The Role of p38 MAPK in the Aetiopathogenesis of Psoriasis and Psoriatic Arthritis by Athanasios Mavropoulos, Eirini I. Rigopoulou, Christos Liaskos, Dimitrios P. Bogdanos, Lazaros I. Sakkas

“…Signaling pathway defects have long been hypothesized to participate in the pathology of psoriasis, yet their implication in the altered psoriatic gene expression still remains unclear. Emerging data suggest a potential pathogenic role for mitogen activated protein kinases p38 (p38 MAPK) extracellular signal-regulated kinase 1/2 (ERK1/2), and c-Jun N-terminal kinase (JNK) in the development of psoriasis. …”
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A Prediction Model for Concrete Cracks due to Chloride-Induced Corrosion by Jiao Wang, Ling Li, X. G. Zhang, Yangang Zhao

“…The analytical model proposed in this paper has an accuracy of 92%, indicating that our expression for crack spacing can effectively predict the location of cracks.…”
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The Potential Importance of MicroRNAs as Novel Indicators How to Manage Patients with Juvenile Idiopathic Arthritis More Effectively by Krzysztof Orczyk, Elzbieta Smolewska

“…Small, noncoding sequences of ribonucleic acid called microRNAs (miRNAs, miR) are functioning as posttranscriptional regulators of gene expression. As they draw increasing attention of rheumatologists, there is a growing body of evidence concerning specific molecules that may affect the long-term care of patients with inflammatory arthritides. …”
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Current status of recombinant duck enteritis virus vector vaccine research by Wen-Feng Jia, An-Ping Wang, Zhi Wu, Xin-Nuo Lei, Yu-Ting Cheng, Shan-Yuan Zhu

“…It is suitable as a live virus vector for inserting and expressing antigenic genes from other pathogens to develop multivalent vaccines. …”
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The Role of the Arts in the Classroom: Does Integration of the Arts Promote Social Relationships in the Classroom? by Julia Lauss, Christoph Helm

“…Integrating the arts into classrooms fosters these relationships by promoting creative expression and social skills such as empathy, mutual support, and teamwork. …”
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Territorio mutual: una lectura del proceso de trasformación territorial desde la alteridad de la comunidad LGBTI víctima del desplazamiento forzado en el Quindío by Carlos Alberto Castaño-Aguirre

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Estados Unidos: unilateralismo y política exterior. Notas para un debate by Dino Amador Allende González

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Melatonin and its therapeutic prospects in gastroenterology by A. A. Svistunov, Mikhail A. Osadchuk, A. M. Osadchuk

“…At progression of organic disease, development of malignant neoplasms, hypoplasia of melatonin-producing cells was found, melatonin expression is decreased that indicates exhaustion of adaptive mechanisms. …”
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Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report by Zamin Adigozalli, Rasim Khalilov, Steffen Seyfried

“…Histopathological examination confirmed a PDGFRA mutation, loss of c-kit and DOG 1 expression, and a high mitotic rate, categorizing the tumor as high risk. …”
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Analysis of amperometric biosensor utilizing synergistic substrates conversion: Akbari-Ganji's method by K. P. V. Preethi, H. Alotaibi, J. Visuvasam

“…The Akbari-Ganji's method (AGM) was used to calculate the semi-analytical expressions for species concentration and normalized current. …”
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Nobiletin Protects Endothelial Cell Function via Upregulation of eNOS/ET-1 and Antioxidant Status-Related Genes under Nonstimulated and Inflammatory Conditions by Lu Li, Biyun Zhang, Ludovica De Pieri, Yue Wu, Karen Birch, Christine Boesch

“…Our aim was to investigate the potential of nobiletin to enhance endothelial cell functionality under nonstimulated and inflammatory conditions. To this end, gene expression relevant to nitric oxide (NO) production, endothelin 1 (ET-1), and antioxidant status in human endothelial cells EA.hy926 was determined using real-time PCR. …”
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Intratumor heterogeneity in KRAS signaling shapes treatment resistance by Oleksi Petrenko, Varvara Kirillov, Stephen D'Amico, Nancy C. Reich

“…We identify distinct cell populations that vary in their gene expression patterns pertaining to the predicted level of KRAS signaling activity, cell growth, and differentiation commitment within each tumor. …”
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JT gravity, KdV equations and macroscopic loop operators by Kazumi Okuyama, Kazuhiro Sakai

“…We show that the partition function of JT gravity is written as the expectation value of a macroscopic loop operator in the old matrix model of 2d gravity in the background where infinitely many couplings are turned on in a specific way. Based on this expression we develop a very efficient method of computing the partition function in the genus expansion as well as in the low temperature expansion by making use of the Korteweg-de Vries constraints obeyed by the partition function. …”
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El acto transductivo, una aproximación epistemológica y estética desde la teoría de Gilbert Simondon by KARINA ERIKA ROJAS CALDERÓN

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Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog. by Eric Dessaud, Vanessa Ribes, Nikolaos Balaskas, Lin Lin Yang, Alessandra Pierani, Anna Kicheva, Bennett G Novitch, James Briscoe, Noriaki Sasai

“…Assays of intracellular signal transduction and gene expression indicate that the duration as well as level of signalling is critical for morphogen interpretation. …”
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O serviço social brasileiro frente à desigualdade social e à pauperização by Giselle Ávila Leal de Meirelles

“… O objetivo deste artigo é aprofundar teórica e metodologi- camente a compreensão sobre a desigualdade social e a pauperização (empobrecimento) da classe trabalhadora brasileira, entendidas aqui como expressões universais da questão social no modo de produção capitalista. …”
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Hedgehog signaling directs cell differentiation and plays a critical role in tendon enthesis healing by Fei Fang, Matthew Casserly, Julia Robbins, Stavros Thomopoulos

“…Activation of Hh signaling at the injured mature enthesis promoted fibrocartilage formation, enhanced mineralization, and increased expression of chondrogenic and osteogenic markers, which implies that Hh signaling drives cell differentiation to regenerate the damaged enthesis. …”
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Identification of Bexarotene as a PPARγ Antagonist with HDX by David P. Marciano, Dana S. Kuruvilla, Bruce D. Pascal, Patrick R. Griffin

“…The RXRs form heterodimers with several nuclear receptors (NRs), including peroxisome proliferator-activated receptor gamma (PPARγ), to regulate target gene expression through cooperative recruitment of transcriptional machinery. …”
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Aggressive CD5-Positive Primary Bone Marrow Diffuse Large B-Cell Lymphoma with Leukemic Presentation by Mark G. Evans, Sherif A. Rezk, Lauren C. Pinter-Brown, Xiaohui Zhao

“…It may demonstrate a leukemic presentation, and a proportion of cases have CD5 expression. The prognostic implications of this CD5-positivity remain unknown. …”
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Natural Compounds as Regulators of NLRP3 Inflammasome-Mediated IL-1β Production by József Tőzsér, Szilvia Benkő

“…Its activation requires two signals: one signal “primes” the cells and induces the expression of NLRP3 and pro-IL-1β, while the other signal leads to the assembly and activation of the complex. …”
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