Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor ef... by Zhifei Ma, Wen Chen, Aiping Zhang, Xiaokang Shen, Lin Zheng

“…Differential expressed MPTDN-related genes in NSCLC and control were screened, and molecular clusters were obtained. …”
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A meta-analysis of whole blood transcriptome reveals genes associated with increased neutrophil activity and T cell suppression in sepsis by T. N. Shruthi, Anbazhagan Kolandaswamy, Prabakara Somanna

“…Results Gene expression data resulted in 233 differentially expressed genes (DEGs), 146 genes were up-regulated and 87 genes were down-regulated. …”
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The miRNA‐mRNA Regulatory Network in Human Hepatocellular Carcinoma by Transcriptomic Analysis From GEO by Razieh Heidari, Vahideh Assadollahi, Seyedeh Negar Marashi, Fatemeh Elahian, Seyed Abbas Mirzaei

“…Aim In this study, we analyzed expression profile datasets and miRNA expression profiles related to HCC from the GEO using R software to detect differentially expressed genes (DEGs) and differentially expressed miRNAs (DEmiRs). …”
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Downregulation of S100 Calcium Binding Protein A9 in Esophageal Squamous Cell Carcinoma by Harsh Pawar, Srinivas M. Srikanth, Manoj Kumar Kashyap, Gajanan Sathe, Sandip Chavan, Mukul Singal, H. C. Manju, Kariyanakatte Veeraiah Veerendra Kumar, M. Vijayakumar, Ravi Sirdeshmukh, Akhilesh Pandey, T. S. Keshava Prasad, Harsha Gowda, Rekha V. Kumar

“…We had previously employed a quantitative proteomic approach to identify differentially expressed proteins in ESCC tumors. A total of 238 differentially expressed proteins were identified in that study including S100 calcium binding protein A9 (S100A9) as one of the major downregulated proteins. …”
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FLT3 is associated with dendritic cell infiltration, tertiary lymphoid structure construction, and predict response to checkpoint inhibitors immunotherapy in solid cancers by Yongchang Tang, Hong Wang, Jiankun Zhang, Chunhui Yang, Fei Xu, Yan Song, Tianen Li, Qiangbo Zhang

“…We analyzed the frequency of FLT3 alterations, its mRNA expression levels, and its prognostic implications across multiple cancer types. …”
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Kruppel-family zinc finger proteins as emerging epigenetic biomarkers in head and neck squamous cell carcinoma by Patrick Pearson, Kendra Smith, Nilita Sood, Elizabeth Chia, Alicia Follett, Michael B. Prystowsky, Simon Kirby, Thomas J. Belbin

“…Abstract Background Krüppel-type zinc finger protein genes located on chromosome 19q13 are aberrantly hypermethylated with high frequency in all anatomic sub-sites of head and neck cancers as well as other epithelial tumours resulting in decreased expression. Methods We examined prognostic significance of ZNF154 and ZNF132 expression and DNA methylation in independent patient cohort of about 500 head and neck cancer patients in the Cancer Genome Atlas (TCGA). …”
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Identification of Key Genes and Prognostic Value Analysis in Hepatocellular Carcinoma by Integrated Bioinformatics Analysis by Meng Wang, Licheng Wang, Shusheng Wu, Dongsheng Zhou, Xianming Wang

“…Emerging evidence indicates that various functional genes with altered expression are involved in the tumor progression of human cancers. …”
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The Potential Impact of HNRNPA2B1 on Human Cancers Prognosis and Immune Microenvironment by Tao Huang, Gang Zhu, Fan Chen

“…HNRNPA2B1 expression was also closely linked to TMB, MSI, tumor stemness, and chemotherapy response. …”
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Treatment of Cancer Gene Changes in Chronic Myeloid Leukemia by Big Data Analysis Platform-Based Dasatinib by Linlin Song, Qi Li, Hui Shi, Pengxia Zhang

“…At the same time, the gene expression profile was analyzed by principal component analysis (PCA) in the analysis system. …”
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Aging impairs CD8 T cell responses in adoptive T-cell therapy against solid tumors by Gulfiya Kadyrzhanova, Miho Tamai, Shukla Sarkar, Rajkumar Singh Kalra, Hiroki Ishikawa

“…Conversely, retroviral expression of Epas1 enhances anti-tumor activity of aged CD8 TCR-T cells. …”
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Desmoglein-2 was a novel cancer-associated fibroblasts-related biomarker for oral squamous cell carcinoma by Jin Liu, Zhonghao Sun, Shihui Cao, Hao Dai, Ze Zhang, Jingtao Luo, Xudong Wang

