Aqp 9 and Brain Tumour Stem Cells by Guri Fossdal, Einar O. Vik-Mo, Cecilie Sandberg, Mercy Varghese, Mari Kaarbø, Emily Telmo, Iver A. Langmoen, Wayne Murrell

“…However, immunostaining did not reveal increased protein expression of aqp9 in the tumourspheres containing progenitor cells; in contrast, its expression (both mRNA and protein) was high in differentiated cultures. …”
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Comparisons of Vitreal Angiogenic, Inflammatory, Profibrotic Cytokines, and Chemokines Profile between Patients with Epiretinal Membrane and Macular Hole by Lu Chen, Weiwei Zhang, Ping Xie, Jiangdong Ji, Huiming Qian, Songtao Yuan, Qinghuai Liu, Zizhong Hu

“…This study aimed to investigate if there is a difference in vitreal cytokines expression between patients with iERM and iMH. Methods. …”
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Development of a Novel Prognostic Model for Lung Adenocarcinoma Utilizing Pyroptosis-Associated LncRNAs by Hong-Yan Bai, Tian-Tian Li, Li-Na Sun, Jing-Hong Zhang, Xiu-He Kang, Yi-Qing Qu

“…Coexpression analysis and differential expression analysis of these genes and long noncoding RNAs (lncRNAs) found that three lncRNAs (AC012615.1, AC099850.3, and AO0001453.2) had significant differences in expression between cancer tissues and noncancerous tissues. …”
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Physical exercise improves the premature muscle aging and lifespan reduction induced by high-salt intake and muscle CG2196(salt) overexpression in Drosophila by Dengtai Wen, Yiling Chen, Xu Tian, Wenqi Hou

“…Muscle CG2196 (salt) gene and dSir2 gene were over-expressed by building mef2-gal4/UAS system. The results showed that both physical exercise and muscle dSir2 gene overexpression prevented HSI-induced and muscle salt overexpression-induced accelerated age-related decline of climbing index, climbing endurance, muscle NAD+ level, SOD activity level, dSir2 expression, and dFOXO expression, and they also prevented HSI-induced and muscle salt overexpression-induced accelerated age-related increase in muscle ROS level, MDA level, and salt gene expression. …”
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Comprehensive Analysis of N6-Methyladenosine RNA Methylation Regulators in the Diagnosis and Subtype Classification of Acute Myocardial Infarction by Xianpei Wang, Ying Wu, Ruoyao Guo, Linwei Zhao, Juanjuan Yan, Chuanyu Gao

“…The GEO database was used to get the gene expression profiles of patients with and without AMI, and bioinformatics assays of genes with differently expressed expression were performed. …”
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Deciphering the Regulatory Network of Some Key Drought-responsive Genes and microRNAs in Canola by Maryam Pasandideh Arjmand, Naser Farrokhi, Habibollah Samizadeh Lahiji, Mohammad Mohsenzadeh Golfazani

“…This study was conducted to obtain a greater insight into the drought-related hub genes, their regulatory network and relative expression pattern in tolerant and susceptible genotypes of Canola under drought stress. …”
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Extracellular Vesicle-Loaded Oncogenic lncRNA NEAT1 from Adipose-Derived Mesenchymal Stem Cells Confers Gemcitabine Resistance in Pancreatic Cancer via miR-491-5p/Snail/SOCS3 Axis by Rongxiang Wu, Zhan Su, Le Zhao, Ruifeng Pei, Yiren Ding, Deqiang Li, Shuo Zhu, Lu Xu, Wei Zhao, Wuyuan Zhou

“…Microarray profile suggested a differentially expressed lncRNA NEAT1 in PCa, and we determined its expression in PCa cells. …”
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Pan-cancer analysis shows that TNFSF4 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including liver cancer by Zhaoda Deng, Lincheng Li, Zihe Meng, Guineng Zeng, Rui Cao, Rong Liu

“…TNFSF4 expression correlated with the expression of immune checkpoint genes and could influence various drug sensitivity. …”
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Potential of Inducible Nitric Oxide Synthase as a Therapeutic Target for Allergen-Induced Airway Hyperresponsiveness: A Critical Connection to Nitric Oxide Levels and PARP Activity by Salome’ V. Ibba, Mohamed A. Ghonim, Kusma Pyakurel, Matthew R. Lammi, Anil Mishra, A. Hamid Boulares

“…Although expression of inducible NO synthase (iNOS) in the lungs of asthmatics and associated nitrosative damage are established, iNOS failed as a therapeutic target for blocking airway hyperresponsiveness (AHR) and inflammation in asthmatics. …”
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Comparative Study of Regulatory T Cell Function of Human CD25+CD4+ T Cells from Thymocytes, Cord Blood, and Adult Peripheral Blood by Wakae Fujimaki, Nozomu Takahashi, Kei Ohnuma, Masayoshi Nagatsu, Hiromi Kurosawa, Satoko Yoshida, Nam H. Dang, Takehiko Uchiyama, Chikao Morimoto

