjects. The expression of inflammatory factors in blood was detected by ELISA. 16S rDNA sequencing was used to analyze the changes in microorganisms in the samples. …”
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Interferon Lambda: A New Sword in Cancer Immunotherapy by Ahmed Lasfar, Walid Abushahba, Murugabaskar Balan, Karine A. Cohen-Solal

“…This particular pattern of response is controlled by the differential expression of the IFN-λ receptor, which, in contrast to IFN-α, should result in limited side effects in patients. …”
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Region sown areas portfolio optimization taking into account crop production economic risk by P. Hrytsiuk, T. Babych, O. Mandziuk

“…It has been determined that the profitability of crops with good precision follows Laplace distribution (double exponential distribution). The analytical expression for Value-at-Risk measures has been obtained using the Laplace distribution function. …”
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Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell Growth by Ting-Kai Leung, Chin-Feng Chan, Ping-Shan Lai, Chih-Hui Yang, Chia-Yen Hsu, Yung-Sheng Lin

“…Since malignant melanomas are known to have high HSP70 expression and iNO activity, the suppressive effects of cFIR on HSP70 and NO may warrant future interest in antitumor applications.…”
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Genetic markers in sheep meat breeding by A. V. Deykin, M. I. Selionova, A. Yu. Krivoruchko, D. V. Kovalenko, V. I. Truhachev

“…The problem of finding reliable communication between productivity features and genetic markers has not yet been solved, because productivity is a set of features (unlike, for example, monogenic diseases) and its expression depends on the balance between various physiological functions. …”
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Diversity of VIr’s collection of <i>Lupinus angustifolius</i> L. in the inf lorescence color by E. V. Vlasova, G. P. Egorova

“…Descriptions of some biotypes failed to agree with the data on any known gene’s phenotypic expression, which attested to the presence of new mutations, recombinations, or unstudied gene associations.…”
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Evaluation of the Response of Posttensioned Steel Frames with Energy Dissipators Using Equivalent Single-Degree-of-Freedom Systems by J. Luz Rivera, Arturo López-Barraza, Sonia E. Ruiz, Alfredo Reyes-Salazar

“…Several simple mathematical expressions are proposed. The first expression is useful to calculate modifying factors (FMEH) to relate EH of the ESDOFS with that of the MDOFS; the second is to determine the interstory drift (γ) as a function of the seismic intensity. …”
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Pitavastatin-attenuated cardiac dysfunction in mice with dilated cardiomyopathy via regulation of myocardial calcium handling proteins by Hu Wei, Jiang Wen-Bing

“…The ratio of phosphorylated phospholamban (PLB) to total PLB decreased significantly with the down-regulation of SERCA- -2a and ryanodine receptor (RyR2) expression. Pitavastatin was found to ameliorate the cardiac dysfunction in mice with dilated cardiomyopathy by reversing the changes in the ratios of phosphorylated PLB to total PLB, SERCA-2a and RyR2 via reducing the plasma AngII concentration and the expressions of myocardium angiotensin II type 1 receptor (AT1R) and protein kinase C (PKC)b2. …”
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Concomitant Alpha- and Gamma-Sarcoglycan Deficiencies in a Turkish Boy with a Novel Deletion in the Alpha-Sarcoglycan Gene by Gulden Diniz, Hulya Tosun Yildirim, Sarenur Gokben, Gul Serdaroglu, Filiz Hazan, Kanay Yararbas, Ajlan Tukun

“…Immunohistochemistry showed that there was diminished expression of alpha- and gamma-sarcoglycans. DNA analysis revealed a novel 7 bp homozygous deletion in exon 3 of the alpha-sarcoglycan gene. …”
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Claudin-11 regulates immunological barrier formation and spermatogonial proliferation through stem cell factor by Taichi Sugawara, Kayoko Sonoda, Nattapran Chompusri, Kazuhiro Noguchi, Seiji Okada, Mikio Furuse, Tomohiko Wakayama

“…Abstract Tight junctions (TJs) between adjacent Sertoli cells are believed to form immunological barriers that protect spermatogenic cells expressing autoantigens from autoimmune responses. However, there is no direct evidence that Sertoli cell TJs (SCTJs) do indeed form immunological barriers. …”
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Identifying effective immune biomarkers in alopecia areata diagnosis based on machine learning methods by Qingde Zhou, Lan Lan, Wei Wang, Xinchang Xu

“…Methods In this study, differential gene expression analysis, immune status assessment, weighted correlation network analysis (WGCNA), and functional enrichment analysis were performed to identify shared genes associated with both immunological response and AA. …”
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Diplomatic History of the Great Patriotic War and the New World Order by A. Y. Borisov

“…It was largely due to the US desire to realize their material advantages to the detriment of the Soviet Union after the war and build a system that would be a one-sided expression of the interests of Washington. Americans, especially after the death of President Roosevelt, and during his successor Truman understood international cooperation as an assertion of its global leadership while ignoring the interests of the Soviet Union, which bore the brunt of the war.…”
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Involvement of Nitric Oxide in a Rat Model of Carrageenin-Induced Pleurisy by Masahiro Iwata, Shigeyuki Suzuki, Yuji Asai, Takayuki Inoue, Kenji Takagi

“…L-arginine and NOC-18 reversed the proinflammatory effects of NO synthase inhibitors, perhaps by reducing the expression of adhesion molecules on endothelial cells. …”
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Plasma membrane and nuclear phosphatidylinositol 4,5-bisphosphate signalling in cancer by Agnieszka Chytła, Stephanie Rattay, Baki Akgül, Martin Sztacho

“…Nuclear phosphoinositides, particularly PI(4,5)P2, are essential for regulating transcription factors and chromatin organisation, thereby shaping gene expression patterns. We also explore the role of PI(4,5)P2 and its metabolism in cancer cell invasiveness and metastasis, proposing a model in which the dysregulation of cytosolic and/or nuclear PI(4,5)P2 pool triggers malignant transformation. …”
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Signaling Crosstalk between PPARγ and BMP2 in Mesenchymal Stem Cells by Ichiro Takada, Yoshiko Yogiashi, Shigeaki Kato

“…Although BMP2 did not interfere with PPARγ-mediated adipogenesis, BMP2 increased mRNA expression levels of PPARγ target genes (such as Fabp4 and Nr1h3) when cells were first treated with troglitazone (TRO). …”
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De Vecinos a Ciudadanos. Las estrategias políticas y culturales en el proceso de formación de la ciudadanía en Colombia: 1810 - 1860 by José Wilson Márquez Estrada

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Ruralidades em perspectiva: identidades e trajetória de cortadores de cana em Pernambuco by Jeanne Mariel Brito de Moura Maciel, Rodrigo Constante Martins

“…A partir de uma pesquisa de campo densa realizada entre os anos 2013-2017 - período de maior expressão do movimento de trânsito dos trabalhadores da cana-de-açúcar para SUAPE -, os dados apontaram para uma intensa movimentação nesse tecido social, com alternância entre o emprego em Suape e nos canaviais. …”
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