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  1. 2861

    RNA helicase MOV10 suppresses fear memory and dendritic arborization and regulates microtubule dynamics in hippocampal neurons by Temirlan Shilikbay, Aatiqa Nawaz, Megan Doon, Stephanie Ceman

    Published 2025-02-01
    “…Abstract Background RNA helicase MOV10 is highly expressed in postnatal brain and associates with FMRP and AGO2, suggesting a role in translation regulation in learning and memory. …”
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    Article
  2. 2862

    Cross-Cultural Gender-Based Investigation of Filipino and Chinese Facebook Users’ Disagreement Strategies by Joan C. Ravago, John Arvin V. De Roxas, Joel M. Torres, Daisy O. Casipit, Mercedita M. Reyes

    Published 2024-06-01
    “… Objectives: This study analyzed how Filipino and Chinese individuals express disagreements on Facebook, focusing on gender dynamics. …”
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    Article
  3. 2863

    Discovery of paradoxical genes: reevaluating the prognostic impact of overexpressed genes in cancer by Dequan Liu, Lei Liu, Xiangyu Che, Guangzhen Wu

    Published 2025-01-01
    “…However, recent advancements in bioinformatics have revealed that many highly expressed genes in tumors are associated with better patient outcomes. …”
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    Article
  4. 2864

    Statistical identification of cell type-specific spatially variable genes in spatial transcriptomics by Lulu Shang, Peijun Wu, Xiang Zhou

    Published 2025-01-01
    “…Here, we present Celina, a statistical method for systematically detecting cell type-specific SVGs (ct-SVGs)—a subset of SVGs exhibiting distinct spatial expression patterns within specific cell types. Celina utilizes a spatially varying coefficient model to accurately capture each gene’s spatial expression pattern in relation to the distribution of cell types across tissue locations, ensuring effective type I error control and high power. …”
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    Article
  5. 2865

    An exploratory study of INPP4B, a biomarker of gemcitabine chemoresistance in pancreatic cancer by REN Jiaqiang, WU Shuai, SU Tong, LI Jie, HAN Liang, WU Zheng

    Published 2024-12-01
    “…Co-expressed genes were screened using real-time fluorescence quantitative polymerase chain reaction (RTFQ-PCR), Western blot and immunohistochemistry to verify the expression levels of target molecules. …”
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    Article
  6. 2866

    La Inserción internacional de Suramérica: la apuesta por la Unasur by Carlos Alberto Chaves García

    Published 2010-09-01
    “…In like manner, the new experience of regional cohesion responds to the projection of the geostrategic interests of Argentina, Brazil, and Venezuela, as an expression of the competence of the leadership of said scheme for regional cooperation and integration.…”
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    Article
  7. 2867

    Comprehensive Analysis on the Specific Role and Function of Mitochondrial Inner Membrane Protein MPV17 in Liver Hepatocellular Carcinoma by Hanchuan Tao, Cheng Wang, Chongmei Lu, Ning Ma, Yifan Zhu, Shihai Xuan, Xiaojun Zhou

    Published 2022-01-01
    “…Next, the relationship between MPV17 expression and LIHC survival was analyzed and verified by AUC curves. …”
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    Article
  8. 2868

    Elevated ALOX12 in renal tissue predicts progression in diabetic kidney disease by Meixi Wang, Jingjing Wang, Jinni Wang, Yonggui Wu, Xiangming Qi

    Published 2024-12-01
    “…This study aims to identify the main differentially expressed genes in DKD from transcriptome sequencing results and analyze their diagnostic value. …”
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    Article
  9. 2869

    Morphological and Molecular Characterization of Toxigenic Aspergillus flavus from Groundnut Kernels in Kenya by Robert O. Okayo, Darius O. Andika, Mathews M. Dida, George O. K’Otuto, Bernard M. Gichimu

    Published 2020-01-01
    “…All the remaining 14 isolates expressed at least one of the aflatoxigenic genes but only 5 had all the genes expressed. …”
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    Article
  10. 2870

    Bioinformatics approach reveals the critical role of inflammation-related genes in age-related hearing loss by Xi Gu, Chenyu Chen, Yuqing Chen, Chaojun Zeng, Yanchun Lin, Ruosi Guo, Shujin Xu, Chang Lin

    Published 2025-01-01
    “…Initially, a total of 105 Inflammatory related differentially expressed genes (IRDEGs) were obtained by overlapping the differentially expressed genes from the GSE49522 and GSE49543 datasets with Inflammatory related genes. …”
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    Article
  11. 2871

    Pancreatic Acinar Cells Employ miRNAs as Mediators of Intercellular Communication to Participate in the Regulation of Pancreatitis-Associated Macrophage Activation by Yong Zhao, Hao Wang, Ming Lu, Xin Qiao, Bei Sun, Weihui Zhang, Dongbo Xue

    Published 2016-01-01
    “…A total of 115 differentially expressed miRNAs were identified, and 30 showed upregulated expression, while 85 displayed downregulated expression. …”
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    Article
  12. 2872

