Clinical and Pathogenetic Parallels of Nonalcoholic Fatty Liver Disease and Gallstone Disease by Aleksey O. Bueverov

“…These include central and peripheral insulin resistance, changes in the expression of transcription factors (liver X-receptor and farnesoid X-receptor) and the bile acid membrane receptors (TGR5). …”
Get full text

Selective Modulators of PPAR-γ Activity: Molecular Aspects Related to Obesity and Side-Effects by Fang Zhang, Brian E. Lavan, Francine M. Gregoire

“…SPPARγMs bind in distinct manners to the ligand-binding pocket of PPAR-γ, leading to alternative receptor conformations, differential cofactor recruitment/displacement, differential gene expression, and ultimately differential biological responses. …”
Get full text

A Novel Type of Non-coding RNA, nc886, Implicated in Tumor Sensing and Suppression by Yong Sun Lee

“…nc886 (=vtRNA2-1, pre-miR-886, or CBL3) is a newly identified non-coding RNA (ncRNA) that represses the activity of protein kinase R (PKR). nc886 is transcribed by RNA polymerase III (Pol III) and is intriguingly the first case of a Pol III gene whose expression is silenced by CpG DNA hypermethylation in several types of cancer. …”
Get full text

De encuentros y desencuentros entre jóvenes y personas adultas a propósito de salir de la enseñanza secundaria en Chile by Klaudio Duarte\u2013Quapper, Diego Aniñir\u2013Manríquez, Antonia Garcés\u2013Sotomayor

Get full text

« Je ne suis pas un zéro ». Pour une distinction entre absence d’article et article zéro en anglais contemporain by Florent Moncomble

“…Some linguists argue that the expression “absence of article” would be more appropriate, yet do not question the validity of the monolithic approach.In this article, we support the idea that a number of structures involving the absence of a marked determiner are indeed cases where no determination whatsoever occurs. …”
Get full text

Antiviral Activity of Resveratrol against Human and Animal Viruses by Yusuf Abba, Hasliza Hassim, Hazilawati Hamzah, Mohamed Mustapha Noordin

“…Its antioxidant effect is mainly elicited through inhibition of important gene pathways like the NF-κβ pathway, while its antiviral effects are associated with inhibitions of viral replication, protein synthesis, gene expression, and nucleic acid synthesis. Although the beneficial roles of resveratrol in several viral diseases have been well documented, a few adverse effects have been reported as well. …”
Get full text

Long non-coding RNA linc00152 acting as a promising oncogene in cancer progression by Danbi Seo, Dain Kim, Wanyeon Kim

“…In this review, we focus on the oncogenic role of linc00152 in tumorigenesis and provided an overview of recent clinical studies on the effects of linc00152 expression in human cancers.…”
Get full text

Biochemical Analysis of Histone Succinylation by Atsushi Yokoyama, Shogo Katsura, Akira Sugawara

“…Histone PTMs are regarded as some of the most important, as they can directly regulate gene expression through chromatin reorganization. Recently, histone proteins were found to undergo succinylation, adding to other well-known PTMs such as acetylation, methylation, and phosphorylation. …”
Get full text

Extra Fructose in the Growth Medium Fuels Lipogenesis of Adipocytes by Armin Robubi, Klaus R. Huber, Walter Krugluger

“…Cells developed lipid vesicles much earlier with fructose and showed altered kinetics of the expression of mRNAs involved in lipogenesis and hexose uptake. …”
Get full text

Protein Phosphatase 2A: Role in T Cells and Diseases by Suyasha Roy, Lalit Batra

“…Genetic deletion of PP2A in Tregs disrupts Foxp3 expression due to hyperactivation of mTORC1 signaling which impairs the development and immunosuppressive functions of Tregs. …”
Get full text

Desvelado silencio: La voz a ti debida. (El título como indicador catafórico e intertextual) by Joaquín Corencia Cruz

Get full text

An Experimental In Vivo Model to Characterize “Heavy Legs” Symptom in Topical Formulations by Pedro Contreiras Pinto, Luís Monteiro Rodrigues

“…The “Heavy legs” symptom is regarded as an early expression of chronic venous failure, estimated to affect 40% of the population in developing countries. …”
Get full text

Tumor venéreo transmissível canino com resistência quimioterápica e metástase esplênica. Relato de caso by A. P. Duzanski, A. D. Ortiz, H. B. Fêo, M. W. Fonseca, M. M. Flórez, L. T Rodrigues, F. Michelon, N. S. Rocha

“…After the cytological, histological and cytogenetic diagnostic, the primary tumor was still characterized in progression phase and showed low major histocompatibility complex expression MHC (4,4 ± 2% class I e 11 ± 4,1% class II. …”
Get full text

Antioxidant Functions of Nitric Oxide Synthase in a Methicillin Sensitive Staphylococcus aureus by Manisha Vaish, Vineet K. Singh

“…In this study it was determined that under normal growth conditions, expression of SaNOS was highest during early exponential phase of the bacterial growth. …”
Get full text

The issue of the hybrid regime genesis in Venezuela (1999–2013) by G. E. Ludena Lopez

“…According to the author of the article, the peculiarity of the Chavez administration is that not only legal, regulatory and informal instruments aimed at restricting freedom of expression and assembly, hindering the emergence of democratic pluralism, but also repressive measures.…”
Get full text

Alternative Splicing and Its Impact as a Cancer Diagnostic Marker by Yun-Ji Kim, Heui-Soo Kim

“…Most genes are processed by alternative splicing for gene expression, resulting in the complexity of the transcriptome in eukaryotes. …”
Get full text

Violencia estatal y movimientos sociales mapuche: pichikeche violentados, una rebelión incubada by Olga Angélica Vásquez-Palma, Noemí E. Alarcón-Retamal, Claudia A. Torres-Morales, Isamar S. Llanquinao-Sandoval

Get full text

Bipolar Soft Sets: Relations between Them and Ordinary Points and Their Applications by Tareq M. Al-shami

“…These relations are considered as one of the unique characteristics of bipolar soft sets which are somewhat expression of the degrees of membership and nonmembership of an element. …”
Get full text

The Role of Peroxisome Proliferator-Activated Receptors in Colorectal Cancer by Joo-In Park, Jong-Young Kwak

“…Even though many investigators have studied the expression and clinical implications of PPARs in colorectal cancer, there are still many controversies about the role of PPARs in colorectal cancer. …”
Get full text

Crocetin Alleviates Inflammation in MPTP-Induced Parkinson’s Disease Models through Improving Mitochondrial Functions by Na Dong, Zhong Dong, Ying Chen, Xiaosu Gu

“…Both in vivo and in vitro experiments demonstrated that crocetin treatment decreased the expression of inflammatory associated genes and inflammatory cytokines. …”
Get full text