Comparison of Febuxostat and Allopurinol in the Treatment of Patients with Chronic Kidney Disease Stage 3∼5 with Hyperuricemia by Zhimin Liao, Lei Xu, Bo Wan, Liping Wang, Chengzhi Zhao, Gang Wu, Rui Xie

“…A total of 100 patients with stage 3 to 5 CKD with hyperuricemia in our hospital from July 2018 to December 2019 were selected and divided into the control group (n = 50) and the experimental group (n = 50) according to the random number expression method, the control group on the basis of conventional treatment with allopurinol treatment, the experimental group based on conventional treatment using the febuxostat be treatment. …”
Get full text

Custos colaterais da violência no Brasil: rumo a um direito moldado pela insegurança? by Diego Werneck Arguelhes, Mariana Pargendler

“…Diferentemente das típicas políticas repressivas à violência, que não raro fragilizam direitos individuais de potenciais ofensores em nome de uma política geral de segurança pública, as políticas adaptativas à insegurança expressam um fortalecimento da proteção dos direitos individuais de potenciais vítimas em detrimento de políticas públicas voltadas à promoção de outros valores sociais relevantes. …”
Get full text

The influence of credits and stigmas in volunteering on depression, the modulating effects of volunteer personality and motivation by Juntao Chen, Yifan Zhang, Suhua Zhou, Chenlu Yang, Lianghua Li, Lu Ma, Shuzhen Zhu

“…Furthermore, volunteers driven by understanding and value expression were more susceptible to the adverse effects of stigmatization. …”
Get full text

قرآنی آیات کی روشنی میں معاصر سائنسی حقائق کا تجزیہ by Dr Saddaqat Hussain

“…It surpasses all forms of human expression, demonstrating a profound depth that leaves an impartial observer in awe. …”
Get full text

Nelfinavir Impairs Glycosylation of Herpes Simplex Virus 1 Envelope Proteins and Blocks Virus Maturation by Soren Gantt, Eliora Gachelet, Jacquelyn Carlsson, Serge Barcy, Corey Casper, Michael Lagunoff

“…NFV did not significantly affect the level of expression of late HSV-1 gene products. Normal numbers of viral particles appeared to be produced in NFV-treated cells by electron microscopy but remain within the cytoplasm more often than controls. …”
Get full text

Development of a multi-epitope chimeric vaccine in silico against Babesia bovis, Theileria annulata, and Anaplasma marginale using computational biology tools and reverse vaccinolo... by Amam Zonaed Siddiki, Sabreena Alam, Farhan Fuad Bin Hossen, Md Abdul Alim

“…The best-designed chimeric vaccine construct was then reverse transcribed and adapted for the host E. coli K12 strain which was later inserted into the pET28a (+) vector for the cloning and expression of the vaccine. The study could be a good initiative for the development of an effective chimeric vaccine against bovine parasites.…”
Get full text

Samorządy dużych polskich miast wobec recentralizacji – postawy i ich uwarunkowania. Studium okresu 2015–2023 by Wirginia Aksztejn, Łukasz Mikuła, Marta Lackowska

“…Referring to the developed typology of these reactions, we attempt to measure the intensity of contestation on the part of cities and determine the variables that build the potential for expressing such contestation. As measures of contestation, we use three variables: the city mayor’s participation in the Self-Government Movement “Yes! …”
Get full text

Automatic Player Face Detection and Recognition for Players in Cricket Games by Mahmood Ul Haq, Muhammad Athar Javed Sethi, Sadique Ahmad, Mohammed A. ELAffendi, Muhammad Asim

“…The system is trained on a large dataset of cricket game footage and achieves high accuracy in detecting and recognizing players’ faces even with several conditions such as occlusion, non-uniform illumination, expression and pose variation. The system has the potential to enhance the viewing experience of cricket games by providing real-time player identification and statistics. …”
Get full text

EZH2 Regulates Lipopolysaccharide-Induced Periodontal Ligament Stem Cell Proliferation and Osteogenesis through TLR4/MyD88/NF-κB Pathway by Pengcheng Wang, Huan Tian, Zheng Zhang, Zuomin Wang

“…LPS stimulation significantly promoted EZH2 and H3K27me3 expression in primary human periodontal ligament stem cells (PDLSCs). …”
Get full text

Targeting Herpetic Keratitis by Gene Therapy by Hossein Mostafa Elbadawy, Marine Gailledrat, Carole Desseaux, Diego Ponzin, Stefano Ferrari

“…Whereas the correction of inherited diseases was the initial goal of the field of gene therapy, here we discuss transgene expression, gene replacement, silencing, or clipping. …”
Get full text