    Cell autonomous TLR4 signaling modulates TGF-β induced activation of human cardiac fibroblasts by Gayathri Vijayakumar, Anisha Latha, Aiswaria P. Anil, Yogini Surve, Aiswarya R, Bipin G. Nair, Indulekha CL. Pillai

    Published 2025-02-01
    “…TGF-β treated cardiac fibroblastss show enhanced cytokine expression, and inhibition of TLR4 signaling reduces the expression of cytokines, thereby reducing TGF-β targets such as extracellular matrix genes. …”
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    Article
  13. 2873

    Multiple Myeloma and B Cell Lymphoma. Investigation of IL-6, IL-6 Receptor Antagonist (IL-6RA), and GP130 Antagonist (GP130A) Using Various Parameters in an In Vitro Model by Eva Kovacs

    Published 2006-01-01
    “…Our results showed that (1) all five MM cell lines (OPM-2, RPMI-8226, U-266, KMS-12-BM, MOLP-8) expressed surface IL-6R and gp130, the B cell lymphomas (WSU-1, DOHH-2, U-698) expressed only gp130; (2) exogenous IL-6 markedly up-regulated the expression of membrane IL-6R (up to 186%) and down-regulated the gp130 receptor (down to 4%) in MM cell lines, the membrane expression of gp130 in B cell lymphomas was not altered; (3) IL-6 markedly increased the spontaneous proliferation (up to 151%) in all MM cell lines, that of B cell lymphomas was not affected; (4) IL-6 increased the DNA synthesis in the S cell cycle phase of MM cells and arrested the stage G2/M, IL-6 was ineffective in any cell cycle phase of B cell lymphoma; (5) IL-6RA inhibited the membrane IL-6R partially, the proliferation was decreased only slightly; and (6) although gp130A inhibited the membrane gp130 completely, the proliferation was decreased 81—78% in MM and B cell lymphoma cell lines. …”
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    Article
  14. 2874

    RNA modification writer-based immunological profile and genomic landscape of tumor microenvironment in lung adenocarcinoma by Qiang Xu, Lingyu Kong, Zhezhu Han, Xiuying Jin, Mingyan Ding, Zhengri Piao, Songnan Zhang

    Published 2025-01-01
    “…Then, we used differentially expressed gene (DEGs) to develop a signature for predicting patient outcomes, which was dubbed the “writer score” for RNA-modified writers. …”
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    Article
  15. 2875

    Multiomics Integrated Analysis Identifies SLC24A2 as a Potential Link between Type 2 Diabetes and Cancer by Qin Bian, Haijun Li, Xiaoyi Wang, Tingting Liang, Kai Zhang

    Published 2022-01-01
    “…In addition, SLC24A2 was only expressed in islet β cells and showed abnormal expression in 17 kinds of cancers and significantly correlated with the prognosis of 10 kinds of cancers. …”
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    Article
  16. 2876

    Integrated transcriptome and metabolome analysis of liver reveals unsynchronized growth mechanisms in blunt-snout bream (Megalobrama amblycephala) by Qi Liu, Xue Zou, Ming Zhao, Qianqian Guan, Zhaoyang Xuan, Lusha Liu, Zexia Gao

    Published 2025-01-01
    “…A total of 2,097 differentially expressed genes (DEGs) were identified between FG and SG, with 830 genes exhibiting significantly higher expression level in FG. …”
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    Article
  17. 2877

    Genome-wide identification and characterization of transcription factors involved in defense responses against Sclerotinia sclerotiorum in Brassica juncea by Xu Yang, Shaomin Guo, Hairun Jin, Jinze Zhang, Lijing Xiao, Qingjing Ouyang, Xu Long, Zhongbin Yan, Entang Tian

    Published 2025-02-01
    “…The number of differentially expressed TFs (DETs) between the HR and the LR lines peaked at 24 HAI, with 202 upregulated and 105 downregulated TFs. …”
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    Article
  18. 2878

    Mān on the Referentiality Continuum in Thai by Kaenmuang, Jinawat, Piyamahapong, Piroon, Pittayaporn, Pittayawat

    Published 2025-01-01
    “…However, the pronoun mān in Thai sometimes occurs without any co-referring explicit nominal expression, leading previous studies to consider them as non-referential. …”
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    Article
  19. 2879

    Tacrolimus Protects Podocytes from Apoptosis via Downregulation of TRPC6 in Diabetic Nephropathy by Ruixia Ma, Ying Wang, Yan Xu, Rui Wang, Xianghua Wang, Ning Yu, Minghui Li, Yan Zhou

    Published 2021-01-01
    “…The transient receptor potential channel 6 (TRPC6) is expressed in podocytes and mediates podocyte injury induced by high glucose levels. …”
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    Article
  20. 2880

    Identification of molecular characteristics in polycystic ovary syndrome using single-cell and transcriptome analysis by Xiaolin Zhu, Yanhua Han, Yuenan Feng, Yuanli Shan, Chang Liu, Kexin Wang, Xiaoke Li, Shidi Zhang, Yaguang Han

    Published 2025-01-01
    “…The expression of genes was detected by RT-qPCR. Through differential analysis, we identified 230 common differentially expressed genes (DEGs) in GSE138518 and GSE155489. …”
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    Article