Integrated Bioinformatics Identifies FREM1 as a Diagnostic Gene Signature for Heart Failure by Chenyang Jiang, Weidong Jiang

“…The heart failure microarray datasets and RNA-seq datasets have been downloaded from the public database. Differentially expressed genes (DE genes) are screened out, and then, we analyze their biological functions and pathways. …”
Get full text

Children Who Experience Unintentional Injuries: Their Functional Profiles by Sara Rosenblum, Tal Nardi-Moses, Helly Goez, Naor Demeter

“…Parents of children who had been injured expressed significantly more concerns about their children’s daily behavior than did parents of the control group and reported their children as usually, but not always, independent and responsible. …”
Get full text

Digital Sovereignty in times of AI: between perils of hegemonic agendas and possibilities of alternative approaches by Alexandre Costa-Barbosa, Bianca Herlo, Gesche Joost

“…Nations-states worldwide have developed policies or expressed through speeches the need to safeguard their interests in the digital realm. …”
Get full text

Emotions as Self-Organizational Factors of Anthropogenesis, Noogenesis and Sociogenesis by І. M. Hoian, V. P. Budz

“…At the bodily level, emotions are expressed as biochemical and hormonal reactions. At the spiritual level emotions create the basis for the development of the mind, which originates as emotional consciousness. …”
Get full text

Gene by Sex Interaction for Measures of Obesity in the Framingham Heart Study by Ashlee M. Benjamin, Sunil Suchindran, Kaela Pearce, Jennifer Rowell, Lillian F. Lien, John R. Guyton, Jeanette J. McCarthy

“…These variants were clustered downstream of LYPLAL1, which encodes a lipase/esterase expressed in adipose tissue, a locus previously identified as having sex-specific effects on central obesity. …”
Get full text

Disrupted Endothelial Cell Layer and Exposed Extracellular Matrix Proteins Promote Capture of Late Outgrowth Endothelial Progenitor Cells by Jing Zhao, Claudia-Gabriela Mitrofan, Sarah L. Appleby, Nicholas W. Morrell, Andrew M. L. Lever

“…The interaction was not adhesion molecule-dependent and not enhanced by EC activation. LO-EPC expressed high levels of the VE-Cadherin which may explain these findings. …”
Get full text

Growth Hormone-Releasing Hormone and Its Analogues: Significance for MSCs-Mediated Angiogenesis by Xiangyang Xia, Quanwei Tao, Qunchao Ma, Huiqiang Chen, Jian’an Wang, Hong Yu

“…GHRH and its agonists are proangiogenic in responsive tissues including tumors, and GHRH antagonists have been tested as antitumor agents through their ability to suppress angiogenesis and cell growth. GHRH-R is expressed by MSCs and evolving work from our laboratory indicates that treatment of MSCs with GHRH agonists prior to cell transplantation markedly enhanced the angiogenic potential and tissue reparative properties of MSCs through a STAT3 signaling pathway. …”
Get full text

Motivational Factors and Cannabis Use Intention among Juvenile Offenders: Direct, Mediating, and Moderating Effects by Isabel M. Herrera-Sánchez, Silvia Medina-Anzano, Samuel Rueda-Méndez

“…Moderation analysis revealed that when risk perceptions and action self-efficacy were high, female JOs expressed a stronger intention not to use cannabis than their male counterparts. …”
Get full text

Population aging: a look from nursing practice based on the Nola J. Pender model by María de los Ángeles Villegas Dorticós, Zenia Tamara Sánchez García, Omayda Urbina Laza, Noel Alberto Pardillo Mustelier, Jacquelin Cordero Odery, Maydelis Gómez Valdivia

“…The theoretical aspects expressed by her, her main assumptions and her relationship with population aging are analyzed, in addition to exposing her theoretical contributions, the importance of her application for the family, the community and her contribution to the development of nursing not only in Cuba but in the world; if we start from the fact that Cuba is among the oldest countries in Latin America. …”
Get full text

High-Throughput Sequencing Reveals Diverse Sets of Conserved, Nonconserved, and Species-Specific miRNAs in Jute by Md. Tariqul Islam, Ahlan Sabah Ferdous, Rifat Ara Najnin, Suprovath Kumar Sarker, Haseena Khan

“…A group of plant microRNAs are evolutionarily conserved; however, others are expressed in a species-specific manner. Jute is an agroeconomically important fibre crop; nonetheless, no practical information is available for microRNAs in jute to date. …”
Get full text

The Gingiva from the Tissue Surrounding the Bone to the Tissue Regenerating the Bone: A Systematic Review of the Osteogenic Capacity of Gingival Mesenchymal Stem Cells in Preclinic... by Gamilah Al-Qadhi, Iman Aboushady, Niyaz Al-Sharabi

