ROLE OF THE MODULATORY MEDIATOR SEROTONIN IN THE INDUCTION OF EPIGENETIC PROCESSES DURING LONG TERM MEMORY FORMATION IN HELIX by L. N. Grinkevich, O. V. Vorobiova

“…They include posttraslational histone modifications, which lead to chromatin remodeling and thereby influences gene expression involved in learning. Mollusks are a popular model in neurobiology, because they have relatively simple CNSs with giant neurons. …”
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Functions and applications of RNA interference and small regulatory RNAs by Feng Xuezhu, Guang Shouhong

“…This process involves Argonaute/small RNA (AGO/sRNA) complexes that target transcripts via sequence complementarity and modulate gene expression and epigenetic modifications. RNAi is a highly conserved gene regulatory phenomenon that recognizes self- and non-self nucleic acids, thereby defending against invasive sequences. …”
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Is PPAR𝛾 a Prospective Player in HIV-1-Associated Bone Disease? by Eoin J. Cotter, Patrick W. Mallon, Peter P. Doran

“…Alterations in PPAR𝛾 expression have been implicated as a factor in the mechanism of HIV-1-associated lipodystrophy. …”
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Filipino attitude and perception on Subscriber Identity Module (SIM) Card Registration Act by Aera L. Diaz, Romano M. Balbacal

“…Participants’ attitudes toward the Act were shaped by their experiences with mobile phone technology and privacy concerns, with older respondents expressing heightened sensitivity to data privacy. These insights underscore the need for more robust security measures in the registration process to enhance public trust. …”
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TRIM21-mediated PRMT1 degradation attenuates colorectal cancer malignant progression by Menghan Cao, Zhiying Shao, Xingyou Qian, Miaolei Chen, Chuyin Deng, Xintian Chen, Tingting Tang, Kaixu Zhang, Sufang Chu, Junnian Zheng, Jin Bai, Zhongwei Li

“…In this study, we found that TRIM21 expression is reduced in primary CRC tissues. Low levels of TRIM21 in CRC are associated with unfavorable clinicopathological characteristics and shorter survival. …”
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Research on Arch Model and Numerical Simulation of Critical Water and Sand Inrush in Coal Mine near Unconsolidated Layers by Guibin Zhang, Wenquan Zhang, Hailong Wang, Siwen Cao, Yuliang Wu, Zaiyong Wang

“…The paper also proposed and established three critical arching mechanics models (interlocking arch, bonded arch, and transition arch), deduced the mathematical expression of interlocking arch and transition arch, and obtained the critical instability conditions of the arch and its influencing factors. …”
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Promoting Articular Cartilage Regeneration through Microenvironmental Regulation by Kai Liu, Bingjun Zhang, Xiaoling Zhang

“…We find that regulating the opening of mechanosensitive ion channels, regulating the expression of HIF-1, delivering growth factors, and clearing senescent cells can promote the formation of articular cartilage regeneration microenvironment. …”
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S-Glutathionylation of Protein Disulfide Isomerase Regulates Estrogen Receptor α Stability and Function by Ying Xiong, Yefim Manevich, Kenneth D. Tew, Danyelle M. Townsend

“…Such drug treatment also reverses estradiol-induced upregulation of c-Myc, cyclinD1, and P21Cip, gene products involved in cell proliferation. Expression of an S-glutathionylation refractory PDI mutant diminishes the toxic effects of PABA/NO. …”
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Collagen peptide protects Saccharomyces cerevisiae from furfural stress for enhancing bioethanol synthesis by Ming Yang, Xia Li, Bo Wang, Xian Liu, Bo Zhang, Xue-Pin Liao

“…Transcriptome analysis showed CP can improve the expression of genes (FBA1, PDC1, PDC6, and ENO1) associated with glycolysis to promote sugar utilization, and enhance ethanol biosynthesis under furfural stress, which were further verified by quantitative real-time PCR. …”
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The Interaction of Src Kinase with β3 Integrin Tails: A Potential Therapeutic Target in Thrombosis and Cancer by Stephan Huveneers, Erik H. J. Danen

“…The same integrin β3-c-Src interaction not only drives platelet aggregation, but it also promotes the oncogenic potential of c-Src and drives tumor growth by αvβ3-expressing tumor cells, which may explain why increased activity of c-Src and elevated levels of integrin αvβ3 are often found in the same tumor types. …”
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Pensar desde a América Latina em diálogo com a organização das lutas sociais descoloniais: Explorando possibilidades by Maria Ceci Araújo Misoczky, Guilherme Dornelas Camara