Knowledge Visualization Centers and University Infographics: International and Domestic Experience by A. V. Makulin, M. I. Korzina

“…This is possible due to the advantages that the graphic language provides along with all other ways of expressing and formalizing knowledge. The potentials of infographics for the university environment provide an opportunity to visually operate with vast volumes of knowledge, to search for new interdisciplinary nexus-points and heuristic intersections in the network structure of university science. …”
Get full text

Caffeic Acid Phenethyl Ester Protects Neurons Against Oxidative Stress and Neurodegeneration During Traumatic Brain Injury by Nurul Sulimai, Jason Brown, David Lominadze

“…Earlier we found that extravasated Fg induced an increased expression of neuronal nuclear factor kappa B (NF-κB) p65. …”
Get full text

Structural Analysis of Recombinant Human Preproinsulins by Structure Prediction, Molecular Dynamics, and Protein-Protein Docking by Sung Hun Jung, Chang-Kyu Kim, Gunhee Lee, Jonghwan Yoon, Minho Lee

“…The current system of insulin production is based on recombinant DNA technology, and the expression vector is composed of a preproinsulin sequence that is a fused form of an artificial leader peptide and the native proinsulin. …”
Get full text

Anti-Inflammatory and Antimicrobial Actions of Vitamin D in Combating TB/HIV by Anna K. Coussens, Adrian R. Martineau, Robert J. Wilkinson

“…Conversely, vitamin D can act to inhibit expression and secretion of a broad range of inflammatory mediators and matrix degrading enzymes driving immunopathology during active TB and antiretroviral- (ARV-) mediated immune reconstitution inflammatory syndrome (IRIS). …”
Get full text

Multiple programmed cell death patterns predict the prognosis and drug sensitivity in gastric cancer by Qiying Song, Shihe Liu, Di Wu, Aizhen Cai

“…Immune cell infiltration, immune checkpoint expression, Tumor Immune Dysfunction and Exclusion (TIDE) algorithm and drug sensitivity analysis were used to explore immunotherapy response. …”
Get full text

Enhancing Qualitative Research: The Use of Design Probes and Cooking Sessions Deepens the Understanding of 9- to 11-Year-Old Children’s Food Perceptions by Lotte Pater, Elizabeth H. Zandstra, Vincenzo Fogliano, Bea L. P. A. Steenbekkers

“…These new child-centered qualitative participatory research methods enable to perform the intervention in a natural and real-life context, favouring the expression of thoughts about the research topic. The findings provide evidence that participatory methods should be combined with traditional methods, such as one-to-one interviews, to get richer and more detailed insights into children’s food perceptions in real-world contexts.…”
Get full text

Oral English Auxiliary Teaching System Based on Deep Learning by Chenhui Qu, Yuanbo Li

“…In addition, we should try to solve problems with English logical thinking, which can train our critical thinking and oral expression ability, enhance our self-confidence, and improve our sense of self-efficacy. …”
Get full text

The Mechanisms of Systemic Inflammatory and Immunosuppressive Acute-on-Chronic Liver Failure and Application Prospect of Single-Cell Sequencing by Kai Kou, Xiaodong Sun, Guangyao Tian, Yao Zhi, Zhongqi Fan, Guoyue Lv

“…Finally, we also describe the transcriptomics in HBV-ACLF and the recent progress of single-cell RNA sequencing as well as its potential application in the study of ACLF in the future, in order to gain a deeper understanding of ACLF in terms of single-cell gene expression.…”
Get full text

Genetics and Molecular Biology of Epstein-Barr Virus-Encoded BART MicroRNA: A Paradigm for Viral Modulation of Host Immune Response Genes and Genome Stability by David H. Dreyfus

“…In this review, the author summarizes evidence that recently discovered noncoding RNAs termed microRNA encoded by Epstein-Barr virus BARF (BamHI A right frame) termed BART (BamHI A right transcripts) are modulators of human immune response genes and genome stability in infected and bystander cells. BART expression is apparently regulated by complex feedback loops with the host immune response regulatory NF-κB transcription factors. …”
Get full text

Role of ginsenoside Rg1 as a PPAR-γ activator in protecting against manganese-induced hepatotoxicity: Insights into the TLR4/MyD88/MAPK signaling pathway by Mengjing Zhao, Min Zhang, Shoudong Ni

“…Importantly, as a PPAR-γ activator, Rg1 upregulates PPAR-γ expression, subsequently inhibiting TLR4/MyD88/MAPK pathway. …”
Get full text