The impaired response of nasal epithelial cells to microplastic stimulation in asthma and COPD by Magdalena Paplińska-Goryca, Paulina Misiukiewicz-Stępień, Monika Wróbel, Katarzyna Mycroft-Rzeszotarska, Dorota Adamska, Julia Rachowka, Milena Królikowska, Krzysztof Goryca, Rafał Krenke

“…We identified 8 differentially expressed genes (DEGs) in controls, 309 DEGs in asthma (including ANKRD36C, BCL2L15, FCGBP, and IL-19), and 22 DEGs in COPD (e.g., BCL2L15, IL-19, CAPN14, PGBD5, PTPRH), particularly in epithelial/moMφ co-cultures. …”
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Building Academic Integrity: Evaluating the Effectiveness of a New Framework to Address and Prevent Contract Cheating by Deepani B. Guruge, Rajan Kadel, Samar Shailendra, Aakanksha Sharma

“…Survey results reveal a broad consensus among respondents, who expressed strong confidence in the clarity and effectiveness of the framework and its monitoring procedures. …”
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Practical Aspects of Clinical Manifestations, Pathogenesis and Therapy of Alcoholic Liver Disease and Non-alcoholic Fatty Liver Disease: Expert Opinion by V. V. Tsukanov, M. F. Osipenko, E. V. Beloborodova, M. A. Livzan, I. B. Khlynov, S. A. Alekseenko, Yu. P. Sivolap, J. L. Tonkikh, A. V. Vasyutin

“…In the treatment of NAFLD, diet and lifestyle modification, weight loss, the use of insulin sensitizers, vitamin E, statins (in the presence of hyperlipidemia) and drugs with metabolic activity are effective.Currently, a point of view is being actively expressed about the synergism of the action of alcohol and the metabolic syndrome on the development of fibrosis, cirrhosis, and hepatocellular carcinoma. …”
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Molecular characterization of mixed-histology endometrial carcinoma provides prognostic and therapeutic value over morphologic findings by Paulina J. Haight, Ashwini Esnakula, Courtney J. Riedinger, Adrian A. Suarez, Jessica Gillespie, Ashley Patton, Alexis Chassen, David E. Cohn, Casey M. Cosgrove

“…Transcriptional analysis demonstrated 93 differentially expressed genes between p53abnl and NSMP tumors, including many associated with the innate immune response and DNA damage repair. …”
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Retinal assessment in 143 patients with white matter lesions: the potential of OCTA as an evaluation tool by Dong Zhang, Xueying Jiang, Yan Zhang, Jingcui Qin

“…Qualitative data are expressed as percentages.ResultsAs Fazekas grades increased, ILM-IPL thickness (OR = 3.267, OR = 8.436), vessel density in the parafoveal region of the macula, retinal vessel densities (OR = 2.058, OR = 2.363), and RNFL thickness significantly reduced (p < 0.05). …”
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Peroxisome Proliferator-Activated Receptor γ Regulates Lipid Metabolism in Sheep Trophoblast Cells through mTOR Pathway-Mediated Autophagy by Kexing Hao, Jing Wang, Hengbin Yu, Lei Chen, Weibin Zeng, Zhengrong Wang, Guangdong Hu

“…Peroxisome proliferator-activated receptor gamma (PPARγ) is a key nuclear receptor transcription factor that is highly expressed in trophoblastic cells during embryonic attachment and is accompanied by rapid cell proliferation and increased lipid accumulation. …”
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Depression in Patients Diagnosed with Type 2 Diabetes Mellitus by Dinorah Janet Torres Lugo, Iván Castillo Ledo, Iriam Rojas Díaz, Antonio Masot Rangel, Silvia Janet Masot Torres, Pedro González López

“…The analysis and processing of the information was done using the statistical package SPSS version 15 for Windows, the results were expressed in numbers and percentages. <br /><strong>Results:</strong> predominance of the female sex in 58.3 %, the most represented age group is that of 48-57 (50 %). …”
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Effects of Soil Properties on Pb, Cd, and Cu Contents in Tobacco Leaves of Longyan, China, and Their Prediction Models by Wei Xi, YuanYe Ping, HaiYang Cai, Qian Tan, Chaoyang Liu, Junru Shen, YaWen Zhang

“…The prediction models of lead, cadmium, and copper in tobacco leaves can be expressed by the regression equation corresponding to each heavy metal as follows: YPb=2.33−0.005∗ XK+0.007∗XN −0.271∗XpH+0.065∗XPb (R2 = 0.787), YCd=1.55+0.012∗XOM−0.014∗XCu+34.6∗XCd (R2 = 0.891), and YCu=4.64−0.029∗XP−0.007∗XK+0.245∗XCu (R2 = 0.724), respectively. …”
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HPRS: hierarchical potential-based reward shaping from task specifications by Luigi Berducci, Edgar A. Aguilar, Dejan Ničković, Radu Grosu

“…Consequently, this signal should faithfully reflect the designer’s intentions, which are often expressed as a collection of high-level requirements. …”
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Prehospital video triage of suspected stroke patients in Greater Manchester: pilot project report by Christopher Ashton, Adrian R Parry-Jones, Lisa Brunton, Ibrahim Alghamdi, David A Jenkins