“…GMSCs showed great proliferation capacity and expressed recognized mesenchymal stem cell markers, particularly CD90. …”
Get full text

Multi-valued mappings on Pompeiu-Hausdorff fuzzy b-metric spaces and a common fixed point result by Noreddine Makran, Stojan N. Radenović

“…Unlike traditional logic theory, where an element either belongs to the set or does not, in fuzzy logic, the affiliation of the element to the set is expressed as a number from the interval [0, 1]. Methods: The theory of a fixed point in fuzzy metric spaces can be viewed in different ways, one of which involves the use of fuzzy logic. …”
Get full text

Assessment of Polypharmacy, Drug Use Patterns, and Associated Factors at the Edna Adan University Hospital, Hargeisa, Somaliland by Temesgen Sidamo, Alemu Deboch, Mohamed Abdi, Fikru Debebe, Khalid Dayib, Tamrat Balcha Balla

“…The association between total polypharmacy and different variables was analyzed using multivariable binary logistic regression and expressed as an odds ratio (OR) and 95% confidence interval (CI). …”
Get full text

QuEChERS Method Followed by Solid Phase Extraction Method for Gas Chromatographic-Mass Spectrometric Determination of Polycyclic Aromatic Hydrocarbons in Fish by Mona Khorshid, Eglal R. Souaya, Ahmed H. Hamzawy, Moustapha N. Mohammed

“…The measurement uncertainty is expressed as expanded uncertainty and in terms of relative standard deviation (at 95% confidence level) is ±12%. …”
Get full text

Adaptive potential of durum wheat (Triticum durum Desf.) varieties of Azerbaijan by Kh. N. Rustamov, Z. I. Akparov, M. A. Abbasov

“…Adaptability coefficients (0.81–1.23) showed that the response of the studied varieties to unfavorable conditions was highly expressed. Indigenous landraces ‘Ag bughda’ and ‘Bozak’, old breeding varieties ‘Arandani’, ‘Ag bughda 13’, ‘Kahraba’ and ‘Mirbashir 50’, and new cultivars ‘Karagilchig 2’ and ‘Barakatli 95’ had the highest adaptability coefficients. …”
Get full text

Identification of a Novel PPAR Signature for Predicting Prognosis, Immune Microenvironment, and Chemotherapy Response in Bladder Cancer by Ke Zhu, Wen Deng, Hui Deng, Xiaoqiang Liu, Gongxian Wang, Bin Fu

“…The RNA sequencing data and clinical information of BLCA patients were acquired from The Cancer Genome Atlas (TCGA). The differentially expressed PPAR-targeted genes were investigated. Cox analysis and least absolute shrinkage and selection operator (LASSO) analysis were performed for screening prognostic PPAR-targeted genes and constructing the prognostic PPAR signature and then validated by GSE13507 cohort and GSE32894 cohort. …”
Get full text

The quintessence of legal consciousness as a factor of deviant behavior by S. H. Pevko

“…As a result, it has been found that the factors influencing legal awareness that cause deviant behavior are inadequate level of legal education, which is manifested in the low level of legal psychology as a component of legal awareness; improper level of implementation of laws, which is expressed in legal nihilism as a reflection of the attitude to the requirements of the legal norms of citizens, legal entities and persons residing in Ukraine; and low economic level of the population. …”
Get full text

CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation by Minghui Tan, Caihui Cha, Yongheng Ye, Jifeng Zhang, Sumei Li, Fengming Wu, Sitang Gong, Guoqing Guo

“…Collapsin response mediator proteins (CRMPs) are highly expressed in the developing nervous system, mediating growth cone guidance, neuronal polarity, and axonal elongation. …”
Get full text

Thin Air Resulting in High Pressure: Mountain Sickness and Hypoxia-Induced Pulmonary Hypertension by Jan Grimminger, Manuel Richter, Khodr Tello, Natascha Sommer, Henning Gall, Hossein Ardeschir Ghofrani

“…It furthermore describes the characteristic mechanisms of adaptation to life in hypobaric hypoxia expressed by the three major ethnic groups permanently dwelling at high altitude. …”
Get full text

Development of a Cell-Based Functional Assay for the Detection of Clostridium botulinum Neurotoxin Types A and E by Uma Basavanna, Tim Muruvanda, Eric W. Brown, Shashi K. Sharma

“…Here, we describe a cell-based assay utilizing a fluorescence reporter construct expressed in a neuronal cell model to study toxin activity in situ. …”
Get full text