“…Furthermore, patients with low DSG2 expression were more likely to benefit from immunotherapy than those DSG2 highly expressed patients. …”
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4-1BB agonist targeted to fibroblast activation protein α synergizes with radiotherapy to treat murine breast tumor models by Ignacio Melero, Alvaro Teijeira, Christian Klein, Maria E Rodriguez-Ruiz, Christina Claus, Pablo Umana, Tamara Tanos, Carlos E De Andrea, Carlos Luri-Rey, Paloma Sanchez-Mateos, Leticia Fernández-Rubio, María Collantes, Irantzu Serrano-Mendioroz, Celia Barrio-Alonso, Antonio Rullan, Jon Ander Simon, Eneko Garate-Soraluze, Claudia del Pilar Herrero

“…Human colorectal cancer samples pre and post irradiation showed enhanced FAP expression after radiotherapy.Conclusion Increased FAP expression in the TME as a result of radiotherapy can be exploited to target agonist 4-1BB immunotherapy to malignant tumor lesions using an FAP-4-1BBL antibody fusion protein.…”
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Protective Role of rAAV-NDI1, Serotype 5, in an Acute MPTP Mouse Parkinson's Model by Jennifer Barber-Singh, Byoung Boo Seo, Akemi Matsuno-Yagi, Takao Yagi

“…Using recombinant adenoassociated virus vectors (serotype 5) carrying our NDI1 gene, we were able to express the Ndi1 protein in the substantia nigra (SN) of C57BL/6 mice with an expression period of two months. …”
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HLA Class II Defects in Burkitt Lymphoma: Bryostatin-1-Induced 17 kDa Protein Restores CD4+ T-Cell Recognition by Azim Hossain, Jason M. God, Faisal F. Y. Radwan, Shereen Amria, Dan Zhao, Jennifer R. Bethard, Azizul Haque

“…The restoration of immune recognition appeared to be linked with an increased expression of a 17 kDa peptidylprolyl-like protein. …”
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Feasibility study of emotion mimicry analysis in human–machine interaction by Herag Arabian, Tamer Abdulbaki Alshirbaji, Ashish Bhave, Verena Wagner-Hartl, Marcel Igel, J. Geoffrey Chase, Knut Moeller

“…The proposed system functions as a digital mirror, initially displaying an animated avatar’s face expressing a predefined emotion. Users are then asked to mimic the avatar’s expression. …”
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Resistance Response of the Jasmonic Acid and Salicylic Acid Signaling Pathways in Mango Fruits Infected with Lasodiplodia theobromae by QU Xiangxiang, HU Meijiao, SUN Jinhua, GONG Deqiang, GAO Zhaoyin, CHEN Gengxin, LI Min

“…The gene expression of isochorismate synthase (MiICS), a SA signaling pathway-related gene, was down-regulated, while the gene expression of non-expressor of pathogenesis-related genes 1 (MiNPR1) was up-regulated at the early stage and down-regulated at the late stage. …”
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“Gestures of Air and Stone”: Translating Ethan Frome into Dance in Cathy Marston’s Snowblind by Adeline Chevrier-Bosseau

“…This article retraces the presence of dance and somatic expression in Edith Wharton’s writing, in order to show how Ethan Frome could organically lend itself to a choreographic translation. …”
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The Role of the IL-20 Subfamily in Glaucoma by Mary K. Wirtz, Kate E. Keller

“…The DBA/2J mouse develops high intraocular pressures with age and has characteristic optic nerve defects that make it a useful glaucoma model. IL-24 expression is significantly upregulated in the retina of these mice, while IL-20RA expression in the optic nerve is downregulated following pressure-induced damage. …”
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Regulation of Annexin I in Rheumatoid Synovial Cells by Glucocorticoids and Interleukin-1 by Eric F. Morand, Pam Hall, Paul Hutchinson, Yuan H. Yang

“…The glucocorticoid (GC)-induced antiinflammatory molecule annexin I is expressed in leukocytes and has antiinflammatory effects in animal models of arthritis, but the expression of annexin I in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) is unknown. …”
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CCN1 promotes APRIL/BAFF signaling in esophageal squamous cell carcinoma but attenuates it in esophageal adenocarcinoma by Lingling Xing, Zhenyu Jiang, Ruize Xu, Tong Dang, Jinbao Wu, Jianyuan Chai, Xianmei Meng

“…Expression of CCN1 in EAC cells leads to TRAIL-mediated apoptosis. …”
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