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10701
Assessment of SREBP Activation Using a Microsomal Vesicle Budding Assay
Published 2024-12-01“…To be active, SREBPs are translocated to the Golgi where the transcriptionally active N-terminus is cleaved and released to the nucleus to regulate gene expression. Nuclear SREBP levels can be determined by immunoblot analysis; however, this method can only determine the steady-state levels of nuclear SREBPs and does not capture the actual status of activation. …”
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10702
The Unified Strength Theory for Plastic Limit Load Analysis of Vertical Shaft Lining
Published 2018-01-01“…In this paper, the analytical stress expression and formulas for computing plastic limit load have been deduced based on the unified strength theory. …”
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10703
The Notion of “Philosophy as a Way of Life”: Ambiguities and Open Questions
Published 2024-12-01“…What exactly does this expression contain? What does it entail? To what extent is it clear and univocal? …”
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10704
Fatherhood among adolescents in conflict with the law: A family systemic approach
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10705
An Analytical, Numerical, and Experimental Investigation on Transverse Vibrations of a Finite Locally Resonant Beam
Published 2022-01-01“…The analytical solution of the coupling vibration equations was derived based on the modal superposition method, and the analytical expression of average velocity response and vibration transmissibility were given. …”
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10706
Selection of adaptive strategies in child development through modeling of the Neutrosophic VIKOR method
Published 2024-11-01“…The first promoted autonomy, creativity, and social skills, while the second enhanced coordination, memory, and emotional expression. In conclusion, both strategies, when adapted to individual needs, have demonstrated a positive impact in school and family environments, providing a solid foundation for future educational policies focused on child well-being.…”
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10707
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10708
Defensive Driving: Directing HIV-1 Vaccine-Induced Humoral Immunity to the Mucosa with Chemokine Adjuvants
Published 2018-01-01“…This control is mediated by chemoattractant chemokines or cytokines which recruit immune cells expressing the cognate receptors and adhesion molecules. …”
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10709
Alternative 3′ UTR polyadenylation is disrupted in the rNLS8 mouse model of ALS/FTLD
Published 2025-01-01“…Here, we identify significant disruptions to 3` UTR polyadenylation in the ALS/FTLD-TDP mouse model rNLS8 that correlate with changes in gene expression and protein levels through the re-analysis of published RNA sequencing and proteomic data. …”
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10710
Significados e Modelagem na Atividade Algébrica
Published 2003-01-01“…Dessa forma, ao invés de assumir que os indivíduos suspendem o significado de expressões algébricas no processo de modelagem, este texto discute e exemplifica maneiras pelas quais é possível monitorar e investigar precisamente como alunos de matemática do ensino fundamental são capazes de construir tais relações nesse processo. …”
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10711
Scattering and Bound States of a Spin-1/2 Neutral Particle in the Cosmic String Spacetime
Published 2017-01-01“…Examining the poles of the S-matrix we obtain an expression for the bound states. The presence of bound states for this system has not been discussed before in the literature.…”
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10712
Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno-Histochemistry and Tv Image Cytometry
Published 2000-01-01“…We compared the cell proliferation activity of H. pylori positive and negative gastric epithelial biopsies in chronic gastritis with and without intestinal metaplasia (IM) and gastric cancer by the expression of proliferation cell nuclear antigen (PCNA) and Tv image cytometry, and assessed the effect of H. pylori eradication on the cell proliferation rate in the gastric epithelium.…”
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10713
Molecular Mechanisms Underlying Hypothermia-Induced Neuroprotection
Published 2011-01-01“…In this paper, we addressed this issue by utilizing comprehensive gene and protein expression analyses of ischemic rat brains. To predict precise target molecules, we took advantage of the therapeutic time window and duration of hypothermia necessary to exert neuroprotective effects. …”
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10714
Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces
Published 2015-01-01“…In the periodontal ligament and alveolar bone, the mechanically induced tensile strains upregulate the expression of osteogenic genes resulting in bone formation, while mechanically induced compressive strains mediate predominantly catabolic tissue changes and bone resorption. …”
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10715
Research on Customer Requirement-Driven Individualized Product Module Division and Configuration Based on Community Structure
Published 2022-01-01“…Firstly, the product properties are decomposed, and a standardized CR expression template is established to enable the mapping of CR information to product properties change information. …”
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10716
Les stratégies spatiales de la population haïtienne à Miami
Published 2008-02-01“…Resulting from an aggregation/segregation dynamics, Haitian spatial concentration in Miami found expression in particular settlement locations, where processes of territorialization have taken place. …”
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10717
Le « devoir de mémoire », fabrique du postcolonial ? Retour sur la genèse de la « loi Taubira »
Published 2012-01-01“…L’expression « devoir de mémoire » s’est imposée dans le discours politique français au cours des années 1990 à la faveur de l’écriture d’un « roman postnational » comportant deux nouveaux impératifs pour l’État : commémorer des morts à cause de la France (Vichy), et reconnaître officiellement une communauté mémorielle (la communauté juive) victime d’un génocide. …”
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10718
miR-149 Inhibits Non-Small-Cell Lung Cancer Cells EMT by Targeting FOXM1
Published 2013-01-01“…Here we found that the expression of miR-149, downregulated in lung cancer, was inversely correlated with invasive capability and the EMT phenotype of NSCLC cells. miR-149 inhibited EMT in NSCLC cells. …”
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10719
Renal Tubular Cells from Hibernating Squirrels are Protected against Cisplatin Induced Apoptosis
Published 2020-01-01“…To determine whether XIAP and Akt1 are necessary for RTEC protection against cisplatin induced apoptotic cell death, gene expression of Akt1 or XIAP was silenced in squirrel RTECs. …”
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10720
Silent enemy of the hand: The Viking disease
Published 2024-01-01“…It is more common in Caucasian men, and heredity, which shows variable expression, plays a vital role in its aetiology. The etiopathogenesis of DK is still unclear and includes the formation of collagen nodules, which progress into fibrous bands between the dermis and fascia at pressure points. …”
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