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2941
Characterization of the Merkel Cell Carcinoma miRNome
Published 2014-01-01“…MicroRNAs have been implicated in various skin cancers, including melanoma, squamous cell carcinoma, and basal cell carcinoma; however, the expression of microRNAs and their role in Merkel cell carcinoma (MCC) have yet to be explored in depth. …”
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2942
TREM2 promotes the formation of a tumor-supportive microenvironment in hepatocellular carcinoma
Published 2025-01-01“…Abstract Background Triggering receptor expressed on myeloid cells 2 (TREM2), a surface receptor predominantly expressed on myeloid cells, is a major hub gene in pathology-induced immune signaling. …”
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2943
Isolation and Characterisation of Mesenchymal Stem Cells from Rat Bone Marrow and the Endosteal Niche: A Comparative Study
Published 2018-01-01“…CB-MSCs and BM-MSCs both expressed MSC (CD73/CD90/CD105); embryonic (Nanog) and osteogenic markers (Runx2, osteocalcin) but no hematopoietic markers (CD45). …”
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2944
Identifying MTHFD1 and LGALS4 as Potential Therapeutic Targets in Prostate Cancer Through Multi-Omics Mendelian Randomization Analysis
Published 2025-01-01“…Candidate genes were further verified through TCGA-based gene expression profile, survival analysis, and immune microenvironment evaluations. …”
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2945
Melanoma Development and Progression Are Associated with Rad6 Upregulation and β-Catenin Relocation to the Cell Membrane
Published 2014-01-01“…We have previously demonstrated that Rad6 and β-catenin enhance each other's expression through a positive feedback loop to promote breast cancer development/progression. …”
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2946
Clinical Feature of Intrahepatic B-Lymphocytes in Chronic Hepatitis B
Published 2014-01-01“…In this study, fifty seven hepatitis B surface antigen (HBsAg) positive and HBeAg negative patients were studied to determine the expression of CD20, a cell surface marker expressed on B-cells, in liver biopsy sections using immunohistochemistry. …”
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2947
Crucial Genes in Aortic Dissection Identified by Weighted Gene Coexpression Network Analysis
Published 2022-01-01“…Specifically, gene expression profiling helps illustrate the potential mechanism of aortic dissection in terms of gene regulation and its modification by risk factors. …”
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2948
Comprehensive Analysis of Transcriptome Sequencing Data in the Lung Tissues of COPD Subjects
Published 2015-01-01“…A total of 2312 genes were differentially expressed between the lung tissues of COPD and control subjects (false discovery rate corrected q<0.01). …”
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2949
lnc-MRGPRF-6:1 Promotes ox-LDL-Induced Macrophage Ferroptosis via Suppressing GPX4
Published 2023-01-01“…Eventually, lnc-MRGPRF-6:1 was highly expressed in the monocyte-derived macrophages of CAD patients and was negatively correlated with the expression of GPX4. …”
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2950
Transcriptome Analysis Revealed the Molecular Mechanism of Acetic Acid Increasing <i>Monascus</i> Pigment Production in <i>Monascus ruber</i> CICC41233
Published 2025-01-01“…Gene expression analysis showed that the relative expression levels of MP synthesis genes (<i>MpPKS5</i>, <i>MppA</i>, <i>MpFasB</i>, <i>MppB</i>, <i>MppD</i>, and <i>MppR2</i>) were significantly up-regulated under acetic acid conditions. …”
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2951
Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis
Published 2025-01-01“…Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of RNA-binding proteins (RBPs), which are critical for alternative mRNA splicing and translational control in rheumatoid arthritis (RA). …”
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2952
“For mine is the bitter, the ale and the lager”: Parodic prayer and the spirituality of humour
Published 2022-12-01“…This article reviews that history, showing that medieval parodic prayers arose from within the Church and often expressed ethical concerns through satire. They could also go further, speaking to the relationship with God that is at the heart of Christian spirituality. …”
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2953
The proneural transcription factor Atoh1 promotes odontogenic differentiation in human dental pulp stem cells (DPSCs)
Published 2025-01-01“…Results DPSCs harboring the Atoh1 expression vector exhibited an approximately 3,000-fold increase in the expression of Atoh1 compared to the negative control, leading to increased DPSC proliferation in the growth medium (P < 0.05). …”
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2954
Evaluating H2BC9 as a potential diagnostic and prognostic biomarker in head and neck squamous cell carcinoma
Published 2025-01-01“…Abstract Background Histone H2B is highly expressed in many types of cancers and is involved in cancer development. …”
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2955
The Anti-proliferative Effect of a Novel Glutaminase Inhibitor IN-3 on Prostate Cancer Cells
Published 2024-09-01“…GLS1 expression was significantly higher than GLS2 expression with p-values lower than 0.001. …”
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2956
Human Placenta-Derived Mesenchymal Stem Cells Ameliorate Diabetic Neuropathy via Wnt Signaling Pathway
Published 2022-01-01“…Bax in the PMSC group expressed less than the control group. In contrast, the expressions of β-catenin and DVL1 were higher compared with that in the control group on the 14th and 28th days. …”
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2957
Molecular Signatures of Human Chronic Atrial Fibrillation in Primary Mitral Regurgitation
Published 2021-01-01“…We aimed to compare the gene expression profiles of patients with degenerative MR in AFib and sinus rhythm (SR) for a clearer picture of AFib pathophysiology. …”
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2958
A simple and reliable method for claustrum localization across age in mice
Published 2024-02-01“…Finally, exposure to environmental novelty enhanced the expression of the neuronal activation marker c-Fos in the claustrum region. …”
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2959
Heme Oxygenase 1/Peroxisome Proliferator-Activated Receptor Gamma Pathway Protects Intimal Hyperplasia and Mitigates Arteriovenous Fistula Dysfunction by Regulating Oxidative Stres...
Published 2022-01-01“…Additionally, AVF significantly upregulated HO-1 and PPAR-γ and downregulated MMP9, and COPP pretreatment and HO-1 normal expression further upregulated and downregulated their expression. …”
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2960
Identification of KRT16 and ANXA10 as cell cycle regulation genes for lung adenocarcinoma based on self-transcriptome sequencing of surgical samples and TCGA public data mining
Published 2025-01-01“…The expression was validated at mRNA and protein levels, and the gene knockdown was used to examine the impact and underlying mechanisms on lung cancer cells. …”
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