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9741
Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum
Published 2025-01-01“…These findings, together with the lower mRNA expression of proinflammatory genes in the head kidney and the higher mortality rates observed in this group, suggest a potential impairment of the immune response.…”
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9742
Efficacy and predictors of response to somatostatin analogues in patients with ectopic ACTH syndrome
Published 2024-12-01“…Significant factors determining the response to SSAs after 6 months of treatment are expression status of SSTR5 and NET localization.…”
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9743
Effects of deoxynivalenol contaminated corn distiller's dried grains with solubles on growth performance, body composition, immunological response, and gastrointestinal health in y...
Published 2025-01-01“…Additionally, interleukin 1β (IL-1β) expression significantly increased in the cecal tonsil by day 28 with 15 and 20% DDGS inclusions (P = 0.002). …”
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9744
Sodium Butyrate: A Multifaceted Modulator in Colorectal Cancer Therapy
Published 2025-01-01“…RT-PCR was used to determine changes in the expression of critical pro-apoptotic players (<i>BAX</i>, <i>CASP3</i>, <i>PUMA</i>, <i>TP53</i>), anti-apoptotic facilitators (<i>BCL</i>-2, <i>MCL-1</i>), cell division regulators (<i>PCNA</i>, <i>Ki-67</i>, <i>CDKN</i>1), and inflammation genes (<i>NF-κB</i>). …”
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9745
Hepatic Abnormal Secretion of Apolipoprotein C3 Promotes Inflammation in Aortic Dissection
Published 2025-02-01“…Methods and Results In vivo, adeno‐associated virus was used to knock down hepatic apo C3 expression in an AD mouse model to assess the impact of liver‐derived apo C3 on the development of AD. …”
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9746
The Effect of Diabetes-Associated Autoantigens on Cell Processes in Human PBMCs and Their Relevance to Autoimmune Diabetes Development
Published 2013-01-01“…After 72 hours, gene expression was evaluated by high-density gene microarray. …”
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9747
Semaphorin-4D signaling in recruiting dental stem cells for vascular stabilization
Published 2025-01-01“…Furthermore, the m6A methylation levels of total RNA and the expression of Methyltransferase-like 3 (METTL3) were assessed under conditions of Sema4D treatment in vitro. …”
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9748
Organic rare earth feed additive to enhance Penaeus monodon’s muscle quality: A comprehensive insights into texture, amino acid, and fatty acid composition
Published 2025-03-01“…Additionally, the relative expression levels of muscle growth-related genes PI3K (Phosphoinositide 3-kinase), TOR (target of rapamycin), AKT (Protein kinase B), S6K1 (ribosomal protein S6 kinase 1) and 4E-BP1 (4E-binding protein 1) were significantly higher in shrimp muscle compared to the CON group (P < 0.05). …”
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9749
Plasma myeloperoxidase interactions with cadmium, lead, arsenic, and selenium and their impact on chronic kidney disease
Published 2025-01-01“…Metal exposure is a risk factor for CKD, and is also correlated to MPO expression, with specific MPO genotypes linked to MPO expression. …”
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9750
Lunar and Martian gravity alter immune cell interactions with endothelia in parabolic flight
Published 2025-02-01“…Focus was set on floating speed, cell adhesion, surface molecule expression and cytoskeletal reorganization under basal and TNF-induced inflammatory environment. …”
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9751
Effects of Macleaya cordata extract supplementation in low-protein, low-fishmeal diets on growth, hematology, intestinal histology, and microbiota in largemouth bass (Micropterus s...
Published 2025-03-01“…Supplementing MCE in low-fishmeal or low-protein diets significantly increased the abundance of Firmicutes in the intestinal microbiota (P < 0.05). Additionally, the expression levels of the inflammatory factors IL-10 and TGF-β1 were reduced. …”
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9752
Utilisation of the Innovative [18F]-Labelled Radiotracer [18F]-BIBD-071 Within HR+ Breast Cancer Xenograft Mouse Models
Published 2025-01-01“…Immunofluorescence confirmed robust aromatase expression in MCF-7 cells, which was correlated with [18F]BIBD-071 tumour uptake. …”
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9753
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis
Published 2025-02-01“…In addition, the influences on cellular apoptosis, mitochondrial dynamics, mitophagy, and neuroinflammation were further investigated.ResultsOptn expression was increased in the spinal cord of SOD1G93A mice at the pre-symptomatic phase, but decreased after disease onset. …”
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9754
Helicobacter pylori reduces METTL14-mediated VAMP3 m6A modification and promotes the development of gastric cancer by regulating LC3C-mediated c-Met recycling
Published 2025-01-01“…METTL14 and VAMP3 expression levels are downregulated notably in cancerous tissues of patients with GC. …”
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9755
Evaluation of Serum Leucine-Rich Alpha-2 Glycoprotein as a New Inflammatory Biomarker of Inflammatory Bowel Disease
Published 2021-01-01“…This study is aimed at evaluating the utility of serum LRG as a potential inflammatory marker for IBD and to investigate the LRG gene expression in peripheral blood mononuclear cells (PBMCs) as a possible source of serum LRG. …”
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9756
Characterization of β-Actin Promoter from Nile Tilapia (Oreochromis niloticus)
Published 2008-07-01“…Furthermore, tiBP sequence in ptiBP-EGFP construct could regulated GFP expression in muscle of zebrafish embryos injected with the construct. …”
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9757
Identification of CENPM as a key gene driving adrenocortical carcinoma metastasis via physical interaction with immune checkpoint ligand FGL1
Published 2025-01-01“…Methods Weighted gene co‐expression network analysis (WGCNA) and functional enrichment analysis were conducted to identify ACC metastasis‐related genes. …”
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9758
miR-10a in Peripheral Blood Mononuclear Cells Is a Biomarker for Sepsis and Has Anti-Inflammatory Function
Published 2020-01-01“…In addition, low miR-10a expression had a diagnostic value for sepsis and a prognostic value for 28-day mortality in receiving operating characteristic analysis. …”
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9759
Exosomes Derived from Mesenchymal Stem Cells Ameliorate Hypoxia/Reoxygenation-Injured ECs via Transferring MicroRNA-126
Published 2019-01-01“…The viability, migration, tube formation ability, and apoptosis of ECs were measured. miR-126 and proangiogenic/growth factor (VEGF, EGF, PDGF, and bFGF) expressions were detected by qRT-PCR. Akt, p-Akt, p-eNOS, and cleaved caspase-3 expressions were examined by western blot. …”
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9760
Unraveling the association and regulatory role of miR-146b-5p in coronary artery disease
Published 2025-02-01“…In the study, we focus on the expression of miR-146b-5p in peripheral blood mononuclear cells (PBMCs) of patients with CAD and preliminarily investigate its function and underlying mechanism. …”
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