Elotuzumab Enhances CD16-Independent NK Cell-Mediated Cytotoxicity against Myeloma Cells by Upregulating Several NK Cell-Enhancing Genes by Yan-Hua Wang, Shotaro Hagiwara, Hiroshi Kazama, Yuki Iizuka, Norina Tanaka, Junji Tanaka

“…Furthermore, the augmentation of the antitumor effects of CD16-independent NK cells upon pretreatment with Elo enhanced the expression of CRTAM, TNFRSF9, EAT-2, and FOXP3 genes and reduced the expression of HSPA6. …”
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Actin-Binding Proteins as Potential Biomarkers for Chronic Inflammation-Induced Cancer Diagnosis and Therapy by Yu-Gui Zhang, Jiang-Tao Niu, Hong-Wei Wu, Xin-Lei Si, Shu-Juan Zhang, Dong-Hui Li, Tian-Tian Bian, Yue-Feng Li, Xing-Ke Yan

“…In recent years, a variety of ABPs have been found to be abnormally expressed in various cancers, indicating that the detection and interventions of unusual ABP expression to alter this are available for the treatment of cancer. …”
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Evaluation and Immunolocalization of BMP4 and FGF8 in Odontogenic Cyst and Tumors by Neeti Swarup, Meghanand T. Nayak, Zoya Chowdhary, Monica Mehendiratta, Shikha Khatana, Su Jung Choi, Chandarani Sagolsem

“…Both growth factors were actively expressed in different stages of tooth development. …”
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Prognostic significance of neutrophil extracellular trap-related genes in childhood acute lymphoblastic leukemia: insights from multi-omics and in vitro experiment by Cheng Chen, Yu Ma, Yadai Gao, Huiqing Ge, Xiaochun Zhang

“…Differentially expressed genes (DEGs) were identified from GSE26713 and differentially expressed NETRGs (DE-NETRGs) were obtained by overlapping DEGs with NETRGs. …”
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Construction of a circRNA-miRNA-mRNA Regulatory Network for Coronary Artery Disease by Bioinformatics Analysis by Zebo Zhang, Haiyan Qian, Li Wang, Zhenbo Tao, Keai Cheng, Kaiyue Wang, Yanqing Xie, Lina Zhang

“…In this study, we aim to construct a circRNA-related competing endogenous RNA (ceRNA) network in CAD. Methods. The gene expression profiles of CAD were obtained from Gene Expression Omnibus datasets. …”
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Study of the role of transmembrane emp24 domain-containing protein 2 in oral squamous cell carcinoma by RUAN Zhao-wei, JIAO Xue-feng, XIAO Gao-tian, CHEN Jin-ling, LI Jun, LV Shu-ying

“…Methodology A bioinformatics analysis was first conducted to explore TMED2 expression in OSCC and its relation with overall survival. …”
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Blood Transcriptional Signatures for Disease Progression in a Rat Model of Osteoarthritis by Michał Korostyński, Natalia Małek, Marcin Piechota, Katarzyna Starowicz

“…We have sought to determine the time course of alterations in peripheral blood gene expression profile associated with the development of OA. …”
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Transcriptome analysis of testis in response to silencing of Piwi2 sheds light on spermatogenesis in the mud crab Scylla paramamosain by Tao Wang, Li Lu, Fang Liu, An Liu, Haihui Ye

“…It had a high expression level at stage I, and that expression significantly decreased at stage II but subsequently increased at stage III. …”
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Evaluation of Podoplanin in Oral Leukoplakia and Oral Squamous Cell Carcinoma by Ashok Patil, Kishor Patil, Suyog Tupsakhare, Mahesh Gabhane, Shrikant Sonune, Shilpa Kandalgaonkar

“…Recent studies have demonstrated that podoplanin was expressed in some dysplastic lesions adjacent to primary oral cancers suggesting that podoplanin expression may occur in early oral tumorigenesis and lymphangiogenesis and therefore is related to tumor growth. …”
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AEBP1 Promotes Glioblastoma Progression and Activates the Classical NF-κB Pathway by Kai Guo, Lei Song, Jianyong Chang, Peicheng Cao, Qi Liu