“…However, some reported delays as a result. Clinicians expressed mixed opinions regarding PHVT’s utility. …”
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Effectiveness of Ascophyllum nodosum and Fucus vesiculosus on Metabolic Syndrome Components: A Real-World, Observational Study by Antonio Nicolucci, Maria Chiara Rossi, Massimiliano Petrelli

“…General linear models for repeated measures were applied to assess changes in the parameters of interest during the follow-up. Results are expressed as estimated marginal means with their 95% confidence interval. …”
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From fragmented to integrated healthcare managing hypertension post-stroke: a qualitative study by Hala F. Azhari, Jonathan Hewitt, Martin O'Neill, Alexander Smith, Terence Quinn, Jesse Dawson

“…Data were analyzed thematically to identify barriers and facilitators in hypertension management post-stroke.ResultsKey findings identified four major themes: the need for improved cooperation among multidisciplinary teams, knowledge gaps in stroke survivors regarding hypertension's role in stroke risk, the complexities of polypharmacy, and the potential benefits of ABPM for individualized care. Stroke survivors expressed a reliance on clinicians for hypertension management, while healthcare professionals emphasized the importance of empowering patients through education and self-management. …”
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Pediatric Intensive Care Provider Attitudes About Children with Medical Complexity and Neurologic Impairment: A Qualitative Study by Elizabeth J. Bleed, Leonardo Barrera, Mickayla Jones, Seema K. Shah, Megan Crowley-Matoka, Carolyn C. Foster

“…Rigor was assured by using two coders. (4) Results: Four main themes were identified: (i) providers view CMC with NI as a distinct population of growing importance; (ii) CMC with NI have care needs that challenge traditional perceptions of PICU practice; (iii) PICU providers expressed ambivalence towards caring for CMC with NI; and (iv) some PICU providers have developed adaptive strategies. (5) Conclusions: This population challenges the typical notion of what pediatric critical care represents. …”
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Nutrient inputs shape ecosystem functioning gradients along the pristine, upper Neretva River, Bosnia and Herzegovina by Rubén Del Campo, Barbara Jechsmayr, Veronika Settles, Melanie Ströder, Gabriel Singer

“…While organic matter decomposition was highest in headwaters due to the input of nutrients from riparian vegetation, biofilm enzymatic activity expressed highest values at middle sections due to groundwater inputs of NH4+-N. …”
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Assessment of ABCDE approach knowledge among residents and interns in multiple Egyptian hospitals, a cross-sectional study by Mohamed Saad Rakab, Ahmed B. Zaid, Malak Abbas Hamadein, Salma Abbas Hamadein, Mahmoud Abd Elgawad Ashour, Alaa Samir El-Shamia, Dina Ayman Mostafa, Rahma Mogahed Rateb, Marwa Abdelrahman Elashry, Mennat-Allah Mostafa El-Badawy, Rehab Shaheen Bahram Shaheen

“…Encouragingly, 91.2% expressed willingness for life support training. Statistical analyses unveiled significant associations between knowledge scores and both medical practice settings and sources of ABCDE knowledge. …”
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Geodetic data inversion to estimate a strain-rate field by introducing sparse modeling by Yohei Nozue, Yukitoshi Fukahata

“…Specifically, we impose a sparsity constraint as well as the smoothness constraint on strain rates as prior information, which are expressed by the L1-norm and the L2-norm of the second-order derivative of the velocity field, respectively. …”
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Differential Proliferative Characteristics of Alveolar Fibroblasts in Interstitial Lung Diseases: Regulative Role of IL-1 and PGE2 by Elizabeth Fireman, Shlomo Ben Efraim, Joel Greif, Hava Peretz, Shmuel Kivity, Marcel Topilsky, Yosef Rodrig, A. Yellin, Ron N. Apte

“…Steady levels of IL-1α and βmRNA were expressed in unstimulated and stimulated cultures. …”
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Exploring the efficacy of writing comics as a tool for enhancing EFL writing skills of undergraduate Ecuadorian polytechnic students by Felix Estrella

“…Findings – From the descriptive and T-test results and the interview answers, it is concluded that students have a favorable view of the effectiveness of using comics to improve their writing skills. They also expressed their engagement and motivation to work with comics. …”
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Impact of Seasonal Variations on Semen Parameters: A Retrospective Analysis of Data from Subjects Attending a Tertiary Care Fertility Centre by Anitha Malathi, Ramesh P. Iyer, Reji Mohan, Sheila Balakrishnan

“…Statistical Analysis Used: Data were analysed using SPSS 23 and variables expressed as mean and standard deviation. Changes in mean values over years and over seasons were evaluated using F-test. …”
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Subcutaneous Adipose Tissue from Obese and Lean Adults Does Not Release Hepcidin In Vivo by Lisa Tussing-Humphreys, Keith N. Frayn, Steven R. Smith, Mark Westerman, A. Louise Dennis, Elizabeta Nemeth, Jessica Thomson, Cenk Pusatcioglu

“…Hepcidin is the main regulator of systemic iron homeostasis and is primarily produced by the liver but is also expressed, at the mRNA-level, in periphery tissues including the subcutaneous and visceral adipose tissue. …”
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