“…CB CD25+CD4+ T cells displayed low-FOXP3 protein expression level and had no suppressive activity. In contrast, CD25+CD4+ T cells from thymocytes or APB expressed high expression level of FOXP3 protein associated with significant suppressive activity. …”
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FKBP4 Accelerates Malignant Progression of Non-Small-Cell Lung Cancer by Activating the Akt/mTOR Signaling Pathway by Wen Meng, Jingfei Meng, Hong Jiang, Xing Feng, Dongshan Wei, Qingsong Ding

“…Objective. To study the expression, biological function, and mechanism of FKBP4 in non-small-cell lung cancer (NSCLC). …”
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Noncanonical Roles of hα-syn (A53T) in the Pathogenesis of Parkinson’s Disease: Synaptic Pathology and Neuronal Aging by Qing-Jun Wang, An-Di Chen, Hai-Chao Chen, Dong-Xin Wang, Yi-Ting Cai, Jie Yin, Yu-Hong Jing, Li-Ping Gao

“…In the striatum, hα-syn expression was high, CaMKβ-2 and NR2B expression decreased, and active synapses reduced. …”
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Uniaxial Cyclic Tensile Stretching at 8% Strain Exclusively Promotes Tenogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stromal Cells by Hui Yin Nam, Belinda Pingguan-Murphy, Azlina Amir Abbas, Azhar Mahmood Merican, Tunku Kamarul

“…The tenogenic, osteogenic, adipogenic, and chondrogenic differentiation potential of hMSCs were evaluated using biochemical assays, extracellular matrix expressions, and selected mesenchyme gene expression markers; and were compared to primary tenocytes. …”
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The Involvement of Notch1-RBP-Jk/Msx2 Signaling Pathway in Aortic Calcification of Diabetic Nephropathy Rats by Caipan Gong, Li Li, Chunmei Qin, Weihua Wu, Qi Liu, Ying Li, Linwang Gan, Santao Ou

“…Diabetic rats with vascular calcification exhibited mineral deposits in aortic intima-media accompanied by decreased expression of VSMC markers and increased expression of osteogenic markers. …”
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Development of immune-derived molecular markers for preeclampsia based on multiple machine learning algorithms by Zhichao Wang, Long Cheng, Guanghui Li, Huiyan Cheng

“…We used bioinformatics tools to analyze gene expression data from the Gene Expression Omnibus (GEO) database using the GEOquery package in R. …”
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The Long Noncoding RNA Gm9866/Nuclear Factor-κB Axis Promotes Macrophage Polarization by Xiaomin Liao, Xianxian Ruan, Xiubing Chen, Biaolin Zheng, Xianbin Wu, Zhejun Deng, Zhe Yang, Feng Wang, Shanyu Qin, Haixing Jiang

“…Fluorescence in situ hybridization revealed that long noncoding RNA Gm9866 was expressed mainly in the nucleus. Real-time polymerase chain reaction analysis showed that overexpression of long noncoding RNA Gm9866 in RAW264.7 cells further promoted the expression of M2 markers MRC1 (macrophage mannose receptor 1) and MRC2 (macrophage mannose receptor 2). …”
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Balancing CIK Cell Cancer Immunotherapy and PPAR Ligands: One Potential Therapeutic Application for CNS Malignancies by Kira Vordermark, JingJing Pu, Amit Sharma, Jarek Maciacyzk, Ingo G. H. Schmidt‐Wolf

“…Equally important are the hints suggesting peroxisome proliferator‐activated receptors (PPARs) ligands being co‐expressed in the central nervous system (CNS). This provides a rationale about investigating the possible synergistic effect of CIK cells and PPARs. …”
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Comparative transcriptomic analysis of primary endometrial cancer and bone metastatic cancer: metastasis-associated genes and abnormal cell cycle regulation by Qinmin Wu, Feng Li, Yunlong Zhang, Siying Li, Chuan Xiang

“…In this study, we aim to determine the changes in gene expression profiles in EC bone metastasis and explore the transcriptomic differences between metastatic and primary lesions. …”
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Endothelial protease-activated receptor 4: impotent or important? by Rahul Rajala, Rahul Rajala, Rahul Rajala, Courtney T. Griffin, Courtney T. Griffin

“…As a result, we claim PAR4 is not an impotent receptor because it is low expressing, but rather PAR4 is low expressing because it is a very potent receptor. …”
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Leptin Promoted IL-17 Production from ILC2s in Allergic Rhinitis by Yanhui Wen, Qingxiang Zeng, Xi Luo, Renqiang Ma, Yiquan Tang, Wenlong Liu

“…We also found that leptin induced RORγt and Ahr expression by ILC2. Moreover, leptin-induced IL-17-producing ILC2 concomitantly expressed IL-5 and IL-13. …”
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