“…AEBP1 could upregulate the level of IκBα phosphorylation, decrease IκBα expression, activate the NF-κB signaling pathway, and promote the expression of downstream oncogenes. …”
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Pan-cancer analysis and single-cell analysis identifies the CENPN as a biomarker for survival prognosis and immunotherapy by Nie Zhang, Zhuoying He, Xuejin Qin, Ke Han, Zhengchun Zhu, Fei Zhong

“…Results The findings demonstrated that CENPN expression was elevated in the majority of cancer types and differentially expressed across molecular and immune subtypes. …”
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Exploration of the shared diagnostic genes and molecular mechanism between obesity and atherosclerosis via bioinformatic analysis by Wenrong An, Kegong Tang, Juan Liu, Wenfei Zheng, Guoxia Li, Yunsheng Xu

“…The microarray datasets of OB and AS were obtained from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) analysis and the weighted gene co-expression network analysis (WGCNA) were conducted to identify the shared genes. …”
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Anther transcriptomes in cold-tolerant rice cultivars tend to show insensitive responses by Koichi Yamamori, Seiya Ishiguro, Kei Ogasawara, Kayyis Muayadah Lubba, Kaien Fujino, Kazumitsu Onishi, Yutaka Sato, Yuji Kishima

“…In this study, we explored the changes in the transcriptome of anthers from 13 rice lines with different cold tolerance grown under control conditions or exposed to 4 days of cold stress to look for correlations between cold tolerance at the booting stage and expression levels. When examining the overall expression patterns in anthers at low temperature, the cold-tolerant lines tended to have relatively few highly expressed genes, and the expression levels of ribosome-related genes tended to be lower in cold-tolerant lines than in cold-sensitive lines. …”
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Downregulation of VRK1 Inhibits Progression of Lung Squamous Cell Carcinoma through DNA Damage by Ning Du, Boxiang Zhang, Yunfeng Zhang

“…The expression of VRK1 mRNA was detected in 25 LUSC clinical tissue samples by RT-PCR. …”
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Identification of critical biomarkers and immune landscape patterns in glioma based on multi-database by Hanzhang Yuan, Jingsheng Cheng, Jun Xia, Zeng Yang, Lixin Xu

“…Patients and methods Differentially expressed genes (DEGs) of glioma were downloaded from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. …”
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Subculture of Germ Cell-Derived Colonies with GATA4-Positive Feeder Cells from Neonatal Pig Testes by Kyung Hoon Lee, Won Young Lee, Jin Hoi Kim, Chan Kyu Park, Jeong Tae Do, Jae Hwan Kim, Young Suk Choi, Nam Hyung Kim, Hyuk Song

“…Immunocytochemistry data revealed that the FFCs expressed GATA-binding protein 4 (GATA4), which is also detected in the cells of neonatal testes and total testicular cells, and that the expression of GATA4 was decreased in used old feeder cells. …”
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A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy by Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short

“…EpCAM is an attractive therapeutic target because of its expression in most solid tumors. However, targeting EpCAM has been challenging because it is also highly expressed in normal epithelial tissues. …”
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Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson’s disease model mice by Wei Song, Zi-ming Zhou, Le-le Zhang, Hai-feng Shu, Jin-ru Xia, Xia Qin, Rong Hua, Yong-mei Zhang

“…However, the role of peripheral immune responses, particularly triggering receptor expressed on myeloid cells-1 (TREM-1), in PD remains unclear. …”
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The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity by Daniel Torrente, Enming J. Su, Alí Francisco Citalán-Madrid, Gerald P. Schielke, Daniel Magaoay, Mark Warnock, Tamara Stevenson, Kris Mann, Flavie Lesept, Nathalie Delétage, Manuel Blanc, Erin H. Norris, Denis Vivien, Daniel A. Lawrence

“…Abstract The thrombolytic protease tissue plasminogen activator (tPA) is expressed in the CNS, where it regulates diverse functions including neuronal plasticity, neuroinflammation, and blood-brain-barrier integrity. …”
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Les préposition de To et For : grammaticalisation et subjectivation by Dominique Boulonnais

“…Prepositional TO is analyzed as expressing telicity, whereas FOR, which locates the referent of its complement in a separate space, expresses cause and goal. …”
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