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10521
Matemáticas Divergentes no rio Maracapucu
Published 2024-12-01“…Além de apontar a importância de uma Educação Matemática nas escolas ribeirinhas que respeite as formas do indivíduo matematizar o conhecimento e expressar sua inteligência. …”
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10522
Hepatocyte Turnover in Chronic HCV-Induced Liver Injury and Cirrhosis
Published 2015-01-01“…New insights in HCV-induced hepatocellular injury, differential gene expression, and regenerative pathways have recently revealed a different pattern of progression to irreversible parenchymal liver damage. …”
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10523
Nuclear Receptors in the Pathogenesis and Management of Inflammatory Bowel Disease
Published 2019-01-01“…The protective roles of rifaximin and rifampicin partly depend on promoting pregnane X receptor (PXR) expression. The aims of this review are to discuss the roles of several important NRs, such as PPARγ, PXR, vitamin D receptor (VDR), farnesoid X receptor (FXR), and RAR-related orphan receptor gammat (RORγt), in the pathogenesis of IBD and management strategies based on targeting these receptors.…”
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10524
Peut-on trouver trace de la Loi islamique dans les documents arabes chrétiens de Tolède des XIIe et XIIIe siècles?
Published 2016-12-01“…Yet, over and above the formal issues, it is not easy to find a direct influence of the Islamic law in those diplomas. Even an expression of Arab origin as evident as «marjadraque» [marǧi‘al-darak] it does not necessarily addresses to any Islamic law rule, as that guarantee was already assured in the Visigoths’ law. …”
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10525
3C-BASED METHODS FOR 3D GENOME ORGANIZATION ANALYSIS
Published 2014-12-01“…The 3D organization of an eukaryotic genome plays an important role in nuclear gene expression. Until recently, studies of this organization were limited by light microscopy and electron microscopy methods. …”
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10526
Contrarreformas e Recuo Civilizatório: Um Breve Balanço Do Governo Temer
Published 2019-03-01“…Para tanto, apresentamos as principais medidas para a retomada das taxas de lucro do capital: o desmonte das políticas sociais; o avanço privado sobre os recursos do fundo público, em especial no que tange à dívida pública e à s desonerações tributárias, e a consequente agudização das expressões da “questão social”. No primeiro item, por meio da exposição dos recentes dados da Pnad/IBGE, demonstramos o grave retrocesso à garantia de direitos sociais fundamentais e chamamos atenção para a ruptura com o “pacto social” efetivado na Constituição Federal de 1988. …”
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10527
Competing Endogenous RNA: The Key to Posttranscriptional Regulation
Published 2014-01-01“…These MRE sharing elements form the posttranscriptional ceRNA network to regulate mRNA expression. ceRNAs are widely implicated in many biological processes. …”
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10528
Memory and Recalling in Shelagh Stephenson’s The Memory of Water
Published 2023-03-01“…In addition to the chronological description of memory, how it is evaluated under the effect of historical development as well as the significance of it in the life cycle of human beings is likewise specified in this study. Expressing the thoughts and research of various thinkers and philosophers, this study represents the variable approaches to memory. …”
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10529
The role of laminins in cancer pathobiology: a comprehensive review
Published 2025-01-01“…Understanding the complex roles of LMs in cancer biology, as well as their differential expression patterns in malignancies, could provide new diagnostic tools for predicting disease outcomes and pave the way for innovative therapeutic strategies, such as targeting LM-receptor interactions or modulating ECM dynamics to impede tumor growth and metastasis.…”
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10530
LA SENDA BIOCÉNTRICA: VALORES INTRÍNSECOS, DERECHOS DE LA NATURALEZA Y JUSTICIA ECOLÓGICA
Published 2010-01-01“…Se analizan los aportes sobre los valores intrínsecos en el ambiente, su expresión en posturas biocéntricas y los contrastes con el antropocentrismo propio de la Modernidad. Se consideran sus expresiones concretas en América Latina, especialmente en la nueva Constitución de Ecuador. …”
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10531
Evaluation of Fluorescent Analogs of Deoxycytidine for Monitoring DNA Transitions from Duplex to Functional Structures
Published 2011-01-01“…Topological variants of single-strand DNA (ssDNA) structures, referred to as “functional DNA,” have been detected in regulatory regions of many genes and are thought to affect gene expression. Two fluorescent analogs of deoxycytidine, Pyrrolo-dC (PdC) and 1,3-diaza-2-oxophenoxazine (tC∘), can be incorporated into DNA. …”
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10532
The Role of TOX in the Development of Innate Lymphoid Cells
Published 2015-01-01“…Innate lymphoid cells, classified according to transcription factor expression and cytokine secretion profiles, derive from common lymphoid progenitors in the bone marrow and require Notch signals for their development. …”
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10533
Epigenetic Modifications and Potential New Treatment Targets in Diabetic Retinopathy
Published 2014-01-01“…Indeed, epigenetic changes may lead to stable modification of gene expression, participating in DR pathogenesis. Moreover, increasing evidences suggest that environmental factors such as chronic hyperglycemia are implicated DR progression and may also affect the epigenetic state. …”
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10534
Modulatory effects in circadian-related diseases via the reciprocity of tea polyphenols and intestinal microbiota
Published 2022-05-01“…Phytochemicals such as tea polyphenols (TP) can interact with the intestinal flora and participate in regulating the expression and rhythm of biological clock genes. Circadian rhythm controls a variety of behaviors and physiological processes, and circadian misalignment has been found to be closely related to multiple metabolic diseases. …”
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10535
Rare Case of Spinal Neurosarcoidosis with Concomitant Epidural Lipomatosis
Published 2021-01-01“…Both etiologies are inflammatory in nature and share similar expression of inflammatory factors such as TNF-α and IL-1β. …”
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10536
Microgravity, Stem Cells, and Cancer: A New Hope for Cancer Treatment
Published 2021-01-01“…Microgravity has been shown to have significant effects on cellular proliferation, invasion, apoptosis, migration, and gene expression, specifically in tumor cells, and these effects may also exist in stem and cancer stem cells. …”
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10537
Newly Diagnosed Colonic Adenocarcinoma: The Presenting Sign in a Young Woman with Undiagnosed Crohn’s Disease in the Absence of Primary Sclerosing Cholangitis and a Normal Microsat...
Published 2017-01-01“…Histopathology revealed a moderately differentiated adenocarcinoma extending through the muscularis propria with metastatic lymph nodes and intact mismatch repair proteins by immunohistochemical expression and gene sequencing. The nonneoplastic grossly uninvolved background mucosa showed marked crypt distortion, crypt abscesses, CD-like lymphoid hyperplasia, transmural inflammation, and reactive epithelial atypia. …”
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10538
The Ecosystem of AI-Driven Robotics in Pediatric Neurorehabilitation
Published 2025-02-01“…Moreover, the inclusion of natural language processing and facial expression analysis warrants careful consideration, as it sets the stage for more nuanced interactions between robots and pediatric patients, thereby fostering a therapeutic environment that is both responsive and empathetic. …”
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10539
Comparisons of performances of structural variants detection algorithms in solitary or combination strategy.
Published 2025-01-01“…Structural variants (SVs) have been associated with changes in gene expression, which may contribute to alterations in phenotypes and disease development. …”
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10540
RhoA Regulation of Cardiomyocyte Differentiation
Published 2013-01-01“…To investigate factors that potentially regulate RhoA expression, RhoA gene organisation and promoter activity were analysed. …”
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