“…Por fim, destaca a importância de um conhecimento fundado em uma ética crítica que contribua para tornar visíveis processos organizacionais que confrontam as múltiplas expressões concretas da colonialidade e que, ao mesmo tempo, seja relevante para as comunidades e coletivos em luta. …”
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Computational design of multi-epitope vaccine against Hepatitis C Virus infection using immunoinformatics techniques. by Sara Zubair, Fahed Parvaiz, Turki Abualait, Khalid Al-Regaiey, Tasneem Anwar, Mahnoor Zafar, Imdad Kaleem, Shahid Bashir

“…The vaccine construct was also subjected to In-Silico cloning which confirmed its expression efficiency in a vector. The findings indicate that the designed multi-epitope vaccine have a great potential for preclinical and clinical research, which is an important step in addressing the problems related to HCV infection.…”
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The Role of Vascular Endothelial Growth Factor in Metastatic Prostate Cancer to the Skeleton by Emma Roberts, Davina A. F. Cossigny, Gerald M. Y. Quan

“…The importance of VEGF in the complex process of prostate cancer dissemination to the skeleton is discussed, including its role in the development of the bone premetastatic niche, metastatic tumour cell recognition of bone, and bone remodeling. The expression of VEGF has also been shown to be upregulated in prostate cancer and is associated with clinical stage, Gleason score, tumour stage, progression, metastasis, and survival. …”
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The Role of Methylation in Chronic Lymphocytic Leukemia and Its Prognostic and Therapeutic Impacts in the Disease: A Systematic Review by Sevastianos Chatzidavid, Christina-Nefeli Kontandreopoulou, Nefeli Giannakopoulou, Panagiotis T. Diamantopoulos, Christos Stafylidis, Marie-Christine Kyrtsonis, Maria Dimou, Panayiotis Panayiotidis, Nora-Athina Viniou

“…The following is a review focusing on the present knowledge about single gene/gene promoter methylation or mRNA expression in CLL cases as well as records of older data that have been published in past papers.…”
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Simplified Analysis of Thermal Cracks in Low-Heat Portland Cement Concrete by Longlong Liu, Shangchuan Zhao, Jianda Xin, Zhenhong Wang

“…Although the FA content decreases the hydration heat and the strength at an early age, there are few influences on the relational expression between compressive strength and tensile strength. …”
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HCNetlas: A reference database of human cell type-specific gene networks to aid disease genetic analyses. by Jiwon Yu, Junha Cha, Geon Koh, Insuk Lee

“…Often, a gene impact on disease through its altered network within specific cell types, rather than mere changes in expression levels. To explore the cell type-specific roles of disease genes, we developed HCNetlas (human cell network atlas), a resource cataloging cell type-specific gene networks (CGNs) for various healthy tissue cells. …”
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Suppression of Human Tenon Fibroblast Cell Proliferation by Lentivirus-Mediated VEGF Small Hairpin RNA by Zhongqiu Li, Wen Hua, Xuedong Li, Wei Wang

“…Subsequently, VEGF mRNA and protein expression were analyzed using quantitative RT-PCR and western blotting, respectively, and the effects of VEGF knockdown were analyzed. …”
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An Integrated Approach of Video Game Therapy^®: A Case Study by Maura Crepaldi, Francesco Bocci, Marcello Sarini, Andrea Greco

“…Starting from these premises, the study shows promising results, presenting a single case of a boy with social isolation problems and relational difficulties, in which significant changes were highlighted in the perception, expression, and management of emotions, as well as in metacognition and self-efficacy.…”
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Etiopatogenia de la microangiopatía diabética. Consideraciones bioquímicas y moleculares by Milagros Lisset León Regal, Lázaro Hermes González Otero, Zoe Alina González Otero, José Omar de Armas García, Alexis Urquiza Hurtado, Gerardo Rodríguez Caña

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REPRESENTATION OF IRONY IN WHATSAPP GROUP CHAT by Anna Riana Suryanti Tambunan, Fauziah Khairani Lubis, Winda Setia Sari, Widya Andayani, Moh Hilman Fikri

“…Moreover, the result disclosed that touches of sarcasm were the favorable choice of irony to express the participants’ feelings. Sarcasm was detected by using uppercase characters, exclamation marks, and teasing words. …”
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